AXY8 encodes an alpha-fucosidase, underscoring the importance of apoplastic metabolism on the fine structure of Arabidopsis cell wall polysaccharides. (mpg.de)
Transport and metabolism1
Alpha-L-fucosidase [Carbohydrate transport and metabolism]. (unl.edu)
Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues. (beds.ac.uk)
Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (unl.edu)
Furthermore, unlike other inborn errors of metabolism, unfortunately enzyme replacement therapy and substrate inhibition are not yet (as of March 2019) available 1 . (radiopaedia.org)
An enzyme that hydrolyzes 1,6-alpha-glucosidic branch linkages in glycogen, amylopectin, and their beta-limit dextrins. (nih.gov)
Encodes1
This gene encodes for alpha-L-fucosidase, which normally catalyzes the breakdown of various fucose-containing oligosaccharides, glycoproteins, and glycolipids 1,2,5 . (radiopaedia.org)
Galactose2
Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood. (lookformedical.com)
N-acetyl-D-galactosamine 6-phosphate is a galactosamine phosphate that involved in galactose metabolism and phosphotransferase system (PTS). (medchemexpress.com)
Subsp2
A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. (unl.edu)
A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. (unl.edu)
Inhibition1
That are initially dis cussed drug, has active metabolites, so, inhibition of hepatic metabolism using the has bled score. (hybridnutrition.co.za)
Fucose1
Alpha-L-fucosidase is responsible for cutting (cleaving) off a sugar molecule called fucose toward the end of the breakdown process. (medlineplus.gov)
History1
This type of diabetes is associated with older age, obesity, family history of diabetes, history of gestational diabetes, impaired glucose metabolism, physical inactivity, and race/ethnicity. (gotomydoctor.com)
Deficiency1
Dietary restriction has shown promise for disorders such as lysosomal acid lipase deficiency (Wolman disease), as has incorporation of lipid-lowering drugs in the regimen along with sebelipase alpha, a recombinant enzyme replacement therapy. (medscape.com)
Carbohydrate Metabolism1
Overall, analysis of transcriptomes and correlation networks indicates both bacterial species-specific responses to BBR, as well as functional commonalities among species, such as up-regulation of Na + /H + antiporter, cell wall synthesis/repair, carbohydrate metabolism and amino acid metabolism. (researchsquare.com)
Fucose2
An enzyme that catalyzes the hydrolysis of an alpha L-fucoside to yield an alcohol and L-fucose. (bvsalud.org)
Alpha-L-fucosidase is responsible for cutting (cleaving) off a sugar molecule called fucose toward the end of the breakdown process. (medlineplus.gov)
FUCA14
The aim of this work was to extend the knowledge about tissue alpha-L-fucosidase in colorectal cancer by quantifying the expression of its encoding gene FUCA1 in tumors and healthy mucosa. (nih.gov)
Our results demonstrated diminished FUCA1 mRNA levels in tumors, suggesting that expression of tissue alpha-L-fucosidase could be regulated at transcriptional level in colorectal cancer. (nih.gov)
Pathways of glycosphingolipid metabolism in both nervous tissue and visceral organs are elucidated, and for each catabolic step, a genetically determined metabolic derangement is identified. (medscape.com)
Enzymes1
Advances in understanding the molecular and biochemical basis include cloning and characterization of most genes that encode specific enzymes required for sphingolipid metabolism. (medscape.com)
Disorders1
Various disorders of lipid metabolism have characteristic patterns of organ involvement and clinical history, depending on the particular substrate that is stored. (medscape.com)
Bacterial1
First, we will learn how to estimate metabolism for a single bacterial isolate, starting from its genome sequence and ending with a file of metabolic module completeness scores. (anvio.org)
Hydrolysis1
Glycoside hydrolases that catalyze the hydrolysis of alpha or beta linked MANNOSE . (nih.gov)
Activity2
In previous studies we described a decreased alpha-L-fucosidase activity in colorectal tumors, appearing as a prognostic factor of tumoral recurrence. (nih.gov)
In addition, activity and expression of alpha-L-fucosidase in selected matched tumor and healthy mucosa samples were analyzed. (nih.gov)
AXY8 encodes an alpha-fucosidase, underscoring the importance of apoplastic metabolism on the fine structure of Arabidopsis cell wall polysaccharides. (mpg.de)
Sugar1
Other genes identified by the macroarray experiment included those associated with egg fertilization and development, sugar metabolism, apoptosis, and electron transport. (nih.gov)
Work1
Now you have a contigs database for this genome, so we can start to work with it to estimate metabolism. (anvio.org)
Beta1
Significant alterations in network topology and connectivity in function were observed, despite similarity in gut microbial alpha diversity ( P = 0.30) and beta-diversity ( P = 0.123) between control and BBR treatment. (researchsquare.com)