Metastasis of lung metastasis adenocarcinoma. Medical search. Frequent questions

Selective hepatic angiography may demonstrate hypervascular liver metastases by showing capillary blush in involved areas, highlighting the potential response of tumors to embolization. (medscape.com)
Small bowel metastasis from malignant tumors is generally rare and underreported. (karger.com)
These results establish HO-1 as a mediator of ATF4-dependent anoikis resistance and tumor metastasis and suggest ATF4 and HO-1 as potential targets for therapeutic intervention in solid tumors. (jci.org)
Tumors can be found in the lungs in about 2-13% of dogs. (cornell.edu)
Pancreatic tumors primarily metastasize to the liver and the lung. (damonrunyon.org)
However, it is unclear whether primary tumors and associated metastases during disease progression are metabolically different. (damonrunyon.org)
By contrast, 90.5% of the mice which received MCA followed by MWCNT had bronchiolo-alveolar adenomas and adenocarcinomas with an average of 2.9 tumors per mouse 17months after exposure. (cdc.gov)
Lung adenocarcinoma (LUAD) is one of the malignant lung tumors. (hindawi.com)
Lung cancer is one of the malignant tumors for which no effective cure has been found so far. (hindawi.com)
The most common path is the hematogenous spread, which occurs in tumors that have direct venous drainage to the lungs. (medscape.com)
The tumor initially spreads via a hematogenous route to the pulmonary arterioles and capillaries with retrograde spread from hilar nodal metastases or upper abdominal tumors, but subsequently extends through the vascular walls, invades the low resistant peribronchovascular lymphatics, and spreads along the lymphatics. (medscape.com)
Adenocarcinomas, which may occur as primary tumors or rarely reflect metastasis from intestinal carcinoma. (msdmanuals.com)

NSCLC mainly includes the histologic types of adenocarcinoma (ADC) and squamous cell carcinoma (SCC) [ 2 ]. (jcancer.org)
Volume-rendered 3-dimensional CT scan shows a metastatic mass in the trachea from squamous cell carcinoma of the lung. (medscape.com)

Mechanism of early dissemination and metastasis in Her2 + mammary cancer. (nature.com)
Early dissemination seeds metastasis in breast cancer. (nature.com)
Plain chest radiographs are routinely obtained in patients who are suspected of having cancer and are also used in the staging of cancer, but plain abdominal radiography has a limited role in the investigation of liver metastases. (medscape.com)
Cancer metastasis to the thyroid is extremely rare. (biomedcentral.com)
As to primary lung cancer metastasizing to the thyroid gland, only a few cases have been described in the literature. (biomedcentral.com)
Lung cancer is the leading cause of cancer death worldwide, with an estimated 1.4 million deaths each year [ 16 ]. (biomedcentral.com)
These findings suggest a potential novel target for early intervention against SM in lung cancer. (madiclab.com)
We detected miR-27a expression in two lung adenocarcinoma cell lines, A549 and A549/CDDP, and then investigated the effects of miR-27a on the metastasis and the chemosensitivity of cancer cells, using both gain- and loss-of-function studies. (biomedcentral.com)
To better understand the biological mechanisms of chemoresistance in lung adenocarcinoma cells and search for the reversion opportunities, we made use of a cisplatin-sensitive and derived resistant lung cancer cell line pair (A549 and A549/ CDDP). (biomedcentral.com)
Distant metastasis is the major cause of cancer-related deaths in patients with lung adenocarcinoma (LAD). (oncotarget.com)
Now, two studies provide complementary evidence demonstrating that both endogenous and exogenous antioxidants can induce stabilization of BACH1 to promote lung cancer metastasis. (nature.com)
To examine how exogenous antioxidants might influence lung cancer metastasis, Wiel et al. (nature.com)
Metastasis from endometrial cancer to small bowel is very rare [ 3 ]. (karger.com)
Lung cancer with epidermal growth factor receptor (EGFR)-activating mutations responds favorably to the EGFR tyrosine kinase inhibitors gefitinib and erlotinib. (aacrjournals.org)
High-mobility group protein box 1 (HMGB1) is overexpressed and reported to be a prognostic factor in patients with non-small-cell lung cancer (NSCLC). (jcancer.org)
Lung cancer is one of the most prevalent cancers globally and is by far the leading cause of death among males and females worldwide [ 1 ]. (jcancer.org)
the latter type comprises of 85%~90% of lung cancer diagnoses. (jcancer.org)
Lung cancer is the first leading diagnosed malignant tumor globally [ 1 ]. (medsci.org)
Non-small cell lung cancer (NSCLC) accounts for 85-90% of cases, while lung adenocarcinoma (LUAD) is the most common subtype [ 2 ]. (medsci.org)
Despite advances in diagnosis and treatment, the morbidity and mortality of lung cancer remains to mount up. (intechopen.com)
The key factor of cancer associated morbidity and mortality is principally attributable to the development of metastases. (intechopen.com)
In recent years, emerging studies have highlighted the critical role of these pathways and their regulation by microRNAs (miRNAs) in cancer invasion and metastasis. (intechopen.com)
At present, only a few areas of mRNA vaccine research have made progress, such as prostate cancer, non-small cell lung cancer, melanoma and so on ( 8 - 10 ). (frontiersin.org)
The occurrence of small intestinal metastases from primary lung cancer is rare. (spandidos-publications.com)
Postoperative pathological analysis confirmed the final diagnosis to be small intestinal metastasis from primary lung cancer. (spandidos-publications.com)
Although small intestinal metastasis from lung cancer is rare and difficult to diagnose accurately, it should be considered when encountering a patient with lung cancer exhibiting abdominal symptoms and associated imaging findings. (spandidos-publications.com)
Lung cancer is the leading cause of cancer-related death worldwide, with most patients presenting with metastases during diagnosis ( 1 ). (spandidos-publications.com)
According to the GLOBOCAN 2020 report by the World Health Organization's International Agency for Research on Cancer, ~2.2 million new cases of lung cancer occur worldwide each year, making it the world's second most common but most fatal cancer type ( 2 , 3 ). (spandidos-publications.com)
Patients with early-stage lung cancer are asymptomatic, whereas those with advanced metastasis are frequently symptomatic due to metastatic sites. (spandidos-publications.com)
Furthermore, the gastrointestinal (GI) tract is not a common site of primary lung cancer metastasis ( 4 ). (spandidos-publications.com)
This suggests that the process of GI metastasis of lung cancer is subtle and lacks specific clinical symptoms. (spandidos-publications.com)
The present report describes an uncommon case of small intestinal metastasis from lung cancer. (spandidos-publications.com)
Furthermore, the literature relevant to the occurrence, diagnosis and treatment of GI metastasis of lung cancer was reviewed. (spandidos-publications.com)
Gastric adenocarcinoma is one of the common causes of cancer death in the world. (lww.com)
This case is reported due to the rarity of cutaneous metastasis at multiple sites from a highly aggressive adenocarcinoma in a young patient, to emphasize the importance of cutaneous metastasis as a poor prognostic sign in patients with a history of cancer. (lww.com)
DRAM2 acts as an oncogene in non-small cell lung cancer and suppresses the expression of p53. (cancerindex.org)
Here, we show that DRAM2 may act as an oncogenic regulator in non-small cell lung cancer (NSCLC). (cancerindex.org)
If you have to have lung cancer, this is the slowest growing cancer which is fairly good news. (cancer.org)
3 Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York. (aacrjournals.org)
[ 5 ] An earlier report, in 1956, by Babolini and Blasi, described the same clinicopathological entity using the nomenclature, "The pleural form of primary cancer of the lung. (medscape.com)
The mechanism of how miRNAs modulate lung cancer metastasis remains unclear. (jcancer.org)
Our previous study demonstrated that miR-378 is up-regulated while miR-1827 is down-regulated in high invasive lung cancer sub-cell lines, and their biological functions have been described. (jcancer.org)
Here, we report that miR-378 and miR-1827 modulate lung cancer cell invasion and migration via epithelial-mesenchymal transition (EMT). (jcancer.org)
Restored protein expression in miRNA-overexpressed/ miRNA-suppressed cells attenuated the inhibitory/ inducing effect of the miRNA on lung cancer cells. (jcancer.org)
Collectively, our findings highlight that miR-378 and miR-1827 could serve as novel therapeutic targets in lung cancer. (jcancer.org)
Tissue microarrays from 629 resected primary lung cancers and 422 resected pulmonary epithelial metastases from various sites (whereof 275 colorectal cancer) were investigated for the immunohistochemical expression of CDH17, GPA33, MUC2, MUC6, SATB2, and SMAD4, for comparison with CDX2, CK20, CK7, and TTF-1. (lu.se)
However, no single or combination of markers can categorically distinguish primary lung cancers from metastatic GI tract cancer. (lu.se)
Leptomeningeal metastases (LM) occur in 3- 5% of patients with advanced non-small-cell lung cancer (NSCLC) and are associated with a dismal prognosis. (dovepress.com)
15 Scholars in Taiwan have found that the combination of cetuximab and afatinib is effective in controlling lung cancer with LM. (dovepress.com)
16 - 18 Nimotuzumab as another EGFR monoclonal antibody has also been reported in the application of lung cancer with LM. (dovepress.com)
Metastasis of cancer cells involves a process called epithelial-mesenchymal transition (EMT), wherein epithelial cells undergo phenotypic changes to resemble mesenchymal cells -- stem cells capable of turning into different types of adult cells. (naturalnews.com)
Hence, the inhibition of EMT is now considered a promising strategy for stopping cancer metastasis. (naturalnews.com)
The researchers found that YGJDSJ can decrease the expression of proteins important for metastasis , making it a promising natural medicine for metastatic liver cancer. (naturalnews.com)
These activities may be used for the prevention of liver cancer metastasis . (naturalnews.com)
Association of Reported Candidate Monogenic Genes With Lung Cancer Risk. (cdc.gov)
2 Diagnosis of small cell (neuroendocrine) or mucinous adenocarcinoma of cervical cancer (ie, mucinous NOS, intestinal type, signet ring cell type, invasive stratified mucin producing carcinoma and gastric type) based on 2020 WHO classification of cervical cancer. (who.int)
This study documents for the first time the clinical and epidemiological characteristics of lung cancer cases in Qatar from 1998 to 2005. (who.int)
Unlike other Gulf countries, adenocarcinoma was the predominant type in both Qatari nationals and expatriates (43.9% of lung cancer types). (who.int)
Lung cancer is currently the most frequently diagnosed major cancer and is the leading cause of cancer-related mortality in both men and women worldwide [1]. (who.int)
Cigarette smoke is the number one cause of lung cancer. (who.int)
About 90% of lung cancer cases occur in smokers or former smokers. (who.int)
The aim of the present study was to document the clinical and epidemiological characteristics of lung cancer cases in Qatar. (who.int)
It is the fourth most common cancer, accounting for 7% of female cancers, following breast, lung, and colorectal cancer. (medscape.com)
Opium use and risk of lung cancer: A multicenter case-control study in Iran. (who.int)
Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program. (who.int)
Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer. (who.int)
Hepatocellular Carcinomas from Iran: Evidence study of lung cancer among European asphalt carcinoma among postmenopausal women in the for Lack of Association between HBV Genotype workers. (who.int)

Our case is rare as it describes a case where the thyroid lesion was the revealing sign of an unknown lung carcinoma. (biomedcentral.com)
To the best of our knowledge, only a few cases of metastatic lung adenocarcinoma to the thyroid gland have been reported, describing all together four cases of thyroid lesions revealing a lung carcinoma. (biomedcentral.com)
Typical sites of metastasis of endometrial carcinoma are pelvic and para-aortic lymph nodes, vagina, peritoneum, and lungs [ 2 ]. (karger.com)
revealed for the first time carcinoma ex microcystic adenoma in which the tumor, without metastases, showed inherent malignant changes [ 7 ]. (hindawi.com)
1 ] Breast carcinoma is the most common cause of cutaneous metastasis, followed by carcinoma large intestine, lung, and ovaries in women. (lww.com)
Adenocarcinoma in situ was previously known as bronchioloalveolar carcinoma. (cancer.org)
By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
[ 3 , 4 ] The term "pseudomesotheliomatous carcinoma" was first applied by Harwood and colleagues in 1976 to 6 cases of peripheral lung adenocarcinoma that closely mimicked mesothelioma. (medscape.com)

miR-27a regulates epithelial-mesenchymal transition (EMT) and cisplatin resistance in vitro and modulates response of lung adenocarcinoma cells to cisplatin in vivo . (biomedcentral.com)
Here, we found that the expression of miR-214 was elevated in LAD and correlated positively with LAD metastasis and epithelial-mesenchymal transition (EMT). (oncotarget.com)
Recently, epithelial-mesenchymal transition (EMT) programs have become the focus of the mechanism of metastasis [ 1 , 17 - 20 ]. (intechopen.com)

Abstract：Background: Lung adenocarcinoma has a strong tendency to develop into bone metastases, especially spinal metastases (SM). (madiclab.com)

We report a case of a 37-year-old white Arabian woman who had never smoked tobacco products for whom a malignant thyroid mass revealed a primary lung tumor. (biomedcentral.com)
Malignant transformation in the tumor with metastases is rare and only about 26 cases have been reported so far. (hindawi.com)
Here we present a giant microcystic adenoma of the pancreas, possibly the largest ever malignant type in this group ever reported in the literature with extensive metastases to the liver and causing extensive compression and encasement on surrounding structures. (hindawi.com)
Axial CT scan in a 58-year-old man with malignant melanoma shows multiple round nodules and masses of varying sizes in both lungs, consistent with metastases. (medscape.com)

The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) was initially identified as a tumor-related lncRNA, which can control the proliferation and metastasis of lung adenocarcinoma ( 10 ). (spandidos-publications.com)
Overexpression of this gene is associated with tumor cell proliferation and metastasis. (cancerindex.org)

Increased miR-27a expression was also detected in tumor tissues sampled from lung adenocarcinoma patients treated with cisplatin-based chemotherapy and was proved to be correlated with low expression of RKIP, decreased sensitivity to cisplatin, and poor prognosis. (biomedcentral.com)
Finally, we correlated the expression of miR-27a and RKIP with the chemotherapeutic status and prognosis of lung adenocarcinoma patients. (biomedcentral.com)
Once distant metastasis occurs, there is almost no opportunity for surgery and the prognosis is poor. (spandidos-publications.com)

In their meta-analysis, Kinkel et al compared US, CT, MRI, and fluorodeoxyglucose (FDG) imaging in the detection of liver metastases from colorectal, gastric, and esophageal cancers and concluded that, with an equivalent specificity, FDG positron emission tomography (PET) is the most sensitive noninvasive imaging modality for the diagnosis of liver metastases. (medscape.com)
To counterbalance oxidative stress and ensure redox homeostasis, a subgroup of non-small-cell lung cancers acquire stabilizing mutations in NFE2L2 , the gene encoding NRF2, the transcriptional regulator of the cellular antioxidant response, and inactivating mutations in its negative regulator, KEAP1. (nature.com)
MUC2 was negative in all primary lung cancers, but positive only in less than half of pulmonary metastases from mucinous adenocarcinomas from other organs. (lu.se)
Combining six GI markers did not perfectly separate primary lung cancers from pulmonary metastases including subgroups such as mucinous adenocarcinomas or CK7-positive GI tract metastases. (lu.se)
Adenocarcinoma is the most common histological subtype, accounting for about half of all lung cancers [ 1 ]. (hindawi.com)
Due to the fact that most lung cancers are diagnosed as advanced after regional or distant spread of the malignancy, this disease has a high mortality rate worldwide [ 2 ]. (hindawi.com)

Immunohistochemistry demonstrated that these tumor cells were positive for both cytokeratin 7 (CK7) and thyroid transcription factor-1 (TTF-1) and were negative for both CK20 and thyroglobulin, which concords with metastatic disease from lung origin (Figs. 1 and 2 ). (biomedcentral.com)
Twenty percent of metastatic disease is isolated to the lungs. (medscape.com)

DRAM2 was preferentially upregulated in NSCLC tissues and higher expression of DRAM2 in NSCLC correlated with tumor node metastases stage and lymph node metastasis. (cancerindex.org)

Of note, distant metastases occur most commonly in the brain, liver, adrenal glands and bones. (spandidos-publications.com)
Ready-to-use antibodies, which were not diluted, were purchased from Beijing Zhongshan Golden Bridge Biological Technology Co., Ltd. Whole-body CT examination revealed no distant metastases anywhere, including the brain. (spandidos-publications.com)
Survival times are affected by a number of variables, including the size of the tumor, lymph node metastases, distant (e.g. lung) metastases and the treatment protocol. (cornell.edu)

In the abdomen, metastases will be identified as enlarged sublumbar lymph nodes in about 50% of dogs. (cornell.edu)
[ 3 ] Lymphatic spread also occurs to the mediastinal lymph nodes through the thoracic duct, with subsequent retrograde spread to the hilar lymph nodes and then the lungs. (medscape.com)
excluding metastasis to pelvic or paraaortic lymph nodes or vagina) prior to CCRT. (who.int)

In general, the imaging appearances of liver metastases are nonspecific, and biopsy specimens are required for histologic diagnosis. (medscape.com)
Only adenocarcinoma in situ is identified in the histologic sections examined. (cancer.org)

In this study, we observed that miR-27a is significantly upregulated in cisplatin-resistant human lung adenocarcinoma A549/CDDP cells compared with parental A549 cells. (biomedcentral.com)

In addition, we found that miR-214 enhanced the molecular program controlling the EMT of LAD cells and promoted LAD cell metastasis both in vitro and in vivo . (oncotarget.com)
Additionally, DRAM2 overexpression promoted cell metastasis and proliferation in vitro, while knockdown of DRAM2 expression yielded opposite result. (cancerindex.org)

CT is the imaging modality of choice for evaluating liver metastases. (medscape.com)
See the CT images of liver metastases below. (medscape.com)
Characteristic appearance of carcinoid liver metastases on a contrast-enhanced axial CT scan through the upper abdomen. (medscape.com)
Ultrasonography (US) is widely used in the investigation of suspected liver metastases. (medscape.com)
and the degree of vascularity of liver metastases. (medscape.com)
Late-phase pulse-inversion harmonic imaging is a useful technique for characterizing hepatic lesions and for demonstrating both greater numbers of liver metastases and smaller liver metastases. (medscape.com)
However, evidence supporting the use of MRI in the evaluation of liver metastases is accumulating because MRI allows the effective localization of hepatic and vascular invasion. (medscape.com)
Most liver metastases are multiple. (medscape.com)
Is lung involvement a favorable prognostic factor for pancreatic ductal adenocarcinoma with synchronous liver metastases? (lu.se)

Overlapping lung and pleural involvement in individual cases has given rise to the more inclusive term "pleuropulmonary" synovial sarcoma. (medscape.com)
Malignancies can reach the lung through 5 different pathways-hematogenous through the pulmonary or bronchial artery, lymphatics, pleural space, airway, or direct invasion. (medscape.com)
Lymphatic spread occurs either in an antegrade fashion by lymphatic invasion through the diaphragm and/or pleural surfaces or retrograde lymphatic spread from hilar lymph nodal metastasis. (medscape.com)
More common diseases, such as benign asbestos-related pleural disease and metastatic adenocarcinoma , can look radiographically identical to mesothelioma. (medscape.com)

Klein, C. A. Parallel progression of primary tumours and metastases. (nature.com)
Moreover, the LINC00852 target S100A9 had a positive regulatory role in the progression, migration, invasion, and metastasis of lung adenocarcinoma cells, both in vitro and in vivo. (madiclab.com)
Furthermore, S100A9 strongly activated the P38 and REK1/2 kinases, and slightly activated the phosphorylation of the JNK kinase in the MAPK pathway in A549 and SPCA-1 cells.Conclusion: LINC00852 targets S100A9 to promote progression and oncogenic ability in lung adenocarcinoma SM through activation of the MAPK pathway. (madiclab.com)
Conclusions: These data demonstrate that some MWCNT exposures promote the growth and neoplastic progression of initiated lung cells in B6C3F1 mice. (cdc.gov)

Collectively, this study uncovers a previously unappreciated miR-214-Sufu pathway in controlling EMT and metastasis of LAD and suggests that interfering with miR-214 and Sufu could be a viable approach to treat late stage metastatic LAD patients. (oncotarget.com)
Moreover, HO-1 expression correlated with reduced overall survival of patients with lung adenocarcinoma and glioblastoma. (jci.org)
Cutaneous metastasis may be the first presentation of internal malignancies even with a short history of disease in young patients. (lww.com)
Despite the availability of various therapies including surgery, radiation, and targeted therapies, unfortunately, there are significant barriers to effective treatment of LUAD and an overall survival of less than five years in patients with lung adenocarcinoma [ 3 ]. (hindawi.com)
7 Erlotinib is more widely used to treat patients with central nerve system (CNS) metastases including LM because of its better penetration of brain-blood barriers (BBB) than gefitinib and icotinib. (dovepress.com)
[ 1 ] The development of pulmonary metastases in patients with known malignancies indicates disseminated disease and places the patient in stage IV in TNM (tumor, node metastasis) staging systems. (medscape.com)
Chest radiography (CXR) is the initial imaging modality used in the detection of suspected pulmonary metastasis in patients with known malignancies. (medscape.com)
The microscopic spread of metastasis through lymphatics and perilymphatic connective tissue is seen histopathologically in 56% of patients with pulmonary metastasis. (medscape.com)
The spine is the most frequent area of bone metastasis in patients with systemic neoplastic disease. (bvsalud.org)

Positron-emission and computed tomography revealed liver, lung, and bone metastases. (cdc.gov)

Contrast-enhanced US in the liver-specific phase of contrast enhancement improves the detection of hepatic metastases, relative to nonenhanced conventional US. (medscape.com)

Multiple pulmonary nodules in my lung were first discovered by CT (taken because I was feeling shortness of breath) in 2005 and they were monitored every 6 months for three years and every year after that and no change in size was observed in any of the nodules until the last CT taken two weeks ago. (cancer.org)
The distinction between primary lung adenocarcinoma and pulmonary metastasis from the gastrointestinal (GI) tract may be difficult. (lu.se)
The most sensitive markers for GI origin were GPA33 (positive in 98%, 60%, and 100% of pulmonary metastases from. (lu.se)
Pulmonary metastasis is seen in 20-54% of extrathoracic malignancies. (medscape.com)
Imaging plays an important role in the screening and detection of pulmonary metastases. (medscape.com)
Several thermal ablation options are available for treatment of pulmonary metastases, which is performed under CT guidance. (medscape.com)
When the primary tumor invades the venous system, tumor cells embolize to the lungs through the pulmonary or bronchial arteries. (medscape.com)

CEACAM6 serves as a biomarker for leptomeningeal metastasis in lung adenocarcinoma. (nih.gov)

Approximately eighty percent of endometrial carcinomas are endometrioid adenocarcinomas. (medscape.com)

In our clinical case, the thyroid was the site of an unusual metastasis revealing an underlying lung adenocarcinoma not initially suspected. (biomedcentral.com)
The correlation between miR-27a level and chemoresistance was further investigated in clinical lung adenocarcinoma specimens. (biomedcentral.com)

Invasion of the tumor cells into regional blood and lymphatic vessels may be noted on the biopsy and will increase the potential for tumor spread/metastasis. (livs.org)

Therefore, chemotherapy-induced EMT in tumor cells has been linked to chemotherapeutic resistance and metastasis. (biomedcentral.com)
Our results show that miR-27a has the potential as key regulatory factors for the chemotherapy resistance and metastasis of lung adenocarcinoma. (biomedcentral.com)

Lymphatic spread occurs to the lungs, pleura, or mediastinum. (medscape.com)

A computed tomography (CT) scan of her chest along with an upper abdomen CT was then performed, and revealed a 4cm mass within the right upper lobe of her lung. (biomedcentral.com)
Postoperative pathology indicated infiltrating adenocarcinoma (right upper lobe mass) with poor differentiation and lymph node metastasis. (spandidos-publications.com)

Management of thyroid metastases should depend on the individual situation and surgical excision should be proposed whenever a patient's condition is favorable. (biomedcentral.com)

However, the lung tumor spread to the small intestine, causing intestinal obstruction. (spandidos-publications.com)

This report documents the case of a 57‑year‑old male patient initially diagnosed with non‑metastatic lung adenocarcinoma, who presented with abdominal pain 6 months later. (spandidos-publications.com)
A smaller percentage of dogs will have evidence of metastases in other abdominal organs. (cornell.edu)

In comparison, SATB2 and CK20 showed higher specificity, with expression in 5% and 10% of mucinous primary lung adenocarcinomas and both in 0% of TTF-1-negative non-mucinous primary lung adenocarcinomas (25-50% and 5-16%, respectively, for GPA33/CDX2/CDH17). (lu.se)

However, the underlying functions of STARDs in lung adenocarcinoma (LUAD) have not been clarified yet. (medsci.org)

Small interfering RNA-mediated RKIP knockdown revealed similar effects as that of ectopic miR-27a expression, while overexpression of RKIP attenuated the function of miR-27a in lung adenocarcinoma cells. (biomedcentral.com)
Mechanistically, Sufu was identified as an important miR-214 functional target for the EMT and metastasis of LAD, ectopic expression of Sufu alleviated miR-214 promoted EMT and metastasis. (oncotarget.com)
We also demonstrated that cells treated with miR-378 inhibitors or miR-1827 mimics had reduced number of metastases and ectopic vessels in the zebrafish embryo model. (jcancer.org)

[ 1 ] Lungs are the second most frequent site of metastases from extrathoracic malignancies. (medscape.com)

However, the cellular and molecular machinery underlying metastasis is relatively poorly understood so far. (intechopen.com)

Fine-needle aspiration cytology of the nodule revealed it to be metastasis from gastric adenocarcinoma. (lww.com)
Hello everyone, I am 56-year old former smoker (quit 7 years ago) and was just diagnosed with Adenocarcinoma In Situ based on needle biopsy done on a 1.3cm nodule in my right middle robe. (cancer.org)

The present study aimed to investigate the effects of S/V on the expression of metastasis‑associated lung adenocarcinoma transcript 1 (MALAT1), inflammation and apoptosis in human umbilical vein endothelial cells (HUVECs) induced by oxidized low‑density lipoprotein (ox‑LDL) and to elucidate its possible mechanism. (spandidos-publications.com)

Here, we showed that hepatocyte growth factor (HGF), a ligand of MET oncoprotein, induces gefitinib resistance of lung adenocarcinoma cells with EGFR -activating mutations by restoring the phosphatidylinositol 3-kinase/Akt signaling pathway via phosphorylation of MET, but not EGFR or ErbB3. (aacrjournals.org)

Anatomy15

Organisms7

Diseases95

Chemicals and Drugs46

Analytical, Diagnostic and Therapeutic Techniques and Equipment68

Phenomena and Processes28

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science4

Health Care16

Tumors12

Squamous cell carc2

Cancer67

Carcinoma8

Epithelial-mesenchyma3

Abstract1

Malignant4

Proliferation and metastasis2

Prognosis3

Cancers6

Metastatic disease2

NSCLC1

Distant3

Lymph nodes3

Histologic2

Human lung adenocarcinoma1

Cell metastasis2

Liver metastases9

Pleural4

Progression4

Patients9

Bone1

Hepatic1

Pulmonary7

Leptomeningeal1

Carcinomas1

Clinical2

Invasion1

Chemotherapy2

Mediastinum1

Right upper lobe2

Thyroid1

Tumor spread1

Abdominal2

Mucinous1

LUAD1

Ectopic3

Extrathoracic1

Molecular1

Nodule2

Transcript1

Mutations1