Metabolic abnormalities glucose metabolic syndrome is central obesity. Medical search. Frequent questions

Patients were oriented to the objec- sity lipoprotein (HDL) cholesterol], This clinic provides primary care to a tives of the study and their consent was hypertension, central obesity and ele- socially diversified group of patients secured. (who.int)
We do agree that anybody with an A1c of 5.5% to 6.4% has glucose abnormalities, but we also know that many of them may already have diabetes based on glucose criteria," said Dr. Handelsman, adding that the organizations view metabolic syndrome, the cluster of such cardiovascular risk factors as hypertension and central obesity, as equivalent to prediabetes in terms of its associated risk of developing diabetes and cardiovascular disease. (acpinternist.org)
A dysfunctional HPA-axis causes high cortisol levels to circulate, which results in raising glucose and insulin levels, which in turn cause insulin-mediated effects on adipose tissue, ultimately promoting visceral adiposity, insulin resistance, dyslipidemia and hypertension, with direct effects on the bone, causing "low turnover" osteoporosis. (wikipedia.org)
Obesity has definitely become a growing problem, but a lot of anti-obesity educations, with fen-peen as the best example, have proven to have very damaging side-effects like lung hypertension and heart valve condition (Fen Peen, 2010). (directcurrentmusic.com)
BACKGROUND: Metabolic syndrome (MetS) is a group of metabolic abnormalities characterised by hypertension, central obesity, dyslipidaemia and dysregulation of blood glucose, associated with the risk of diabetes, cardiovascular disease and overall mortality. (bvsalud.org)
In sub-Saharan Africa, hypertension followed by obesity was the commonly known cardiometabolic risk factors associated with the general adult population [ 8 ]. (hindawi.com)
Cardiovascular disease (CVD) risk factors such as obesity, hypertension, and dyslipidaemia are common in patients with DM, placing them at increased risk for cardiac events [ 10 , 11 ]. (hindawi.com)
Metabolic syndrome is defined as a cluster of metabolic abnormalities including obesity, hyperlipidemia, hyperglycemia, insulin resistance, and hypertension [ 3 ]. (hindawi.com)
At this point, high insulin levels are often associated with central obesity, cholesterol abnormalities, and/or high blood pressure (hypertension). (diabeteshealthmatters.com)
Metabolic syndrome (MetS) is characterized by a cluster of several metabolic and cardiovascular risk factors such as abdominal obesity, insulin resistance, atherogenic dyslipidemia, and hypertension [ 1 - 3 ]. (itmedicalteam.pl)
Assess patients with primary hypertriglyceridemia for other cardiovascular risk factors such as central obesity, hypertension, abnormalities of glucose metabolism, and liver dysfunction. (guidelinecentral.com)
Besides effective control of blood pressure in patients with hypertension, third-generation beta-blockers such as nebivolol offer additional benefits for central hemodynamics and neutral or beneficial effects on metabolism. (nih.gov)
The present article will provide a systematic analysis of the pathophysiological links among hypertension, insulin resistance, and metabolic syndrome. (nih.gov)
Thus, nebivolol could be a favorable therapeutic option for the treatment of hypertension in patients with impaired glucose and lipid metabolism. (nih.gov)
Ce syndrome se caractérise par l'association d'anomalies incluant une résistance à l'insuline, un hyper-insulinisme, une intolérance au glucose ou un diabète de type 2, une hypertension artérielle et des troubles du métabolisme lipidique et de la coagulation. (erudit.org)
It is characterized by a cluster of risk factors of atherosclerosis including insulin resistance, hyperinsulinemia, impaired glucose tolerance or type 2 diabetes, hypertension, dyslipidemia, and coagulation abnormalities. (erudit.org)
Blood pressure measurement is important, because hypertension is a frequent component of the dysmetabolic syndrome. (medscape.com)
Approximately 40% of individuals with hypertension have impaired glucose tolerance. (medscape.com)
Primary care providers should be alert to the importance of screening patients with hypertension for metabolic syndrome to prevent and manage these combined conditions. (who.int)
Metabolic Syndrome Metabolic syndrome is characterized by a large waist circumference (due to excess abdominal fat), hypertension, abnormal fasting plasma glucose or insulin resistance, and dyslipidemia. (merckmanuals.com)
The increasing prevalence of hypertension and lipid abnormalities as well as diabetes also poses some challenges in addition to the rising health care cost. (biomedcentral.com)
The metabolic syndrome is a cluster of risk factors that include hypertension, impaired glucose tolerance or diabetes mellitus, central obesity and dyslipidaemia. (biomedcentral.com)
Methods: Metabolic syndrome is ≥3 of the following: hypertriglyceridemia, low high-density lipoprotein (HDL) cholesterol, hypertension, abdominal obesity, and high serum glucose. (natap.org)
It is suggested that until the epidemic progression of obesity is stopped and obesity prevented or at least properly managed, cardiologists will be confronted to an evolving contribution of risk factors where smoking, hypercholesterolemia and hypertension may be relatively less prevalent but at the expense of a much greater contribution of abdominal obesity and related features of the metabolic syndrome. (researchgate.net)
Metabolic Syndrome" (MetS), refers to the clustering of abdominal obesity, impaired glucose tolerance, hypertriglyceridemia, diminished high density lipoprotein (HDL) cholesterol, and/or hypertension in an individual. (kauveryhospital.com)
The high prevalence of obesity and obesity-related metabolic abnormalities (e.g., type 2 diabetes, hypertension) in children and adolescents continues to increase worldwide. (jomes.org)
It is related to various cardio-metabolic risk factors such as hyperglycemia, dyslipidemia, and hypertension. (e-apem.org)
Downstream from these adverse effects of insulin resistance are clinically measured abnormalities such as hypertension and dyslipidemia (e.g., high triglyceride levels and low HDL cholesterol levels). (diabetesjournals.org)
Une recherche documentaire a été effectuée dans PubMed de 1980 à 2021 en utilisant diverses combinaisons de termes MeSH comme tabac, diabète, hypertension, dyslipidémie, trouble dépressif majeur, trouble bipolaire, schizophrénie. (bvsalud.org)

Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). (wikipedia.org)
HPA-axis dysfunction may explain the reported risk indication of abdominal obesity to cardiovascular disease (CVD), type 2 diabetes and stroke. (wikipedia.org)
This has led to an increasing evidence for abdominal obesity indices such as waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) as predictors of CVD [ 16 , 17 ]. (hindawi.com)
Waist circumference was anddiabetesthatincludeshyperten- familypracticeclinicattheUniversity measuredusingasteelmeasuringtape, sion,glucoseintolerance,dyslipidaemia ofJordanHospitalwerescreenedfor atthepointhalfwaybetweenthelower and abdominal obesity. (who.int)
However, even in the absence of the hyperglycaemic state which characterizes type 2 diabetic patients, non diabetic individuals with a specific form of obesity, named abdominal obesity, often show clustering metabolic abnormalities which include high triglyceride levels, increased apolipoprotein B, small dense low density lipoproteins and decreased high density lipoproteins-cholesterol levels, a hyperinsulinemic-insulin resistant state, alterations in coagulation factors as well as an inflammatory profile. (researchgate.net)
This agglomeration of abnormalities has been referred to as the metabolic syndrome which can be identified by the presence of three of the five following variables: abdominal obesity, elevated triglyceride concentrations, low HDL-cholesterol levels, increased blood pressure and elevated fasting glucose. (researchgate.net)
Post-mortem analyses of coronary arteries have indicated that obesity (associated with a high accumulation of abdominal fat measured at autopsy) was predictive of earlier and greater extent of large vessels atherosclerosis as well as increase of coronary fatty streaks. (researchgate.net)
Metabolic syndrome linked to abdominal obesity is also predictive of recurrent coronary events both in post-myocardial infarction patients and among coronary artery disease men who underwent a revascularization procedures. (researchgate.net)
Central or abdominal obesity is a typical pattern. (bodynhealth.org)
31 The presence of abdominal obesity is more highly correlated with the metabolic risk factors than is an elevated BMI. (slideplayer.com)

Metabolic syndrome (MetS) is associated with several degenerative diseases, including retinal degeneration. (molvis.org)
In this study, we investigated the additional effect of impaired glucose tolerance (IGT), an essential component of MetS, on retinal degeneration using the WNIN/GR-Ob rat model. (molvis.org)
The alarming increase in the prevalence of obesity or MetS is likely to further exacerbate the risk for ophthalmic abnormalities associated with obesity. (molvis.org)
The presence of elevated liver enzymes may precede the development of MetS, with alterations of the liver being observed that are directly related to metabolic problems. (bvsalud.org)
BACKGROUND: Metabolic syndrome (MetS) is a constellation of risk factors increasingly present in the world's population. (bvsalud.org)
The relationship between tea and coffee consumption and mortality among patients with metabolic syndrome (MetS) remains barely explored. (biomedcentral.com)
Explain the relationship between metabolic syndrome (MetS) and periodontal disease, and a potential assessment tool for MetS risk. (dimensionsofdentalhygiene.com)
The aim of this study was to evaluate acylated ghrelin and obestatin levels and their ratio in obese and normal-weight children and adolescents, and their association with metabolic syndrome (MetS) parameters. (mdpi.com)
Background: Warning signs of metabolic syndrome (MetS) can appear during childhood. (itmedicalteam.pl)
Conclusions: The prevalence of MetS among overweight and obese Palestinian schoolchildren is high with dyslipidemia being the most common MetS abnormality. (itmedicalteam.pl)
Metabolic Syndrome (MetS) and Type 2 diabetes (T2D) are clinical conditions involving the impaired uptake and utilization of glucose, altered lipid metabolism, and the disruption of the metabolic signaling pathways that regulate insulin secretion from pancreas ( 1 ). (frontiersin.org)
The severity of the metabolic syndrome (MetS) is significantly associated with future coronary heart disease (CHD) among individuals without baseline Type 2 diabetes. (biomedcentral.com)
We used Cox-regression techniques to assess hazard ratios (HR) of CHD based on a sex- and race/ethnicity-specific MetS-severity Z-score (standard MetS score) and a similar MetS-severity score formulated without incorporating glucose as a component of MetS (no-glucose MetS score). (biomedcentral.com)
For both the standard- and no-glucose MetS-severity scores, scores were highest in the baseline-diabetes group, lowest in the never-diabetes group and intermediate in the incident-diabetes groups. (biomedcentral.com)
MetS severity appears to provide an estimate of metabolic disarray in the setting of diabetes and is predictive of future CHD events beyond HbA1c. (biomedcentral.com)
As such, it is unclear among individuals with diabetes whether assessing MetS severity would be an accurate means of tracking metabolic abnormalities over time and predicting future CHD. (biomedcentral.com)
For the standard five-component MetS-severity score, it is possible that extreme fluctuations in fasting glucose may unduly influence the overall calculated score, lowering its predictive power. (biomedcentral.com)
For the no-glucose score, it is possible that any CHD risk related to abnormalities in the other four MetS components would be inconsequential relative to the risk conferred by the degree of diabetes control. (biomedcentral.com)
It is now known that Central/Visceral Obesity with its Insulin Resistance and or Hyperinsulinemia is central in the pathogenesis of MetS. (kauveryhospital.com)
It is the pathophysiologic aspects of obesity coupled with MetS that leads to changes in hemodynamics, atherosclerosis and calcification, myocardial metabolism, microvascular dysfunction that culminates in myocardial infarction and heart failure. (kauveryhospital.com)

Of note, the USPSTF avoids the term "prediabetes" in favor of the more specific diagnoses of increased average blood glucose level, impaired fasting glucose (IFG), and impaired glucose tolerance (IGT). (acpinternist.org)
Central obesity is associated with insulin resistance.Theoretically, insulin resistance will cause impaired glucose tolerance (IGT) and could develop into type 2 diabetes. (ugm.ac.id)
Objective: To examine the prevalence of impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and increased glycated hemoglobin A1c (HbA1c) levels in US adolescents (aged 12-18 years) and young adults (aged 19-34 years) without diabetes. (cdc.gov)

People with this syndrome are at an increased risk of cardiovascular disease and type 2 diabetes mellitus. (bvsalud.org)
Hypoglycemia is a barrier to optimal glucose control in the treatment of both type 1 (T1DM) and type 2 diabetes mellitus (T2DM). (biomedcentral.com)
Few studies have reported the adherence to and efficacy of continuous glucose monitoring (CGM) for improving diabetes management in insulin-treated older adults with type 2 diabetes mellitus (T2DM). (biomedcentral.com)
Irisin plays a key role in metabolic diseases, including type 2 diabetes mellitus (T2DM). (biomedcentral.com)
Type 2 diabetes mellitus (T2D) is the type of diabetes that occurs later in life or with obesity at any age. (diabeteshealthmatters.com)
There are varying and similar presentations between patients with type 1 diabetes mellitus, type 2 diabetes mellitus, gestational diabetes, prediabetes, and glucose intolerance. (medscape.com)

38 In a multicentered, randomized controlled trial that studied the effects of periodontal treatment on secondary prevention of cardiovascular disease, Offenbacher et al 39 demonstrated that obesity may exert such a dominant influence that when obese individuals undergo periodontal therapy, its presence may nullify the effects of periodontal treatment on high-sensitivity C-reactive protein (hs-CRP), a sensitive marker of systemic inflammation. (dimensionsofdentalhygiene.com)
Thus, reports based on the survey-specific BMI percentiles would always designate 5 percent of children as obese and would fail to detect any true increasing prevalence of obesity across surveys. (nationalacademies.org)
Despite a modest body weight change relative to placebo-treated mice, GW-501516 treatment also improved diabetes as revealed by the decrease in blood glucose and blood insulin levels in genetically obese animals. (umbrellalabs.is)
It has been found that an increase in diacylglycerol species in insulin resistant obese and T2D subjects stimulates the secretion of insulin by the pancreas to maintain a normal glucose level ( 6 ). (frontiersin.org)
The western dietary pattern, obese-related anthropometric parameters, and most components of metabolic syndrome are positively associated with CRP levels and NLR in men and women with metabolic syndrome. (biomedcentral.com)
This study sought to evaluate the relationship between FGF21 and metabolic parameters in obese Korean children and adolescents. (jomes.org)
Fasting serum FGF21 and adiponectin levels as well as fasting insulin, glucose, transaminases, and lipid profiles were measured by enzyme-linked immunosorbent assays in 45 lean and 70 obese children aged 7-14 years. (jomes.org)
Obesity is a common finding in women with PCOS and between 40-80% of women with this condition are reported to be overweight or obese. (bodynhealth.org)
Although most treatments of obesity, with the exception of bariatric surgery, achieve modest reductions in weight and improvements in the PCOS phenotype, encouraging weight loss in the obese patient remains one of the front-line therapies. (bodynhealth.org)
Individuals who suffer from a condition called lipodystrophy, have little to no fat tissue (they look extremely athletic, with defined musculature) but display many of the metabolic symptoms thought to be exclusive to obese individuals. (scienceblogs.com)
Interestingly, numerous case studies have found excellent metabolic status (high insulin sensitivity, normal glucose tolerance, normal blood lipid levels and blood pressure) among these individuals despite their obviously obese state. (scienceblogs.com)
Outlier #4: Pharmacological treatment of unhealthy obese individuals leads to increased adiposity in concert with improvement in metabolic profiles. (scienceblogs.com)
Obese individuals with metabolic problems who are prescribed a class of drugs called thiazolidinediones or TZDs for short, actually grow more fat cells, get fatter, but also get healthier . (scienceblogs.com)
With the emerging era of obesity epidemic, more concerns are related to being obese than being short-statured in SGA children. (e-apem.org)

Polycystic ovarian syndrome (PCOS) is one of the most leading causes of female infertility, affecting 5-10% of women of reproductive age. (bodynhealth.org)
Weight gain is an important contributor (both genetic and environmental) in women with polycystic ovarian syndrome. (bodynhealth.org)

However, obesity does exacerbate many aspects of the phenotype, especially cardiovascular risk factors such as glucose intolerance and dyslipidemia. (bodynhealth.org)

Design, Setting, and Participants: This cross-sectional analyses of the 2005-2016 National Health and Nutrition Examination Survey assessed a population-based sample of adolescents and young adults who were not pregnant, did not have diabetes, and had measured fasting plasma glucose, 2-hour plasma glucose after a 75-g oral glucose tolerance test, and HbA1c levels. (cdc.gov)

Patients with higher-than-normal blood glucose levels are at increased risk for developing type 2 diabetes, cardiovascular disease, and stroke, according to the CDC. (acpinternist.org)
Metabolic syndrome is associated with the risk of developing cardiovascular disease and type 2 diabetes. (wikipedia.org)
25% body fat in men) may foretell the presence of metabolic disorders, or downstream precipitation of incident diabetes, cardiovascular disease, and other inflammatory-driven conditions. (dimensionsofdentalhygiene.com)
It is widely accepted as a major risk factor for metabolic and cardiovascular disease [ 2 ]. (biomedcentral.com)
Background and aims: The triglyceride (TG)/high-density lipoprotein-cholesterol (HDL-C) ratio has been reported as a useful marker of atherogenic lipid abnormalities, insulin resistance, and cardiovascular disease. (uniroma1.it)
Moreover, metabolic syndrome is one of the risk factors of cardiovascular disease (CVD). (biomedcentral.com)
Obesity is a well-established risk factor for coronary heart disease ence the relationship between waist circumference and CHD in (CHD) (1-4) and has been associated with higher rates of death at- race-sex subgroups by using data from the longitudinal cohort in tributable to cardiovascular disease (CVD) (5). (cdc.gov)

001). Although improved and persistent metabolic syndrome were both significantly associated with total WOMAC score, neither was significantly associated with knee pain after adjustment for age, sex, and BMI. (medscape.com)
however, this may vary significantly by age, dietary habits, gender, and even among participants with morbid obesity [ 9 ]. (hindawi.com)
ACE significantly reduced the body and peritoneal adipose tissue weights, serum lipid profiles (total cholesterol and triglycerides), glucose levels, hepatic lipid accumulation, and oxidative stress markers. (hindawi.com)
Clustering of metabolic abnormalities had significantly increased by increasing body mass index and waist circumferences, and with decreased HDL and elevated triglyceride. (itmedicalteam.pl)
The western dietary pattern, obesity, high body fat, high waist or hip circumference, and high waist-to-hip ratio were significantly associated with increased odds ratios of high CRP and NLR in both genders. (biomedcentral.com)
High systolic or diastolic blood pressure (BP), low high-density lipoprotein-cholesterol (HDL-C), high low-density lipoprotein-cholesterol (LDL-C), high total cholesterol (TC), high serum triglycerides (TG), and high fasting blood glucose (FBG) were significantly correlated with increased odds ratios of high CRP in both genders. (biomedcentral.com)
The pulmonary function test was not significantly affected by presence of metabolic syndrome. (biomedcentral.com)
The prevalence of metabolic syndrome was significantly lower in HAART and non-HAART users compared with NHANES participants unadjusted for body mass index (BMI). (natap.org)
Also, the microvascular tone and microvascular density are significantly impacted by obesity. (kauveryhospital.com)
Of 62 subjects, 14 of them have IGT and the prevalence of IGT was significantly higher in the central obesity group compared to non central obesity group (11/31 vs 3/31, p=0.03). (ugm.ac.id)

Intermittent fasting is one of the ways to boost your metabolism and keep your metabolic health. (healthifyme.com)
They have almost the same efficiency for improving lipid and glucose metabolism. (healthifyme.com)
Any abnormalities in metabolism can lead to metabolic syndrome. (healthifyme.com)
Blood pressure management in hypertensive patients with metabolic abnormalities is challenging, since many of the antihypertensive drugs adversely affect metabolism. (nih.gov)
Its pathophysiology is likely to involve insulin resistance at the level of both skeletal muscle and visceral adipose tissue and altered fluxes of metabolic substrates between these tissues that in turn impair liver metabolism. (erudit.org)
FGF21, a 210-amino-acid polypeptide hormone, is produced preferentially in the liver and regulates glucose and fat metabolism. (jomes.org)
According to thrifty phenotype hypothesis, an SGA fetus adapts to an adverse intrauterine environment to survive, and switches to permanent glucose-insulin metabolism [ 5 ]. (e-apem.org)

Central obesity is a key feature of the syndrome, as both a sign and a cause, in that the increasing adiposity often reflected in high waist circumference may both result from and contribute to insulin resistance. (wikipedia.org)
Diabetes mellitus was the most frequent component of metabolic syndrome in males, while low serum high-density lipoprotein cholesterol and high waist circumference ranked first and second in females. (who.int)
Subjects were stratified into tertiles of TG/HDL-C. There was a progressive increase in body mass index (BMI), BMI-SD score (SDS), waist circumference, blood pressure (BP), liver enzymes, glucose, insulin, homeostasis model assessment of insulin resistance, high-sensitivity C-reactive protein (hsCRP), and cIMT values across TG/HDL-C tertiles. (uniroma1.it)
Obesity defined by body mass index (BMI) and waist circumference was associated with inflammation [ 12 ]. (biomedcentral.com)
The new IDF consensus definition of the metabolic syndrome stipulates the following as a pre-requisite for a diagnosis of metabolic syndrome: ≥ 80 cm for European women ≥ 94 cm for European men Waist circumference is calculated by comfortably measuring the waist halfway between the bottom of the rib cage and the top of the pelvis. (slideplayer.com)
Central overweight and obesity in British youth aged 11-16 years: cross sectional surveys of waist circumference. (ugm.ac.id)

Our family medicine clinic is a hos- study period, the number of selected pital-affiliated clinic located in Jordan patients totalled 730 (281 males and The metabolic syndrome is a cluster- University Hospital (the main teaching 449 females). (who.int)

Raised triglycerides (at least 150 mg/dL) or specific treatment for this lipid abnormality. (medscape.com)
and a trend toward increased triglycerides, blood pressure, and glucose in the genetically susceptible. (wikipedia.org)
Good Metabolic Health is the absence of abnormalities in blood sugar levels, triglycerides, blood pressure levels and central obesity. (healthifyme.com)
Metabolic syndrome is defined by central obesity, increased systolic and diastolic blood pressure (BP), decreased high-density lipoprotein cholesterol (HDL-C), increased serum triglycerides (TG), and elevated fasting blood glucose (FBG). (biomedcentral.com)
Metabolic syndrome is mostly diagnosed through low HDL and high triglycerides in HIV. (natap.org)
Specific antiretroviral therapies are known to affect individual components of the metabolic syndrome adversely, such as increasing triglycerides (lopinavir/ritonavir,32 nevirapine,33 and nelfinavir33) and increasing fasting glucose (indinavir34 and lopinavir/ritonavir35). (natap.org)

This syndrome involves anovulation or ovulatory dysfunction and androgen excess of unclear etiology. (merckmanuals.com)
Abnormalities in intracellular Ca 2+ handling due to sub-cellular/receptor level dysfunction are implicated. (kauveryhospital.com)
Furthermore, the metabolic abnormalities associated with PCOS, such as β-cell dysfunction and type 2 diabetes, have heritable components in families of women with PCOS. (bodynhealth.org)
Finally, while I only discussed issues related to metabolic health, it is also proposed that the association between excess fat and other conditions such as osteoarthritis, sexual dysfunction, and cancer may also be more closely tied to the function rather than merely the amount of fat in one's body. (scienceblogs.com)

The pathogenic role played in the syndrome by the excessive expansion of adipose tissue occurring under sustained overeating, and its resulting lipotoxicity was reviewed by Vidal-Puig. (wikipedia.org)
Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. (ugm.ac.id)

Other signs of metabolic syndrome include high blood pressure, decreased fasting serum HDL cholesterol, elevated fasting serum triglyceride level, impaired fasting glucose, insulin resistance, or prediabetes. (wikipedia.org)
Dietary fiber, which is found in snow peas, is undoubtedly one of the most talked about nutrients for health promotion and disease prevention (The George Maternal Foundation, Dietary fibers promote beneficial physiological detects including location, bal cholesterol attenuation and blood glucose attenuation or a combination of the three effects. (directcurrentmusic.com)
Analysing the smoking habit influence on the IDFcriteria for the metabolic syndrome diagnosis we found that all thevariables show an increasing trend from light to heavy smokers, except forHDL cholesterol. (biomedcentral.com)
Other therapies have been associated with improvements in metabolic profiles, such as increases in HDL cholesterol (nevirapine and nelfinavir).33 In our cohort, lopinavir/ritonavir users had a higher risk of developing metabolic syndrome. (natap.org)
It is also used for obesity, altitude sickness, aging skin, high levels of cholesterol or other fats in the blood, and many other purposes, but there is no good scientific evidence to support many of these other uses. (medlineplus.gov)

Peripheral stigmata of lipid abnormalities and atherosclerosis, such as premature arcus cornealis, xanthelasma, eruptive (skin) xanthomata, tendon xanthomata, and lipemia retinalis, may be found in some patients. (medscape.com)

WNIN/GR-Ob rats with added glucose intolerance developed retinal degeneration similar to the parent line WNIN/Ob. (molvis.org)
Gestational diabetes is typically detected during routine screening of pregnant women for glucose intolerance. (medscape.com)
Any degree of glucose intolerance with onset or recognition during gestation places a patient in the category of gestational diabetes mellitus. (medscape.com)
Diagnosis of glucose intolerance may coincide with various patient conditions that may be complicated by glucose intolerance, such as liver cirrhosis, end-stage renal disease, and some rare genetic disorders. (medscape.com)
In addition to these important reproductive manifestations, PCOS has metabolic characteristics that include prominent defects in insulin action and β-cell function, defects that confer a substantially increased risk for glucose intolerance and type 2 diabetes. (bodynhealth.org)

Nigeria is a developing country that is currently witnessing an upsurge in diabetes mellitus and obesity with its antecedent consequences. (biomedcentral.com)

To quantify the accuracy of the HbA1c and fasting blood glucose tests, researchers assessed 49 studies of screening tests for prediabetes as part of a systematic review and meta-analysis published in January in The BMJ . (acpinternist.org)
Raised fasting blood glucose (at least 100 mg/dL) or previously diagnosed type 2 diabetes. (medscape.com)
Initially, this happens after meals - when glucose levels are at their highest and more insulin is needed - but eventually while fasting too (for example, upon waking in the morning). (diabeteshealthmatters.com)
Is Intermittent Fasting Linked To Metabolic Health? (healthifyme.com)
In most cases of IGT and impaired fasting glucose, the presence of 1 or more cardiovascular risk factors indicates the need for a screening test for disorders of glucose tolerance. (medscape.com)
Fasting glucose and 2 hours after loading were measured in all subjects. (ugm.ac.id)
Twenty one of the subjects were found to have impaired fasting glucose (IFG) (34%) and one subject (1.6 %) had IFG+IGT. (ugm.ac.id)
Fasting insulin levels and cardiometabolic risk factors across glycemic abnormality phenotypes were also compared. (cdc.gov)
Impaired fasting glucose constituted the largest proportion of prediabetes, with prevalence of 11.1% (95% CI, 9.5%-13.0%) in adolescents and 15.8% (95% CI, 14.0%-17.9%) in young adults. (cdc.gov)

There is debate regarding whether obesity or insulin resistance is the cause of the metabolic syndrome or if they are consequences of a more far-reaching metabolic derangement. (wikipedia.org)
The temporal profile is consequent to progression of the metabolic derangement, which is characterized by dehydration, electrolyte abnormalities, osmolality, and acid-base disturbances. (medscape.com)
Other clinical features, such as Kussmaul respiration and altered level of consciousness due to metabolic derangement, are commonly observed during acute deterioration. (medscape.com)
Conclusion: TG/HDL-C ratio may help identify children and adolescents at high risk for structural vascular changes and metabolic derangement. (uniroma1.it)

ABSTRACT This study assessed the prevalence of the metabolic syndrome, and its components, as defined by Adult Treatment Panel III criteria in Jordanian patients attending a family practice clinic for management of cardiovascular risk factors. (who.int)
ABSTRACT Metabolic syndrome is being reported more frequently in the Eastern Mediterranean region. (who.int)

In this study, the authors defined the role of peroxisome proliferator-activated receptor β/δ (PPARδ) in metabolic homeostasis by using subtype selective activators. (umbrellalabs.is)
Patients with impaired glucose homeostasis are generally asymptomatic. (medscape.com)
One interesting finding is that fibroblast growth factor 21 (FGF21) plays a central role in the maintenance of glucose and lipid homeostasis. (jomes.org)
These hormones regulate the body's growth, and are involved in cell to cell communication, control metabolic activity, sleep-wake homeostasis, and altered regulation or dysregulation of adaptive response in various physiologic and pathophysiologic states. (medscape.com)
In order to understand AD in DS and try to find ways to improve the qua- lity of life of these individuals, the understanding of these three conditions, DS, AD, and TH homeostasis, is central to finding better treatments and improving patient well-being. (bvsalud.org)

In this CPR, we discuss the management of obesity and metabolic syndrome (O&MS) in children and adolescents with CKD stages 2-5 and on dialysis, as well as after kidney transplantation, focusing on non-pharmacological treatment (diet, physical activity and behavior modification). (springer.com)
Therefore, FGF21 could be a biomarker for obesity-induced insulin resistance in children and adolescents as indicated in adults. (jomes.org)
Obesity in adolescents has become health problem in Indonesia. (ugm.ac.id)
Obesity was defined as having age- and sex-specific body mass index (calculated as weight in kilograms divided by height in meters squared) in the 95th percentile or higher in adolescents or 30 or higher in young adults. (cdc.gov)
Pediatric obesity remains an ongoing serious international health concern affecting ~17% of US children and adolescents, threatening their adult health and longevity. (medscape.com)
Adolescents undergoing lifestyle therapy, medication regimens, or bariatric surgery for obesity will need cohesive planning to help them effectively transition to adult care, with continued necessary monitoring, support, and intervention. (medscape.com)

Acquired or inherited defects associated to environmental factors in any part of this system can lead to metabolic disorders such as the syndrome X which is presently a frequent syndrome in industrialized countries. (erudit.org)

Most with metabolic syndrome (77%) had low HDL and hypertriglyceridemia plus ≥1 additional abnormality. (natap.org)

Metabolic syndrome can lead to several serious and chronic complications, including type-2 diabetes, cardiovascular diseases, stroke, kidney disease and nonalcoholic fatty liver disease. (wikipedia.org)
Childhood obesity is a significant health problem and associated with several metabolic and cardiovascular complications [ 6 - 8 ]. (itmedicalteam.pl)
Polycystic ovary syndrome has several significant potential complications. (merckmanuals.com)
Weight problems with symptoms of associated complications are the major features of morbid obesity . (symptoma.com)
Not only are patients with lipodystrophy at increased metabolic risk, but the severity of metabolic complications observed is closely related to the extent of their fat loss. (scienceblogs.com)
Early interventions, before and after birth, are needed for healthy catch-up growth to prevent later obesity and related complications. (e-apem.org)
Childhood obesity is an important public health concern because it is related to short-term and long-term complications. (e-apem.org)
This review summarizes the epidemiology and general risks associated with obesity in SGA children that are important to prevent obesity and its related complications. (e-apem.org)
screening for comorbidities of obesity should be applied in a hierarchal, logical manner for early identification before more serious complications result. (medscape.com)

Some researchers have noted that there is growing evidence of the influence of hyperglycaemia and hyper-insulinaemia which are key features of the metabolic syndrome on airway function and structure [ 7 ]. (biomedcentral.com)

Internists know to screen patients for diabetes, but even if blood glucose levels fall short, they may still need to provide a diagnosis and treatment. (acpinternist.org)
The groups add that unlike its diagnostic role in diabetes, HbA1c should be used only as a screening tool for prediabetes, requiring further glucose testing to make a definitive diagnosis. (acpinternist.org)
We present a 17 year-old woman, with a previous genetic diagnosis of Prader-Willi syndrome and BMI of 74 Kg/m(2), that was admitted in anasarca, with marked cyanosis, dyspnea and oliguria. (symptoma.com)
It is pertinent to note that the presence of obesity creates unique challenges for the diagnosis and treatment of asthma. (biomedcentral.com)
Obesity and PCOS: implications for diagnosis and treatment. (bodynhealth.org)

Epidemiological studies suggest that the prevalence and severity of obesity have increased to epidemic proportions worldwide, making it a global public health problem. (molvis.org)
Obesity and metabolic syndrome (O&MS) due to the worldwide obesity epidemic affects children at all stages of chronic kidney disease (CKD) including dialysis and after kidney transplantation. (springer.com)
There appears to be an epidemic of both obesity and polycystic ovary syndrome (PCOS) in the world today. (bodynhealth.org)

Studies showed that 65% of the world's population live in countries where overweight and obesity kills more people than underweight (World Health Organization, 2012). (directcurrentmusic.com)

Metabolic syndrome has become a serious health issue worldwide as the prevalence of obesity increases [ 1 ]. (hindawi.com)
The risk of having metabolic syndrome increases with age, affecting less than 10% of people in their 20's and 40% of people in their 60's. (itmedicalteam.pl)
Several studies show that smoking is associated withmetabolic abnormalities and increases the risk of Metabolic Syndrome. (biomedcentral.com)
There is growing epidemiological evidence that obesity increases the risk of developing asthma. (biomedcentral.com)
These results indicate that diet-induced obesity increases the risk of symptomatic features of osteoarthritis through changes in musculoskeletal function and pain-related behaviors. (biomedcentral.com)
however, there is currently no comprehensive explanation for why obesity increases the risk of osteoarthritis at different sites throughout the body. (biomedcentral.com)
Background: Metabolic syndrome increases the risk of cardiovascular outcomes and type II diabetes. (natap.org)

Previous studies have reported the therapeutic properties of A. iwayomogi on obesity, hyperlipidemia, and liver fibrosis [ 7 , 8 ]. (hindawi.com)
Therefore, we evaluated the effect of ACE on major manifestations of metabolic syndrome including obesity, hyperlipidemia, and fatty liver using a high-fat diet mouse model. (hindawi.com)

Theaim of this study was to estimate the prevalence of the metabolic syndromein a group of light and heavy smokers, wishing to give up smoking. (biomedcentral.com)

Some clinicians have even considered the term "prediabetes" to be a misnomer, as not all patients with elevated blood glucose levels go on to develop diabetes. (acpinternist.org)
Insulin resistance, metabolic syndrome, and prediabetes are closely related to one another and have overlapping aspects. (wikipedia.org)
Therefore, it is important to monitor the prevalence of prediabetes and varying levels of glucose tolerance to assess the future risk of type 2 diabetes in the youngest segment of the population. (cdc.gov)
The adjusted prevalence of prediabetes is higher in male individuals and in people with obesity. (cdc.gov)

Several studies have associated obesity with asthma particularly central obesity which is an important component of metabolic syndrome. (biomedcentral.com)

0.91) had a higher incidence of metabolic syndrome/diabetes than those in the low quotient group (25 vs. 8% p = 0.04). (frontiersin.org)
The incidence of metabolic syndrome in the NFHL study was higher with increasing viral load, higher BMI, higher trunk-to-limb fat ratio, and Kaletra (lopinavir/ritonavir) or didanosine (ddI) use and lower among college-educated persons. (natap.org)

The metabolic counterpart is excess lipolysis driving fatty acid levels, cathecholamine-induced peripheral, hepatic insulin resistance and fatty liver disease. (kauveryhospital.com)

In addition, if necessary, specific treatment of the metabolic disorders is required. (erudit.org)
This syndrome is associated with multiple metabolic alterations andhemodynamic disorders. (biomedcentral.com)
Obesity is also associated with infertility and menstrual irregularities, incontinence, and psychological disorders such as depression. (symptoma.com)
Although asthma and obesity, are two fast growing health problems of public health significance in developing countries, the relationship between these two disorders remains at best shrouded in mystery. (biomedcentral.com)

citation needed] Recent research indicates prolonged chronic stress can contribute to metabolic syndrome by disrupting the hormonal balance of the hypothalamic-pituitary-adrenal axis (HPA-axis). (wikipedia.org)
Diabetes is a complicated, chronic condition that requires ongoing medical attention as well as multiple risk-reduction measures beyond glucose control. (biomedcentral.com)
There is a strong rationale for implementing a risk assessment model that considers patients' cumulative inflammatory burden, which may be amplified by obesity and chronic infection from periodontal disease. (dimensionsofdentalhygiene.com)
We excluded participants with diabetes, metabolic syndrome, chronic diseases, and those who had changed food habits in the previous 3 months. (frontiersin.org)
Under chronic hyperinsulinemia, FA oxidation progressively decreases with a consequent alteration in glucose transport, and/or phosphorylation pathways associated with normal glucose uptake ( 5 ). (frontiersin.org)
In contrast, the relation between increasing viral load and metabolic syndrome does not seem to be mediated by general inflammation caused by chronic infection for 2 reasons. (natap.org)
As a consequence, there has also been a marked increase in the prevalence of type 2 diabetes all over the world and this chronic metabolic disease is now considered as a coronary heart disease risk equivalent. (researchgate.net)
Obesity Obesity is a chronic, multifactorial, relapsing disorder characterized by excess body weight and defined as a body mass index (BMI) of ≥ 30 kg/m2. (msdmanuals.com)
Brand new research published in the last few weeks reveals important information for people with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) and Fibromyalgia (FM). (wellnessresources.com)

If merely the amount of excess fat is the direct cause of metabolic dysregulation then removing that fat through surgery should obviously result in metabolic improvement. (scienceblogs.com)

In individuals who will ultimately develop type 2 diabetes, it has been shown that blood glucose and insulin levels are normal for many years, until at some point in time, insulin resistance develops. (diabeteshealthmatters.com)

A special form was used for vated blood glucose [1]. (who.int)
Internists know to screen patients for diabetes, but may be unsure how to manage patients whose blood glucose levels are higher than normal but fall below the cutoff of the disease. (acpinternist.org)
Blood glucose monitoring is essential in diabetes management. (biomedcentral.com)
In traditional Korean medicine (TKM) and traditional Chinese medicine (TCM), metabolic abnormalities are considered indicative of " dampness/phlegm " ( 濕痰 ) and " blood stasis " ( 瘀血 ) [ 6 ]. (hindawi.com)
One action of insulin is to cause the body's cells (particularly the muscle and fat) to remove and use glucose from the blood. (diabeteshealthmatters.com)
This is one way by which insulin controls the level of glucose in blood. (diabeteshealthmatters.com)
As long as the pancreas is able to produce enough insulin to overcome this resistance, blood glucose levels remain normal. (diabeteshealthmatters.com)
When the pancreas can no longer produce enough insulin, the blood glucose levels begin to rise. (diabeteshealthmatters.com)
When in doubt, it is good to wear a wearable device, like the HealthifyPRO 2.0 BIOS, which will help track blood glucose levels in real-time. (healthifyme.com)
And I am haunted by the memory of my pharmacist whom I had known for many years when he sold me my first blood glucose meter. (thenutritiondebate.com)

The key sign of metabolic syndrome is central obesity, also known as visceral, male-pattern or apple-shaped adiposity. (wikipedia.org)
Rather than total adiposity, the core clinical component of the syndrome is visceral and/or ectopic fat (i.e., fat in organs not designed for fat storage) whereas the principal metabolic abnormality is insulin resistance. (wikipedia.org)
A patient may have central adiposity in spite of a normal BMI. (medscape.com)
The mechanisms by which obesity influences the structural or symptomatic features of osteoarthritis are not well understood, but may include systemic inflammation associated with increased adiposity. (biomedcentral.com)
however, growth hormone-insulin-like growth factor axis disturbance by fetal programming and accelerated postnatal weight gain contributed to central adiposity in SGA children. (e-apem.org)
Central adiposity and coronary heart disease (CHD) are influenced by indi- vidual and neighborhood characteristics, but it is unknown if the relation- ship between central obesity and development of CHD is influenced by Results these factors. (cdc.gov)

However, warning signs of metabolic syndrome can appear during childhood [ 3 ]. (itmedicalteam.pl)

Research shows that Western diet habits are a factor in development of metabolic syndrome, with high consumption of food that is not biochemically suited to humans. (wikipedia.org)
First, high viral load did not predict development of metabolic syndrome. (natap.org)

To supplement existing evidence on the association between metabolic syndrome and joint pain in older adults, the researchers investigated the association in middle-aged adults over a 10- to 13-year period. (medscape.com)
There was no association between metabolic syndrome and indinavir, nelfinavir, or nevirapine in our study. (natap.org)

A previous cohort study reported a strong relationship between metabolic syndrome and an increased risk of mortality [ 2 ]. (hindawi.com)

We will also summarize the available clinical evidence regarding the metabolic effects of beta-blockers in hypertensive patients, with an emphasis on nebivolol. (nih.gov)
Polycystic ovary syndrome is a clinical syndrome typically characterized by anovulation or oligo-ovulation, signs of androgen excess (eg, hirsutism, acne), and multiple ovarian cysts in the ovaries. (merckmanuals.com)
PCOS is usually defined as a clinical syndrome, not by the presence of ovarian cysts. (merckmanuals.com)
Central obesity is a risk factor for development of diabetes, heart disease and when present in a woman with PCOS worsens the clinical features of the syndrome. (bodynhealth.org)
To formulate clinical practice guidelines for the assessment, treatment, and prevention of pediatric obesity. (medscape.com)

Freemark M. Metabolic consequences of obesity and their management. (ugm.ac.id)

2000) (see Chapter 3 for a more extensive discussion about the use of terms for childhood overweight and childhood obesity). (nationalacademies.org)
In 2000, obesity was two to three times more common in children and youth than in a reference period in the early 1970s. (nationalacademies.org)
Objective: To determine the incidence and risk factors for metabolic syndrome in HIV-infected adults in the Nutrition for Healthy Living (NFHL) study (2000-2003) and prevalence relative to the findings of the National Health and Nutrition Examination Survey (NHANES) (1999-2002). (natap.org)

High susceptibility to dietary obesity was associated with increased osteoarthritic changes in the knee and impaired musculoskeletal force generation and motor function compared with controls. (biomedcentral.com)

The application of WHtR provides an alternative anthropometric index of central obesity that avoids the limitations of WC because the inclusion of height into the index enhances the avoidance of any potential confounding of cardiometabolic risk by height [ 19 ]. (hindawi.com)
In the short-term anthropometric measurements and their variation overtime were not correlated with metabolic syndrome/diabetes. (frontiersin.org)
The objective of the study was to determine the association of dietary patterns, anthropometric measurements, and metabolic parameters with inflammatory markers in middle-aged and older adults with metabolic syndrome in Taiwan. (biomedcentral.com)
Multivariate logistic regression was performed to evaluate the association of dietary patterns, anthropometric measurements, and metabolic parameters with C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR) in men and women with metabolic syndrome. (biomedcentral.com)
p90) and non central obesity based on anthropometric data. (ugm.ac.id)

Anatomy16

Organisms8

Diseases64

Chemicals and Drugs55

Analytical, Diagnostic and Therapeutic Techniques and Equipment58

Psychiatry and Psychology7

Phenomena and Processes54

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture5

Information Science3

Named Groups4

Health Care35

Geographicals11

Hypertension29

Abdominal10

MetS20

Impaired glucose t3

Type 2 diabet6

Obese14

Polycystic ovarian2

Dyslipidemia1

Plasma glucose1

Cardiovascular disease7

Significantly10

Metabolism7

Circumference6

Cluster1

Triglycerides6

Dysfunction4

Adipose tissue2

Cholesterol5

Lipid abnormalities1

Intolerance5

Diabetes mellitus1

Fasting9

Derangement4

Abstract2

Homeostasis5

Adolescents6

Lead to metabolic1

Hypertriglyceridemia1

Complications9

Features of the metabolic syndrome1

Diagnosis5

Epidemic3

Overweight and obesity1

Increases7

Hyperlipidemia2

Prevalence of the metabolic1

Prediabetes4

Component of metabolic syndrome1

Incidence of metabolic syndrome2

Liver1

Disorders4

Chronic9

Dysregulation1

Insulin levels1

Blood10

Adiposity6

Signs of metabolic syndrome1

Development of metabolic syndrome2

Association between metabolic syndrome2

Relationship between metabolic syndrome1

Clinical5

Consequences of obesity1

20003

Susceptibility1

Anthropometric5