Membrane potential mechanism setting the membrane potential. Medical search. Frequent questions

The Drosophila follicle-cell epithelium provides an appropriate model system for studying the potential role of electrochemical signals, like intracellular pH (pH i ) and membrane potential (V mem ), during development. (biomedcentral.com)
The process restores the excess of intracellular potassium and extracellular sodium and reinstates the negative resting membrane potential. (medscape.com)
ROS may induce intracellular calcium increase and subsequent contraction of PASMCs via direct or indirect interactions with protein kinases, phospholipases, sarcoplasmic calcium channels, transient receptor potential channels, voltage-dependent potassium channels and L-type calcium channels, whose relevance may vary under different experimental conditions. (ersjournals.com)
The first intracellular, light-evoked responses recorded in the vertebrate retina were slow, negative going changes in membrane potential that lasted for as long as the light stimulus was present (Fig. 1). (org.es)
However, later intracellular marking techniques, in which dyes were injected from the electrode tips into the cytoplasm of the recorded neuron, revealed that horizontal cells, second order neurons postsynaptic to cones, were the source of the S-potentials (3, 4). (org.es)
Consequently, within this framework, the phase signal will be predominantly sensitive to any mechanism modifying the concentration of intracellular compounds, including transmembrane water movements, which accompany various ionic fluxes. (jneurosci.org)
These two 'clocks'undoubtedly interact, as trans-sarcolemmal currents involved in pacemaking include calcium-carrying mechanisms, while intracellular calcium cycling requires trans-sarcolemmal ion flux as the mechanism by which it affects membrane potential. (ox.ac.uk)
The large-conductance, Ca 2+ and voltage-activated K + channel (BK, also termed as BK Ca , Maxi-K, K Ca1.1 or Slo1) is a unique member of the mammalian K + channel family, which has the largest single channel conductance and is dually activated by membrane voltage and intracellular Ca 2+ . (mdanderson.org)
This work package utilises our large islet RNA data sets as well as a new human islet cell encyclopedia generated by single-cell RNA sequencing, and focuses on miRNA translation pathways, membrane receptor and intracellular Ca2+ signalling pathways. (lu.se)

Once membrane depolarization is complete, the membrane becomes impermeable to sodium ions again, and the conductance of potassium ions into the cell increases. (medscape.com)
Local anesthetics inhibit depolarization of the nerve membrane by interfering with both Na+ and K+ currents. (medscape.com)
This depolarization was thought of as excitation, and if the excitation was large enough, action potentials, or nerve spikes, were generated to transfer signals down the length of the nerve-cell axon. (org.es)
Sodium ions can continuously leak through this opening, causing sustained membrane depolarization, which paralyzes the muscle. (lbl.gov)
The positively charged ions entering the cell cause the depolarization characteristic of an action potential. (wikipedia.org)

This facilitates interaction of SET with the newly translated cytoplasmic domains of CD47 and results in subsequent translocation of CD47 to the plasma membrane via activated RAC1 (ref. 5). (nih.gov)
Potential mechanisms include DAGLA haploinsufficiency at the plasma membrane or dominant negative effect. (wustl.edu)
Ca(2+) signals not only depend on the net Ca(2+) influx through CRAC channels but also depend on other Ca(2+) influx mechanisms, K(+) channels or Cl(-) channels (which determine the membrane potential), Ca(2+) export mechanisms like plasma membrane Ca(2+) ATPase (PMCA), sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) or Na(+)-Ca(2+) exchangers, and (local) Ca(2+) buffering often by mitochondria. (unibe.ch)
The passive diffusion or active transport of water through the plasma membrane is associated with several cellular processes. (jneurosci.org)
HvPIP1;6, a Barley (Hordeum vulgare L.) Plasma Membrane Water Channel Particularly Expressed in Growing Compared with Non-Growing Leaf Tissues. (lu.se)

This resting potential is determined by the concentration gradients of 2 major ions, Na + and K + , and the relative membrane permeability to these ions (also known as leak currents). (medscape.com)
In addition, because the nerve membrane is permeable to potassium ions and impermeable to sodium ions, 95% of the ionic leak in excitable cells is caused by K + ions in the form of an outward flux, accounting for the negative resting potential. (medscape.com)
Initially, sodium ions gradually enter the cell through the nerve cell membrane. (medscape.com)
The entry of sodium ions causes the transmembrane electric potential to increase from the resting potential. (medscape.com)
Once the potential reaches a threshold level of approximately -55 mV, a rapid influx of sodium ions ensues. (medscape.com)
Our findings provide a theoretical basis for ions transport in sub-nanochannels and an alternative strategy for design ions separation membranes. (nature.com)
Moreover, the transport and separation mechanisms of ions within sub-nanochannels modulated by local charge density remains elusive and an effective strategy to fabricate high-efficiency mono-/divalent ions selective membranes is yet to be developed. (nature.com)
They span the membrane of cells, allowing the selective permeation of K + ions from one side of the membrane to the other, usually from the inside of the cell to the outside. (ersjournals.com)
Although the exact mechanism by which local anesthetics retard the influx of sodium ions into the cell is unknown, 2 theories have been proposed. (medscape.com)
In a resting state, muscle-cell membranes keep potassium ions and sodium ions separated, inside and outside the cell, respectively, creating a voltage across the membrane. (lbl.gov)
A chemical signal from a nerve cell sets off a cascade of events that results in sodium ions flowing into the cell, changing the membrane potential and and ultimately triggering muscle contraction. (lbl.gov)
The vote tally is by way of the membrane 'potential', a voltage that rises by way of forcing a gradient of ions to the two sides of the nerve membrane. (pediatric-orthopedics.com)
Other nerves release something that makes the cell pores turn into machines that actively pump ions to concentrate like charges to one side of the membrane (all the ++++ to one side and the --- to the other. (pediatric-orthopedics.com)
Ion channels are membrane protein complexes that translocate ions across cell or organelle membranes, underlying a broad range of the most basic physiological processes from nerve and muscle excitability, to membrane potential setting, pH/cell volume regulation, secretion and absorption. (mdanderson.org)

Here we show in human cell lines that alternative 3' UTRs differentially regulate the localization of membrane proteins. (nih.gov)
3' UTR-dependent protein localization has the potential to be a widespread trafficking mechanism for membrane proteins because HuR binds to thousands of mRNAs, and we show that the long 3' UTRs of CD44, ITGA1 and TNFRSF13C, which are bound by HuR, increase surface protein expression compared to their corresponding short 3' UTRs. (nih.gov)
The disease has been known to stem from mutations in certain membrane proteins that channel and regulate the flow of sodium into cells. (lbl.gov)
For example, some favorite modifications can lead to the protein being degraded which provides a mechanism to get rid of proteins which cause disease. (upenn.edu)

Mitochondrial protein degradation is not triggered by loss of mitochondrial membrane potential or oxidative stress. (elifesciences.org)
In our model of 3' UTR-dependent protein localization, the long 3' UTR of CD47 acts as a scaffold to recruit a protein complex containing the RNA-binding protein HuR (also known as ELAVL1) and SET to the site of translation. (nih.gov)
X-ray crystallography of a membrane protein provided a structural understanding of how a single mutation can result in periodic muscle paralysis. (lbl.gov)
Three states of the voltage-sensing domain (VSD) of a membrane-channel protein. (lbl.gov)
Affinity tags can reduce merohedral twinning of membrane protein crystals. (lu.se)
1] In a second example, I concentrate on the role of Influenza's matrix protein in virus budding and search for mechanisms by which the protein can induce membrane deformations. (lu.se)

Here, we studied molecular mechanisms underlying the phenomenon. (mdpi.com)
A more probable hypothesis for acupuncture's long term therapeutic effects is neuroplasity (changes that take place in the brain) although the specific understanding of the molecular mechanisms of neuroplasticity is still incomplete. (aahclinic.com)
2] In a last example, we use model membranes carrying glycosaminoglycans, to elucidate the molecular mechanisms modulating attachment and release of the herpes simplex virus. (lu.se)

Recent studies show that modulation of TASK-1 channels, either directly or indirectly by targeting their regulatory mechanisms, has the potential to control pulmonary arterial tone in humans. (ersjournals.com)
F. tularensis can infect humans through the skin, mucous membranes, gastrointestinal tract, and lungs. (cdc.gov)

Membranes with high ion permeability and selectivity are of considerable interest for sustainable water treatment, resource extraction and energy storage. (nature.com)
The LDH analyses confirmed a statistically significant increase in membrane permeability under dark conditions compared to the light conditions. (cetp-signal.com)
as well as the mechanism of percutaneous absorption that determines whether changes in skin permeability or vascular perfusion could further alter disposition. (cdc.gov)
Such interactions that occur in the dosing solution and with the stratum corneum membrane are termed solvatochromatic and are susceptible to developing quantitative structure permeability relationships (QSPRs) using linear free energy relationships (LFERs). (cdc.gov)

cause capacitive displacement currents that indirectly lead to slow membrane charge accumulation (on a time scale of tens of milliseconds), ultimately bringing the neurons to their AP discharge threshold. (eneuro.org)
At that time, neurons were thought only to be depolarized by synaptic inputs (inside becoming more positive relative to outside), thus having their inside-negative resting membrane potentials become reduced. (org.es)
In neurons, TASK channels carrying hyperpolarizing K + leak currents, and the pacemaker channel HCN2, carrying depolarizing I h , stabilize the membrane potential by a mutual functional interaction. (biomedcentral.com)
For thalamocortical relay neurons, it could be demonstrated that two ion channels, which are predominantly active at rest, strongly influence the resting membrane potential. (biomedcentral.com)

Ethylene dibromide is a liquid at ambient temperatures that can cause skin, eye, mucous membrane, and respiratory tract irritation. (cdc.gov)
Untreated, bacilli inoculated into skin or mucous membranes multiply, spread to regional lymph nodes and further multiply, and then may disseminate to organs throughout the body. (cdc.gov)

The intrinsic nature of the phenomenon was supported by the lack of rhythmic postsynaptic potentials as the cells were prevented from oscillating by outward current injection. (researchgate.net)

The mechanism is not yet completely understood, but studies have shown that volume regulated chloride channels and stretch sensitive non-selective cation channels lead to an increased probability in opening of L-type (voltage-dependent) Ca2+ channels, thus raising the cytosolic concentration of Ca2+ leading to a contraction of the myocyte, and this may involve other channels in the endothelia. (wikipedia.org)
V mem was most efficiently hyperpolarised by inhibiting voltage-dependent L-type Ca 2+ -channels or ATP-sensitive K + -channels, whereas the impact of the other ion-transport mechanisms was smaller. (biomedcentral.com)
One is a graph with the membrane voltage recorded in the soma (units: ms and mV), the two other panels have a representation of the cell's morphology. (yale.edu)
The sections in the first morphology change color dependending on their membrane voltage during the simulation. (yale.edu)

Alterations in the nerve cell membrane potential are termed the action potential. (medscape.com)

Leak currents are present through all the phases of the action potential, including setting of the resting membrane potential and repolarization. (medscape.com)
Of course, the same has also been shown for sub-sets of 'membrane-clock' ion currents, illustrating the redundancy of mechanisms involved in maintaining such basic functionality as the heartbeat, a theme that is common for vital physiological systems. (ox.ac.uk)

In addition we have recently started to explore the structure and molecular function of pain receptors from animals, i.e. transient receptor potential (TRP) ion channels, and their activation by temperature and various ligands. (lu.se)

Here, NICE theory is shown to provide a detailed predictive explanation for the ability of ultrasonic (US) pulses to also suppress neural circuits through cell-type-selective mechanisms: according to the predicted mechanism T-type calcium channels boost charge accumulation between short US pulses selectively in low threshold spiking interneurons, promoting net cortical network inhibition. (eneuro.org)
These results further support a unifying hypothesis for ultrasonic neuromodulation, highlighting the potential of advanced waveform design for obtaining cell-type-selective network control. (eneuro.org)

However, using a genetically encoded indicator, we found that calcium accumulates in the terminals of the interneurons along a time course consistent with the behavior and propose that this accumulation provides a mechanism for temporal integration of sensory feedback consistent with PI control. (caltech.edu)
Neither the 'membrane-' nor the 'calcium-clock' do, as such, inherently account for this rapid adaptation to circulatory demand (cellular Ca²⁺ balance changes over multiple beats, while variation of sarcolemmal ion channel presence takes even longer). (ox.ac.uk)
In this review, we discuss possible roles of mechano-sensitive mechanisms for the entrainment of membrane current dynamics and calcium-handling. (ox.ac.uk)

Conclusion A population pharmacokinetic model of sublingually administered tacrolimus in paediatric patients was developed to characterize different absorption mechanisms. (unav.edu)
Although the mechanism of absorption of a single chemical has been well studied, effects of co-administered chemicals on absorption of a systemic toxicant may ultimately determine whether this potential toxicity is ever realized. (cdc.gov)

Lacking a stimulation artifact and having a higher degree of spatial specificity, infrared neural stimulation (INS) has the potential to improve upon clinical ES for IONM. (nature.com)
Recently, intramembrane cavitation within the bilayer membrane was proposed to underlie both the biomechanics and the biophysics of acoustic bio-effects, potentially explaining cortical stimulation results through a neuronal intramembrane cavitation excitation (NICE) model. (eneuro.org)
2018) and sets up extracellular stimulation with either a point-current source, to simulate intracortical microstimulation (ICMS), or a uniform E-field distribution, with a monophasic, rectangular pulse waveform in both cases. (yale.edu)

3. About 80% of the neurones with intact cortical connections were set into the slow oscillatory mode by bringing their membrane potential to between -68 and -90 mV. (researchgate.net)
6. Barbiturate administration suppressed the slow oscillatory mode, an effect accompanied by a decrease in the membrane input resistance. (researchgate.net)
As the combined contributions of the various underlying oscillatory mechanisms are integrated at the pacemaker cell level into a single output--a train of pacemaker action potentials--we will not adhere to a metaphor that implies separate time-keeping units ('clocks'), and rather focus on cardiac pacemaking as the result of interactions of a set of coupled oscillators, whose individual contributions vary depending on the pathophysiological context. (ox.ac.uk)

They regulate the excitability of cells and contribute to their resting membrane potential [ 1 , 2 ]. (ersjournals.com)
That is what this thing does, it passes chloride and in doing so quiets the nerve membrane excitability. (pediatric-orthopedics.com)

The material from each step isscreened using acellular and in vitro assays for evaluating general toxicity, mechanisms of toxicity, and macrophage function. (cdc.gov)
The cytotoxicity and mechanism of screening clustered with the purity grade of BNNTs, illustrating that greater purity of BNNT corresponds to greater toxicity. (cdc.gov)

Mechano-sensitivity of cardiac pacemaker function: pathophysiological relevance, experimental implications, and conceptual integration with other mechanisms of rhythmicity. (ox.ac.uk)
Embryologic evidence of generation of the cardiac conduction system illuminates the respective roles of this specialized set of cells. (wikipedia.org)

Nonetheless, the 'clock' metaphor has been conceptually stimulating, in particular since there is evidence to support the view that either 'clock'could be sufficient in principle to set the rate of pacemaker activation. (ox.ac.uk)
Following the conceptual path of identifying individual groups of sub-mechanisms, it is important to remember that the heart is able to adapt pacemaker rate to changes in haemodynamic load, even after isolation or transplantation, and on a beat-by-beat basis. (ox.ac.uk)
the specific differences in ion channels and mechanisms of polarization give rise to unique properties of SA node cells, most importantly the spontaneous depolarizations necessary for the SA node's pacemaker activity. (wikipedia.org)

First, ES requires contact with tissue to excite action potentials. (nature.com)
The oscillation did not depend upon the occurrence of fast action potentials and did not outlast the imposed hyperpolarization. (researchgate.net)
The action potential is not propagated because the threshold level is never attained. (medscape.com)
S-potentials, however, were not depolarized by light, but rather hyperpolarized, and did not fire action potentials, even with the brightest light stimuli. (org.es)
The mechanism of action of daptomycin is distinct from that of any other antibiotic. (globalrph.com)
This automatic initiation of action potentials requires spontaneous diastolic depolarisation, whose rate determines normal rhythm generation in the heart. (ox.ac.uk)

Other research has focused on the peripheral and central neural mechanisms, including spinal gating and descending inhibitory pathways, that might explain the clinical observations of short-term pain relief. (aahclinic.com)
The involvement of the spinal gating and descending inhibitory pathways mechanisms in acupuncture is supported by animal experiments. (aahclinic.com)
Identify targetable mechanisms and pathways underlying initiation and progression of SIDD. (lu.se)

Wild-type cells were treated with concanamycin A for 4 hr, stained with mitochondrial membrane potential fluorescent dyes DiOC 6 ( A ) or TMRM ( B ), and analyzed by flow cytometry. (elifesciences.org)

Typically, signals for gradient pumping, making high potential which may fire the nerve use an amine transmitter norepinephrine also known as noradrenaline. (pediatric-orthopedics.com)

Soothing, requires lowering that potential and - just say no - chemistry which is generally allowing chloride to pass through chloride specific pores in the membrane, lowering the electrical gradient across the membrane. (pediatric-orthopedics.com)

Our data show that in the Drosophila follicle-cell epithelium stage-specific pH i - and V mem -gradients develop which result from the activity of several ion-transport mechanisms. (biomedcentral.com)
To investigate the cellular basis of this effect, we performed whole-cell patch-clamp recordings from the set of identified visual interneurons [horizontal system (HS) cells] thought to control this reflex during tethered flight. (caltech.edu)
Conversely, these mechanisms demand high energy consumption, promoting important metabolic changes in the cell. (frontiersin.org)
At first, the cell type of origin for S-potentials was not really known other than that microelectrode tips were somewhere in the outer retina. (org.es)
Run mknrndll and point it to the 'mechanisms' directory inside the unzipped cell package directory 4. (yale.edu)
Initially there are no stimuli present, which means that the cell will stay at its resting membrane potential. (yale.edu)
Thereby, the acidified milieu after arterial occlusion most probably influences the activity of acid-sensing ion channels as well as the cell membrane potential. (biomedcentral.com)
It penetrates and lives in the cell membrane as a pore - a grommet. (pediatric-orthopedics.com)
Ion channels have long been key therapeutic targets in disease intervention and pharmaceutical drug development because of their direct involvement in diverse diseases, vulnerability to small molecular modulation, and accessibility for direct activity measurement on cell membranes by patch-clamp recording from whole cell to single molecule levels. (mdanderson.org)
Like a neuron, a given myocardial cell has a negative membrane potential when at rest. (wikipedia.org)
Virus entry is a complex dynamic multistep process requiring a series of fine-tuned events mediating virus diffusion through the glycocalyx, its attachment to the cell membrane and lateral diffusion to the point of entry. (lu.se)
The aim of our research is elucidate the mechanisms by which viral pathogens interact with the cell'membrane to crosses it and penetrate into the cell. (lu.se)
Our research strategy widely relies of the use of artificial lipid bilayers to mimic in vitro the basic molecular architecture of the cell membrane. (lu.se)

While the inhibition of Na + /H + -exchangers (NHE) and amiloride-sensitive Na + -channels or of V-ATPases resulted in relative acidification, inhibiting the other ion-transport mechanisms led to relative alkalisation. (biomedcentral.com)
A ) Schematic illustration showing that loss of vacuolar acidity (2) through aging or concanamycin A (conc A)-mediated inhibition of the Vacuolar H + -ATPase (1) leads to loss of mitochondrial function (3) through an unknown mechanism. (elifesciences.org)
This group of flavonoids, flavonol, could be investigated further to discover the common mechanisms of inhibition of dengue virus replication. (who.int)

As a result, ES excites distant neural tissue beyond the intended target leading to potential misdiagnosis of nerve functionality and viability. (nature.com)

Several transcriptional and post-transcriptional regulatory mechanisms control the preferential use of glucose over other sugars. (encyclopedia.pub)

4. Anatomical or functional disconnection from related cortical areas resulted in a membrane potential hyperpolarization of about 9 mV and in the occurrence of spontaneous slow oscillations in virtually all recorded neurones. (researchgate.net)

A lack of oxygen and glucose are considered to be key mediators of ischemic neurodegeneration while the exact mechanisms are yet unclear. (biomedcentral.com)

We also discuss the more elusive potential mechanisms that link wounding to tissue growth and patterning. (frontiersin.org)
The depletion of oxygen or glucose in ischemic brain tissue sets off a series of interrelated events that result in neurodegeneration. (biomedcentral.com)
Also, they can clump together or agglomerate, which can affect their potential for settling in the lungs if inhaled, their ability to penetrate the body's membranes and consequently move from the lungs to other organs, and their interaction with cells and tissue. (cdc.gov)

AAH is not only a center for assessment and treatment but is also a basic and clinical research facility in which we investigate and advance mechanisms and treatments for functional, integrated, multi-dimensional pain relief. (aahclinic.com)

Diverse translational and research applications could benefit from the noninvasive ability to reversibly modulate (excite or suppress) CNS activity using ultrasound pulses, however, without clarifying the underlying mechanism, advanced design-based ultrasonic neuromodulation remains elusive. (eneuro.org)

citation needed] Many cells have resting membrane potentials that are unstable. (wikipedia.org)
During recovery, counterregulatory mechanisms take place, and the activated cells return to the homeostatic state. (frontiersin.org)
This gene subfamily is constitutively active at physiological resting membrane potentials in excitable cells, including smooth muscle cells, and has been particularly linked to the human pulmonary circulation. (ersjournals.com)
2. A slow (0.5-4 Hz) membrane potential oscillation was observed in thalamocortical cells recorded in motor, sensory, associational and intralaminar thalamic nuclei. (researchgate.net)
2.4 S-Potentials and Horizontal cells. (org.es)
Since being first described in fish retinas, S-potentials have been recorded from retinal horizontal cells in all vertebrate classes. (org.es)

This sequence pattern is conserved among diverse plant peptides, suggesting that plant peptide hormone receptors may share a common ligand binding mode and activation mechanism. (elifesciences.org)
To illustrate the potential of such a biophysical approach, I will, in my presentation, first focus on the interaction between norovirus and glycolipid-containing membranes and investigate the role of ligands mobility and ligand clustering in modulating the affinity of the virus particle to the membrane. (lu.se)

These findings underscore the clinical potential of INS to improve IONM and surgical outcomes. (nature.com)
Our hope is that through our work, we will not only provide insight into the processes underlying disease, but also provide new therapeutic strategies which can be used in a clinical setting to ultimately improve patient outcomes. (upenn.edu)

The myogenic mechanism showed 'descending' resistance changes, starting in the larger arteries, and successively affecting downstream preglomerular vessels at increasing arterial pressures. (wikipedia.org)
8. These results demonstrate that the majority of thalamocortical neurones are endowed with electrophysiological properties allowing them to oscillate at 0.5-4 Hz, if they have a membrane potential more negative than -65 mV and a high input resistance. (researchgate.net)

Hypoxic pulmonary vasoconstriction (HPV), also known as the von Euler-Liljestrand mechanism, is an essential response of the pulmonary vasculature to acute and sustained alveolar hypoxia. (ersjournals.com)
Hypoxic pulmonary vasoconstriction (HPV), also known as the von Euler-Liljestrand mechanism, is an intrinsic mechanism of the pulmonary vasculature in response to alveolar hypoxia, to match ventilation to perfusion and optimise pulmonary gas exchange ( figure 1 ). (ersjournals.com)

Combined with in-vitro proliferation assays using CRISPR-Cas9/RNAi and patient survival analysis, MEK inhibitors PD19830 and BRD-K12244279, pilocarpine, and tremorine were discovered as potential new drug options for treating breast cancer. (cdc.gov)

Daptomycin for injection is not recommended in pediatric patients younger than one year of age due to the risk of potential effects on muscular, neuromuscular, and/or nervous systems (either peripheral and/or central) observed in neonatal dogs. (nih.gov)
The bladder and urethra are innervated by 3 sets of peripheral nerves arising from the autonomic nervous system (ANS) and somatic nervous system. (medscape.com)

Inspired by KcsA K + channel with size of ~5.6 Å and homogenous distribution of carbonyl oxygens, herein, MXene nanosheets and EDTA molecules are used as building blocks to construct artificial ion channel membranes with the right channel size, similar binding sites, and tunable charge density (Fig. 1a ). (nature.com)

E. coli nonspecifically transports glucose from the extracellular medium into the periplasmic space through the outer membrane porins. (encyclopedia.pub)
Ethanol (shown floating in the extracellular space) does something similar but attaches to another spot on that set of 7 pipe curls. (pediatric-orthopedics.com)

Myogenic mechanisms in the kidney are part of the autoregulation mechanism which maintains a constant renal blood flow at varying arterial pressure. (wikipedia.org)

In this protocol, we summarize a set of experiments that allow (quantitative) statements about CRAC channel activity using Ca(2+) imaging experiments, including the ability to rule out Ca(2+) signals from other sources. (unibe.ch)
While advantageous under normal circumstances, this property can be detrimental, as it has potential to allow the propagation of incorrect electrical signals. (wikipedia.org)

The membranes show the capability to recognize monovalent/divalent cations, achieving excellent K + /Mg 2+ selectivity of 121.2 using mixed salt solution as the feed, which outperforms other reported membranes under similar testing conditions and transcends the current upper limit. (nature.com)
Additionally, numerous transporters with overlapping sugar specificities for monosaccharides increase the potential capability to transport glucose [ 6 ] , indicating the extraordinary capability and plasticity of transporting and growing glucose as a carbon source. (encyclopedia.pub)

Anatomy52

Organisms18

Chemicals and Drugs98

Analytical, Diagnostic and Therapeutic Techniques and Equipment24

Phenomena and Processes56

Disciplines and Occupations4

Technology, Industry, Agriculture5

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Depolarization5

Plasma membrane5

Ions14

Proteins4

Protein6

Molecular mechanisms3

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Neurons4

Mucous2

Rhythmic1

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Nerve cell1

Currents2

Transient1

Selective2

Calcium3

Absorption2

Stimulation3

Oscillatory3

Excitability2

Toxicity2

Cardiac2

Pacemaker3

Action6

Pathways3

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Amine1

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Cell13

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