Metabolic features. Medical search. Frequent questions

Metabolic syndrome and hypoglycemia are two of the most common disorders that occur in about 20 to 30% of the population particularly in industrialized countries. (selfgrowth.com)
Metabolic disorders typically result when an enzyme necessary for some step in a metabolic process is missing or improperly constructed due to a genetic defect. (newworldencyclopedia.org)
Given the number of metabolic disorders and the range of systems affected, these disorders are manifested in a wide array of symptoms of varying severity, ranging from recurrent vomiting, lethargy, and muscle weakness, to liver and heart failure, developmental delay, and mental retardation. (newworldencyclopedia.org)
Most metabolic disorders are inherited from one or both parents who carry a defective gene that regulates a particular protein in a class of the body's cells. (newworldencyclopedia.org)
Imbalances in lipid metabolism are profound features of metabolic disorders. (nih.gov)
These genetic disorders are caused by deficiencies of certain metabolic enzymes that lead to buildup of life-threatening toxins. (hemoshear.com)
Our working hypothesis was that by undertaking comprehensive examination of metabolic profiles, in addition to traditional metabolic markers, it could be possible to elucidate the associations of circulating metabolites during pregnancy to postpartum metabolic disorders and thus to reveal potential targets for interventions. (springer.com)
Biochemical genetic testing and newborn screening are essential laboratory services for the screening, detection, diagnosis, and monitoring of inborn errors of metabolism or inherited metabolic disorders. (cdc.gov)
These recommendations are intended for laboratories that perform biochemical genetic testing to improve the quality of laboratory services and for newborn screening laboratories to ensure the quality of laboratory practices for inherited metabolic disorders. (cdc.gov)
Each lysosomal storage disorder is associated with a defined enzymatic deficiency, although as a group, these disorders share many clinical features. (medscape.com)
A positive family history of metabolic disorders. (who.int)

While SGFE were found to control other metabolic pathways such as Phenylalanine metabolism, Sphingolipid metabolism, Glycerollipid metabolism, Glycine, serine and threonine metabolism and Arginine and proline metabolism. (physiciansweekly.com)
The usual methods to model metabolic pathways are chemical descriptions and differential equations. (aaai.org)
Transcriptional regulation of the genes in metabolic pathways is a highly successful strategy, which is virtually universal in microorganisms. (lu.se)
When a second nutrient and its metabolic pathway are introduced, the system must further decide whether and how to activate both pathways. (lu.se)
Citation: Troein C, Ahre´n D, Krogh M, Peterson C (2007) Is Transcriptional Regulation of Metabolic Pathways an Optimal Strategy for Fitness? (lu.se)
A number of studies have explored how regulation of generally, and at least to a first approximation, it is obvious that metabolic pathways affects the growth rate of microorganisms, gene regulation only is useful if the environmental conditions vary both in the steady state and in response to changes in the local with time. (lu.se)
SIRT1 is increased in affected brain regions and hypothalamic metabolic pathways are altered in Huntington disease. (lu.se)

13 However, this conclusion has been criticized since the authors measured only four of the five features of the metabolic syndrome, and the cut-offs used for defining hypertension, dyslipidemia, and insulin resistance were different from those commonly proposed for diagnosis of this entity. (acc.org)
Several factors related to PCOS, including insulin resistance, metabolic syndrome, and obesity, increase a woman's risk of cardiovascular disease. (nih.gov)

Metabolic syndrome is a group of conditions which include elevated blood pressure, increased level of insulin, having excessive fat at the waist area and cholesterol levels that are beyond normal that result in diabetes and heart diseases. (selfgrowth.com)
When you are diagnosed to have metabolic syndrome, treatment should be done immediately so that your risk for developing other serious diseases will be avoided. (selfgrowth.com)
Dr. Delgado also outlines the role of hormones in diseases, and their effects in obesity, Metabolic Syndrome (pre-diabetes), and diabetes. (healthradio.net)
In vivo and in vitro studies have shown that extracts of different pomegranate fractions (peels, flowers, juice, and seeds) regulate lipid metabolism in metabolic-disorder-associated diseases such as atherosclerosis, nonalcoholic fatty liver disease, and type 2 diabetes, helping to alleviate the development of diseases. (nih.gov)
This review summarizes the main findings about the effects of different pomegranate fraction extracts on lipid metabolism in metabolic-disorder-associated diseases and analyses how pomegranate extracts achieve their effects. (nih.gov)
In the past few decades, metabolic diseases have emerged as some of the most significant public health problems worldwide. (biomedcentral.com)
Obesity, fatty liver, and diabetes are now among the most prevalent metabolic diseases across all age groups. (biomedcentral.com)
Obesity has reached epidemic proportions in many countries around the world and is closely associated with several chronic diseases, including metabolic disease. (biomedcentral.com)
As the number of inherited metabolic diseases that are included in state-based newborn screening programs continues to increase, ensuring the quality of performance and delivery of testing services remains a continuous challenge not only for public health laboratories and other newborn screening facilities but also for biochemical genetic testing laboratories. (cdc.gov)
The recommended practices address the benefits of using a quality management system approach, factors to consider before introducing new tests, establishment and verification of test performance specifications, the total laboratory testing process (which consists of the preanalytic, analytic, and postanalytic phases), confidentiality of patient information and test results, and personnel qualifications and responsibilities for laboratory testing for inherited metabolic diseases. (cdc.gov)

Diabetes, prediabetes and metabolic syndrom is a non-profite organisation with activities in healthy lifestyle, educational, youth, environmental and social activities. (bulmedica.bg)
Random Forests classifiers, based on the metabolic profiles, were used to predict the prediabetes status, and correlations of the metabolites to glycemic traits (fasting glucose and insulin, HOMA2-IR and HbA1c) and hsCRP at postpartum were evaluated. (springer.com)
We wanted to investigate the associations of early and late pregnancy serum metabolic profiles to the prediabetes status at two years' postpartum in an at-risk cohort of women who had overweight before becoming pregnant. (springer.com)

For a long time, Siraitia grosvenorii fruit extract (SGFE) and its dominant compounds, mogroside V(MV) were both reported to have therapeutic effects on allergic pneumonia, while previous studies only stay on phenotype and mechanism of the two active ingredients, hardly have any studies compared the two ingredients on the effect of liver metabolic, and revealed the relationship between mechanism and liver metabolism. (physiciansweekly.com)
Using the core principles of the successful The Metabolic Clock healthy life plan, The Metabolic Clock Cookbook is filled with recipes that are designed to speed up your metabolism and improve your health. (redwheelweiser.com)
The chemical signature that we discovered is evidence that CFS is an objective metabolic disorder that affects mitochondrial energy metabolism, immune function, GI function, the microbiome, the autonomic nervous system, neuroendocrine, and other brain functions. (omf.ngo)
Using comprehensive metabolomic analysis, we demonstrate unexpected metabolic differences in fatty acid metabolism between mutant IDH1 and IDH2 in patient samples with targetable metabolic interventions. (lu.se)

At the UCLA Center for Obesity and METabolic (COMET) Health, we offer the expertise, support and education you need to get you back on the road to health. (uclahealth.org)
The aim of this study was to evaluate the relative impact of obesity and metabolic syndrome (MS) on kidney disease. (karger.com)

Being extra careful with your health is all worth it, especially if you want to avoid having metabolic syndrome or hypoglycemia symptoms. (selfgrowth.com)
Having metabolic syndrome increases a person's risk for heart disease, stroke and diabetes. (lesliebeck.com)

Our knowledgeable experts treat obesity and fatty liver disease while improving metabolic health. (uclahealth.org)

Does a diagnosis of the metabolic syndrome provide additional prediction of cardiovascular disease and total mortality in the elderly? (mja.com.au)
To assess whether a diagnosis of the metabolic syndrome (MetS) improves the prediction of cardiovascular disease or total mortality beyond that already provided by conventional risk factors. (mja.com.au)
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. (mja.com.au)
The metabolic syndrome and mortality from cardiovascular disease and all-causes: findings from the National Health and Nutrition Examination Survey II Mortality Study. (mja.com.au)
ABSTRACT There is accumulating evidence suggesting that inflammation is the bridging link between cardiovascular disease and metabolic syndrome. (who.int)

Epidemiological, endocrine and metabolic features in Turner Syndrome. (bvsalud.org)

The serum metabolic profile during pregnancy might be used to identify women at increased risk for type 2 diabetes. (springer.com)
Too much glucose and insulin in the blood can lead to serious health conditions, including metabolic syndrome and type 2 diabetes. (nih.gov)
[ 12 ] Of note, the metabolic phenotype might be determined by the antibody titer in that patients with a high GAD antibody titer are phenotypically closer to type 1 diabetes with lower body mass index (BMI), whereas those with a low GAD antibody titer resemble patients with type 2 diabetes. (medscape.com)

1.46 mmol/L). Causes include chronic kidney disease, hypoparathyroidism, and metabolic or respiratory acidosis. (msdmanuals.com)
Metabolic acidosis is a clinical disturbance characterized by an increase in plasma acidity. (medscape.com)
Metabolic acidosis should be considered a sign of an underlying disease process. (medscape.com)
Go to Pediatric Metabolic Acidosis and Emergent Management of Metabolic Acidosis for complete information on those topics. (medscape.com)
3) Metabolic acidosis with an increase in the anion gap. (who.int)

Late onset of a metabolic disease is often triggered by acute metabolic stresses, such as infection, fasting, or consumption of a nutrient for which a metabolic intolerance exists. (newworldencyclopedia.org)
Main criteria (symptoms): 1) Sudden deterioration in the clinical condition of the child after a period of normal development (days, weeks, months): acute metabolic encephalopathy, lethargy (coma), seizures resistant to antiepileptic therapy. (who.int)

Hypoglycemia Symptoms and Metabolic Syndrome . (selfgrowth.com)

Clinical value of the metabolic syndrome for long term prediction of total and cardiovascular mortality: prospective, population based cohort study. (mja.com.au)

In this study, we have investigated the cord blood metabolic signatures of rapid growth in infancy and overweight in early childhood in four European birth cohorts. (nature.com)
This research seeks to examine the association between estimated dietary BCAA consumption and glycemic, and metabolic markers, as well as anthropometric parameters in adults classified as overweight or obese. (biomedcentral.com)
It has previously been demonstrated, in a cohort of women with overweight, that the serum metabolic profile of women developing GDM differs from those who remain normoglycemic already in early pregnancy (Mokkala et al. (springer.com)
Association of glomerular hyperfiltration with serum chemokine levels and metabolic features in prepubertal children with overweight/obesity. (bvsalud.org)
Chemokine associations with glomerular filtration rate (GFR) and metabolic features in prepubertal children with overweight (OW)/OB are unknown. (bvsalud.org)

Thus several computational genomics tools have been developed to predict metabolic gene clusters. (wikipedia.org)
Biomarkers of inflammation and of metabolic syndrome predict loss of lung function in World Trade Center (WTC) lung injury (LI). (cdc.gov)

They also found that OSAS led to systemic inflammation and metabolic syndrome. (acc.org)
Innate immunity and inflammation are regulated by the metabolic features of the CDR. (omf.ngo)

Metabolic gene clusters are also involved in nutrient acquisition, toxin degradation, antimicrobial resistance, and vitamin biosynthesis. (wikipedia.org)
A metabolic disorder is any disease or disorder that negatively affects the biochemical reactions through which individual animal cells process nutrient molecules (such as the components of carbohydrates , proteins , and fats ) to yield energy or perform the functions necessary to sustain life (such as building complex molecules and creating cellular structure). (newworldencyclopedia.org)

Multiple epidemiological studies have found links between OSAS and metabolic syndrome. (acc.org)

Obese (OB) patients are at increased risk of chronic kidney disease, but it is still unclear whether this can be attributed to obesity per se or to the associated metabolic derangements. (karger.com)
Clinically significant CKD is defined by an increased urinary albumin to creatinine ratio (UACR) and/or an estimated glomerular filtration rate (eGFR) lower than 60 mL/min/1.73 m 2 , as patients with these features are at much higher risk of disease progression [ 3 ]. (karger.com)
Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland coronary prevention study. (mja.com.au)
Robert K. Naviaux, MD, PhD, professor of medicine, pediatrics and pathology at University of California San Diego School of Medicine, and member of our OMF Scientific Advisory Board has just published, Metabolic features and regulation of the healing cycle - A new model for chronic disease pathogenesis and treatment on Science Direct. (end-mecfs.org)
In a new paper, available online in Mitochondrion in advance of publication, Robert K. Naviaux, MD, PhD, professor of medicine, pediatrics and pathology at University of California San Diego School of Medicine, posits that chronic disease is essentially the consequence of the natural healing cycle becoming blocked, specifically by disruptions at the metabolic and cellular levels. (end-mecfs.org)
The molecular features of this process are universal," said Naviaux, who also directs the Mitochondrial and Metabolic Disease Center at UC San Diego. (end-mecfs.org)
Another study suggests testosterone therapy can improve metabolic syndrome, decreasing the risk of diabetes and heart disease. (vitality101.com)
1 Metabolic syndrome constitutes a collection of interrelated risk factors of metabolic origin that increase the chances of developing heart disease, stroke, and diabetes. (acc.org)
Metabolic syndrome increases the risk for diabetes and heart disease. (nih.gov)
To prevent equine metabolic syndrome (EMS) in aging horses-or at least severe disease associated with it- veterinarians must keep up to date on the condition and its risk factors and management tactics. (thehorse.com)
Pulmonary vascular loss is an early feature of chronic obstructive pulmonary disease. (cdc.gov)

Metabolic gene clusters or biosynthetic gene clusters are tightly linked sets of mostly non-homologous genes participating in a common, discrete metabolic pathway. (wikipedia.org)

Anatomically, the ARC is considered a hypothalamic area that primarily senses metabolic signals from the periphery via the systemic circulation. (nature.com)
Petersén's hypothesis is that hypothalamic dysfunction is involved in causing the early psychiatric and metabolic features of HD. (lu.se)

Clinical features include muscle weakness. (msdmanuals.com)
The clinical features of Sanfilippo syndrome, including the significant CNS component (brain and spinal cord), result from the progressive lysosomal accumulation of the GAG heparan sulfate. (medscape.com)
The particular type of Sanfilippo syndrome cannot be determined based on clinical features alone. (medscape.com)
We compared comorbidities, clinical features and other predictive factors between COVID-19 patients requiring ICU admission for intubation/mechanical ventilation and all other COVID-19 cases in Selangor, Malaysia. (who.int)

Existing research provides conflicting evidence regarding the relationship between estimated branched-chain amino acid (BCAA) intake and metabolic, glycemic markers, and anthropometric characteristics. (biomedcentral.com)
With respect to the traditional metabolic markers, high third trimester glycated hemoglobin (HbA1c) levels at least 36 mmol/mol (5.4%) have been associated with an increased risk of diabetes mellitus in women with GDM from pregnancy up to five years postpartum (Claesson et al. (springer.com)

Clinical and metabolic characteristics (including non- esterified fatty acids , NEFA ) and GFR (combined Zappitelli equation) were assessed. (bvsalud.org)

The prevalence of metabolic and cardiovascular comorbidities increased with increasing OSA severity. (cdc.gov)

compared the incidence of metabolic syndrome in a group of 93 patients with a first episode of unprovoked DVT and in 107 controls.9 They found metabolic syndrome to be significantly more prevalent in patients with unprovoked DVT than in controls, with an adjusted odds ratio of 2.16 [95% confidence interval (CI) 1.19- 3.90]. (acc.org)

Even shortly after diagnosis, ab+/ins− patients feature partly preserved β -cell function and chronic hyperglycemia, which possibly contributes to the observed impairment of whole-body insulin sensitivity. (medscape.com)

[ 16 ] Some patients appear to developmicro- and macrovascular complications despite improved glycemic control [ 17 ] and independently of features of the so-called metabolic syndrome. (medscape.com)

We explored the metabolic features between SGFE and MV through liver metabolomics consequently. (physiciansweekly.com)

Volek JS, Feinman RD . Carbohydrate restriction improves the features of metabolic syndrome. (jcimjournal.com)

Hence, a metabolic signature at birth may help elucidate the mechanisms involved in metabolic health later in life. (nature.com)

Our goal at Metabolic Healing is to educate you about the many facets of living a holistic lifestyle, and to empower you with the skills and knowledge to make informed decisions about your own whole health. (metabolichealing.com)

2021 across BiG-SLiCE demonstrate the utility of such analyses by reconstructing a global map of secondary metabolic diversity across taxonomy to identify uncharted biosynthetic potential, opens up new possibilities to accelerate natural product discovery and offers a first step towards constructing a global and searchable interconnected network of BGCs. (wikipedia.org)
Virological and metabolic analyses were performed on (minimally invasive) collected oral swabs, rectal swabs, and nasal washes. (mdpi.com)

The brain integrates multiple metabolic inputs from the periphery through nutrients, gut-derived satiety signals and adiposity-related hormones. (nature.com)
1 The brain monitors changes in the body energy state by sensing alterations in the plasma levels of key metabolic hormones and nutrients. (nature.com)
These neurons are the first-order neurons on which peripheral metabolic hormones, including leptin, insulin, ghrelin and nutrients, primarily act. (nature.com)

To compare the use of complementary and alternative medicine (CAM), including dietary supplements, by individuals with and without features of metabolic syndrome (FeMS). (jcimjournal.com)

Specialized neuronal networks in the brain coordinate adaptive changes in food intake and energy expenditure in response to altered metabolic conditions ( Figure 1 ). (nature.com)

The sequence was applied to sub-second metabolic imaging of the rat in vivo after injection of hyperpolarized [1- 13 C]-pyruvate on a clinical 3T MR scanner. (sri.com)

Purpose - The purpose of this paper with meta-analysis is to clarify the effects of cranberry consumption on features of the metabolic syndrome of interest of all relevant randomized controlled trials (RCTs). (cranberryinstitute.org)
No significant effect of cranberry consumption on fasting blood glucose,high-density lipoprotein cholesterol, triglycerides and blood pressure was found in this meta-analysis.Originality/value - To the best of the authors' knowledge, this is the first systematic review with meta-analysis of RCTs that investigate the effect of cranberry consumption on features of the metabolic syndrome. (cranberryinstitute.org)

By the mid 1960s, defects that led to the accumulation of metabolic products in the urine, blood, or neural tissues were identified. (medscape.com)

The reduction in waist circumference and plasma cholesterol were larger with TU than with T gel, while the increases in plasma high-density lipoprotein and sex hormone binding globulin (an indicator of the severity of the metabolic syndrome) were larger with TU than with T gel. (vitality101.com)

The changes in this gas mixture between inhalation and exhalation, combined with a measurement of respiratory flow, can be used to estimate metabolic rate. (adinstruments.com)

Metabolic syndrome is a collection of conditions, including hypertension, high blood sugar, abnormal blood lipids, and excess body fat around the waist. (medicalnewstoday.com)

Risk associated with the metabolic syndrome versus the sum of its individual components. (mja.com.au)
But there was no link between those risk factors -- known collectively as metabolic syndrome -- and how much saturated fat or cholesterol kids ate. (lesliebeck.com)
It also finds that too little natural light can alter how fat cells behave and may increase the risk of metabolic syndrome. (medicalnewstoday.com)
Contrary to the above findings, in a post hoc analysis of the Heart Outcomes Prevention Evaluation (HOPE) study, the presence of metabolic syndrome was not found to be associated with an increased risk of VTE. (acc.org)

Pomegranate (Punica granatum Linn) is used in the prevention and treatment of metabolic syndrome in recent decades. (nih.gov)

A fast spiral chemical shift imaging (CSI) has been developed to address the challenge of the limited acquisition window in hyperpolarized 13 C metabolic imaging. (sri.com)
The presented results demonstrate that dramatic reductions in scan time are feasible in hyperpolarized 13 C metabolic imaging without a penalty in SNR or spatial resolution. (sri.com)

Herein, we investigated the metabolic response during viral shedding and post-shedding in an asymptomatic SARS-CoV-2 ferret model (n = 6) challenged with two SARS-CoV-2 isolates. (mdpi.com)
We have used the term, the cell danger response (CDR) to describe the chemical features that underlie this response. (omf.ngo)

The brain integrates metabolic signals from peripheral tissues such as the liver, pancreas, adipose tissue, gut and muscle. (nature.com)

After adjusting for age, body mass index (BMI), and smoking, OSAS patients were found to be nearly six times more likely to have metabolic syndrome than controls. (acc.org)
We carried out a cross-sectional study of 195 patients with metabolic syndrome. (who.int)
Metabolic features of these patients are insufficiently characterized at present. (medscape.com)

And since studies show that increasing AMPK activity can actually encourage your cells to stop storing fat and start burning it for energy, we've created AMPK Metabolic Activator. (ventrian.com)
Recently, a number of observational and case control studies have shown associations between OSAS, metabolic syndrome and procoagualant states. (acc.org)
As with OSA, a number of case control studies have been published exploring the potential association between the metabolic syndrome and VTE. (acc.org)
Petersén has published key studies identifying early psychiatric features in several HD animal models clearly indicating neurobiological mechanisms underlying these features. (lu.se)

Feature papers represent the most advanced research with significant potential for high impact in the field. (mdpi.com)
A person is thought to have metabolic syndrome if he or she has a large waist circumference plus two or more of the following: high blood triglycerides (blood fat), high blood pressure, elevated fasting blood glucose and low HDL (good) cholesterol. (lesliebeck.com)

Diseases2

Chemicals and Drugs2

Phenomena and Processes1

Disorders11

Pathways7

Insulin resistance2

Diseases10

Prediabetes3

Metabolism4

Obesity and METabolic2

Having metabolic syndrome2

Fatty liver disease1

Cardiovascular disease5

Endocrine1

Type 2 diabet3

Acidosis5

Acute metabolic2

Hypoglycemia1

Prediction1

Overweight5

Predict2

Inflammation2

Nutrient2

Epidemiological1

Disease11

Genes1

Hypothalamic2

Clinical Features4

Markers2

Characteristics1

Comorbidities1

Prevalent1

Chronic1

Glycemic1

Metabolomics1

Improves1

Elucidate1

Health1

Analyses2

Hormones3

Dietary1

Intake1

Vivo1

Consumption2

Urine1

Severity1

Respiratory1

Hypertension1

Risk4

Decades1

Imaging2

Response2

Tissues1

Patients3

Studies4

High2