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  • chromosomal
  • The aim of this study was to illustrate that the use of SNP-A can cover cryptic chromosomal lesions not identified by metaphase cytogenetics in patients with MDS. (ovid.com)
  • In our cohort of 15 patients with a diagnosis of MDS and related diseases, chromosomal abnormalities were found in 47% of the cases by SNP-A and in 33% by metaphase cytogenetics. (ovid.com)
  • SNP-A may complement metaphase cytogenetics to improve the detection of chromosomal abnormalities in myeloid neoplasms. (ovid.com)
  • cells
  • The BioDot technology can be used for both spotting of cells or metaphase chromosome preparations in nanoliter volumes for FISH and microscopic analysis. (prweb.com)
  • However, metaphase cytogenetics requires cellular proliferation, its sensitivity and resolution depends on the proportion of clonal cells in the sample and size of the lesion, respectively. (ovid.com)
  • microscopic
  • Although many auto-focusing methods have been developed and tested for a variety of imaging modalities, few investigations have been performed on the selection of an optimal auto-focusing method that is suitable for the pathological metaphase chromosome analysis under a high resolution scanning microscopic system. (hindawi.com)
  • clinical
  • Metaphase cytogenetics is an extremely valuable clinical tool in the management of haematological malignancies. (ovid.com)