Metabolism in human liver microsomes. Medical search. Frequent questions

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Anatomy12

Microsomes, Liver Microsomes Liver Hepatocytes Mitochondria, Liver Intestines Bile Cytosol Cells, Cultured Kidney Cell Line Subcellular Fractions

Organisms12

Rats, Inbred Strains Rats, Sprague-Dawley Insects Rats, Gunn Dogs Rats, Wistar Rabbits Rats, Inbred F344 Baculoviridae Euphorbia Haplorhini Macaca fascicularis

Diseases11

Liver Diseases Liver Neoplasms Liver Cirrhosis Fatty Liver Drug-Induced Liver Injury Liver Neoplasms, Experimental Carcinoma, Hepatocellular Liver Failure, Acute Liver Diseases, Alcoholic Crigler-Najjar Syndrome Liver Abscess

Chemicals and Drugs159

Cytochrome P-450 Enzyme System Cytochrome P-450 CYP3A Aryl Hydrocarbon Hydroxylases Glucuronides Mixed Function Oxygenases Glucuronosyltransferase Oxidoreductases, N-Demethylating Steroid 16-alpha-Hydroxylase Troleandomycin Ketoconazole Cytochrome P-450 CYP1A2 Cytochrome P-450 CYP2D6 Sulfaphenazole Isoenzymes Uridine Diphosphate Glucuronic Acid Phenacetin Steroid Hydroxylases Mephenytoin Orphenadrine Enzyme Inhibitors Quinidine NADP Cytochrome P-450 CYP2E1 Recombinant Proteins Benzoflavones Oxidoreductases, O-Demethylating Coumarins Chlorzoxazone Sapogenins Glucuronates NADPH-Ferrihemoprotein Reductase Proadifen Oxygenases Midazolam Tolbutamide Mephobarbital Phenobarbital Fluvoxamine Ticrynafen Diclofenac Dextromethorphan Cytochromes b5 Hydroxytestosterones Triazolam 7-Alkoxycoumarin O-Dealkylase Safrole Dextrorphan Nitrosamines Alamethicin Gemfibrozil Debrisoquin Perhexiline Endosulfan Aldrin Pharmaceutical Preparations Methylcholanthrene Glucuronic Acid Prodrugs Glutathione Methadyl Acetate Phenytoin Carboxylic Ester Hydrolases Bupropion Butyrophenones Benzydamine Carboxylesterase Cytochrome P-450 CYP1A1 Imipramine Amitriptyline Cytochrome-B(5) Reductase Tranylcypromine Propiophenones DNA, Complementary Acetonitriles Methoxychlor Sulfoxides Monoterpenes Sparteine Oxidoreductases Triazoles Menthol Fenbendazole Carbon Radioisotopes Epoxy Compounds Flutamide Dimethylnitrosamine beta-Naphthoflavone Carcinogens Nortriptyline Liver Extracts Designer Drugs Catechols Ethanolamines Glucose Testosterone Cytochrome Reductases Triacetoneamine-N-Oxyl RNA, Messenger Benzopyrenes Astemizole Mefenamic Acid Acetaminophen Bilirubin Theophylline Carbamazepine Terfenadine Bile Acids and Salts Histamine H1 Antagonists Glucose-6-Phosphatase Fatty Acids Antibodies Terpenes Oxazines Mexiletine Miocamycin Hymecromone Phenothiazines Ditiocarb Trifluoperazine Pyridines Flavonoids Anti-Allergic Agents Dextropropoxyphene Monoamine Oxidase Proguanil Sertraline Cotinine Benzopyrene Hydroxylase Cimetidine Paroxetine Epoxide Hydrolases Cresols Isoxazoles Fluoxetine 1-Propanol Antidepressive Agents, Second-Generation Lignans Serotonin Uptake Inhibitors Antidepressive Agents, Tricyclic Cetomacrogol Cytochrome P-450 CYP2B1 Medetomidine Phenols Benzphetamine Quinolines Plant Extracts Flurbiprofen Omeprazole Indenes Imidazoles Phthalazines Flavanones Sulfinpyrazone Warfarin Zidovudine Chrysenes Aflatoxin B1 Anticonvulsants Cholesterol

Analytical, Diagnostic and Therapeutic Techniques and Equipment20

Chromatography, High Pressure Liquid Liver Transplantation Mass Spectrometry Chromatography, Liquid Tandem Mass Spectrometry Gas Chromatography-Mass Spectrometry Spectrophotometry, Ultraviolet Magnetic Resonance Spectroscopy Spectrometry, Mass, Electrospray Ionization Liver Function Tests Metabolic Clearance Rate Liver Neoplasms, Experimental Area Under Curve Models, Biological Inhibitory Concentration 50 Blotting, Western Drug Evaluation, Preclinical Administration, Oral Drug Stability Chromatography, Thin Layer

Phenomena and Processes39

Hydroxylation Biotransformation Dealkylation Kinetics Metabolic Detoxication, Phase I Drug Interactions Stereoisomerism Oxidation-Reduction Substrate Specificity Molecular Structure Metabolic Detoxication, Phase II Lipid Metabolism Metabolic Detoxication, Drug Liver Regeneration Energy Metabolism Species Specificity Catalysis Enzyme Induction Dose-Response Relationship, Drug Metabolic Clearance Rate Methylation Half-Life Area Under Curve Herb-Drug Interactions Time Factors Hydrolysis Amino Acid Sequence Hydrogen-Ion Concentration Metabolism Alkylation Liver Circulation Food-Drug Interactions Structure-Activity Relationship Base Sequence Inhibitory Concentration 50 Tissue Distribution Polymorphism, Genetic Protein Binding Isomerism

Disciplines and Occupations1

Immunochemistry

Technology, Industry, Agriculture1

Information Science3

Molecular Sequence Data Amino Acid Sequence Base Sequence

Health Care1

Area Under Curve

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science Health Care

Microsomes, Liver Cytochrome P-450 Enzyme System Microsomes Cytochrome P-450 CYP3A Hydroxylation Biotransformation Aryl Hydrocarbon Hydroxylases Glucuronides Dealkylation Mixed Function Oxygenases Glucuronosyltransferase Oxidoreductases, N-Demethylating Steroid 16-alpha-Hydroxylase Troleandomycin Liver Ketoconazole Cytochrome P-450 CYP1A2 Cytochrome P-450 CYP2D6 Chromatography, High Pressure Liquid Sulfaphenazole Isoenzymes Uridine Diphosphate Glucuronic Acid Phenacetin Kinetics Steroid Hydroxylases Metabolic Detoxication, Phase I Mephenytoin Drug Interactions Orphenadrine Stereoisomerism Enzyme Inhibitors Liver Diseases Oxidation-Reduction Quinidine NADP Cytochrome P-450 CYP2E1 Recombinant Proteins Liver Neoplasms Benzoflavones Hepatocytes Oxidoreductases, O-Demethylating Coumarins Chlorzoxazone Liver Transplantation Sapogenins Mass Spectrometry Glucuronates NADPH-Ferrihemoprotein Reductase Proadifen Chromatography, Liquid Substrate Specificity Tandem Mass Spectrometry Liver Cirrhosis Oxygenases Midazolam Molecular Structure Tolbutamide Mephobarbital Metabolic Detoxication, Phase II Phenobarbital Fluvoxamine Lipid Metabolism Ticrynafen Diclofenac Metabolic Detoxication, Drug Dextromethorphan Liver Regeneration Rats, Inbred Strains Cytochromes b5 Fatty Liver Hydroxytestosterones Energy Metabolism Species Specificity Rats, Sprague-Dawley Triazolam Catalysis 7-Alkoxycoumarin O-Dealkylase Mitochondria, Liver Gas Chromatography-Mass Spectrometry Safrole Dextrorphan Spectrophotometry, Ultraviolet Nitrosamines Alamethicin Enzyme Induction Gemfibrozil Debrisoquin Perhexiline Endosulfan Dose-Response Relationship, Drug Magnetic Resonance Spectroscopy Aldrin Pharmaceutical Preparations Methylcholanthrene Glucuronic Acid Insects Rats, Gunn Dogs Prodrugs Glutathione

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