• The randomized controlled phase III Neuroendocrine Tumors Therapy (NETTER-1) trial evaluated the efficacy and safety of 177Lu-DOTATATE as compared with high-dose octreotide long-acting repeatable (LAR) in patients with advanced progressive somatostatin-receptor positive midgut neuroendocrine tumors. (wikipedia.org)
  • This study aimed to evaluate the long-term prognostic usefulness of 18 F-FDG PET for patients with metastatic gastroenteropancreatic neuroendocrine tumors (GEPNETs). (snmjournals.org)
  • Gastroenteropancreatic neuroendocrine tumors (GEPNETs) are rare and form a heterogeneous group of tumors, with different progression profiles ( 1 ). (snmjournals.org)
  • Different histoprognostic classifications ( 2 - 4 ) have been proposed, but determining the prognosis for neuroendocrine tumors (NETs) remains problematic even in the case of metastatic disease. (snmjournals.org)
  • VIPomas are neuroendocrine tumors that secrete vasoactive intestinal peptide (VIP) autonomously. (medscape.com)
  • Approximately 10% of neuroendocrine tumors of the gastrointestinal (GI) tract (except carcinoids) are VIPomas. (medscape.com)
  • Neuroendocrine Tumors of the Bronchopulmonary System (Typical and Atypical Carcinoid Tumors): Current Strategies in Diagnosis and Treatment. (karger.com)
  • Streptozocin chemotherapy for advanced/metastatic well-differentiated neuroendocrine tumors: an analysis of a multi-center survey in Japan. (cancerindex.org)
  • Neuroendocrine tumors (NETs) are believed to be relatively rare and to follow a generally indolent course. (cancerindex.org)
  • Therapeutic options in patients with advanced-stage gastroenteropancreatic (GEP) neuroendocrine tumors are limited. (snmjournals.org)
  • Therapeutic options in patients with progressive and disseminated metastatic neuroendocrine gastroenteropancreatic (GEP) tumors are often limited, and prognosis is often poor ( 1 , 2 ). (snmjournals.org)
  • The epithelial-mesenchymal transition (EMT) contributes to the metastatic cascade in various tumors. (bvsalud.org)
  • Pancreatic neuroendocrine tumors may be functional or nonfunctional. (medscape.com)
  • Nonfunctioning tumors usually are larger and present because of their size or metastatic spread. (medscape.com)
  • Overall, the age-adjusted incidence of neuroendocrine tumors increased sixfold from 1973 (1.09 per 100,000) to 2012 ((6.98 per 100,000), possibly because of increased early detection. (medscape.com)
  • No universally agreed-upon algorithm exists in the radiologic investigation of pancratic neuroendocrine (islet cell) tumors of the pancreas. (medscape.com)
  • Therapy must be conducted by the doctor, experienced in the treatment of metastatic clear cell renal cell carcinoma or gastrointestinal stromal tumors. (medexmd.com)
  • Sutent 12,5 mg is intended for the treatment of inoperable and/or metastatic pancreatic neuroendocrine tumors with disease development in adult people. (medexmd.com)
  • In neuroendocrine tumors (NETs), liver metastases (LM) represent the most crucial prognostic factor, irrespective of the primary tumor site. (oaepublish.com)
  • At diagnosis, about 65-95% of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) show hepatic metastasis. (oaepublish.com)
  • Neuroendocrine tumors (NETs) are rare neoplasms originating from diffuse neuroendocrine cells. (oaepublish.com)
  • [ 2 ] Well- to moderately differentiated neuroendocrine neoplasms (WMD-NEN) are a highly heterogeneous group of tumors comprising low-grade (G1) and intermediate-grade (G2) NETs of the gastrointestinal tract, typical and atypical carcinoids of the lung and thymus, and other cancers such as medullary thyroid carcinoma and pheochromocytoma/paraganglioma. (oaepublish.com)
  • It is most commonly used for evaluating primary and metastatic well-differentiated neuroendocrine tumors . (radiopaedia.org)
  • Safety and Efficacy of 68Ga-DOTATATE PET/CT for Diagnosis, Staging, and Treatment Management of Neuroendocrine Tumors. (radiopaedia.org)
  • Clinical History of the Theranostic Radionuclide Approach to Neuroendocrine Tumors and Other Types of Cancer: Historical Review Based on an Interview of Eric P. Krenning by Rachel Levine. (thieme-connect.de)
  • A wide variety of neuroendocrine tumors stain positive for chromogranin A. (medscape.com)
  • it is usually higher in large, metastatic, and well-differentiated tumors. (medscape.com)
  • Chromogranin A is a reliable serum diagnostic biomarker for pancreatic neuroendocrine tumors but not for insulinomas. (medscape.com)
  • Chromogranin A, Ki-67 index and IGF-related genes in patients with neuroendocrine tumors. (medscape.com)
  • As a senior consultant of oncology specialized in endcrine tumors and radionuclide therapy, my research focuses on optimizing peptide receptor radionuclide therapy for patients with neuroendocrine tumors. (lu.se)
  • Neutrophil-to-lymphocyte ratio (NLR) is prognostic in the majority of solid tumours but is reported to have less value in indolent well-differentiated NETs. (enets.org)
  • Peptide receptor radionuclide therapy (PRRT) is a type of radionuclide therapy, using a radiopharmaceutical that targets peptide receptors to deliver localised treatment, typically for neuroendocrine tumours (NETs). (wikipedia.org)
  • Glucagonomas of the pancreas are neuroendocrine tumours (NETs) that arise from well-differentiated neuroendocrine cells within the pancreatic islets. (dundee.ac.uk)
  • Neuroendocrine Tumours (NETs) are rare tumours that affect specialised cells known as neuroendocrine cells. (theranostics.sg)
  • Where Are Neuroendocrine Tumours (NETs) Typically Found? (theranostics.sg)
  • Approximately 30% of NETs occur in the bronchial system, making it the second most common area of the body for neuroendocrine tumours. (theranostics.sg)
  • What Are the Symptoms of Neuroendocrine Tumours (NETs)? (theranostics.sg)
  • How Are Neuroendocrine Tumours (NETs) Diagnosed? (theranostics.sg)
  • What Are the Treatment Options Available for Neuroendocrine Tumours (NETs)? (theranostics.sg)
  • Streptozocin-Based Chemotherapy in Patients with Advanced Neuroendocrine Neoplasms--Predictive and Prognostic Markers for Treatment Stratification. (cancerindex.org)
  • Chemotherapy with streptozocin (STZ) in combination with 5-FU or doxorubicin (Dox) represents a standard of care for patients with metastatic pancreatic neuroendocrine neoplasms (pNEN). (cancerindex.org)
  • STZ-based chemotherapy is an effective and well-tolerated treatment option in patients with well differentiated neuroendocrine neoplasms. (cancerindex.org)
  • Highly aggressive, poorly differentiated neoplasms were defined as Grade-3 neuroendocrine carcinomas (NECs) when originating from the gastrointestinal tract, or as small- or large-cell NECs when appearing in the lung. (oaepublish.com)
  • Pulmonary carcinoids are well differentiated low to intermediate grade lung neuroendocrine tumours (LNETs), that belong to the group of lung neuroendocrine neoplasms which also include highly aggressive lung neuroendocrine carcinomas (LNECs). (who.int)
  • These data have been combined with previously published LNET data to perform integrative analysis using multi-omics factor analysis (MOFA), resulting in a molecular map of lung neuroendocrine neoplasms for exploration. (who.int)
  • pancreatic neuroendocrine tumours (tumours of the hormone-producing cells in the pancreas) that have spread or cannot be removed with surgery. (europa.eu)
  • Sunitinib Accord is used if the disease is getting worse and the tumour cells are well-differentiated (similar to normal cells in the pancreas). (europa.eu)
  • The pancreas takes 7% of appearances, formerly known as islet cell tumours. (theranostics.sg)
  • Pancreatic neuroendocrine tumour is an uncommon cancer arising in the pancreas. (medexmd.com)
  • PURPOSE Neuroendocrine tumours of the pancreas (pNET) are observed in 8 - 17 % of patients with von Hippel-Lindau disease (vHLD), and 11 - 20 % of these patients develop metastatic disease. (doctorksa.com)
  • Normally these tumours are located in the pancreas or duodenum. (ronnyallan.net)
  • NET RETREAT the CCTG NE1 trial has recently opened in North America looking to compare retreatment of Peptide Receptor Radionuclide Therapy versus standard treatment in patients with metastatic midgut neuroendocrine tumours. (queensu.ca)
  • 5458 - Baseline characteristics from CLARINET FORTE: Evaluating lanreotide autogel (LAN) 120 mg every 14 days in patients with progressive pancreatic or midgut neuroendocrine tumours during a standard first-line LAN regimen. (esmo.org)
  • Streptozotocin-induced diabetic ketoacidosis in a patient with metastatic islet-cell carcinoma. (cancerindex.org)
  • Merkel cell carcinoma (MCC) is an uncommon neuroendocrine cutaneous carcinoma. (springeropen.com)
  • The histopathology examination showed infiltration of the thyroid gland by a neuroendocrine carcinoma with characteristics compatible with MCC. (springeropen.com)
  • Merkel Cell Carcinoma (MCC) is an uncommon neuroendocrine cutaneous carcinoma which is characterized by high incidence of early loco-regional relapse and distant metastases (Poulsen 2004 ). (springeropen.com)
  • Untreated locally advanced and/or metastatic clear cell renal cell carcinoma. (medexmd.com)
  • Locally advanced and/or metastatic clear cell renal cell carcinoma, if the previous cytokine therapy was ineffective. (medexmd.com)
  • Sutent is intended for the use of advanced and/or metastatic renal cell carcinoma in adult people. (medexmd.com)
  • Metastatic renal cell carcinoma is a type of renal cancer that suggests malignant transformations in the renal tubule cells. (medexmd.com)
  • Another change is the subclassification of adenocarcinoma: the definition of bronchioalveolar carcinoma has been restricted to noninvasive tumours. (ersjournals.com)
  • Large cell neuroendocrine carcinoma (LCNEC) is now recognized as a histologically high grade non small cell carcinoma showing histopathological features of neuroendocrine differentiation as well as immunohistochemical neuroendocrine markers. (ersjournals.com)
  • As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
  • In addition of the categories of squamous dysplasia and carcinoma in situ , two additional lesions were added to the group of pre-invasive lesions: atypical adenomatous hyperplasia (AAH) and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH). (ersjournals.com)
  • With a gamma emitter as the radionuclide, the technique can be used for imaging with a gamma camera or PET scanner to locate tumours. (wikipedia.org)
  • Yttrium-90-DOTA-Tyr(3)]-octreotide (DOTATOC) and [(177)Lu-DOTA-Tyr(3)-Thr(8)]-octreotide (DOTATATE) are used for peptide receptor-mediated radionuclide therapy (PRMRT) in neuroendocrine tumours. (nih.gov)
  • 3253 - The impact of tumour absorbed dosimetry with survival outcomes after peptide receptor radionuclide therapy in metastatic neuroendocrine tumours. (esmo.org)
  • Radiotheranostics are small-molecule or carrier-bound radiopharmaceuticals that can be used for diagnostic imaging and radionuclide therapy, especially for the treatment of various tumour diseases. (thieme-connect.de)
  • Positron emission tomography (PET) in contrast is, however, regarded as being a quantitative imaging modality that, in addition to providing images of the distribution of positron-emitting radionuclides in the body, allows measurements of radionuclide uptake in organs and tissues (e.g. standardised uptake value (SUV)) for a variety of reasons such as attempting to determine the metabolic activity of a tumour, prognostication or assessment of response to chemotherapy or radiotherapy. (springeropen.com)
  • Additionally, adolescents with locally advanced unresectable or metastatic solid malignancies will also be enrolled. (pharmaphorum.com)
  • 131I] MIBG-avid unresectable or metastatic PPGLs are treated with [131I] MIBG therapy. (bvsalud.org)
  • Poor metabolic response (measured with MTV and TLG) to [131I] MIBG therapy in unresectable or metastatic PPGLs was related to shorter OS. (bvsalud.org)
  • I was diagnosed with metastatic pancreatic neuroendocrine tumour with large volume liver metastases in. (taparu.com)
  • Orthotopic liver transplantation (OLT) represents a generally accepted albeit somewhat controversially discussed therapeutic strategy in highly selected patients with non-resectable hepatic metastases from neuroendocrine tumours (NET). (ox.ac.uk)
  • The rare case of metastatic infiltration of the thyroid gland by a MCC based on histological and immunohistochemical findings was described. (springeropen.com)
  • In this regard, it is worth highlighting the treatment with I-131 for differentiated thyroid cancer, lutetium 177-peptides for metastatic neuroendocrine tumours, or lutetium 177-PSMA for prostate cancer . (ivo.es)
  • An example of a promising treatment currently under investigation is lutetium-177-PSMA for treatment in patients with metastatic castration-resistant prostate cancer. (advancingnuclearmedicine.com)
  • Lutetium-177-PSMA-617 for Metastatic Castration-Resistant Prostate Cancer. (thieme-connect.de)
  • Palbociclib in combination with trastuzumab with or without pertuzumab and endocrine therapy is currently in clinical development for use as a maintenance therapy for patients with hormone receptor positive (HR+) and human epidermal growth factor receptor 2 positive (HER2+) metastatic breast cancer who have had prior treatment. (nihr.ac.uk)
  • Pancreatic islet cells are part of the diffuse neuroendocrine system of the gut and pancreatic endocrine system. (medscape.com)
  • Imaging is used to localize primary and metastatic lesions and to determine resectability or alternative palliative and curative treatment options. (medscape.com)
  • gastrointestinal stromal tumour (GIST), a type of cancer of the stomach and bowel where there is uncontrolled growth of cells in the supporting tissues of these organs. (europa.eu)
  • Sutent is intended for the treatment of metastatic and/or inoperable malignant gastrointestinal stromal tumour in adult people (if the treatment with Imatinib wasn't successful or if the patient's body is resistant to this substance). (medexmd.com)
  • G Gastrointestinal stromal tumour is a cancer of GI tract, arising from uncontrolled cell growth of the connective tissues of stomach and intestines. (medexmd.com)
  • Tumour classification systems provide the foundation for tumour diagnosis and patient therapy and a critical basis for epidemiological and clinical studies. (ersjournals.com)
  • Serum CgA can be used to monitor neuroendocrine tumor progression after a surgical intervention as well as medical therapy, with the only exception being somatostatin analogs that inhibit tumor secretion rather than causing tumor reduction. (medscape.com)
  • In 2017, the EMA approved Lu-177-Dotate (based on Lu-177 c.a.), which can be used to treat this type of tumour. (advancingnuclearmedicine.com)
  • A high proportion of patients have advanced or metastatic disease which means the cancer has spread around the body at diagnosis and are currently managed with palliative chemotherapy or supportive care. (nihr.ac.uk)
  • Subsequently, we evaluated the relationships between metabolic response and age, sex, tumour type, metastatic site, chemotherapy or external radiation history, and 24-hour urine catecholamine levels by univariate logistic regression analyses. (bvsalud.org)
  • Although pulmonary carcinoids show relatively good prognosis in comparison to carcinomas, metastatic disease and relapse do occur. (who.int)
  • Neuroendocrine Tumor Diagnosis and Management: Ga-DOTATATE PET/CT. (radiopaedia.org)
  • In 2015, the hospital's nuclear medicine centre was the first in the province to treat inoperable and metastatic neuroendocrine tumours with the Lutetium (177) Lu-DOTATATE procedure. (netcare.co.za)
  • As there are significant advantages to no-carrier added lutetium-177, additional solutions are being developed and tested to treat NET tumours. (advancingnuclearmedicine.com)
  • A number of Dutch UMC's have been involved with clinical tests that are evaluating the effect of radioactive lutetium-177 n.c.a. in the treatment of metastatic kidney cancer. (advancingnuclearmedicine.com)
  • Overall, 18 F-FDG PET appears to be of major importance in the prognostic evaluation of metastatic GEPNET. (snmjournals.org)
  • This works because some tumours have an abundance (overexpression) of peptide receptors, compared to normal tissue. (wikipedia.org)
  • A radioactive substance can be combined with a relevant peptide (or its analogue) so that it preferentially binds to the tumour. (wikipedia.org)
  • CgA is co-stored with a tissue-specific peptide hormone or neuropeptide and exerts an autocrine and paracrine effect on secretory activity of the neuroendocrine cells. (medscape.com)
  • The service actively participates in the hospital's different Tumour Committees (breast, gastrointestinal, lung, head and neck, lymphoma, melanoma, etc.), where a multidisciplinary team of professionals sets the therapeutic strategy for each patient and their monitoring. (ivo.es)
  • These types of tumours used to be called carcinoids. (theranostics.sg)
  • Additionally, we identified six tumours, termed supra-carcinoids, that displayed genuine carcinoid-like morphology, but had clinical and molecular characteristics of LNECs. (who.int)
  • ParetoTI theory identified four tumour archetypes within the tetrahedron, corresponding to the three previously reported molecular groups, and the fourth enriched for the aggressive supra-carcinoids. (who.int)
  • Neuroendocrine tumours (NET's) originate from neuroendocrine cells and present with hypersecretory syndromes characterised by flushing, diarrhoea and wheezing. (mapi-trust.org)
  • We aim to develop a computerised decision aid which will offer a decision analysis based opinion/recommendation as to the optimal course of action for patients with incurable metastatic NET's. (mapi-trust.org)
  • and microsatellite instability-high (MSI-H) or tumour mutational burden-high (TMB-H) cancers that have progressed on standard therapies. (pharmaphorum.com)
  • Many other cancers may spread to the liver, but they are metastatic cancer, not primary to the liver. (survivornet.ca)
  • Some cancers can be controlled for a number of years with modern treatments, and new treatments are being developed all the time, so it is possible to live with metastatic cancer for a long time. (cancer.ie)
  • These enzymes can be found at the surface of cancer cells, where they are involved in the growth and spread of cancer cells, and in the blood vessels that supply the tumours, where they are involved in the development of new blood vessels. (europa.eu)
  • Zanidatamab is being developed for adult patients with advanced or metastatic human epidermal growth factor-2 (HER2)-positive biliary tract cancer (BTC). (nihr.ac.uk)
  • HER2 is linked to increased tumour growth when found in high levels on cancer cells. (nihr.ac.uk)
  • Breast cancer occurs when abnormal cells in the breast begin to grow and uncontrollably divide, and eventually form a growth (tumour). (nihr.ac.uk)
  • Metastatic breast cancer is cancer that has spread beyond the breast to other parts of the body, and usually cannot be treated with surgery. (nihr.ac.uk)
  • Their operation is based on the fact that the increased consumption of glucose in tumour cells facilitates the localisation of lesions with a high degree of accuracy, allowing the local extension of the cancer to be defined, as well as the existence of more distant signs of disease and, lastly, it allows for an early assessment of the response to the treatment applied. (ivo.es)
  • The participation of Nuclear Medicine in the oncological-surgical field through the performance of radioguided surgery (selective detection of the sentinel node in various tumours, mainly in breast cancer, though also in melanomas, tumours in the head and neck, or gynaecological or urological tumours, or radiolocation of hidden lesions). (ivo.es)
  • When a tumour is localised, a tissue biopsy is performed to determine the presence of cancer cells, staging the cancer, and guide the patient's treatment. (theranostics.sg)
  • Other rare types of cancer growing in the liver are lymphomas, sarcomas and neuroendocrine tumours. (survivornet.ca)
  • Primary liver cancer may develop as a single tumour as a consequence of scarring or cirrhosis of the liver and can become very large if not diagnosed early. (survivornet.ca)
  • For some people, their first diagnosis is a diagnosis of metastatic cancer. (cancer.ie)
  • Being told you have metastatic cancer can set off overwhelming emotions of shock, disbelief and grief. (cancer.ie)
  • While some treatments can have some unpleasant side-effects, often metastatic cancer can be treated like a long-term illness, which causes problems from time to time. (cancer.ie)
  • People can live with metastatic cancer for many years. (cancer.ie)
  • No one knows how long anybody will live, but with metastatic cancer your life may be shorter than if the cancer had not spread. (cancer.ie)
  • Psycho-oncology services are specialists who can help you cope with the emotional impact of metastatic cancer. (cancer.ie)
  • Call our Support Line and ask to be put in contact with a trained volunteer who is living with metastatic cancer. (cancer.ie)
  • In 1994, the WHO adopted the International Association for the Study of Lung Cancer (IASLC) pathology panel to comprise the core membership of the WHO committee, to develop a new revised classification of lung and pleural tumours. (ersjournals.com)
  • T-DXd is an anti-HER2 antibody-drug conjugate that demonstrated high efficacy in patients with HER2-overexpressing and HER2-low metastatic breast cancer (mBC). (ctimeetingtech.com)
  • One of the key awareness messages for Neuroendocrine Cancer is the hormonal syndromes that can often accompany the diagnosis for many people. (ronnyallan.net)
  • As it's a difficult disease to diagnose, many people struggle with these syndromes for some time before formal diagnosis of Neuroendocrine Cancer. (ronnyallan.net)
  • Neuroendocrine Cancer can often be uncannily quiet, but the tumours can be 'functional' and over-secrete certain hormones to add or introduce symptoms that mimic many other diseases or conditions, such as Irritable Bowel Syndrome, Menopause, Heart disease and Asthma. (ronnyallan.net)
  • The most common category of nonmesotheliomatous cancer to involve the pleura is represented by extrapleural primary malignancies that secondarily involve the pleura via metastatic spread. (medscape.com)
  • Although they are rare, neuroendocrine tumours have an incidence of 10 cases per 100,000 inhabitants - and thanks to better diagnostic techniques - it is possible to study this disease statistically. (theranostics.sg)
  • Incidence rates and tumour localisation vary considerably between geographical regions thus implying genetic and environmental factors in disease pathophysiology. (docksci.com)
  • They were also formerly known as carcinoid tumours. (theranostics.sg)
  • [ 3 - 5 ] Metastatic spread to the liver may be accompanied by a wide spectrum of clinical presentations, from asymptomatic disease incidentally discovered during radiologic workup for other reasons, to debilitating symptoms caused by acid hypersecretion, serotonin syndrome, or carcinoid syndrome. (oaepublish.com)
  • atypical adenomatous hyperplasia and diffuse idiopathic pulmonary neuroendocrine cell hyperplasia. (ersjournals.com)
  • Neuroendocrine cells are found in all organs of the individual and help control many of their functions. (theranostics.sg)
  • However, it is known that these tumours begin when neuroendocrine cells develop changes - in other words: mutations - in their DNA, which trigger structural changes. (theranostics.sg)
  • Chromogranin A is a secretory protein, composed of 439 amino acids, found in the large dense-core vesicles of the neuroendocrine cells. (medscape.com)
  • Chromogranin A (CgA) is a secretory protein, composed of 439 amino acids, found in the large dense-core vesicles of the neuroendocrine cells. (medscape.com)
  • At the time of diagnosis of operable metastatic disease - a referral to a HPB surgeon should be considered. (bccancer.bc.ca)
  • Patients diagnosed with metastatic disease should be referred to a medical oncologist. (bccancer.bc.ca)
  • In contrast localised glucagonoma without metastatic spread may have prolonged disease free survival with radical resectional surgery. (dundee.ac.uk)
  • In general, neuroendocrine tumours are slow-growing ones, but the direct cause that triggers the disease is still unknown. (theranostics.sg)
  • However, published liver tumours remain suboptimal, and significant progress in preventing disease recurrence is required before liver transplantation can be widely applied to most patients with primary malignant liver tumours. (elsevierpure.com)
  • Recent data have suggested that OLT may represent the most efficacious approach in terms of overall and disease-free survival to the management of NET metastatic to the liver when conducted in accordance with the modified Milan criteria. (ox.ac.uk)
  • Less progress has been made in the treatment of metastatic disease. (docksci.com)
  • Zollinger-Ellison syndrome (ZES) is a condition caused by a gastrin-secreting tumour that causes hypersecretion of gastric acid leading to ulcer disease. (ronnyallan.net)
  • Another diagnostic method is the PET-FDG (glucose) that detects tumour activity through the consumption of glucose. (theranostics.sg)
  • A key advantage of PRRT over other methods of radiotherapy is the ability to target delivery of therapeutic radionuclides directly to the tumour or target site. (wikipedia.org)
  • Currently, there is a lack of effective therapeutic options for patients with advanced or metastatic BTC. (nihr.ac.uk)
  • A high metabolic tumour volume (MTV) and total lesion glycolysis (TLG) can be poor prognostic factors. (bvsalud.org)
  • In patients with incurable tumour there are several treatment options with risks and benefits varying from patient to patient. (mapi-trust.org)
  • Moreover, NRG has been at the cradle of the development of Lu-177 for the treatment of NET tumours. (advancingnuclearmedicine.com)
  • The project has led to an effective treatment for patients with NET tumours. (advancingnuclearmedicine.com)
  • One of the most accurate methods for the diagnosis of neuroendocrine tumours is nuclear medicine imaging tests. (theranostics.sg)
  • Recent progress has been made in identifying patients with malignant primary liver tumours who have the best chance of long term survival after orthotopic liver transplantation. (elsevierpure.com)
  • However, malignant SFTs, which comprise 10%-15% of SFTs, not only aggressively infiltrate adjacent structures but are also capable of metastatic spread. (medscape.com)