• blastema
  • 3,4) From a pathophysiology standpoint, horseshoe kidney occurs during the second and sixth week of gestation when the inferior portion of the metanephric blastema fuses to form an isthmus, commonly in the lower renal pole (90%) and anteriorly to the aorta and vena cava. (thefreedictionary.com)
  • Defect
  • Gilbert T, Gaonach S, Moreau E, Merlet-BĂ©nichou C. Defect of nephrogenesis by gentamicin in rat metanephric organ culture. (springer.com)