The outermost extra-embryonic membrane surrounding the developing embryo. (rush.edu)
Through the definition of a coordinate system based on mesh structure and the development of a special sectioning procedure, sections can be localized within the intact embryo and three-dimensional coordinates given to any element of embryo volume. (sciencegate.app)
Genes that determine the fate of a cell or CELLS in a region of the embryo during EMBRYONIC DEVELOPMENT. (ouhsc.edu)
Neoplasms composed of primordial GERM CELLS of embryonic GONADS or of elements of the germ layers of the EMBRYO, MAMMALIAN. (sdsu.edu)
The carefully timed migration of groups of embryonic stem cells produces distinct layers of the embryo that are further shaped and folded into structures such as the neural tube, which gives rise to the spinal cord and brain. (nih.gov)
Stem Cells7
We present a novel and efficient non-integrating gene expression system in human embryonic stem cells (hESc) utilizing human artificial chromosomes (HAC), which behave as autonomous endogenous host chromosomes and segregate correctly during cell division. (nih.gov)
Human cortical organoids (hCOs), derived from human embryonic stem cells (hESCs), provide a platform to study human brain development and diseases in complex three-dimensional tissue. (nih.gov)
In addition, autologous CSCs can be employed without the ethical and immunological problems associated with the use of embryonic stem cells. (derstandard.at)
So we decided to use these stem cells in association with an artificial, netlike matrix to support formation of functional tissue-like structures that can be used in a new therapeutic approach to repair the heart. (derstandard.at)
Using a hybrid therapy that incorporates tissue engineering, we seeded a biodegradable mesh with cardiac stem cells. (derstandard.at)
Cai J, Donaldson A, Yang M, German MS, Enikolopov G, Iacovitti L. The role of Lmx1a in the differentiation of human embryonic stem cells into midbrain dopamine neurons in culture and after transplantation into a Parkinson's disease model. (jefferson.edu)
In 2005, he wrote an essay in Nature challenging the importance of "cell theory"-a concept that holds cells as the basic structure of all organisms, and in 2001, he published a paper finding that adult stem cells could be made to act similarly to embryonic cells. (nationalgeographic.com)
Medical Subject3
Wolffian Ducts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
The following is a list of the codes for MeSH (Medical Subject Headings), a comprehensive controlled vocabulary for the purpose of indexing journal articles and books in the life sciences. (wikipedia.org)
Branchial Region" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (wakehealth.edu)
Cells15
The mesh acted as a scaffold on which the stems cells were grown into morphologically recognizable cardiac tissue. (derstandard.at)
A microtubule-associated protein that is primarily found in neuronal precursor cells and immature NEURONS in embryonic and adult cortical structures. (bvsalud.org)
In this study, we have analysed the dynamics of H3K27me3 at pericentromeric heterochromatin (PCH) during development of the mouse blastocyst, in comparison with cultured embryonic cells. (sciencegate.app)
We also conclude that the non-canonical presence of H3K27me3 at PCH is a defining feature of embryonic cells in the young blastocyst before epiblast segregation. (sciencegate.app)
The developmental potential within pluripotent cells in the canonical model is restricted to embryonic tissues, whereas totipotent cells can differentiate into both embryonic and extraembryonic tissues. (sciencegate.app)
To address this question, single-cell RNA sequencing was applied to TBLCs and cells from early mouse embryonic developmental stages and the data were integrated using canonical correlation analyses. (sciencegate.app)
Remarkably, a subpopulation within the TBLCs population expressed a high level of the totipotent-related genes Zscan4s and displayed transcriptomic features similar to mouse two-cell stage embryonic cells. (sciencegate.app)
T6081The Stable Bcl-xL Mouse Embryonic Fibroblast Cell Line was derived from primary embryonic cells from an 11-d-pregnant Bcl-x. (topsan.org)
RbmA helps cells to stick together and to form clusters, while VPS is needed to develop a three-dimensional cellular structure. (elifesciences.org)
Much research focuses on developing a synthetic substrate in order to transplant healthy cells to the native Bruch's membrane (BM), however, the diseased native BM and related structures still leave potential for transplanted cells to succumb to disease. (frontiersin.org)
This could allow this novel bioactive substrate to be a potential treatment for atrophic AMD that would function two-fold: deliver the required monolayer of healthy RPE cells to the macula on a synthetic BM and remove diseased structures within the retina, restoring the waste/exchange pathway and preventing vision loss. (frontiersin.org)
The underlying native diseased BM and related structures remain, however, which leaves the potential for healthy transplanted cells to eventually succumb to disease ( White and Olabisi, 2017 ). (frontiersin.org)
Two C. elegans cells (blue) migrate from an embryo's surface (top) to its interior (bottom), where the cells will form internal structures. (nih.gov)
Like choreographed dancers, cells move in a coordinated manner to help form tissues, organs and limbs during embryonic development. (nih.gov)
In one stage of development, certain cells migrate from the embryo's surface to its interior to form internal structures. (nih.gov)
Notochord2
In the higher vertebrates, notochord is a transient structure, and segments of the vertebral column will develop around it. (ucdenver.edu)
Furthermore, boz is essential for specification of dorsoanterior embryonic structures, including notochord, prechordal mesendoderm, floor plate and forebrain. (zfin.org)
Developmental2
The TBLCs exhibited totipotency transcriptionally and acquired expanded developmental potential with the ability to yield various embryonic and extraembryonic tissues that may be employed as novel mouse developmental cell models. (sciencegate.app)
Around the 12th week of gestation, the processus vaginalis forms, which is an embryonic developmental outpouching of the peritoneum. (medscape.com)
Development4
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. (umassmed.edu)
The matrix is essential for early embryonic development and it regulates nearly every facet of cell behaviour. (biologists.com)
Both genes code for ciliary or centriolar proteins that seem to be involved in early embryonic development of the midline. (orpha.net)
Overexpression of boz in the extraembryonic yolk syncytial layer of boz mutant embryos is sufficient for normal development of the overlying blastoderm, revealing an involvement of extraembryonic structures in anterior patterning in fish similarly to murine embryos. (zfin.org)
Genome2
In situ genome sequencing resolves DNA sequence and structure in intact biological samples. (cngb.org)
Using these data, we characterized parent-specific changes in genome structure across embryonic stages, revealed single-cell chromatin domains in zygotes, and uncovered epigenetic memory of global chromosome positioning within individual embryos. (cngb.org)
Indexing1
Subheadings (or qualifiers) are used in indexing to qualify MeSH headings by pinpointing some specific aspects of the concept represented by the heading, e.g. (who.int)
Stages2
Differential expression analyses were performed between TBLCs and multi-embryonic cell stages to identify differentially expressed genes. (sciencegate.app)
We demonstrate that the zebrafish bozozok (boz) locus is required at the blastula stages for formation of the embryonic shield, the equivalent of the gastrula organizer and expression of multiple organizer-specific genes. (zfin.org)
Connective tissue2
A tumor consisting of displaced ectodermal structures along the lines of embryonic fusion, the wall being formed of epithelium-lined connective tissue, including skin appendages, and containing keratin, sebum, and hair. (nih.gov)
ECMs range from pericellular matrices, such as basement membranes, to the grander structures of connective tissue that give organs their shape, and the tendons, cartilage and bones that bestow humans and animals with their form. (biologists.com)
Embryos2
The use of a mesh system allows identification of individual embryos by position, and control of their orientation during culture and preparation for light and electron microscopy. (sciencegate.app)
T6080The Stable Bcl-x Knockout Mouse Embryonic Fibroblast Cell Line was generated from embryos of a pregnant mouse heterozygous for. (topsan.org)
Gene expression1
Patterns of Crystallin Gene Expression in Differentiation State Specific Regions of the Embryonic Chicken Lens. (jefferson.edu)
PROTEIN1
Scientists used to think this migration began as soon as a 'motor protein' called myosin started up and tugged on a mesh of filaments just under the cell surface, causing the surface to shrink and pinch inward. (nih.gov)
Descriptors1
Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. (harvard.edu)
Brain4
These vhCOs form vasculature-like structures that resemble the vasculature in early prenatal brain, and they present a robust model to study brain disease in vitro. (nih.gov)
The middle of the three primitive cerebral vesicles of the embryonic brain. (jefferson.edu)
Brain abnormalities include hydrocephaly and agenesis of midline structures such as corpus callosum, cerebellar vermis and septum pellucidum, leading to a wide opened fluid-filled space between lateral ventricles. (orpha.net)
Ultrasound scan during pregnancy often reveals hydrocephaly and an abnormal structure of the brain. (orpha.net)
Distinct1
These bits of information suggest that will Zein-SCHP videos can be used as a functioning foods the labels material along with antioxidant properties.Connection in between biopolymers produces distinct rheological behaviors, which may be powerful on the structure associated with food items. (pparpathway.com)
Remarkably1
Despite some loss of material along an oblique crack, most of the internal structures are remarkably preserved, and most of the missing structures can be reconstructed by symmetry. (plos.org)
GROWTH1
Telomere length predicts individual lifespan and in this study we investigated whether embryonic growth rate, manipulated using incubation temperature, affects erythrocyte telomere length in a wild bird species, the common tern ( Sterna hirundo ). (biologists.com)
Migration1
A cell's ECM coat provides the architectural hardware for cell positioning and migration, which is meshed together with intracellular cytoskeletal networks by myriad components of the adhesome. (biologists.com)
Higher vertebrates2
In higher vertebrates, Wolffian ducts persist in the male forming VAS DEFERENS, but atrophy into vestigial structures in the female. (harvard.edu)
In higher vertebrates, the arches forms outpouchings and develop into structures of the head and neck. (wakehealth.edu)
Organization1
HAC are important vectors for investigating the organization and structure of the kinetochore, and gene complementation. (nih.gov)
Functional1
Importantly, the presence of vasculature-like structures resulted in enhanced functional maturation of organoids. (nih.gov)
Organisms2
These results demonstrate how IGS can directly connect sequence and structure across length scales from single base pairs to whole organisms. (cngb.org)
As single-celled organisms bacteria are exposed to a variety of stresses, but their ability to form multicellular structures called biofilms helps them to grow and survive in challenging environments. (elifesciences.org)
Cell Line2
88 TAg Stable Y-LIZ DNA Polymerase-β Knockout Mouse Embryonic Fibroblast Cell Line carries the lambda-LIZ transgene (Y-LIZ), a shuttle vector which enables for mutation analysis. (topsan.org)
T316992 TAg Stable Y-LIZ Wildtype Mouse Embryonic Fibroblast Cell Line carry the lambda-LIZ transgene (Y-LIZ), a shuttle. (topsan.org)
Develop1
They develop from embryonic progenitor domain V1.Ia inhibitory interneurons which also originate from V1 are responsible for reciprocal inhibition of MOTONEURONS. (uchicago.edu)
Simultaneously1
However, it is still unclear how these matrix proteins interact to simultaneously remain a connected and flexible multicellular structure. (elifesciences.org)
Components1
demonstrated that far from being inert, the matrix components are dynamic structures that interact with each other to maintain the biofilm architecture. (elifesciences.org)
Matrix2
C ) An RbmA dimer can bind to several strands of VPS to create a stable mesh across the matrix. (elifesciences.org)
genetically modified RbmA to only form dimers, the proteins concentrated in the center of the matrix instead of building a stable mesh across it. (elifesciences.org)
Identify1
This virtual approach offers the possibility to connect with certainty all the external foramina to the blood and nerve canals and the central structures, and thus identify accurate homologies without destroying the specimen. (plos.org)
Forms1
This process of testicular decent is assisted by a structure known as the gubernaculum, which forms on the inferior aspect of the gonad and signals descent and ultimately adherence of the gonad in its final destination. (medscape.com)
Animals1
Using this technique in animals, the researchers have observed an increase in physiological functions such as the cardiac ejection fraction - a measure of the efficacy of the heart's contraction - and an improvement of cardiac chamber volumes following the placement of these tissue structures on the surface of the animal's damaged hearts. (derstandard.at)