• A general mesoderm-inducing signal from the vegetal hemisphere induces overlying marginal zone cells to become ventral mesoderm. (ucalgary.ca)
  • The mesoderm moves to the midline until it covers the notochord, when the mesoderm cells proliferate they form the paraxial mesoderm. (wikipedia.org)
  • They are functionally redundant in the sense that mice deficient for either Nck1 or Nck2 are viable, whereas inactivation of both Nck1 and Nck2 results in profound defects in mesoderm-derived notochord and embryonic lethality at embryonic day 9.5. (asm.org)
  • As an example, true flies use at least two different mechanisms to make the middle germ layer (the mesoderm). (elifesciences.org)
  • In both cases, the mesoderm is made up of cells that move inwards from the boundary of the outer germ layer. (elifesciences.org)
  • The mesoderm is the middle germ layer. (sdbcore.org)
  • The mesoderm is the germ layer that forms many muscles, the circulatory and excretory systems, and the dermis, skeleton, and other supportive and connective tissue. (thefreedictionary.com)
  • In other deuterostomes (reptiles, birds, and mammals), because of secondary changes in the process of germlayer individuation, the mesodermal rudiment becomes part of the primitive ectodermal layer during the blastula stage and later becomes a third germ layer, the mesoderm. (thefreedictionary.com)
  • Here, we delineate a logical model encompassing 48 components and 82 regulatory interactions involved in mesoderm specification during Drosophila development, thereby providing a formal integration of all available genetic information from the literature. (plos.org)
  • We delineate a logical model encompassing 48 components and 82 regulatory interactions controlling mesoderm specification during Drosophila development, thereby integrating all major genetic processes underlying the formation of four mesodermal tissues. (plos.org)
  • This modelling study is the first to tackle the regulatory network controlling the specification of mesoderm during Drosophila development, and more broadly deals with one of the most comprehensive developmental networks that have been modelled to date. (plos.org)
  • The Drosophila fibroblast growth factor (FGF) receptors Heartless and Breathless are required for the morphogenesis of the mesoderm and the tracheal system. (royalsocietypublishing.org)
  • Both genes are expressed and required for mesoderm invagination in the fruit fly Drosophila melanogaster but do not appear during mesoderm ingression of the midge Chironomus riparius . (elifesciences.org)
  • Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm. (uchicago.edu)
  • Xu X, Yin Z, Hudson JB, Ferguson EL, Frasch M. Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm. (uchicago.edu)
  • However, elongation of axial mesoderm must be also coordinated with the pattern of AP tissue specification to generate a normal larval morphology. (nih.gov)
  • We present evidence that classical TGFbeta-induced growth inhibition was probably the cause of insufficient mesoderm being available for paraxial and axial structures. (uniprot.org)
  • Positioned on either side of the axial mesoderm. (studentreader.com)
  • A network of embryonic genes, many of which are expressed in the mesoderm and the organiser, can initiate transcription through a non-canonical mechanism. (biologists.org)
  • In this paper we show that these genes also control mesoderm development. (nih.gov)
  • We propose that the signal produced by the neurogenic genes is a general one, effective in both ectoderm and mesoderm. (nih.gov)
  • We demonstrate that early expression of either or both of these genes in C.riparius is sufficient to invoke mesoderm invagination similar to D.melanogaster . (elifesciences.org)
  • Fruit flies and midges shared their last common ancestor 250 million years ago and although the genes that make the mesoderm in fruit flies are well understood, little is known about how the mesoderm forms in midges. (elifesciences.org)
  • The messengers encoding the BMPs are not localized in the vegetal hemisphere, which casts some doubt on their role in mesoderm induction. (ucalgary.ca)
  • a measure of the start of animal cap competence to form mesoderm. (springer.com)
  • Ohata E., Takahashi Y. (2009) In Ovo Electroporation for Targeting the Somitic Mesoderm. (springer.com)
  • Prechordal plate - lies above the buccopharyngeal membrane and is the cardiogenic mesoderm, that will form the heart. (edu.au)