• In many cases, because meningiomas do not cause any noticeable signs or symptoms, they are only discovered as a result of imaging scans done for reasons that turn out to be unrelated to the tumor, such as a head injury, stroke or headaches. (mayoclinic.org)
  • When symptoms do develop they may vary depending on the location and size of the meningioma and include headaches, vision changes and difficulty hearing. (wisegeek.com)
  • The recurrence rate for partially removed meningiomas is higher. (ucdenver.edu)
  • Dr Bárbara Meléndez and her colleagues in the Unidad de Investigación de Patología Molecular (Molecular Pathology Research Unit) at Hospital Virgen de la Salud in Toledo, Spain, are using Qlucore Omics Explorer to investigate how generally benign meningiomas can start to exhibit the sort of histology and recurrence usually associated with more aggressive tumours. (scientific-computing.com)
  • The DNA methylation-based meningioma classification published in 2017 used DNA copy number analysis, mutation profiling, and RNA sequencing to distinguish six clinically relevant methylation classes, which contributed to a better prediction of tumor recurrence and prognosis. (frontiersin.org)
  • Recurrence of meningiomas versus proliferating cell nuclear antigen (PCNA) positivity and AgNOR counting. (nih.gov)
  • The classic monograph on meningiomas by Cushing and Eisenhardt presents nine major types and twenty subtypes. (scielo.br)
  • The research has led to a discovery, as Meléndez explained: 'Expression analyses allowed us to identify that meningiomas can be classified into an aggressive and a non-aggressive group - despite WHO classification criteria establishing three malignancy groups and about 15 histopathological subtypes. (scientific-computing.com)
  • Meningiomas were originally classified into 9 major subtypes based on their structure and form. (brighamandwomens.org)
  • According to the World Health Organization (WHO) grading, meningioma is classified into 15 subtypes with three grades of malignancy. (frontiersin.org)
  • Christiaans I, Kenter SB, Brink HC, van Os TA, Baas F, van den Munckhof P, Kidd AM, Hulsebos TJ (2010) Germline SMARCB1 mutation and somatic NF2 mutations in familial multiple meningiomas. (springer.com)
  • Evans DG, Watson C, King A, Wallace AJ, Baser ME (2005) Multiple meningiomas: differential involvement of the NF2 gene in children and adults. (springer.com)
  • Multiple meningiomas may develop. (merckmanuals.com)
  • CyberKnife was invented at Stanford and treats a variety of conditions, including meningiomas, with high-dose radiation therapy. (stanford.edu)
  • Radiation therapy that involves radiation to the head may increase the risk of a meningioma. (mayoclinic.org)
  • In this study, the authors evaluated the outcomes of parasellar and sellar meningiomas managed with Gamma Knife radiosurgery (GKRS) both as an adjunct to microsurgical removal or conventional radiation therapy and as a primary treatment modality. (thejns.org)
  • Some meningiomas respond best to radiation therapy alone, including highly precise stereotactic radiosurgery. (nyp.org)
  • In one series, less than one-third of clinoidal meningiomas could be completely resected without unacceptable risk of damaging of blood vessels (especially the carotid artery) or cranial nerves, risks that are lower with radiosurgery. (wikipedia.org)
  • Middle-aged women are more likely to develop meningioma than men, and it is very rare in children. (apollohospitals.com)
  • Individuals who reported receiving bitewing exams on a yearly or more frequent basis were 1.4 to 1.9 times as likely to develop meningioma as controls. (science20.com)
  • Those who reported receiving them on a yearly or more frequent basis were 2.7 to 3.0 times (depending on age) as likely to develop meningioma as controls. (science20.com)
  • Meningiomas , as defined by the World Health Organization (WHO), are "meningothelial (arachnoid) cell neoplasms, typically attached to the inner surface of the dura mater," and these tumors fall into WHO grades I, II, and III. (medscape.com)
  • MRI with gadolinium contrast ( Figure 1C ) showed extensive enhancement and adjacent thickening of the surrounding dura concerning for meningioma. (omicsonline.org)
  • So most people with a meningioma walk around for years without knowing they have one. (readthehook.com)
  • Shaftel SS et al (2017) Intraosseous meningioma mimicking fibrous dysplasia. (springer.com)
  • Boston, MA -- ( SBWIRE ) -- 07/11/2017 -- Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Meningioma - Pipeline Review, H1 2017, provides an overview of the Meningioma (Oncology) pipeline landscape. (sbwire.com)
  • Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Meningioma - Pipeline Review, H1 2017, provides comprehensive information on the therapeutics under development for Meningioma (Oncology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. (sbwire.com)