Glomerular MesangiumMesangial CellsKidney GlomerulusGlomerulonephritis, IGAGlomerulonephritisGlomerulonephritis, MembranoproliferativeCells, CulturedDiabetic NephropathiesProteinuriaKidneyAntigens, Thy-1Immunoglobulin ABasement MembraneAntigen-Antibody ComplexNephritisGlomerulosclerosis, Focal SegmentalFluorescent Antibody TechniqueImmune Complex DiseasesJuxtaglomerular ApparatusRats, Sprague-DawleyRNA, MessengerFibronectinsPurpura, Schoenlein-HenochCell DivisionExtracellular MatrixKidney DiseasesMicroscopy, ElectronTransforming Growth Factor betaCollagenPlatelet-Derived Growth FactorCollagen Type IVGene ExpressionTransforming Growth Factor beta1Immunoglobulin GComplement C3CapillariesBiopsyComplement System ProteinsInterleukin-1ImmunohistochemistryGlucoseKidney TubulesRats, Inbred StrainsProtein Kinase CAngiotensin IIEnzyme ActivationDisease Models, AnimalHypertrophyPodocytesMitogen-Activated Protein KinasesConnective Tissue Growth FactorSignal TransductionEnzyme InhibitorsExtracellular Matrix ProteinsDiabetes Mellitus, ExperimentalPhospholipases ARats, WistarPhosphorylationPhospholipases A2Immunoglobulin MDose-Response Relationship, DrugThymidineGene Expression RegulationChemokine CCL2Blotting, WesternIsoantibodiesUp-RegulationBlotting, NorthernProto-Oncogene Proteins c-sisNeutral CeramidaseDinoprostoneGroup II Phospholipases A2EndothelinsDNAIntercellular Signaling Peptides and ProteinsLupus NephritisIsoenzymesTrimeresurusEndothelin-1Nitric OxideIntegrin alpha1beta1Mitogen-Activated Protein Kinase 1ActinsNitric Oxide SynthaseApoptosisCollagen Type INephrotic SyndromeReverse Transcriptase Polymerase Chain ReactionReactive Oxygen SpeciesImmediate-Early ProteinsHyperglycemiaAntibodiesCulture Media, ConditionedPurinergic AgonistsNF-kappa BTetradecanoylphorbol AcetatePlasminogen Activator Inhibitor 1Tumor Necrosis Factor-alphaCell LineMitogen-Activated Protein Kinase 13