Loading...
  • expression
  • These findings demonstrate that MEF2D, a broadly expressed TF, contributes to retina-specific gene expression in photoreceptor development by binding to and activating tissue-specific enhancers cooperatively with CRX, a tissue-specific co-factor. (harvard.edu)
  • The unusual pattern of expression in brain suggests that this transcription factor may be important in the development of cortical architecture. (pnas.org)
  • Ectopic expression of the neuropeptide pigment-dispersing factor alters behavioral rhythms in Drosophila melanogaster. (semanticscholar.org)
  • Aberrance of adaptive responses such as long-term memory or late-phase synaptic plasticity has indeed been the hallmark of several genetically engineered mouse mutants in which the expression or the function of key transcription factors have been altered ( 2 , 3 ). (pnas.org)
  • 2. The method of claim 1 , wherein the expression levels of the at least ten genes indicative of recurrence of HCC are determined by at least one assay selected from the group consisting of: DNA microarray, oligonucleotide microarray, northern blotting, in situ hybridization, RNase protection assay, and reverse transcription polymerase-chain reaction assay. (google.com)
  • Alteration of MEF2 expression in two mutants affecting somitogenesis provides insight into the control of muscle formation in the embryo. (zfin.org)
  • regulates
  • SUMO modification or sumoylation is an essential post-translational modification that regulates protein functions including transcription, signal transduction, and DNA repair ( Geiss-Friedlander and Melchior, 2007 ). (frontiersin.org)
  • tumor
  • gene regulatory network that controls the activity of a positive feedback circuit on BMP signaling, involving the tumor necrosis factor alpha homolog eiger . (sdbonline.org)
  • myocyte
  • Here, we generated stably transformed murine ES (embryonic stem) cells that express a constitutively active form of myocyte enhancer factor 2C (MEF2CA). (jneurosci.org)
  • cortical
  • A local reduction in cortical GABAergic synapses after a loss of endogenous brain-derived neurotrophic factor, as revealed by single-cell gene knock-out method. (semanticscholar.org)
  • brain
  • b, qPCR of atrial natriuretic factor (ANF), brain natriuretic peptide(BNP) and Tenascin (TnC) on RNA extracted from the border zone of hearts 4 weeks after MI and injection of dsRed or GMT. (nih.gov)