AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsTechnology, Industry, AgricultureInformation ScienceHealth Care
Magnetic Resonance SpectroscopyMagnetic Resonance ImagingNuclear Magnetic Resonance, BiomolecularMagnetic Resonance AngiographyMagnetic Resonance Imaging, CineModels, MolecularProtein ConformationEnergy MetabolismCarbon IsotopesBrainPhosphocreatineProtonsMolecular ConformationSolutionsSurface Plasmon ResonancePhosphorusWaterContrast MediaLipid MetabolismHydrogen-Ion ConcentrationProteinsFluorineModels, ChemicalBiosensing TechniquesMolecular Sequence DataDeuteriumComputer SimulationProtein BindingKineticsAlgorithmsDiffusion Magnetic Resonance ImagingGadoliniumThermodynamicsGadolinium DTPAMass SpectrometryAmino Acid SequenceMolecular StructureMolecular Dynamics SimulationBinding SitesGlucoseProtein Structure, SecondarySolventsNitrogen IsotopesTime FactorsReproducibility of ResultsBrain MappingModels, BiologicalMetabolismHydrogenElectron Spin Resonance SpectroscopyPhosphatesChromatography, High Pressure LiquidSoftwareMetabolomicsBiopolymersImage Processing, Computer-AssistedSensitivity and SpecificityTemperatureFluorescence Resonance Energy TransferProtein Structure, TertiaryOxygenStatic ElectricityCircular DichroismImage Interpretation, Computer-AssistedChemistryPhosphorus IsotopesMetabolomeBiophysicsChemical PhenomenaLactic AcidImage EnhancementLiverPeptidesImaging, Three-DimensionalEscherichia coliProtein Interaction MappingAcetatesAdenosine TriphosphateOxidation-ReductionGlycolysisDiffusionSurface PropertiesCreatineCholineHydrogen BondingQuantum TheoryNanotechnologyMagnetic Resonance Imaging, InterventionalCarbohydrate SequenceTomography, X-Ray ComputedNucleic AcidsSpectrophotometry, InfraredDNAComputational BiologyBiological PhenomenaSpectrum Analysis, RamanAspartic AcidNucleic Acid ConformationPhosphorylcholineProtein Folding
SpectroscopyChemistryMass spectrometryDrug metabolismNeuronsOrganicSpectraMitochondrialImagingCerebralProcessesImmunityFacilityMetabolitesOverhauserExternal magnetic fieldSpinBiological systemsSynthesisStudySpinsExperimentsChemicalEnergyAnalyticalCENTERMedicineStudiesCarbonEffectsFieldWorkFieldsUniversityTechnology
Spectroscopy9
  • We recovered 13C-labelled metabolites by microdialysis and utilised nuclear magnetic resonance spectroscopy (NMR) for identification and quantification.Of 33 patients with complete monitoring, 73% had MD at some point during monitoring. (cam.ac.uk)
  • The group uses biomolecular NMR spectroscopy coupled to biochemical, biophysical and computational methods to study the structure/function activity of proteins (or protein domains) involved in human diseases (e.g. cancer, genetic diseases). (hsr.it)
  • In this study an untargeted 1H nuclear magnetic resonance spectroscopy-based metabolomic approach was used to compare the urinary, plasma, and fecal metabolic phenotypes of cats with CE to control cats with no gastrointestinal signs recruited at the Royal Veterinary College (RVC). (bvsalud.org)
  • Dr. Fariba Assadi-Porter is Senior Scientist and Principal Investigator in the Department of Zoology at the University of Wisconsin-Madison with over 20 years of research in biochemistry, NMR spectroscopy, and metabolism studies. (eurekaselect.com)
  • Next, Kurt Wüthrich - recipient of the 2002 Nobel Prize in Chemistry for the development of nuclear magnetic resonance (NMR) spectroscopy - made a brief statement about imaging macromolecules in solution, which are under the regime of Brownian motion. (lindau-nobel.org)
  • The tools available for such investigations include the state-of-the-art ultra-performance liquid chromatography mass spectrometry (UPLC-MS) and nuclear magnetic resonance (NMR) spectroscopy technologies. (scelse.sg)
  • NMR spectroscopy, the experimental process tied to NMR, produces valuable data by having atomic nuclei interact with a magnetic field. (nmr-nl.org)
  • NMR spectroscopy heavily relies on resonance. (nmr-nl.org)
  • NMR spectroscopy uses specific pulse sequences to manipulate nuclear spins and gather valuable information. (nmr-nl.org)
Chemistry3
  • She obtained her undergraduate degree in Chemistry and her Ph.D. in Biomolecular Chemistry at UW-Madison. (eurekaselect.com)
  • The combination of Parahydrogen Induced Polarization with long-lived spin-states and enzymatic conversion finally breaks the door to a cost-efficient magnetic resonance imaging of fumarate and similar tumor markers in cancer metabolism,' added Professor Gerd Buntkowsky, head of the Physical Chemistry of Condensed Matter group at TU Darmstadt and corresponding author of the work. (uni-mainz.de)
  • Organic and Biomolecular Chemistry, 8 (2). (lincoln.ac.uk)
Mass spectrometry2
  • Dave Watson BSc PhD PGCE is a reader in Pharmaceutical Sciences at the University of Strathclyde up He has specialised in chromatographic methods combined with mass spectrometry which he has applied to a range of problems ranging from drug metabolism and disposition through to metabolomics. (eurekaselect.com)
  • Some of these apparati are located on the ninth floor of MRB III, within the world-renowned Vanderbilt University School of Medicine Mass Spectrometry Research Center, and in Vanderbilt's two powerful Nuclear Magnetic Resonance facilities. (vanderbiltvanguard.com)
Drug metabolism1
  • Synthesis of plasmodione metabolites and 13C-enriched plasmodione as chemical tools for drug metabolism investigation. (mpg.de)
Neurons1
  • Magnetic resonance and optical imaging probes for NMDA receptors on the cell surface of neurons: synthesis and evaluation in cellulo. (mpg.de)
Organic2
  • Nuclear Magnetic Resonance, abbreviated as NMR, is a tool used by researchers to analyze the structure of organic compounds . (vanderbiltvanguard.com)
  • These interactions arise from the magnetic coupling between nuclei that have a spin, such as hydrogen atoms in organic molecules. (nmr-nl.org)
Spectra1
  • The signals observed in in vivo carbon-13 nuclear magnetic resonance (13C NMR) spectra are from 'mobile' molecules, i.e. those with relatively unrestricted motion. (westminster.ac.uk)
Mitochondrial1
  • Focally administered succinate improves cerebral metabolism in traumatic brain injury patients with mitochondrial dysfunction. (cam.ac.uk)
Imaging7
  • Magnetic Resonance Imaging. (elsevierpure.com)
  • Magnetic resonance imaging (MRI) is already widely used in medicine for diagnostic purposes. (uni-mainz.de)
  • Then we can use the associated magnetic signals for imaging,' Dr. James Eills pointed out. (uni-mainz.de)
  • Evaluation of crotamine based probes as intracellular targeted contrast agents for magnetic resonance imaging. (mpg.de)
  • Microscopic Visualization of Metabotropic Glutamate Receptors on the Surface of Living Cells Using Bifunctional Magnetic Resonance Imaging Probes. (mpg.de)
  • Dr.Ali S Arbab is a Physician Research Scientist with broad experience in imaging sciences and cell biology.His Research interest in Extensive clinical and pre-clinical experiences in nuclear medicine (nuclear cardiology, nuclear oncology, and cerebral perfusion), magnetic resonance imaging (MRI), X-ray computed tomography (CT), ultrasonography and molecular imaging. (omicsonline.org)
  • Additionally, NMR techniques are being used extensively in the medical industry, where magnetic resonance imaging (MRI) enables healthcare professionals to obtain accurate and detailed images of the human body, facilitating diagnosis and further research. (nmr-nl.org)
Cerebral1
Processes2
  • In this 6-week course, students will learn thermodynamics of various biomolecular processes, including conformational changes, molecular association / dissociation, and protein-drug interactions. (utmb.edu)
  • MRI images can show us the structure of the brain, for example, but they tell us nothing about the biomolecular processes occurring in the body, partly because of the poor sensitivity of MRI,' said Dr. James Eills, first author of the study and member of the work group led by Professor Dmitry Budker at JGU and HIM. (uni-mainz.de)
Immunity1
  • Both chronic and acute forms of child undernutrition are characterized by derangements in multiple biological systems including metabolism, immunity, and endocrine systems. (bvsalud.org)
Facility1
  • Unbeknownst to most, Vanderbilt also houses two Nuclear Magnetic Resonance facilities (Small Molecule NMR Core Facility and Biomolecular Facility) which aggregate to form one of, if not the most, powerful Nuclear Magnetic Resonance centers in the country. (vanderbiltvanguard.com)
Metabolites1
  • Here, plasma metabolites related to energy and amino acid metabolism significantly varied between CE and control cats in the RVC cohort. (bvsalud.org)
Overhauser1
  • The effects of nitroxide structure upon 1H Overhauser dynamic nuclear polarization efficacy at ultralow-field. (mpg.de)
External magnetic field2
  • This achieves significant alignment of the signal-generating nuclear spins with the help of an external magnetic field. (uni-mainz.de)
  • When exposed to an external magnetic field, these nuclei rotate and align either parallel (low energy state) or anti-parallel (high energy state) to the field. (nmr-nl.org)
Spin2
  • The foundation of NMR lies in nuclear spin. (nmr-nl.org)
  • Nuclei with an odd number of protons or neutrons have a unique property called spin that generates an extremely small magnetic moment. (nmr-nl.org)
Biological systems1
  • The lab's model qubit is the Nitrogen-Vacancy center in diamond, which they use to image magnetic phenomena in condensed-matter and biological systems over a broad range of length scales. (nih.gov)
Synthesis1
  • In addition the course presents the general principles of regulation in metabolism, molecular signaling and synthesis and function of different biomolecules as they apply to developing an understanding of regulatory mechanisms in homeostasis and disease. (utmb.edu)
Study1
  • In the study under discussion, the scientists describe their technique for singlet-contrast MRI using fumarate, a biomolecule naturally occuring as an intermediate product of metabolism. (uni-mainz.de)
Spins1
  • The use of a radiofrequency pulse mecanism stimulates nuclear spins, causing them to transition from a low to a high energy state. (nmr-nl.org)
Experiments2
  • Nuclear magnetic resonance (NMR) experiments combined with size exclusion and analytical ultracentrifugation measurements confirm these observations and reveal BteA287 to be monomeric in nature with a tendency to oligomerize at concentrations above 200 µM. (nih.gov)
  • MagLab researchers understand how high magnetic fields lead to big discoveries, whether it's our robust in-house research teams or the more than one-thousand visiting scientists who conduct experiments here annually. (nationalmaglab.org)
Chemical1
Energy3
  • In these, focal succinate administration improved energy metabolism, evidenced by reduction in LPR. (cam.ac.uk)
  • These two directions have a distinct gap in energy, which are perceived by the machine after a magnetic pulse briefly synchronizes the atoms. (vanderbiltvanguard.com)
  • The magnet generates a robust, uniform magnetic field while the RF transmitter emits radiofrequency energy pulses. (nmr-nl.org)
Analytical1
  • NMR, or Nuclear Magnetic Resonance, is a trusted analytical method that uses the natural magnetic properties of atomic nuclei. (nmr-nl.org)
CENTER1
  • Lisa Warner, an assistant research professor with Boise State's Biomolecular Research Center, is fascinated by the metabolic pathways found in living systems. (boisestate.edu)
Medicine1
Studies1
  • Deuteron nuclear magnetic resonance and dielectric studies of molecular reorientation and charge transport in succinonitrile-glutaronitrile plastic crystals. (mpg.de)
Carbon1
Effects1
Field4
  • These fragments are then deflected by a magnetic field to varying degrees, depending on their mass-to-charge ratio. (vanderbiltvanguard.com)
  • His lecture traced the history of the field from five years before his involvement to the present era, where cryo-EM is regarded as a highly revolutionary technique for the generation of 3D images of biomolecular structures at near-atomic resolution. (lindau-nobel.org)
  • LIGHT-SABRE Hyperpolarizes 1-13C-Pyruvate Continuously without Magnetic Field Cycling. (mpg.de)
  • Complete magnetic field dependence of SABRE-derived polarization. (mpg.de)
Work2
  • This led to great success, such as the work of Gertrude Elion and George H. Hitchings on purine metabolism, the work of James Black on beta blockers and cimetidine, and the discovery of statins by Akira Endo. (wikipedia.org)
  • Demystifying Nuclear Magnetic Resonance: How Does it Work? (nmr-nl.org)
Fields3
  • Want to use high magnetic fields to elevate your research? (nationalmaglab.org)
  • Hyperpolarization of cis-15N,15N'-azobenzene by parahydrogen at ultralow magnetic fields. (mpg.de)
  • Nuclear magnetic resonance (NMR) has become increasingly valuable in a variety of fields, thanks to its capacity to provide significant insights. (nmr-nl.org)
University1
  • In addition, the biomolecular consequences of a hydrolyzed protein diet in cats with CE was also separately determined in cats recruited from the RVC (n = 16) and the University of Bristol (n = 24) and whether these responses differed between dietary responders and non-responders. (bvsalud.org)
Technology1
  • Discover the allure of Nuclear Magnetic Resonance (NMR) technology and unravel its complex mechanisms with this comprehensive article. (nmr-nl.org)