• Leptomeningeal metastasis from systemic cancer: review and update on management. (prodiagnosis.org)
  • Recently, STAT6 has received considerable attention in the area of tumor growth and metastasis. (biocare.net)
  • The association of OS with age, performance status, T factor (mean tumor size according to the tumor-node-metastasis [TNM] grading system), N factor (mean lymph node involvement according to the TNM grading system), and treatment method was assessed. (brieflands.com)
  • Maxillary sinus tumors often advance locally without lymph node metastasis due to limited lymphatic drainage ( 6 ). (brieflands.com)
  • Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms . (lookformedical.com)
  • Note: Patients with stable brain or subdural metastases are allowed if the patient has completed local therapy and was on a stable or decreasing dose of corticosteroids at baseline for management of brain metastasis for at least 4 weeks before starting treatment in this study. (ucsf.edu)
  • Inhibition of polyamine by DFMO in animal experiments reduced tumor growth and decreased the amount of metastasis, resulting in prolonged survival of the animals.ix With the introduction of the present "Intume Oxidant," polyamine synthesis will be halted by ClO2 oxidation of existing PA, along with oxidation of PA precursor molecules, arginine and ornithine. (justia.com)
  • Cerebellopontine Angle Tumors. (archivosdeneurociencias.org)
  • With certain anatomic locations, other differential diagnoses should be considered, including vestibular schwannoma for cerebellopontine angle tumors, pituitary macroadenoma and craniopharyngioma for parasellar tumors, and chordoma/chondrosarcoma for masses around the clivus. (medscape.com)
  • Meningiomas are the most commonly reported intracranial tumor. (medscape.com)
  • They represent approximately 38% of all intracranial neoplasms in females and 20% in males. (medscape.com)
  • Central nervous system SFT represents only 0.09% of tumors occurring on the meninges, while intracranial solitary fibrous tumors (ISFT) are even more rare. (bvsalud.org)
  • We reported a case of a 60-year-old female with an intracranial solitary fibrous tumor (ISFT). (bvsalud.org)
  • Intracranial ES/pPNET is rare tumor with nonspecific clinical presentation and radiological findings. (surgicalneurologyint.com)
  • CT was quickly shown to be of value for the intracranial diagnosis and evaluation of primary tumors of the brain and surrounding structures. (ajnr.org)
  • Meningioma, also known as meningeal tumor, is typically a slow-growing tumor that forms from the meninges, the membranous layers surrounding the brain and spinal cord. (wikipedia.org)
  • Due to its rarity and similarities with meningioma, ISFT is often misdiagnosed as other types of brain tumors. (bvsalud.org)
  • At the UCSF Brain Tumor Center, Raleigh is a principal investigator with the Wolfe Meningioma Program Project. (ucsf.edu)
  • Solitary fibrous tumor (SFT) is a clinically rare tumor derived from mesenchymal spindle cells. (bvsalud.org)
  • Due to the similar genetic characteristics it shares with hemangiopericytoma, in 2016, the World Health Organization (WHO) classified it as a single disease called solitary fibrous tumor (SFT)/hemangiopericytoma. (bvsalud.org)
  • The tumor was surgically removed and sent for pathologic examination, which confirmed that the tumor was consistent with a solitary fibrous tumor(WHO III). (bvsalud.org)
  • 1,2) Nuclear expression of STAT6 is found in nearly all cases of solitary fibrous tumor (SFT) and is very limited in other soft tissue neoplasms making it a highly sensitive and specific immunohistochemical marker for SFT and may help to distinguish this tumor type from histologic mimics. (biocare.net)
  • Meningeal solitary fibrous tumor/hemangiopericytoma: Emphasizing on STAT 6 immunohistochemistry. (biocare.net)
  • Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics. (biocare.net)
  • A tumor (abnormal growth of tissue) of the nervous system. (beds.ac.uk)
  • The first step in the management of orbital tumors is to differentiate the malignant tumors from the benign ones. (cybersight.org)
  • It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (lookformedical.com)
  • Metastases reach the central nervous system (CNS) via hematogenous spread of tumor cells. (medscape.com)
  • Although previous studies are retrospective and of limited number, involving small study groups and different types of patient management, several authors have reported a 30% incidence of leptomeningeal metastases in patients with metastatic breast cancer overexpressing HER2 who were treated with trastuzumab, while 70 to 80% of cases of the disease were controlled systemically. (hal.science)
  • CA 15-3 in cerebrospinal fluid (CSF) detection might be useful in helping to diagnose CNS metastases, particularly where cytology results are negative--which applies to 30% of cases--because tumor markers are more sensitive in detecting the tumor process. (hal.science)
  • Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. (lookformedical.com)
  • In the univariate analysis, primary tumor, age and the presence of metastases in the posterior fossa (PFBMs) were also significative. (preprints.org)
  • Symptoms depend on the location and occur as a result of the tumor pressing on nearby tissue. (wikipedia.org)
  • Tumor cells are released into the circulation, arrest in end arteries, penetrate the blood-brain barrier, enter the CNS, and establish growth in the new tissue. (medscape.com)
  • MRI spectroscopy can be used to detect malignant meningiomas by comparing the metabolic and chemical contents of the healthy tissue with malignant tumor. (medscape.com)
  • The tissue plane between tumor and brain was easily developed using standard microsurgical technique. (surgicalneurologyint.com)
  • Ability of neoplasms to infiltrate and actively destroy surrounding tissue. (lookformedical.com)
  • In this group they represent about 30% of brain tumors. (wikipedia.org)
  • Meningiomas are the most frequently diagnosed of all primary brain tumors, including glioblastomas, and of all other central nervous system tumors. (amjcaserep.com)
  • Meningiomas are also the most common extra-axial tumors in the brain and the most frequently occurring tumors of mesodermal or meningeal origin. (medscape.com)
  • Because the pia and arachnoid form a membranous barrier between brain and tumor, some meningiomas grow into the subarachnoid space, but invasion of the brain is infrequent. (medscape.com)
  • a mushroom-like appearance reflects tumor invagination in the brain parenchyma. (medscape.com)
  • Dr. David Raleigh is a radiation oncologist who specializes in brain tumors. (ucsf.edu)
  • Raleigh's research focuses on understanding the biological processes that cause brain tumors to grow. (ucsf.edu)
  • Subdural hemorrhage Subdural Hemorrhage Subdural hemorrhage (SDH) is bleeding into the space between the dural and arachnoid meningeal layers surrounding the brain. (lecturio.com)
  • Subdural Hemorrhage ) is bleeding into the space between the dural and arachnoid meningeal layers surrounding the brain Brain The part of central nervous system that is contained within the skull (cranium). (lecturio.com)
  • Chronic SDH SDH Subdural hemorrhage (SDH) is bleeding into the space between the dural and arachnoid meningeal layers surrounding the brain. (lecturio.com)
  • In a similar fashion to sonography, CT proved very versatile for the evaluation of congenital malformations of the brain, CNS infections, trauma, and primary brain tumors. (ajnr.org)
  • Clinical and demographic data, with special attention to sex, age, primary tumor, brain tumor-related epilepsy (BTRE), number and brain location of BMs, Karnofsky Performance Status (KPS), the updated DS-GPA prognostic index and the survival estimated according to the Kaplan-Meier model from the date of radiosurgery were analyzed. (preprints.org)
  • Hemorrhages within brain neoplasms seem to remain underreported, including angiomatous. (keaipublishing.com)
  • The overall effectiveness ranges from being curative for some cancers, such as some leukemias, to being ineffective, such as in some brain tumors, to being needless in others, like most non-melanoma skin cancers. (worldsbest.rehab)
  • However, 56.2% of reported metastatic meningiomas originated from benign (Grade I) and intermediary (Grade II) tumors, as in our case [2]. (amjcaserep.com)
  • Tumors affecting the orbit include benign and malignant neoplasms arising from the various structures in the orbit including the blood vessels, nerves, bones, orbital fat and other soft tissues. (cybersight.org)
  • Complete surgical excision remains the primary treatment of choice for well-defined, clinically benign orbital tumors. (cybersight.org)
  • Is it a benign tumor or a malignant tumor? (cybersight.org)
  • Before I go into it, orbital tumors are primarily classified as benign and malignant primary tumors or secondary tumors. (cybersight.org)
  • ABSTRACT: Hemangiopericytoma is a mesenchymal neoplasm that derives from pericytes surrounding the capillaries presenting overexpression of PSMA, which can be a source of pitfall in 68 Ga-PSMA-11 PET/CT. (bvsalud.org)
  • Sinonasal Hemangiopericytoma (HPC) is a rare vascular tumor originated from Zimmermann's pericyte with not well valuable course. (bvsalud.org)
  • In most cases of metastatic meningiomas, surgical resection of the original tumor was followed by progression within 5 years of diagnosis [4], leading to the hypothesis that surgical resection might initiate meta-static spread [2]. (amjcaserep.com)
  • The symptoms of nausea, vomiting and constipation could orientate the first diagnosis to an ileus associated with an abdominal recurrence of the tumor. (prodiagnosis.org)
  • It is usually normal to associate some symptoms, such as nausea and vomiting, with the digestive system, even more so when the diagnosis was of a digestive neoplasm. (prodiagnosis.org)
  • Meningeal carcinomatosis is a very well known diagnosis for a medical oncologist. (prodiagnosis.org)
  • Knowledge of these tumors is crucial for neurosurgeons to include them in preoperative differential diagnosis. (bvsalud.org)
  • This study describes the importance of investigating neuro-ophthalmic findings, which might provide clues for the localization of lesions, including tumors, to aid in diagnosis. (e-jvc.org)
  • The purpose of this case study is to describe the ophthalmic presentation and note the diagnosis of a cavernous sinus tumor in a dog with neuro-ophthalmologic deficits. (e-jvc.org)
  • On the other hand, for a suspected malignant tumor, an incision biopsy is the first step in the management to obtain a histopathologic diagnosis before a definitive therapy can be planned. (cybersight.org)
  • Comparative RNA-seq analysis aids in diagnosis of a rare pediatric tumor. (beds.ac.uk)
  • The incidence of melanoma is increasing faster than that of any other malignant neoplasm, except for lung cancer in women. (medscape.com)
  • Tumors or cancer of the LUNG. (lookformedical.com)
  • MRI showed a heterogeneous enhancing neoplasm of the anterior fossa. (archivosdeneurociencias.org)
  • Significant factors contributing to recurrence include atypical and malignant histologic types and heterogeneous tumor contrast enhancement on CT scans. (medscape.com)
  • Загальні відомості про лімфоми Lymphomas are a heterogeneous group of tumors arising in the reticuloendothelial and lymphatic systems. (msdmanuals.com)
  • Abdominal and pelvic ultrasound examinations were performed and revealed two huge, heterogeneous retroperitoneal masses located on the rectouterine fossa adjacent to the inferior vena cava, which measured between 126x103 and 95x78 mm in size (Fig. 1A and B). The tumors exhibited multiple scattered areas of increased echogenicity with dense posterior shadowing that suggested foci of calcification. (docksci.com)
  • The present invention relates to compositions and methods for treating cancerous tumors, including naïve, metastatic and recurrent cancers. (justia.com)
  • Maxillary sinus carcinoma is the most common type of paranasal sinus cancer ( 1 ), and squamous cell carcinoma is the primary histological type of maxillary sinus tumors. (brieflands.com)
  • These tumors differ in their histologic and, possibly, biologic characteristics. (medscape.com)
  • Neuroradiologists and neurosurgeons must be aware of both the typical and the atypical imaging appearances of meningiomas, as there is some correlation with different histologic types of tumor. (medscape.com)
  • Some tumors can disseminate to the CNS via cerebrospinal fluid. (prodiagnosis.org)
  • In this case the study of the cerebrospinal fluid showed the presence of tumor cells. (prodiagnosis.org)
  • however, involvement of MM in the cerebrospinal fluid and lepto meningeal infiltration is considered rare. (who.int)
  • [ 1 ] MRI more accurately evaluates en plaque and posterior fossa meningiomas, which may be missed on CT scanning. (medscape.com)
  • Then, papilledema , visual deficits, and symptoms suggestive of a central nervous system (CNS) infection of any etiology (bacterial, viral, fungal ) may be seen if the nerve is compromised in the subarachnoid space, as various tumors, sarcoidosis , pseudotumor cerebri and meningitis have been described as potential etiologies [1]. (symptoma.com)
  • If surgery is not possible or all the tumor cannot be removed, radiosurgery may be helpful. (wikipedia.org)
  • Several treatment approaches are available, including conservative management and interventional modalities such as microsurgery, radiosurgery, and embolization, or a combination thereof. (medscape.com)
  • in 25% of patients a neoplasm is detected after neurologic symptoms onset (most common being ovarian teratoma). (medlink.com)
  • Flat tumors, termed en plaque, infiltrate the dura and grow as a thin carpet or sheet of tumor along the convexity dura, falx, or tentorium. (medscape.com)
  • Larger tumors may cause symptoms, depending on the size and location. (wikipedia.org)
  • citation needed] Tumors of the Sylvian aqueduct may cause myriad motor, sensory, aphasic, and seizure symptoms, depending on the location. (wikipedia.org)
  • These symptoms also could be associated with the spreading of the tumor to the Central Nervous System (CNS). (prodiagnosis.org)
  • 04 ). Given the prodromal symptoms and meningeal involvement, patients are frequently diagnosed speculatively with "test negative" meningitis of infectious etiology. (medlink.com)
  • Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. (lookformedical.com)
  • [ 1 ] The primary tumor may occur at any location on the skin or, less commonly, on the mucus membranes or other locations. (medscape.com)
  • Secondary CNS melanoma most often results from hematogenous spread from a known or unknown primary tumor. (medscape.com)
  • Although hemorrhage prevention is the primary aim of AVM surgery, seizure control should also be at the forefront of therapeutic management. (medscape.com)
  • These are the primary tumors. (cybersight.org)
  • There's the list off primary tumors not in any particular order. (cybersight.org)
  • Other variables such as the type of primary tumor, age and PFBMs could also influence survival, although further studies are needed. (preprints.org)
  • The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. (lookformedical.com)
  • Cystic Lesion are not tumors but they come in the realm of oncologists because they referred get referred to in ocular oncologist or Oculoplastics specialists. (cybersight.org)
  • Ewing's sarcoma and peripheral primitive neuroectodermal tumor (ES/pPNET) belongs to a family of round-cell neuroectodermally derived tumors. (surgicalneurologyint.com)
  • Genotyping of 69 histiocytic lesions revealed that 23/48 Langerhans cell lesions were BRAF -V600E-mutant whereas all non-Langerhans cell lesions (including dendritic cell sarcoma, juvenile xanthogranuloma, Rosai-Dorfman disease, and granular cell tumor) were wild-type. (oncotarget.com)
  • The patient's magnetic resonance imaging showed a mass adhering extensively to the dura mater, with adjacent thickening of the meninges and evidence of a meningeal tail sign. (bvsalud.org)
  • Intraoperatively, the tumor was found to have breached the dura and as suggested by preoperative imaging, had invaded bone [ Figure 3 ]. (surgicalneurologyint.com)
  • a) Intraoperative photograph of the tumour breaching dura, (b) The tumour had extended through the skull. (surgicalneurologyint.com)
  • 1, 2016, entitled "A New Method for Promoting Tumor Necrosis" and provisional application Ser. (justia.com)
  • Grade III anaplastic tumors are distinguished by their agressiveness, with invasion into surrounding areas and lack of demarcation between the tumor and parenchyma. (medscape.com)
  • ES/pPNET is distinct from central primitive neuroectodermal tumors (cPNETs), which are central nervous system embryonal tumors most commonly arising in the supratentorial parenchyma. (surgicalneurologyint.com)
  • The study objectives are to assess the safety, tolerability and pharmacokinetics (PK) of CYT-0851 in patients with relapsed/refractory B-cell malignancies and advanced solid tumors and to identify a recommended Phase 2 dose as a monotherapy and in combination with chemotherapy for evaluation in these patients. (ucsf.edu)
  • Dosage of chemotherapy can be difficult: If the dose is too low, it will be ineffective against the tumor, whereas, at excessive doses, the toxicity (side-effects) will be intolerable to the person receiving it. (worldsbest.rehab)
  • Syphilitic infection of the nervous system results in the most chronic, insidious meningeal inflammatory process known. (medscape.com)
  • Optic nerve swelling or jumpy eye movements (nystagmus) may occur at any age and warrants immediate work-up for a central nervous system tumor. (symptoma.com)
  • The study group included 56.5 % of patients with hematological malignancies and 20.2 % with solid neoplasms [ 7 ]. (ijpsonline.com)
  • Hirose T, Tani T, Shimada T, Ishizawa K, Shimada S, Sano T. Immunohistochemical demonstration of EMA/Glut1-positive perineurial cells and CD34-positive fibroblastic cells in peripheral nerve sheath tumors. (archivosdeneurociencias.org)
  • The objective of this protocol was to develop a reference tool for the evaluation and management of febrile neutropenia in a fourth-level cancer hospital in Ecuador and provide a guideline for a timely and adequate care of cancer patients. (ijpsonline.com)
  • This classification allows patients to be categorized into risk groups for their management[ 3 ]. (ijpsonline.com)
  • Malignant plasma cells in meningeal MM out of 2000 patients with bone marrow produce an immunoglobulin, MM, was reported was by Schluterman et al. (who.int)
  • Diffusely invasive supratentorial rosette-forming glioneuronal tumor: illustrative case. (umassmed.edu)
  • The medical oncologist made a short differential between encephalitis , but no fever was measured, viral or bacterial meningitis , but there was no neck stiffness or meningeal carcinomatosis. (prodiagnosis.org)
  • The following text points out several possibilities and chemical pathways in which "Intume" chlorine dioxide intervention can destroy tumors and prevent proliferation of cancer cells. (justia.com)
  • For a growing number of tumors the BRAF V600E mutation carries therapeutic relevance. (oncotarget.com)
  • Neurocritical Care Management of the Neurosurgical Patient. (archivosdeneurociencias.org)
  • Although the tumor was considered to have been fully resected and had not spread to any nodes, the patient died of recurrent cancer within 1 year. (medscape.com)
  • The patient performed an extemporaneous biopsy with subsequent en-bloc removal in operating room, without prior embolization, with the Centripetal Endoscopic Sinus Surgery technique (CESS). (bvsalud.org)
  • The patient underwent tumor resection without adjuvant treatment. (bvsalud.org)
  • When you have a patient with orbital tumor, we have to ask these questions and answer ourselves. (cybersight.org)
  • Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. (lookformedical.com)
  • The chlorine dioxide compositions are injected directly into the cancerous tumor and the resulting tumor is effectively eliminated from the patient or subject over a period of one to several days to a few weeks, often after a single injection, or multiple injections at one session into the tumor. (justia.com)
  • Cancer cells are rich in polyamines which is necessary for survival and growth of tumors. (justia.com)
  • Because only a fraction of the cells in a tumor die with each treatment (fractional kill), repeated doses must be administered to continue to reduce the size of the tumor. (worldsbest.rehab)
  • The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause. (lookformedical.com)
  • Why are olfactory ensheathing cell tumors so rare? (archivosdeneurociencias.org)
  • While calcification is found in up to 25% of grade I tumors, it is a rare finding in grade II tumors. (medscape.com)
  • Cytological examination of fine-needle aspiration samples of the mass revealed a neuroendocrine tumor. (e-jvc.org)
  • Not to forget the rest of the ocular examination including visual acuity, color vision, assessment of the pupil for Relative Afferent Pupillary Defect, Schirmers specifically for Lacrimal Gland Tumors, basic ocular examination, specific cranial nerve examination and if you think that the tumor is a secondary one, rising from the nasal cavity or Paranasal Sinuses then we have to do oral and nasal examination as well. (cybersight.org)
  • Tumors or cancer of the PANCREAS. (lookformedical.com)
  • Tumors or cancer of the SKIN. (lookformedical.com)
  • Tumors or cancer of the LIVER. (lookformedical.com)
  • Tumors or cancer of the THYROID GLAND. (lookformedical.com)
  • Chlorine dioxide (ClO2), a strong oxidant, can safely be injected into a subject's body, including a tumor, although the compound has not yet been utilized as a cancer treatment in this manner. (justia.com)
  • STAT signaling is critical for cellular processes such as embryonic development, immune tolerance and tumor surveillance, and regulation of cell differentiation, growth, and apoptosis. (biocare.net)
  • Meningiomata also may occur as a spinal tumor, more often in women than in men. (wikipedia.org)