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  • adipose tissue
  • The abundance levels of proteins known to be responsive to nutrient levels such as aldolase and fatty acid binding proteins, as well as the expression levels of FASN, a key lipogenic enzyme, and MLXIPL , a pivotal transcriptional mediator of glucose-related stimulation of lipogenic genes, were elevated in the adipose tissue of pure and crossbred fetuses from Meishan sows. (springer.com)
  • Time-course differences in adipose tissue protein abundance were revealed between fetal genotypes for a few secreted proteins participating in responses to organic substances, such as alpha-2-HS-glycoprotein, transferrin and albumin. (springer.com)
  • These results underline the importance of not only fetal age but also maternal intrauterine environment in the regulation of several proteins in subcutaneous adipose tissue. (springer.com)
  • We have shown that protein malnutrition during fetal growth followed by postnatal high-fat diets results in a rapid increase in subcutaneous adipose tissue mass in the offspring contributing to development of obesity and insulin resistance. (usda.gov)
  • These finding suggest that high-fat diet fed offspring from mothers that consumed a low-protein diet have reduced induction of beige adipocytes in subcutaneous adipose tissue and that this may be part of the mechanism by which maternal protein malnutrition may cause offspring obesity and metabolic alterations. (usda.gov)
  • enzymes
  • Recent studies have revealed that biological functions of several membrane transporters and enzymes (tissue nonspecific alkaline phosphatase, ENPP1, PHOSPHO1 and ANK, etc.) equipped in the matrix vesicles, as well as non-collagenous proteins, are coordinated to enable the spatiotemporal crystallization of calcium phosphate (hydroxyapatite). (springer.com)
  • Programming of hepatic insulin-sensitive enzymes in offspring of rat dams fed a protein-restricted diet. (semanticscholar.org)
  • malnutrition
  • Methodology/Principal Findings: We reviewed the records of all children admitted with severe acute malnutrition to the Tropical Metabolism Research Unit Ward of the University Hospital of the West Indies, Kingston, Jamaica during 1962-1992. (scribd.com)
  • mother's
  • We found that a protein within lung surfactant serves as a hormone of labor that signals to the mother's uterus when the fetal lungs are sufficiently mature to withstand the critical transition to air breathing," Dr. Mendelson said. (bio-medicine.org)
  • differences
  • However, no fundamental explanation exists for these differences in metabolism, nor clinical pictures, given similar exposures to undernutrition. (scribd.com)
  • There were no significant differences in the uterine and fetal weight compared to control. (biomedsearch.com)
  • hormones
  • Liver is the main metabolizing organ in the body [ 1 ] and displays main digestive function for the metabolism of substances such as carbohydrates, fats, proteins, vitamins, and hormones. (omicsonline.org)
  • Lung
  • The research, which has implications for humans, marks the first time a link between a specific fetal lung protein and labor has been identified, said Dr. Carole Mendelson, professor of biochemistry and obstetrics and gynecology and senior author of the study. (bio-medicine.org)
  • There may be several chemical pathways that lead to labor, but we think that this surfactant protein, which is also produced by the fetal lung in humans, may be the first hormonal signal for labor," said Dr. Mendelson, who is co-director of the North Texas March of Dimes Birth Defects Center at UT Southwestern. (bio-medicine.org)
  • postnatal
  • However, the postnatal low-protein offspring had enzyme activities comparable with those of controls. (semanticscholar.org)
  • Using a rat model, we found that a maternal low protein followed by postnatal high fat diet results in increased offspring obesity and subcutaneous fat tissue weight possibly due to decreased beige color adipocyte numbers and beige color adipocyte's fat metabolizing capacity caused by reduced numbers of mitochondria. (usda.gov)
  • These results indicate that a maternal low protein and postnatal high fat diets increase the risk for offspring obesity and risk for type 2 diabetes by reduced fat metabolism in the subcutaneous fat tissue by decreased beige color fat cells. (usda.gov)
  • premature
  • ref7) A study published in February 2008 in 'Nicotine and Tobacco Research' found that factors from smoke can also raise the risk of spontaneous abortion or premature birth, and might also cause fetal neurological problems. (livestrong.com)
  • cardiac
  • Under cardiac hypertrophic conditions AKAP13 anchored PKD1 activates the transcription factor MEF2 leading to subsequent fetal gene activation and hypertrophic response. (paperity.org)
  • growth factors
  • Profiling the Sulfation Specificities of Glycosaminoglycan Interactions with Growth Factors and Chemotactic Proteins Using Microarrays (2007) Shipp Eric L et al. (naver.com)
  • tissue
  • still have significant tissue reserves of protein and fat, as these stores are mobilized inadequately during the disease process . (scribd.com)
  • mortality
  • previous attempts to improve fetal outcomes with use of maternal high-protein supplementation have actually increased the risk for small-for-gestational-age birth and infant mortality ( 26 , 36 ). (physiology.org)
  • Following oral administration of 1 g/kg body weight of water extracts but not methanolic extracts, fetal resorptions were significantly increased and mortality of postimplantation was increased. (biomedsearch.com)
  • IGF2
  • Minqi Li's research team ( 2018a ) reports that IGF2 messenger RNA-binding proteins (IMPs)-a family of onco-fetal RNA-binding proteins that play an important role in cell migration, renewal and metabolism, is involved in bone remodeling by regulating the activity of osteoclasts and impairing their adhesion. (springer.com)