Head and Neck NeoplasmsCarcinoma, Squamous CellCell Line, TumorNeoplasms, Squamous CellGrape Seed ExtractGene Expression Regulation, NeoplasticReceptor, Epidermal Growth FactorMice, NudeXenograft Model Antitumor AssaysCell ProliferationAntineoplastic AgentsCisplatinApoptosisNeoplasm InvasivenessQuinazolinesBoronic AcidsPyrazinesMouth NeoplasmsTumor Cells, CulturedInhibitory Concentration 50Blotting, WesternDrug Resistance, NeoplasmSignal TransductionCell MovementCell SurvivalEpithelial-Mesenchymal TransitionImmunohistochemistryRadiation ToleranceCell Growth ProcessesDown-RegulationRNA, Small InterferingAntineoplastic Agents, PhytogenicSTAT3 Transcription FactorTransplantation, HeterologousNeoplasm TransplantationProtein Kinase InhibitorsNeoplasm ProteinsMice, SCIDReverse Transcriptase Polymerase Chain ReactionAntibodies, Monoclonal, HumanizedUp-RegulationProto-Oncogene Proteins c-aktGene Expression ProfilingTumor Suppressor Protein p53Cell DivisionDisease ProgressionPhosphorylationCell CycleDrug SynergismTransfectionRNA, MessengerEpidermal Growth FactorDose-Response Relationship, DrugFlow CytometryCyclin A1Antibodies, MonoclonalPromoter Regions, GeneticTranscription FactorsMutation