• The prognosis of angiosarcoma in the head and neck region is poor, and the risk of local recurrence and metastasis is high. (kjhno.org)
  • Radiotherapy may be recommended before surgery and has been shown to decrease the risk of local recurrence. (froedtert.com)
  • [ 1 ] The incidence of salivary gland neoplasms as a whole is approximately 5.5 cases per 100,000 individuals in the United States, with malignant neoplasms accounting for 0.9 cases per 100,000. (medscape.com)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
  • Bronchial carcinoids are now classed as low-grade malignant neoplasms because of their potential to cause local invasion, their tendency for local recurrence, and their occasional metastases to extrathoracic sites. (medscape.com)
  • Breast cancer ranks first among all malignant neoplasms in women and has a pronounced upward trend. (dk-allianz.de)
  • Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
  • The event of interest was the development of distant metastases, with or without a local recurrence. (duke.edu)
  • RESULTS: The hazard rate for developing distant metastases was not constant over time but was characterized by specific peaks, the first being approximately 9 months after surgery and the second at 18 to 20 months for men and 24 to 26 months for women. (duke.edu)
  • CONCLUSIONS: The probability of developing distant metastases after surgery for NSCLC peaks at specific and consistent time intervals after surgery, with specific differences between men and women. (duke.edu)
  • The bimodal distant metastases dynamics may be an intrinsic feature of metastatic progression in NSCLC. (duke.edu)
  • Historically, it has been described as following a relatively indolent clinical course, but cases of recurrence, local aggression, and distant metastases have recently been elucidated. (jcadonline.com)
  • It is an aggressive neoplasm characterized by early neural invasion and a high incidence of local recurrence and distant metastases, which may develop years after the initial resection. (b-ent.be)
  • Neoplasms that arise in the salivary glands are relatively rare, yet they represent a wide variety of both benign and malignant histologic subtypes as seen in the image below. (medscape.com)
  • Although researchers have learned much from the study of this diverse group of tumors over the years, the diagnosis and treatment of salivary gland neoplasms remain complex and challenging problems for the head and neck surgeon. (medscape.com)
  • Some common salivary gland neoplasms are listed in the table below. (medscape.com)
  • Salivary gland neoplasms make up 6% of all head and neck tumors. (medscape.com)
  • Salivary gland neoplasms most commonly appear in the sixth decade of life. (medscape.com)
  • Among salivary gland neoplasms, 80% arise in the parotid glands, 10-15% arise in the submandibular glands, and the remainder arise in the sublingual and minor salivary glands. (medscape.com)
  • A study from the Netherlands, by Valstar et al, found an overall 20-year recurrence rate for salivary gland pleomorphic adenomas of 6.7%, with the first recurrence arising at a median of 7 years. (medscape.com)
  • Those located in the minor salivary glands had a lower recurrence risk than did pleomorphic adenomas in the parotid glands. (medscape.com)
  • Almost half of all submandibular gland neoplasms and most sublingual and minor salivary gland tumors are malignant. (medscape.com)
  • Salivary gland neoplasms are rare in children. (medscape.com)
  • In children, 35% of salivary gland neoplasms are malignant. (medscape.com)
  • Contrasting information was derived through a literature review by Louredo et al, which indicated that in pediatric patients, most salivary gland neoplasms (75.4%) are malignant. (medscape.com)
  • Salivary gland neoplasms occurred with slightly greater frequency in girls (57.4% of patients) than in boys. (medscape.com)
  • Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
  • Secretory carcinoma (SC), also known as mammary analogue secretory carcinoma (MASC), is a rare salivary gland neoplasm with distinctive morphology that harbors a diagnostic ETV6 gene rearrangement. (bvsalud.org)
  • MASC was first described as a type of salivary gland neoplasm in 2010 and resembles breast secretory carcinoma. (bvsalud.org)
  • [ 1 ] The incidence of salivary gland neoplasms as a whole is approximately 1.5 cases per 100,000 individuals in the United States. (medscape.com)
  • The etiology of salivary gland neoplasms is not fully understood. (medscape.com)
  • Recent evidence suggests that the bicellular stem cell theory is the more probable etiology of salivary gland neoplasms. (medscape.com)
  • We almost always recommend excision of salivary neoplasms because even non-cancerous ones can transform into cancers. (oncologybuddies.com)
  • MRI gives the best soft tissue definition for salivary neoplasms. (oncologybuddies.com)
  • Patients in the report had a 5-year overall survival rate of 93.1%, although survival rates were lower in children who experienced symptoms, local recurrence, or metastasis or who did not undergo treatment with surgery or surgery plus radiotherapy. (medscape.com)
  • Subsequent radiotherapy in case of incompletely resected tumors can be an important option to avoid recurrence or metastasis even though this occurs rarely. (hindawi.com)
  • A 42-year-old woman, diagnosed with metastatic nonsmall cell lung cancer in July 2011, initially treated with chemotherapy and tyrosine kinase inhibitors, developed multiple brain metastases March 2013, with subsequent whole brain radiotherapy, after which a magnetic resonance imaging (MRI) showed a significant volume regression of all brain metastases. (surgicalneurologyint.com)
  • In many cases, an aggressive surgical treatment, which includes major bone resection and is sometimes associated with radiotherapy and chemotherapy, is required for better control of local recurrence and metastasis in such lesions. (bvsalud.org)
  • 5 Years Local Recurrencce Rates Following Post- Operative 2D Radiotherapy Treatment Planning Patients - An Institutional Experience. (who.int)
  • So, purpose of the study is to assess 5 year rates of local recurrence following post-operative 2D Radiotherapy treatment planning. (who.int)
  • The patient initially benefited from single tyrosine kinase inhibitor (TKI) therapy from July 2011 to March 2012 followed by combined chemotherapy and TKI treatment from April 2012 to December 2012, achieving next to complete regression of lung, liver, and nodal metastases. (surgicalneurologyint.com)
  • Nodal metastasis is not common. (oncologybuddies.com)
  • Their study showed that MA lacks the frequent gain of chromosomes 7 and 17 and losses of the Y chromosome that are typical of papillary renal cell neoplasms, suggesting that MA is not related to renal cell carcinoma and papillary adenoma. (wikipedia.org)
  • The aim of this study was to evaluate the patients with squamous cell carcinoma (SCC) of the lip in terms of age, sex, tumor localization, tumor size, histopathological subtype, lymph node metastasis, and recurrence rates. (medicaljournal-ias.org)
  • Extrapulmonary small-cell carcinoma (SCC) is a rare neoplasm that shares certain features with its pulmonary counterpart and occurs predominantly in the gastrointestinal tract (GIT). (mdpi.com)
  • Renal cell carcinoma (RCC), the most common kidney neoplasm, originates in renal tubular epithelial cells and accounts for 85-90% of adult renal malignancies [ 1 ]. (biomedcentral.com)
  • Predisposing factors associated with squamous cell carcinoma include overexposure to the sun's ultraviolet rays, radiation therapy, ingestion of herbicides containing arsenic, chronic skin irritation and inflammation, exposure to local carcinogens (such as tar and oil), hereditary diseases (such as xeroderma pigmentosum and albinism), and the presence of premalignant lesions (such as actinic keratosis or Bowen's disease). (family-health-information.com)
  • Purpose: We describe the efficacy of surgical excision of metastatic renal cell carcinoma of bone for achieving local tumor control, pain control and functional outcome with emphasis on the indications and techniques of surgical intervention as well as oncological outcome. (tau.ac.il)
  • By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
  • The first patient was a 61-year-old woman with colorectal carcinoma and liver metastasis, who underwent chemotherapy consisting of 6 cycles of oxaliplatin (the FOLFOX scheme, a chemotherapy regimen consisting of fluorouracil [5 FU], folinic acid, and oxaliplatin). (cdc.gov)
  • [ 4 , 5 ] ) Benign neoplasms occur more frequently in women than in men, but malignant tumors are distributed equally between the sexes. (medscape.com)
  • There was substantial agreement regarding the expression of HER2 in primary tumors and metastases, and ER at metastases, between local and central laboratories. (springer.com)
  • Bronchial carcinoid tumors are rare, accounting for up to 2.5% of all pulmonary neoplasms and for 12-15% of carcinoid tumors overall. (medscape.com)
  • Myxopapillary ependymomas are well differentiated low-grade tumors which have been documented to local or distant metastasis. (balkanmedicaljournal.org)
  • Імунодіагностика пухлин Tumor-associated antigens (TAAs) can help diagnose various tumors and sometimes determine the response to therapy or recurrence. (msdmanuals.com)
  • TYRP1 mRNA expression in melanoma metastases correlates with clinical outcome. (hal.science)
  • Our study aimed to determine in melanoma metastases a gene expression profile associated with patient survival, and to identify and validate marker(s) of poor clinical outcome. (hal.science)
  • METHODS: Skin and lymph node metastases from melanoma patients (training population) were used to identify candidate prognostic marker(s) based on DNA microarray analysis. (hal.science)
  • CONCLUSION: Our data indicate that TYRP1 mRNA expression level, at least in skin metastases, is a prognostic marker for melanoma, and is particularly useful when prognostic pathology parameters at the primary lesion are lacking. (hal.science)
  • This article reviews the literature that helps frame those guidelines, with specific focus on results from the MSLT-I, as this is currently the only randomized controlled trial comparing wide local excision (WLE) and SLNB with WLE and observation in the treatment of melanoma. (medscape.com)
  • Ten dogs were euthanised due to locoregional or distant progression of their mixed thyroid neoplasm. (oregonstate.edu)
  • The study also reported that recurrence risk factors for these lesions included positive and uncertain resection margins, as well as younger age at diagnosis. (medscape.com)
  • The goal of surgical excision is to achieve negative resection margins, thus reducing the local recurrence rate. (thieme-connect.de)
  • 19 ] [ 20 ] In one study investigating 16 cases of infiltrative lipomas, the median time to recurrence was 239 days, with 67% of dogs being disease-free at 1-year post-surgical resection. (thieme-connect.com)
  • Materials and methods: A total of 51 consecutive patients were treated for hepatic recurrence(s) after an initial partial hepatic resection. (prinsesmaximacentrum.nl)
  • Conclusions: Resection, RFA, and SRx can be performed safely in patients with recurrent colorectal liver metastases and offer a survival that seems comparable to primary liver resections of colorectal liver metastases. (prinsesmaximacentrum.nl)
  • She underwent tumor resection eight times due to the recurrence of spinal tumor in the same region in nine years. (balkanmedicaljournal.org)
  • Local recurrence developed in only 4 of the 56 lesions (7.1%), including 3 after marginal resection. (tau.ac.il)
  • In September 2003, a left colectomy, resection of metastasis in the left side of the liver, and a ligation of the right portal vein were performed. (cdc.gov)
  • Conclusion: Local recurrence after treatment of breast cancer with mastectomy+radiotherapy+/-systemic therapy is associated with a significantly higher risk of distant metastasis and death. (who.int)
  • Most series report that about 80% of parotid neoplasms are benign, with the relative proportion of malignancy increasing in the smaller glands. (medscape.com)
  • Gangliocytic Paraganglioma is a tumor originating in the hindgut, a rare neoplasm, generally affecting the second portion of the duodenum, the majority of which are benign. (biomedcentral.com)
  • We first expected the mass to be a benign hemangioma and performed an excisional biopsy under local anesthesia ( Fig. 1B ). (kjhno.org)
  • Lipomas are common benign neoplasms originating from subcutaneous tissue adipocytes, with no tendency to metastasize. (thieme-connect.com)
  • Endoscopic submucosal dissection (ESD) permits removal of esophageal epithelial neoplasms en bloc , but is associated with esophageal stenosis, particularly when ESD involves the entire circumference of the esophageal lumen. (biomedcentral.com)
  • An MRI at 12 months and 18-fluoro-deoxyglucose positron emission tomography of the brain at 13 months showed decreased edema with no signs of tumor recurrence. (surgicalneurologyint.com)
  • To date, 5 years after surgery, the patient remains without evidence of tumor recurrence. (mdpi.com)
  • The prognostic significance of bone marrow micro-metastases (BMM) in colon cancer patients remains unclear. (nih.gov)
  • Bone marrow micro-metastases occur in over one third of stage I-III colon cancer patients and are a significant, independent negative prognostic factor for DFS and OS. (nih.gov)
  • Primary tumor screening proved liver and mediastinal lymph node involvement as well as the presence of a solitary L3 bone metastasis (T4N3M1a). (surgicalneurologyint.com)
  • Osteosarcoma is a malignant bone neoplasm with aggressive clinical evolution which is usually diagnosed in late stages of the disease, when primary tumor reaches significant dimensions. (bvsalud.org)
  • Indications for surgery were solitary bone metastasis, intractable pain, or impending or present pathological fracture. (tau.ac.il)
  • The spine is the most frequent area of bone metastasis in patients with systemic neoplastic disease. (bvsalud.org)
  • This may be because for many years, it has been assumed that the biomarker status of the primary tumor and its corresponding metastasis was not different. (springer.com)
  • Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
  • EXPERIMENTAL DESIGN: One hundred colorectal cancer metastases were screened for mutations in 19 oncogenes, and further 61 metastases and 87 matched primary cancers were analyzed for genes with identified mutations. (ox.ac.uk)
  • Mutation prevalence was compared between (a) metastases from liver (n = 65), lung (n = 50), and brain (n = 46), (b) metastases and matched primary cancers, and (c) metastases and an independent cohort of primary cancers (n = 604). (ox.ac.uk)
  • Mutation status was highly concordant between primary cancer and metastasis from the same individual. (ox.ac.uk)
  • The most common malignant primary neoplasms are adenoid cystic and mucoepidermoid carcinomas. (oncologybuddies.com)
  • The primary treatment for DFSP is surgical excision, which is wide local excision (WLE) with tumor-free margins, Mohs micrographic surgery (MMS), and partial or total amputation. (thieme-connect.de)
  • Early pregnancy and early oophorectomy lower the incidence of breast neoplasm. (who.int)
  • Known risk factors include ultraviolet (UV) and ionizing radiation, a history of local trauma or burns, immunosuppression, and inherited conditions like xeroderma pigmentosa and Cowden disease. (jcadonline.com)
  • Additional skin metastases (validation population) were used to assess the prognostic value of the first ranked gene by real-time PCR. (hal.science)
  • PURPOSE: This study was designed to evaluate the results of local control, survival rate, prognostic factors, and failure pattern in locally advanced esophageal cancer. (whocc.org.cn)
  • 5-8 They can be locally aggressive and can exhibit telangiectasias and ulceration due to local destruction. (jcadonline.com)
  • Pathologic factors associated with a higher risk of recurrence (eg, size, lymph node involvement, pleural invasion) all increased the sex-specific hazard rates. (duke.edu)
  • Due to the high grade of these tumours, sometimes close or positive margins, and their propensity for perineural invasion, post-operative radiation is almost always indicated to achieve local control. (oncologybuddies.com)
  • Its prominent properties are A lack of cell differentiation Local invasion of adjoining tissue Metastasis, which is spread to distant sites through. (msdmanuals.com)
  • The patient deferred Mohs micrographic surgery in favor of wide local excision and was treated successfully with 3-mm margins. (jcadonline.com)
  • RESULTS: All 14 dogs had curative-intent surgery to remove the thyroid neoplasm. (oregonstate.edu)
  • SRx was given as an outpatient, emerging local treatment option for patients with intra-hepatic recurrences not eligible for surgery or RFA. (prinsesmaximacentrum.nl)
  • In which 6.5% (10 patients out of 152) in upfront surgery group and 15.2% (7 patients out of 46) in LABC group developed local recurrence. (who.int)
  • So, total 5% (10 patients) in upfront surgery group and 3.5% (7 patients) in LABC group out of 198 total patients developed local recurrence. (who.int)
  • 0.005), but similar in liver metastases. (ox.ac.uk)
  • Objective: The objective of the study was to identify patients who may benefit from local treatment in recurrent colorectal liver metastases. (prinsesmaximacentrum.nl)
  • Of further relevance is that this tumour is more commonly calcified than any other kidney neoplasm. (wikipedia.org)
  • Unlike most other cancers, where metastases from the site of origin is the main cause of death, GBM very rarely metastasizes outside the neuraxis. (frontiersin.org)
  • There was no significant relationship between the DNA ploidy status and histopathological grading, lymph node metastasis and local recurrence development, respectively. (researchgate.net)
  • The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
  • However, local recurrence or distant metastasis still occur in some patients even after radical nephrectomy. (biomedcentral.com)
  • Metastasis to other parts of the body can occur. (family-health-information.com)
  • Ten dogs developed metastatic disease with the most common metastatic site being the lungs (6/10 dogs), with a median time to metastasis of 93 days. (oregonstate.edu)
  • Although infiltrative lipomas are not uncommon, the clinical and surgical challenges they often present due to local functional damage and recurrence are infrequently described. (thieme-connect.com)
  • Under the diagnosis of uterine neoplasm, we carried out radical hysterectomy, omentectomy and pelvic lymphadenectomy as the surgical procedure. (balkanmedicaljournal.org)