Metabolic details of cellular senescence. Medical search. Frequent questions

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Anatomy31

Telomere Fibroblasts Cells, Cultured Cell Line, Tumor Cell Line Heterochromatin Plant Leaves Foreskin HCT116 Cells Cell Line, Transformed Intranuclear Inclusion Bodies Embryo, Mammalian Endothelial Cells Epithelial Cells Melanocytes Cell Nucleus Mitochondria Human Umbilical Vein Endothelial Cells HeLa Cells NIH 3T3 Cells Keratinocytes Skin Stem Cells Chromatin Lung Tumor Cells, Cultured Bile Ducts Mesenchymal Stromal Cells Flowers Hep G2 Cells Prostate

Organisms8

Mice, Knockout Mice, Inbred C57BL Mice, Transgenic Mice, Nude Arabidopsis Mice, Mutant Strains Plants, Genetically Modified Petunia

Diseases16

Aging, Premature Cell Transformation, Neoplastic Progeria Neoplasms Werner Syndrome Nevus, Pigmented Genomic Instability Airway Remodeling Atherosclerosis Prostatic Neoplasms Melanoma Liver Cirrhosis, Biliary Skin Neoplasms Inflammation Cell Transformation, Viral Disease Models, Animal

Chemicals and Drugs91

Cyclin-Dependent Kinase Inhibitor p16 Tumor Suppressor Protein p53 Cyclin-Dependent Kinase Inhibitor p21 Telomerase beta-Galactosidase Retinoblastoma Protein Tumor Suppressor Protein p14ARF Tumor Suppressor Proteins Sirtuin 1 Telomeric Repeat Binding Protein 2 Nuclear Proteins RNA, Small Interfering Reactive Oxygen Species Heterochromatin Hydrogen Peroxide DNA-Binding Proteins ras Proteins Repressor Proteins Transcription Factors Oxidants Cell Cycle Proteins TOR Serine-Threonine Kinases Histones Cyclin-Dependent Kinase Inhibitor p15 Polycomb Repressive Complex 1 Proto-Oncogene Proteins c-myc Inhibitor of Differentiation Protein 1 Sirtuins Toyocamycin Jumonji Domain-Containing Histone Demethylases Cyclin-Dependent Kinase Inhibitor p27 MicroRNAs Isopropyl Thiogalactoside RNA, Messenger Protein-Serine-Threonine Kinases Antigens, Nuclear Cyclin-Dependent Kinase 6 Biological Markers Proto-Oncogene Proteins c-mdm2 Papillomavirus E7 Proteins Ataxia Telangiectasia Mutated Proteins Neoplasm Proteins Proto-Oncogene Proteins p21(ras)RecQ Helicases DNA Intracellular Signaling Peptides and Proteins Caveolin 1 Cyclin-Dependent Kinase 4 E2F Transcription Factors Chlorophyll Histone Deacetylase 1 PTEN Phosphohydrolase Ethylenes Sirolimus Doxorubicin p38 Mitogen-Activated Protein Kinases Phosphatidylethanolamine Binding Protein RNA Cyclins Antineoplastic Agents Imidazoles Proteasome Endopeptidase Complex Chromosomal Proteins, Non-Histone Oncogene Proteins, Viral Acetylcysteine Proto-Oncogene Proteins Ubiquitin-Protein Ligases Antibiotics, Antineoplastic Trans-Activators DNA Primers Chromatin Exodeoxyribonucleases Cyclin-Dependent Kinases Plant Growth Regulators Proto-Oncogene Proteins c-akt Plant Proteins Enzyme Inhibitors Histone Deacetylases Proteins Arabidopsis Proteins Piperazines Antioxidants ADP-Ribosylation Factors Cytokinins Cyclin D1 Carrier Proteins Etoposide Protein Isoforms Superoxide Dismutase Histone Deacetylase Inhibitors Cyclopentanes

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Models, Biological Gene Knockdown Techniques Blotting, Western Reverse Transcriptase Polymerase Chain Reaction Transfection Chromatin Immunoprecipitation Immunoblotting Gene Expression Profiling Immunohistochemistry Flow Cytometry Real-Time Polymerase Chain Reaction Cell Culture Techniques Microarray Analysis Microscopy, Fluorescence Caloric Restriction Karyotyping Oligonucleotide Array Sequence Analysis In Situ Hybridization, Fluorescence Cell Count Disease Models, Animal Fluorescent Antibody Technique

Phenomena and Processes73

Cell Aging Telomere Telomere Shortening Aging DNA Damage Cell Proliferation Cell Cycle Checkpoints Cell Cycle Oxidative Stress Signal Transduction Longevity Genes, p16 Diploidy Phenotype Gene Expression Regulation RNA Interference Apoptosis Heterochromatin Down-Regulation Cell Division Oncogenes Up-Regulation Mutation Gene Silencing Genes, ras Gene Expression Regulation, Neoplastic Radiation Genomic Instability Telomere Homeostasis Genes, p53 Promoter Regions, Genetic Cell Shape Transcription, Genetic Transfection Time Factors Phosphorylation Base Sequence Gene Expression Epigenesis, Genetic Gamma Rays Autophagy Genes, Tumor Suppressor Acetylation DNA Repair Stress, Physiological Protein Binding Cell Survival Gene Expression Regulation, Plant Radiation, Ionizing Cell Differentiation Mitosis G1 Phase DNA Methylation Enzyme Activation Gene Deletion Airway Remodeling MAP Kinase Signaling System Chromatin Assembly and Disassembly Protein Processing, Post-Translational Chromatin Cell Death DNA Replication Cell Growth Processes Amino Acid Sequence Caloric Restriction Transcriptional Activation Protein Structure, Tertiary Ultraviolet Rays Wound Healing Protein Transport Oxidation-Reduction Cell Transformation, Viral Cell Count

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care1

Ultraviolet Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Information Science

Cell Aging Cyclin-Dependent Kinase Inhibitor p16 Telomere Fibroblasts Tumor Suppressor Protein p53 Aging, Premature Telomere Shortening Cyclin-Dependent Kinase Inhibitor p21 Telomerase beta-Galactosidase Aging DNA Damage Cells, Cultured Cell Proliferation Retinoblastoma Protein Cell Cycle Checkpoints Cell Cycle Cell Line, Tumor Oxidative Stress Cell Transformation, Neoplastic Signal Transduction Tumor Suppressor Protein p14ARF Cell Line Tumor Suppressor Proteins Sirtuin 1 Progeria Longevity Telomeric Repeat Binding Protein 2 Neoplasms Nuclear Proteins RNA, Small Interfering Genes, p16 Reactive Oxygen Species Diploidy Phenotype Gene Expression Regulation RNA Interference Apoptosis Heterochromatin Down-Regulation Models, Biological Werner Syndrome Hydrogen Peroxide DNA-Binding Proteins Gene Knockdown Techniques Cell Division ras Proteins Plant Leaves Repressor Proteins Transcription Factors Oxidants Oncogenes Up-Regulation Foreskin Nevus, Pigmented Cell Cycle Proteins Blotting, Western Mutation Mice, Knockout Gene Silencing HCT116 Cells TOR Serine-Threonine Kinases Genes, ras Histones Cyclin-Dependent Kinase Inhibitor p15 Polycomb Repressive Complex 1 Proto-Oncogene Proteins c-myc Cell Line, Transformed Inhibitor of Differentiation Protein 1 Gene Expression Regulation, Neoplastic Reverse Transcriptase Polymerase Chain Reaction Sirtuins Radiation Toyocamycin Genomic Instability Jumonji Domain-Containing Histone Demethylases Telomere Homeostasis Genes, p53 Cyclin-Dependent Kinase Inhibitor p27 MicroRNAs Isopropyl Thiogalactoside Intranuclear Inclusion Bodies RNA, Messenger Embryo, Mammalian Protein-Serine-Threonine Kinases Promoter Regions, Genetic Mice, Inbred C57BL Cell Shape Endothelial Cells Antigens, Nuclear Transcription, Genetic Transfection Time Factors Cyclin-Dependent Kinase 6 Epithelial Cells Biological Markers Proto-Oncogene Proteins c-mdm2 Papillomavirus E7 Proteins Molecular Sequence Data Phosphorylation

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