• New insights on the metabolism of branched-chain amino acids might shift this paradigm allowing more calories for a healthier diet. (thesciencebreaker.org)
  • Biochemical genetic testing and newborn screening are essential laboratory services for the screening, detection, diagnosis, and monitoring of inborn errors of metabolism or inherited metabolic disorders. (cdc.gov)
  • Changes in taxa abundance were associated with serum glucose and faecal branched-chain amino acids (BCAA), suggesting that fasting-induced changes in the gut microbiota are associated with host energy metabolism. (nih.gov)
  • These alterations can affect the metabolism of tryptophan (TRP), an essential amino acid and precursor of serotonin (5-HT), kynurenine (KYN), and indoles. (frontiersin.org)
  • A growing body of evidence indicates that inflammation is associated with alterations in the metabolism of tryptophan (TRP) ( 12 , 13 ), an essential amino acid and biochemical precursor of serotonin (5-HT), kynurenine (KYN) and indoles ( 14 ). (frontiersin.org)
  • One group of these disorders is amino acid metabolism disorders. (medlineplus.gov)
  • However, amino acid metabolism in dental plaque is still unclear. (bvsalud.org)
  • More specifically, these results indicate the potential capacity for metabolism of l-Asp and l-Glu by skeletal muscle, and l-Gln absorption by kidneys, but no change in hepatic expression of l-Gln metabolism, elaborates previous metabolic studies by revealing molecular-level responses to metabolic acidosis in sheep. (uky.edu)
  • Ethanol, higher alcohols, fatty acids and esters, all of which are important to the sensory perception of wine, are also derived from sugar metabolism. (winemakermag.com)
  • Amino acid metabolism plays a vital role in cancer biology. (frontiersin.org)
  • However, the application of amino acid metabolism in the prognosis of colon adenocarcinoma (COAD) has not yet been explored. (frontiersin.org)
  • Here, we construct an amino acid metabolism-related risk model to predict the survival outcome of COAD and improve clinical decision making. (frontiersin.org)
  • Differential expression of amino acid metabolism-related genes (AAMRGs) was identified for prognostic gene selection. (frontiersin.org)
  • Apart from the well-known Warburg effect, metabolic alterations in lipid and amino acid metabolism have been observed in a number of tumors, including colorectal cancer, lung cancer, and breast cancer ( 7 ). (frontiersin.org)
  • Mounting evidence have indicated that changes in amino acid metabolism contributed to the metastasis, proliferation, angiogenesis, and drug resistance of colorectal cancer ( 8 - 11 ). (frontiersin.org)
  • Meanwhile, new insights into the metabolic signatures of tumors have revealed the potential of risk prediction model, which is based on the amino acid metabolism-related genes (AAMRG) ( 13 , 14 ). (frontiersin.org)
  • In addition, amino acid metabolism plays an important role in regulating tumor immunity and targeting amino acid metabolism may help to overcome immunotherapy resistance and improve existing therapies for COAD patients. (frontiersin.org)
  • Therefore, targeting the amino acid metabolism might provide novel ideas for the diagnosis and management of COAD. (frontiersin.org)
  • This poster summarizes the acute and long-term metabolic effects of PKU GOLIKE supplementation on the utilization of amino acids and glucose metabolism in a pre-clinical rat model using biomarkers for muscle metabolism, functional muscle performance and a glucose tolerance test. (biospace.com)
  • Due to the prolonged-release of amino acids engineered with Physiomimic Technology, beneficial effects were observed on amino acid oxidation, muscle metabolism, grip strength and glucose tolerance in healthy rats. (biospace.com)
  • Analytical methods such as mass spectrometry and nuclear magnetic resonance spectroscopy allow our team to study metabolic consequences of altered energy and protein metabolism. (mayo.edu)
  • PLP is a coenzyme of tryptophan, methionine, and gamma aminobutyric acid (GABA) metabolism. (medscape.com)
  • Metabolic disorders and disruption of metabolism. (aber.ac.uk)
  • The journal aims to cover a broad range of topics related to amino acids, including their biosynthesis, catabolism, metabolism, transport, signaling, and functions in the body. (springer.com)
  • In addition, the journal features articles on the nutritional and dietary aspects of amino acids, such as their dietary intake, supplementation, and metabolism, and how these factors influence human health and disease. (springer.com)
  • Methylmalonic acidemia is an autosomal recessive disorder of amino acid metabolism, involving a defect in the conversion of methylmalonyl-coenzyme A (CoA) to succinyl-CoA. (medscape.com)
  • Metabolic pathway enrichment identified 41 pathways associated with benzene exposure, with altered pathways including carnitine shuttle, fatty acid metabolism, sulfur amino acid metabolism, glycolysis, gluconeogenesis and branched chain amino acid metabolism. (cdc.gov)
  • These results suggest disruption to fatty acid uptake, energy metabolism and increased oxidative stress, and point towards pathways related to mitochondrial dysfunction, which has previously been linked to benzene exposure in animal models and human studies. (cdc.gov)
  • The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. (tamu.edu)
  • Lower birthweight adjusted for gestational age is associated with adverse biomarker aberrations across multiple metabolic pathways. (nih.gov)
  • Coherent metabolic signatures between lower birthweight and higher adult adiposity suggest that shared molecular pathways may potentially underpin the metabolic deviations. (nih.gov)
  • Intriguingly, we find that feeding mice a diet specifically reduced in branched-chain amino acids (BCAAs) is sufficient to improve glucose tolerance and body composition equivalently to a PR diet via metabolically distinct pathways. (wustl.edu)
  • HsIL-6 and hsCRP were increased in obesity and were overall associated with TRP metabolic pathways alterations. (frontiersin.org)
  • These results indicate for the first time that KYN and indole TRP metabolic pathways are concomitantly altered in obese subjects and highlight their respective associations with obesity-related systemic inflammation. (frontiersin.org)
  • The obtained metabolome profile revealed that amino acids are degraded through various metabolic pathways , including deamination , decarboxylation and transamination and that these metabolic systems may link each other, as well as with carbohydrate metabolic pathways in dental plaque ecosystem . (bvsalud.org)
  • All of the yeast's metabolic pathways are interconnected. (winemakermag.com)
  • Comparison of these two types of fiber revealed significant higher 13C enrichment in inulin treated samples compared to cellulose, reflecting distinct metabolic pathways of dietary fibers in the gut microbiome, which could be related with host effects. (usda.gov)
  • Is the Subject Area "Metabolic pathways" applicable to this article? (plos.org)
  • Transcriptional regulation of the genes in metabolic pathways is a highly successful strategy, which is virtually universal in microorganisms. (lu.se)
  • When a second nutrient and its metabolic pathway are introduced, the system must further decide whether and how to activate both pathways. (lu.se)
  • Citation: Troein C, Ahre´n D, Krogh M, Peterson C (2007) Is Transcriptional Regulation of Metabolic Pathways an Optimal Strategy for Fitness? (lu.se)
  • A number of studies have explored how regulation of generally, and at least to a first approximation, it is obvious that metabolic pathways affects the growth rate of microorganisms, gene regulation only is useful if the environmental conditions vary both in the steady state and in response to changes in the local with time. (lu.se)
  • Existing research provides conflicting evidence regarding the relationship between estimated branched-chain amino acid (BCAA) intake and metabolic, glycemic markers, and anthropometric characteristics. (biomedcentral.com)
  • This research seeks to examine the association between estimated dietary BCAA consumption and glycemic, and metabolic markers, as well as anthropometric parameters in adults classified as overweight or obese. (biomedcentral.com)
  • We discovered that feeding these mice a low BCAA diet rapidly improved their metabolic health, making them as lean as mice that had never eaten a Western diet and restoring their ability to regulate blood sugar. (thesciencebreaker.org)
  • While the exact physiological and molecular mechanisms responsible for the metabolic benefits of a low BCAA diet are not yet understood, a hormone called FGF21 produced by the liver may be involved. (thesciencebreaker.org)
  • One puzzle about our study is that BCAA supplements are routinely taken by many athletes without obvious negative effects on metabolic health - indeed, many health benefits have been attributed to BCAAs. (thesciencebreaker.org)
  • If humans respond to dietary BCAAs in a way that is similar to mice, we think that lowering the amount of BCAAs in the diet - or identifying pharmaceuticals that mimic the effects of a low BCAA diet - could be an effective way to treat or prevent metabolic syndrome. (thesciencebreaker.org)
  • Lower levels of the branched-chain amino acid (BCAA) valine ( p = 8.6 × 10 −6 ) were predictive of overweight in childhood. (nature.com)
  • Should I Take BCAA (Branched-Chain Amino Acids) Everyday? (medicinenet.com)
  • These recommendations are intended for laboratories that perform biochemical genetic testing to improve the quality of laboratory services and for newborn screening laboratories to ensure the quality of laboratory practices for inherited metabolic disorders. (cdc.gov)
  • If you have one of these disorders, your body may have trouble breaking down certain amino acids. (medlineplus.gov)
  • Our working hypothesis was that by undertaking comprehensive examination of metabolic profiles, in addition to traditional metabolic markers, it could be possible to elucidate the associations of circulating metabolites during pregnancy to postpartum metabolic disorders and thus to reveal potential targets for interventions. (springer.com)
  • The data will be presented in a poster session at the Society for Inherited Metabolic Disorders (SIMD) 44th Annual Meeting in Salt Lake City, March 18-21, 2023. (biospace.com)
  • The journal also aims to provide a platform for researchers to publish their findings on the therapeutic applications of amino acids and their derivatives in the treatment of various diseases, such as metabolic and neurological disorders, cancer, and cardiovascular diseases. (springer.com)
  • Nyhan and Sakati stated that the true prevalence may be higher because many neonatal deaths may be caused by unrecognized metabolic disorders. (medscape.com)
  • Increasingly, tandem mass spectrometry (MS/MS) is being used for newborn screening because this laboratory testing technology substantially increases the number of metabolic disorders that can be detected from dried blood-spot specimens. (cdc.gov)
  • The same is true for the biosynthesis of tryptophan, with the first step being N-alkylation of anthranilic acid catalysed by the enzyme anthranilate phosphoribosyltransferase. (wikipedia.org)
  • Pathway: 5-aminoimidazole ribonucleotide biosynthesis I". MetaCyc Metabolic Pathway Database. (wikipedia.org)
  • Carbon (13C) from soluble (inulin) and insoluble (cellulose) fibers were utilized by gut microbiome to a different extent in the biosynthesis of amino acids, pantothenic acid and co-factors. (usda.gov)
  • Primary amino nitrogen (PAN) and ammonia are used by yeast, and are known collectively as yeast assimilable nitrogen (YAN). (winemakermag.com)
  • The rate of amino acid absorption affects the post-prandial utilization of dietary nitrogen, and the prolonged release of amino acids could support anabolic requirements. (biospace.com)
  • BUN (Blood urine nitrogen test) was significantly lower in the acute treatment with PKU GOLIKE indicating the potential to improve amino acid utilization in PKU patients resulting in a reduction of catabolic episodes. (biospace.com)
  • ABSTRACT: We investigated the nitrogen isotopic compositions of individual amino acids from brown and red macroalgae and gastropods in a natural marine coastal environment, to further evaluate them as a tool for ecological studies and to understand the factor(s) controlling the isotopic compositions in terms of biosynthetic and metabolic processes. (int-res.com)
  • The nitrogen isotopic variation between amino acids strongly reflects their biosynthetic and metabolic processes. (int-res.com)
  • In particular, we suggest here that metabolic fate is an important factor in producing distinct trophic relationships in nitrogen isotopic compositions between amino acids. (int-res.com)
  • This metabolic plasticity of aspartate enables carbon-nitrogen budgeting, thereby driving the biochemical self-organization of distinct cell states. (elifesciences.org)
  • The former can be degraded to acids mainly, while the latter can be degraded to various metabolites, including ammonia , acids and amines , and associated with acid -neutralization, oral malodor and tissue inflammation . (bvsalud.org)
  • Amino acids and the related metabolites in supragingival plaque were extracted and quantified comprehensively by CE-TOFMS. (bvsalud.org)
  • Plaque samples were also incubated with amino acids , and the amounts of ammonia and amino acid -related metabolites were measured. (bvsalud.org)
  • Random Forests classifiers, based on the metabolic profiles, were used to predict the prediabetes status, and correlations of the metabolites to glycemic traits (fasting glucose and insulin, HOMA2-IR and HbA1c) and hsCRP at postpartum were evaluated. (springer.com)
  • In non-pregnant populations, certain distinct serum metabolites, such as the levels of branched-chain amino acids (BCAAs), as well as those of phenylalanine, glutamate and several lipids, have been associated with an elevated risk of type 2 diabetes (Long et al. (springer.com)
  • Irrespective of the LAB biodiversity, a large majority of the sugar and amino acid metabolites were detected in all sourdough samples. (who.int)
  • The metabolites of note included small fatty acids such as decanoic and octanoic acid, amino acids such as serine and 1H-indole-3-acetic acid, and sugar derivatives such as glycerol. (medscape.com)
  • Decanoic acid and some of these other metabolites that they're looking at are not traditional biomarkers," said Donald Marion, MD, MSc, senior consultant with the Defense and Veterans Brain Injury Center in Silver Spring, Maryland. (medscape.com)
  • An inherited metabolic disorder that is characterized by impaired synthesis and degradation of amino acids. (mcw.edu)
  • The availability of certain key amino acids influences protein synthesis, because amino acids are required in set proportions to manufacture a given protein. (readabstracts.com)
  • This will necessitate students undertaking background reading and research to obtain a more detailed understanding of the metabolic processes involved in the laboratory work. (aber.ac.uk)
  • Amino acids regulate almost all of the metabolic processes in the human body. (webmd.com)
  • The involvement of D-amino acids in bacterial metabolic processes makes the enzyme inhibitors of potential value as anti-bacterial drugs. (europa.eu)
  • PLP is a cofactor for glutamic acid decarboxylase, the enzyme that produces GABA, such that PLP deficiency results in insufficient GABA. (medscape.com)
  • Muscles have the enzyme branched-chain-amino-acid aminotransferase (BCAT), which enables them to use these amino acids. (medicinenet.com)
  • The metabolic enzyme modulation also leads to incidences of altered bioavailability and pharmacokinetics of therapeutic substrates. (hindawi.com)
  • Babies with PKU can't make an enzyme needed to break down phenylalanine (Phe) - an amino acid found in protein. (webmd.com)
  • Moreover, glutamine and glutamate might be the main source of ammonia production , as well as arginine , and contribute to pH - homeostasis and counteraction to acid -induced demineralization in supragingival plaque. (bvsalud.org)
  • Roles of neuroactive amino acids in ammonia neurotoxicity. (cdc.gov)
  • 1987. Ammonia emissions and their role in acid deposition. (cdc.gov)
  • The prevalence of metabolic syndrome is increasing worldwide, especially in Asian populations. (nature.com)
  • However, little is known about whether the altered plasma free amino acid profiles in subjects with metabolic syndrome are related to the effectiveness of dietary and exercise interventions. (nature.com)
  • Eighty-five Japanese subjects who fulfilled the Japanese diagnostic criteria for metabolic syndrome were enrolled in a 3-month diet and exercise intervention. (nature.com)
  • These data suggest that among Japanese adults meeting the criteria for metabolic syndrome, baseline plasma free amino acid profiles may differ in ways that predict who will be more vs less beneficially responsive to a standard diet and exercise program. (nature.com)
  • Metabolic syndrome is a pathophysiological state that brings about diabetes, hypertension and dyslipidemia, and is also a major risk factor for cardiovascular disease or ischemic heart disease. (nature.com)
  • 3 Owing to the global shift toward a Western lifestyle of eating and sedentary habits, the prevalence of metabolic syndrome has been consistently increasing worldwide, especially in Asian populations. (nature.com)
  • It is widely accepted that early detection and early intervention are critical for preventing lifestyle-related diseases, including metabolic syndrome. (nature.com)
  • Could Branched-Chain Amino Acids Be a New Landmark in Metabolic Syndrome and Cardiac Arrhythmias? (ogu.edu.tr)
  • Background: Although metabolic syndrome (MetS) was described in the late 80s, the molecular mechanisms underlying clustering of risk factors in certain individuals are not fully understood. (lu.se)
  • The vitamins thiamine and cobalamin, and the amino acid tryptophan also contain fragments derived from PRPP. (wikipedia.org)
  • Amino Acids is an international peer-reviewed journal dedicated to publishing high-quality research related to the chemistry, biochemistry, physiology, pharmacology, and toxicology of amino acids and related compounds. (springer.com)
  • Plasma free amino acid profile is a potential biomarker for the early detection for lifestyle-related diseases. (nature.com)
  • Plasma free amino acid profiles may also be useful as markers for monitoring the risks of developing lifestyle-related diseases and measuring improvement in physiological states. (nature.com)
  • In the past few decades, metabolic diseases have emerged as some of the most significant public health problems worldwide. (biomedcentral.com)
  • Obesity, fatty liver, and diabetes are now among the most prevalent metabolic diseases across all age groups. (biomedcentral.com)
  • Obesity has reached epidemic proportions in many countries around the world and is closely associated with several chronic diseases, including metabolic disease. (biomedcentral.com)
  • As the number of inherited metabolic diseases that are included in state-based newborn screening programs continues to increase, ensuring the quality of performance and delivery of testing services remains a continuous challenge not only for public health laboratories and other newborn screening facilities but also for biochemical genetic testing laboratories. (cdc.gov)
  • The recommended practices address the benefits of using a quality management system approach, factors to consider before introducing new tests, establishment and verification of test performance specifications, the total laboratory testing process (which consists of the preanalytic, analytic, and postanalytic phases), confidentiality of patient information and test results, and personnel qualifications and responsibilities for laboratory testing for inherited metabolic diseases. (cdc.gov)
  • Fasting is increasingly popular to manage metabolic and inflammatory diseases. (nih.gov)
  • Small human trials have assessed taurine as a treatment for metabolic diseases, with some positive results . (livescience.com)
  • Go to Neuro-vascular Diseases for more information on metabolic diseases and stroke. (medscape.com)
  • Protein-restricted (PR), high-carbohydrate diets improve metabolic health in rodents, yet the precise dietary components that are responsible for these effects have not been identified. (wustl.edu)
  • The powder and alcoholic extract of dried seeds of garden cress were investigated for their effect on metabolic activity of CYP2D6 and CYP3A4 enzymes. (hindawi.com)
  • Dextromethorphan was used as a common marker for measuring metabolic activity of CYP2D6 and CYP3A4 enzymes. (hindawi.com)
  • The metabolic activities of enzymes CYP3A4 and CYP2D6 were assessed. (hindawi.com)
  • The main focus of the journal is to publish research studies that enhance our understanding of the biological and physiological roles of amino acids in the human body as well as plants and microbes. (springer.com)
  • These metabolic biomarkers found to be associated with a diagnosis of TBI also scaled with outcome, and were strongly associated with the worst patient outcomes. (medscape.com)
  • Here, we demonstrate in a randomized controlled trial that a moderate PR diet also improves markers of metabolic health in humans. (wustl.edu)
  • Obesity is a metabolic disorder characterized by a chronic low-grade inflammatory state, as reflected in increased levels of circulating inflammatory markers, including pro-inflammatory cytokines and the acute phase protein C-reactive protein (CRP) ( 1 - 4 ). (frontiersin.org)
  • With respect to the traditional metabolic markers, high third trimester glycated hemoglobin (HbA1c) levels at least 36 mmol/mol (5.4%) have been associated with an increased risk of diabetes mellitus in women with GDM from pregnancy up to five years postpartum (Claesson et al. (springer.com)
  • Further investigation is warranted to elucidate mechanisms and confirm benefits of foods rich in these amino acids on cardiovascular outcomes. (nutraingredients-usa.com)
  • This study aimed to elucidate what kinds of amino acids are available as metabolic substrates and how the amino acids are metabolized in supragingival plaque, by a metabolome analysis . (bvsalud.org)
  • Hence, a metabolic signature at birth may help elucidate the mechanisms involved in metabolic health later in life. (nature.com)
  • To a lesser extent, odd-chain fatty acid and cholesterol degradation also contribute. (medscape.com)
  • While most such popularized diet plans have focused on the negative health effects of dietary fat or sugar, studies by our laboratory and others have linked low protein diets with both improved metabolic health and a decreased risk of diabetes in humans. (thesciencebreaker.org)
  • Our results highlight a critical role for dietary quality at the level of amino acids in the maintenance of metabolic health and suggest that diets specifically reduced in BCAAs, or pharmacological interventions in this pathway, may offer a translatable way to achieve many of the metabolic benefits of a PR diet. (wustl.edu)
  • This decline is likely linked to the body's ability to make taurine rather than to a change in diet, since plant-based diets (which are low in taurine) haven't been linked to such a dramatic decline in the amino acid, Baur said. (livescience.com)
  • High-throughput nuclear magnetic resonance metabolomics and biochemical assays were used to quantify 87 circulating metabolic measures in seven cohorts from Finland and the UK, comprising altogether 18 288 individuals (mean age 26 years, range 15-75). (nih.gov)
  • "Although no previous studies have examined this combination of amino acids on vascular function, we hypothesized that the active ingredients of the supplement would act synergistically to improve endothelial function by reducing oxidative stress and inflammation," ​ wrote the researchers. (nutraingredients-usa.com)
  • The findings provide direction for our forthcoming clinical research to confirm the metabolic benefits of PKU GOLIKE, assessing body composition and oxidative stress in active PKU patients, thereby substantiating our completed pre-clinical work. (biospace.com)
  • Garden cress decreases the level of DOR and 3-MM in urine and significantly increases the urinary metabolic ratio of DEX/DOR and DEX/3-MM. The findings suggested that garden cress seeds powder and ethanolic extract have the potential to interact with CYP2D6 and CYP3A4 substrates. (hindawi.com)
  • If you have a metabolic disorder , something goes wrong with this process. (medlineplus.gov)
  • In the gut, TRP is metabolized by specific intestinal bacteria ( 23 ) into indole, indole-3-acetic acid (IAA), indole-3-acrylic acid (IA), indole-3-carboxalaldehyde (ICAld), indole-3-lactic acid (ILA), indole-3-propionic acid (IPA), indole-3-ethanol (IE), indole-3-acetonitrile (IACN), and indole-3-carboxylic acid (ICA) ( 24 ). (frontiersin.org)
  • A total of 1,194 potential lactic acid bacterium (LAB) isolates were tentatively grouped and identified by repetitive element sequence-based PCR, followed by sequence-based identification using 16S rRNA and pheS genes from a selection of genotypically unique LAB isolates. (who.int)
  • 2019). We now discover that the plasticity of use of a non-limiting resource, aspartate, controls both resource production and the emergence of heterogeneous cell states, based on differential metabolic budgeting. (elifesciences.org)
  • For example, when calorie intake is curtailed as in starvation, the metabolic rate slows down so that less energy is used for basic body functions. (readabstracts.com)
  • The serum metabolic profile during pregnancy might be used to identify women at increased risk for type 2 diabetes. (springer.com)
  • It has previously been demonstrated, in a cohort of women with overweight, that the serum metabolic profile of women developing GDM differs from those who remain normoglycemic already in early pregnancy (Mokkala et al. (springer.com)
  • We wanted to investigate the associations of early and late pregnancy serum metabolic profiles to the prediabetes status at two years' postpartum in an at-risk cohort of women who had overweight before becoming pregnant. (springer.com)
  • Some authors suggest that the accumulation of methylmalonic acid and odd-chain fatty acids may be directly toxic to neuronal and glial cells. (medscape.com)
  • The Pharmacologic Actions tree was also expanded to include 48 new headings and a new major category Metabolic Side Effects of Drugs and Substances' was created to accommodate a broad variety of side effects that drugs have on the cytochrome P-450 system. (bvsalud.org)
  • In this study, we have investigated the cord blood metabolic signatures of rapid growth in infancy and overweight in early childhood in four European birth cohorts. (nature.com)
  • The Metabolic Basis for Type 2 Diabetes and Aging Research Laboratory studies the mechanisms and complications of type 2 diabetes to help inform and improve quality of life for the aging population. (mayo.edu)
  • People living with PKU do not have the ability to metabolize the amino acid phenylalanine (Phe) found in many foods and they require supplementation of amino acid-based foods for special medical purposes (FSMPs) to prevent protein deficiency and optimize metabolic control. (biospace.com)
  • People living with PKU require supplementation of amino acids formulated as foods for special medical purposes (FSMP) to prevent protein deficiency. (biospace.com)
  • Amino acid composition and amino acid-metabolic network in supragingival plaque. (bvsalud.org)
  • The results from this pre-clinical research demonstrate the important body composition benefits of the physiological absorption of our prolonged-release amino acid supplement PKU GOLIKE 1 ," said Nermeen Varawalla, M.D., Ph.D., chief medical officer at Relief Therapeutics. (biospace.com)
  • Experiments suggest that taurine, an unusual amino acid, can extend some animals' life spans, but it's unclear if it would work in humans. (livescience.com)
  • This gene encodes a member of the aromatic amino acid hydroxylase family. (nih.gov)
  • These concepts are illustrated with examples of amino acid flux and protein turnover. (readabstracts.com)
  • The plasma free amino acid concentrations and metabolic variables were measured, and the relationships between plasma free amino acid profiles, metabolic variables and the extent of body weight reduction were investigated. (nature.com)
  • The resemblance indicated that 1 kg lower birthweight is associated with similar metabolic aberrations as caused by 0.92 units higher BMI in adulthood. (nih.gov)