BlockersARBsRenin-angiotAntihypertensive medicationsHypertensionACEIDiureticDiureticsReceptor antagonistsCardiacCalciumStatinsProton pump inhiDiabetesNephropathySymptomsComorbiditiesUnable to tolerateSGLT2TolerateChronic diseaseRegimensTreatmentEjection fractionCardiovascularComplicationsRenalKidneyNephrotic syndromeRiskLisinoprilIncludeCharacteristicsFindingsInterventionsProgressionOutcomes in PatientsDrugsAcute decompensated heart failureCoronaryStableLimb-threatenPrognosisMethodsAppropriate medicationMortalityResearchersAdult patientsClinically2023AdverseHeart failureConsecutivePulmonaryBlood pressure medicationsSurvivalCoughHealthcare
Blockers22
- For management of heart failure with reduced ejection fraction (HFrEF), medication classes consist of diuretics, angiotensin-receptor blockers (ARBs), angiotensin-converting enzyme (ACE) inhibitors, and beta-blockers. (medscape.com)
- Beta-blockers inhibit sympathetic activity and have been shown to reduce mortality in patients with heart failure with reduced ejection fraction. (medscape.com)
- The medications studied included angiotensin converting enzyme inhibitors, aldosterone antagonists, and beta blockers. (medindia.net)
- first-line antihypertensive medications include angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, dihydropyridine calcium-channel blockers and thiazide diuretics. (nature.com)
- β-blockers and calcium antagonists were correlated with increased risk, while angiotensin-converting enzyme inhibitors and angiotensin receptor blockers were actually associated with decreased risk. (madinamerica.com)
- While this may appear to be a low percentage, the relative increase in risk was striking: those taking β-blockers and calcium antagonists were twice as likely to develop a mood disorder as those taking angiotensin medications. (madinamerica.com)
- The results of the current study-a 100% increase in the likelihood of mood disorders for those taking β-blockers-mirror the concerns of previous researchers that these medications may lead to serious mental health consequences. (madinamerica.com)
- Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are associated with the least likelihood of developing depressive symptoms. (madinamerica.com)
- If β-blockers and calcium antagonists are found to be the appropriate medication for treating cardiac health, care must be taken to assess for the development of mood symptoms as side effects throughout the course of treatment. (madinamerica.com)
- The most commonly used medications are Angiotensin-Converting Enzyme (ACE) inhibitors, Angiotensin II Receptor Blockers (ARBs) and calcium channel blockers. (cedars-sinai.org)
- Comparative studies show ACE inhibitors are more effective than other antihypertensives (ie, beta blockers, calcium channel blockers) in reducing blood pressure and proteinuria, protecting renal function, and delaying onset of ESRD. (medscape.com)
- Specific medications should be based on individual patient characteristics, and may include angiotensin-converting enzyme inhibitors and/or beta blockers, with other drugs such as thiazide diuretics or calcium channel blockers, if needed. (aafp.org)
- To assess the effects of nurse-led titration (NLT) of beta-adrenergic blocking agents, angiotensin converting enzyme inhibitors (ACEIs), and angiotensin receptor blockers (ARBs) in patients with heart failure in terms of safety and patient outcomes. (cochrane.org)
- Beta-adrenergic blocking agents, angiotensin converting enzyme inhibitors (ACEIs), and angiotensin receptor blockers (ARBs) can improve survival and reduce hospital readmissions and are recommended as first-line therapy in the treatment of heart failure. (cochrane.org)
- In patients on antihypertensive medications (AHMs) such as angiotensin-converting-enzyme inhibitors (ACE-Is) or angiotensin receptor blockers (ARBs) undergoing inpatient non-cardiac surgery, what blood pressure (BP) management strategy reduces the risk of major vascular complications? (the-hospitalist.org)
- The mean age was 70 years, patients took a mean of two AHMs with a majority taking ACE-I or ARBS and/or beta-blockers. (the-hospitalist.org)
- At the dawn of evidence-based medicine, first-line treatment included any of the five medications: diuretics, beta-blockers, calcium channel blockers (CCBs), angiotensin-converting enzyme (ACE) inhibitors, or angiotensin receptor blockers (ARBs). (escardio.org)
- With the capability of inducing elevated expression of ACE2, the cellular receptor for SARS-CoV-2, angiotensin II receptor blockers or angiotensin-converting enzyme inhibitors (ARBs/ACEIs) treatment may have a controversial role in both facilitating virus infection and reducing pathogenic inflammation. (medrxiv.org)
- A combination of medications may also be trialed to help maximally dilate the micro vessels including beta blockers and calcium channel blockers. (tgh.org)
- The panel also recommended a "toolbox" of four different blood pressure medications that doctors could use treat patients -- diuretics, calcium channel blockers, angiotensin-converting enzyme (ACE) inhibitors, or angiotensin receptor blockers (ARBs). (healthinternetwork.org)
- These two classes of drugs are ARBs, angtiotensin receptor blockers, and ACEs, angiotensin converting enzyme inhibitors. (rothausmd.com)
- Background Concerns have been raised that angiotensin-converting enzyme-inhibitors (ACE-I) and angiotensin receptor blockers (ARBs) might facilitate transmission of severe acute respiratory syndrome coronavirus 2 leading to more severe coronavirus disease (COVID-19) disease and an increased risk of mortality. (nihr.ac.uk)
ARBs11
- We conducted a review of seven randomised controlled trials (1684 participants) comparing nurse titration of beta-adrenergic blocking agents, ACEIs, and ARBs with titration of these medications by a primary care physician. (cochrane.org)
- Despite evidence of a dose-dependent relationship of beta-adrenergic blocking agents, ACEIs, and ARBs with improving outcomes in patients with HFrEF, the translation of this evidence into clinical practice is poor. (cochrane.org)
- To assess the effects of NLT of beta-adrenergic blocking agents, ACEIs, and ARBs in patients with heart failure with reduced ejection fraction (HFrEF) in terms of safety and patient outcomes. (cochrane.org)
- 126 COVID-19 patients with preexisting hypertension at Hubei Provincial Hospital of Traditional Chinese Medicine (HPHTCM) in Wuhan from January 5 to February 22, 2020 were retrospectively allocated to ARBs/ACEIs group (n=43) and non-ARBs/ACEIs group (n=83) according to their antihypertensive medication. (medrxiv.org)
- The frequency of ARBs/ACEIs usage in hypertension patients with or without COVID-19 were comparable. (medrxiv.org)
- Among COVID-19 patients with hypertension, those received either ARBs/ACEIs or non-ARBs/ACEIs had comparable blood pressure. (medrxiv.org)
- Our findings thus support the use of ARBs/ACEIs in COVID-19 patients with preexisting hypertension. (medrxiv.org)
- Substituting the least expensive agent could have saved $1.16 million (47%) for PPIs, $162 thousand (17%) for ACE inhibitors and $14 thousand (4%) for ARBs over the year following discharge. (ices.on.ca)
- Similar to ACE inhibitors, ARBs contribute to lowering blood pressure by obstructing the action of angiotensin II. (novacorp.biz)
- Unlike ACE inhibitors, ARBs do not typically lead to persistent coughing. (novacorp.biz)
- We constructed mixed-effects logistic regression models to quantify the association between ACE-I/ARBs and all-cause mortality among people with COVID-19, adjusted for sociodemographic factors, comorbidities, concurrent medication, smoking status, practice clustering, and household number. (nihr.ac.uk)
Renin-angiot1
- Figure 3: Role of the renin-angiotensin-aldosterone system in the regulation of blood pressure. (nature.com)
Antihypertensive medications5
- Although usual perioperative care is commonly consistent with a hypertension-avoidance strategy (i.e., most patients continue their antihypertensive medications throughout the perioperative period and intraoperative mean arterial pressures of 60 mmHg are commonly accepted), a hypotension-avoidance strategy may improve perioperative outcomes. (biomedcentral.com)
- Patients on ≥ 1 chronic antihypertensive medication are also randomized to either of the two blood pressure management strategies, which differ in the management of patient antihypertensive medications on the morning of surgery and on the first 2 days after surgery, and in the target mean arterial pressure during surgery. (biomedcentral.com)
- The researchers found that the different classes of antihypertensive medications were associated with varying risk of developing depression and bipolar disorder. (madinamerica.com)
- Antihypertensive medications are commonly prescribed to treat high blood pressure. (madinamerica.com)
- Particularly given the ubiquity of prescriptions for antihypertensive medications, this study suggests that doctors should carefully consider which particular class of antihypertensive is indicated for each patient. (madinamerica.com)
Hypertension29
- The goal of medication treatment of group 2 pulmonary hypertension is to lower filling pressures and provide afterload reduction in patients with heart failure. (medscape.com)
- In settings of combined postcapillary and precapillary pulmonary hypertension, pulmonary vasodilators have not consistently been shown to improve symptoms or hemodynamics and some harm has been demonstrated in trials of these medications. (medscape.com)
- Phosphodiesterase-5 (PDE-5) inhibitors cause smooth muscle relaxation and antiproliferative effects in the vasculature, leading to a reduction in pulmonary artery pressure in patients with WHO group 1 pulmonary hypertension. (medscape.com)
- [ 16 ] Additionally, a smaller study looking at 34 patients with symptomatic heart failure and pulmonary hypertension showed improvement in exercise capacity, quality of life, and fewer hospitalizations for heart failure exacerbations in the sildenafil group compared with placebo. (medscape.com)
- The evaluation of patients with hypertension includes accurate standardized blood pressure (BP) measurement, assessment of the patients' predicted risk of atherosclerotic CVD and evidence of target-organ damage, and detection of secondary causes of hypertension and presence of comorbidities (such as CVD and kidney disease). (nature.com)
- Nonadherence to taking prescribed antihypertensive medication (antihypertensive) regimens has been identified as a leading cause of poor blood pressure control among persons with hypertension and an important risk factor for adverse cardiovascular disease outcomes. (cdc.gov)
- Relative risk reduction from blood pressure reduction is similar across populations with varying absolute risk, so the absolute benefit is greater in patients who are at higher risk independent of their hypertension (for example, patients with diabetes or hyperlipidemia), and such patients would be expected to benefit from more aggressive treatment to a lower blood pressure goal. (globalrph.com)
- A new study , published this month in the journal Hypertension , analyzed hospital records from 144,066 patients in the UK over a 5-year follow-up period. (madinamerica.com)
- He had no history of CAD, and the only medication he was taking was an angiotensin-converting enzyme inhibitor for hypertension. (hcplive.com)
- Patients with white-coat hypertension experience a spike in their blood pressure specifically when it is measured at the doctor's office but not in other settings, such as the home. (cedars-sinai.org)
- Patients with masked hypertension, on the other hand, have normal blood pressure readings at the doctor's office but the experience increases in blood pressure at other times of day or in different settings. (cedars-sinai.org)
- African-American men and patients with certain chronic conditions such as diabetes and kidney disease are also at increased risk of developing hypertension and masked hypertension. (cedars-sinai.org)
- Patients experiencing anxiety or stress over their doctor's appointment may be at increased risk of developing white-coat hypertension. (cedars-sinai.org)
- Patients with white-coat or masked hypertension often require special monitoring and testing to ensure they receive the most accurate diagnosis. (cedars-sinai.org)
- Lifestyle changes and medication often are used in combination to treat a patient's hypertension. (cedars-sinai.org)
- Some patients may have resistant hypertension, in which blood pressure may remain elevated despite the use of three or more different medications. (cedars-sinai.org)
- Patients with accurately diagnosed white-coat hypertension who do not have consistently high blood pressure at any other time may not need treatment with medications. (cedars-sinai.org)
- However, patients with this condition should be monitored by their physician, as they may be at an increased risk of developing hypertension in the future. (cedars-sinai.org)
- Initial assessment in a patient who is hypertensive should evaluate for cardiovascular risk and any hypertension-mediated organ damage. (aafp.org)
- Consider lifestyle interventions for three to six months before medication in patients with grade 1 hypertension and no comorbidities. (aafp.org)
- Although the prevalence of hypertension is increasing, many patients are underdiagnosed and undertreated. (aafp.org)
- Patients who have hypertension should receive counseling on the need for lifestyle modification. (aafp.org)
- Was there any difference in the severity of systemic hypertension between hypertensive RVO patients and the uncomplicated hypertensive control subjects? (bmj.com)
- Compared with the non-diabetic group, the diabetic group of patients comprised more women and had more comorbidities such as hypertension, dyslipidemia, renal impairment, peripheral vascular disease and prior ischemic heart disease. (springer.com)
- Vasotec (enalapril maleate) is an ACE ( angiotensin converting enzyme ) inhibitor used to treat high blood pressure ( hypertension ), congestive heart failure , kidney problems caused by diabetes , and to improve survival after a heart attack . (rxlist.com)
- 125 age- and sex-matched COVID-19 patients without hypertension were randomly selected as non-hypertension controls. (medrxiv.org)
- In addition, the medication history of 1942 hypertension patients that were admitted to HPHTCM from November 1 to December 31, 2019 before COVID-19 outbreak were also reviewed for external comparison. (medrxiv.org)
- Hypertension, thyroid disorders and diabetes were present in 32%, 28% and 17% of patients, respectively. (jcda.ca)
- Patients typically present with edema and nephrotic-range proteinuria and occasionally with microscopic hematuria and hypertension. (msdmanuals.com)
ACEI2
- There were 30, 8 and 11 colorectal cancer patients who took ACEI or ARB or beta-blocker, CCB and other antihypertensive drugs, respectively. (aging-us.com)
- Most patients with CMD have some degree of dysfunction of the vascular lining of the small vessels of the heart and benefit from medications including statins and angiotensin converting enzyme inhibitor (ACEi) or angiotensin II receptor blocker (ARB). (tgh.org)
Diuretic6
- With the heart's diminishing function, fluid can build-up in the lungs so most patients also take a diuretic. (medindia.net)
- Researchers found that treatment with one or a combination of these medications was associated with lower costs and higher quality of life when compared to just receiving a diuretic alone. (medindia.net)
- ZESTORETIC® (Lisinopril and Hydrochlorothiazide) combines an angiotensin converting enzyme inhibitor, lisinopril, and a diuretic, hydrochlorothiazide. (globalrph.com)
- The slight distinction is from JNC7, where the patients preferred the diuretic as their first choice. (healthinternetwork.org)
- omission of two interventions: routine patient education about a rescue dose of diuretic and lack of focused clinician education on pseudo-worsening kidney failure. (providence.org)
- We believe that a plan that includes a rescue-dose diuretic, whether administered by a patient, caregiver, or care facility, should be standard of care and measured for all discharges. (providence.org)
Diuretics2
- The team used an advanced statistical model to assess the specific incremental and cumulative health and cost benefit contributions of three medications compared with diuretics alone in the treatment of heart failure patients. (medindia.net)
- Being prescribed no antihypertensive medication or taking thiazide diuretics was associated with medium risk. (madinamerica.com)
Receptor antagonists1
- over half were antineoplastic agents (n = 24), angiotensin converting enzyme inhibitors (n = 10), angiotensin II receptor antagonists (n = 8), and anticonvulsants (n = 7). (cdc.gov)
Cardiac7
- In the emergency department, his electrocardiogram (ECG) was normal, and the results of his first set of cardiac enzyme tests were negative. (hcplive.com)
- For patients considered at-risk at first diagnosis, medically supervised programs such as cardiac rehabilitation and physician-directed, home-based programs are recommended. (aafp.org)
- 5,6 Prior studies have also shown that Asian patients with HF with mildly reduced ejection fraction (HFmrEF) represent a distinct HF phenotype riddled with a high burden of cardiovascular diseases such as DM, peripheral vascular disease, and coronary artery disease with distinct major adverse cardiac events outcomes. (annals.edu.sg)
- The Singapore Cardiac Databank Heart Failure (SCDB-HF) registry is a nationwide prospective, observational data collection registry for all consecutive patients ≥21 years of age admitted for heart failure to all Singapore public hospitals. (annals.edu.sg)
- The patient does not report any significant family history of arrhythmias, cardiomyopathy, or sudden cardiac death . (medscape.com)
- Cardiac complications constitute a major cause of postoperative morbidity and mortality in surgical patients. (medscape.com)
- ABSTRACT We aimed to study the prevalence of the side-effects of statins among Iranians patients admitted to a cardiac-specialized hospital and had taken statins prior to hospitalization. (who.int)
Calcium2
- For patients who demonstrate vasospastic angina, the use of nitrate therapy in conjunction with calcium channel blocker therapy may be very effective. (tgh.org)
- By reducing calcium influx into the heart muscle and blood vessels, these medications promote vasodilation and lower blood pressure levels. (novacorp.biz)
Statins2
- Medications known to be unsafe in pregnancy, such as angiotensin-converting enzyme inhibitors and statins, should be discontinued. (nih.gov)
- The most commonly used statins was atrovastatin (99% of the patients). (who.int)
Proton pump inhi4
- Methods - The researchers used administrative databases for the province of Ontario to identify patients initiated on a proton pump inhibitor (PPI), angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) following hospital admission from April 1, 2008 to March 31, 2009. (ices.on.ca)
- Association Between Proton Pump Inhibitor Use and Risk of Progression of Chronic Kidney Disease. (janusinfo.se)
- There is emerging evidence of various adverse effects of chronic proton pump inhibitor (PPI) therapy. (medscape.com)
- A recent in vitro study found that prolonged exposure to the proton pump inhibitor (PPI) esomeprazole impaired endothelial function and accelerated human endothelial senescence by reducing telomere length. (medscape.com)
Diabetes26
- We describe here the rationale and methods of patient-centred care, using the examples of diabetes and asthma. (mja.com.au)
- Using an online random allocation sequence, 28 patients with type 2 diabetes (metformin and diet controlled) were randomised to 12 weeks of HIIT (n = 14) or standard care ( n = 14). (constantcontact.com)
- PURPOSE We wanted to describe how primary care clinicians care for patients with type 2 diabetes. (annfammed.org)
- METHODS We undertook a cross-sectional study of 95 primary care clinicians and 822 of their established patients with type 2 diabetes from 4 practice-based, primary care research networks in the United States. (annfammed.org)
- Patients completed a self-administered questionnaire about their care, and medical records were reviewed for complications, treatment, and diabetes-control indicators. (annfammed.org)
- RESULTS Participating clinicians (average age, 45.7 years) saw an average of 32.6 adult patients with diabetes per month. (annfammed.org)
- Patients (average age, 59.7 years) reported a mean duration of diabetes of 9.1 years, with 34.3% having had the disease more than 10 years. (annfammed.org)
- Nearly one half (47.5%) of the patients had at least 1 diabetes-related complication, and 60.8% reported a body mass index greater than 30. (annfammed.org)
- CONCLUSIONS Only modest numbers of patients achieve established targets of diabetes control. (annfammed.org)
- 1 Patients with type 2 diabetes often have acute or chronic comorbid health problems that force the clinician to prioritize and address the most pressing or symptomatic problems first. (annfammed.org)
- and medical record reviews to determine medications used for diabetes and cardiovascular risk factor control, indicators of glycemic control, and diabetes-related complications. (annfammed.org)
- Our purpose was to describe the processes and outcomes of care of type 2 diabetes achieved by clinicians and their patients in member practices from 4 practice-based research networks (PBRNs). (annfammed.org)
- In particular, we examined practice design strategies for diabetes care, the composition of the health care team, the complexity of the health problems experienced by patients with type 2 diabetes (including comorbid conditions), control of diabetes (including cardiovascular risk-factor control), and the spectrum of treatment provided by their clinicians. (annfammed.org)
- In patients with type 1 diabetes, insulin detemir may be used with another type of insulin (a short-acting insulin). (medlineplus.gov)
- In patients with type 2 diabetes, insulin detemir also may be used with another type of insulin or with oral medication(s) for diabetes. (medlineplus.gov)
- Using medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. (medlineplus.gov)
- We also found a potential association havior among nonhospitalized patients and ex- between hospitalization and high hemoglobin A1c levels plore the relationships between hospitalization and in persons with diabetes. (cdc.gov)
- Rosiglitazone (Avandia) should not be initiated in patients with diabetes mellitus who have stable IHD. (aafp.org)
- Type 2 diabetes mellitus (DM) is a risk factor for cardiovascular diseases and is common among patients undergoing coronary artery bypass grafting (CABG) surgery. (springer.com)
- Currently, overall cardiovascular disease affects approximately 32.2% of all type 2 diabetes mellitus (DM) patients worldwide, while cardiovascular disease is a major cause of mortality among people with type 2 DM, accounting for approximately half of all deaths [ 1 ]. (springer.com)
- The impact of sex and diabetes mellitus (DM) on patients with heart failure with mildly reduced ejection fraction (HFmrEF) is not well elucidated. (annals.edu.sg)
- Optimization of glycemic control, medication regimens, and careful attention to comorbid conditions can help mitigate these risks and ensure quality diabetes care before, during, and after pregnancy. (nih.gov)
- It is well known that patients and management patterns of diabetes. (who.int)
- Page 2 of 9 angiotensin-converting enzyme inhibitors if appropriate, smoking cessation, physical activity, weight management, and diabetes management (4,9). (cdc.gov)
- Patients with type 2 diabetes from the Fremantle Diabetes Study Phase II and on stable renin-angiotensin system blocking therapy were divided into those remaining untreated with a PPI (group 1, n = 686), on PPI therapy throughout (group 2, n = 174), and commencing (group 3, n = 109) or discontinuing regular PPI therapy (group 4, n = 67) during the 2 years between assessments. (medscape.com)
- [ 9 ] It can be hypothesized, therefore, that patients with type 2 diabetes initiating PPI therapy will manifest a subsequent increase in urinary albumin excretion that will persist after withdrawal of treatment. (medscape.com)
Nephropathy1
- Diagnosis is suggested by development of nephrotic syndrome, particularly in patients who have potential causes of membranous nephropathy. (msdmanuals.com)
Symptoms8
- The study focused on mild to moderate chronic heart failure patients who had weakening function in the heart's left ventricle and symptoms of heart failure, which occurs when the ventricle can no longer pump enough blood to the body's other organs. (medindia.net)
- This summary presents recommendations related to risk factor modification (including strategies of unproven benefit), medical therapies to prevent myocardial infarction and death and to relieve symptoms, and alternative therapies for relief of symptoms in patients with stable IHD. (aafp.org)
- The full guideline contains additional recommendations related to patient education, revascularization to improve survival and symptoms, and patient follow-up. (aafp.org)
- Common symptoms of a mild case of COVID-19 include fever and body aches, which can be relieved by taking OTC medications. (safemedication.com)
- She has not taken any medications for her symptoms outside of her chronic angiotensin-converting enzyme (ACE) inhibitor and statin therapy. (medscape.com)
- In these patients VASOTEC improves symptoms, increases survival, and decreases the frequency of hospitalization (see CLINICAL PHARMACOLOGY , Heart Failure , Mortality Trials for details and limitations of survival trials ). (rxlist.com)
- We are now the highest volume center for CMD diagnosis and therapy in the state of Florida and top three in the nation, and routinely track our quality with pre- and post- diagnosis assessment of patient symptoms. (tgh.org)
- Some patients may require medications in addition to lifestyle and risk factor management to treat symptoms, reduce recurrent events, and improve quality of life. (tgh.org)
Comorbidities2
- 3-5 Most HF patients have comorbidities. (dovepress.com)
- T2DM) is increasing, currently affecting around 425 required to provide more accurate information about the million patients and is estimated to increase to 629 mil- incidence and prevalence of the disease, comorbidities, lion patients by 2045 ( 1 ). (who.int)
Unable to tolerate2
- Owing to survival benefit in patients with left ventricular systolic dysfunction, patients should be initiated on an ACE inhibitor or, if unable to tolerate, an ARB. (medscape.com)
- For patients unable to tolerate ACE inhibitors. (medscape.com)
SGLT23
- SGLT2 Inhibitors in Acute Heart Failure, The Earlier The Better? (medscape.com)
- Tell me, why did we think a sodium-glucose cotransporter 2 (SGLT2) [inhibitor] would do anything in acute heart failure? (medscape.com)
- When we looked at the space of acute heart failure, as you just laid out, we know that starting an SGLT2 inhibitor in the ambulatory setting or at hospital discharge and continuing it chronically has widespread benefit across patients, regardless of ejection fraction. (medscape.com)
Tolerate2
- Most patients tolerate these drugs well, with minimal reports of adverse effects. (novacorp.biz)
- Patients with chronic peripheral artery disease may tolerate longer ischemia time due to presence of collateral circulation. (bvsalud.org)
Chronic disease3
- More recent drivers of patient-centred care include economic constraints on healthcare, reduced hospital stays, increases in shared care and a broadened community base for chronic disease management. (mja.com.au)
- Patient-centred care is an important and evidence-based concept for improving health outcomes for people with chronic disease in primary-care practice. (mja.com.au)
- This is a challenge, because real innovation and change require political commitment, which is sometimes slow to be implemented in health services, even though the evidence for patient-centred approaches to chronic disease management is already strong. (mja.com.au)
Regimens1
- as monotherapy for the treatment of those patients who have received at least two chemotherapy regimens for their metastatic disease. (who.int)
Treatment27
- Angiotensin-converting enzyme inhibitors dose optimizations (ACEIs) are essential to boost the treatment outcome in heart failure patients (HF) with reduced ejection fraction. (dovepress.com)
- Nowadays, therapeutic policies have been deliberated to counter the progression of heart failure and to increase 'long term lives by using ACEIs for HF patients, which is measured currently as one of the important steps towards effective treatment of patients with HF. (dovepress.com)
- The main objective of our study was to investigate the impact of DM type 2, and its treatment subgroups, on short- and long-term mortality in patients with acute coronary syndrome (ACS) who undergo CABG. (springer.com)
- Multivariable analysis showed that DM increased the mortality hazard by 1.61-fold, and insulin treatment among the diabetic patients increased the mortality hazard by 1.57-fold. (springer.com)
- While type 2 DM did not influence the in-hospital mortality hazard, we showed that the presence of DM among patients with ACS referred to CABG, is a powerful risk factor for long-term mortality, especially when insulin was included in the diabetic treatment strategy. (springer.com)
- Test your diagnostic and treatment skills using the following patient scenario and corresponding questions. (medscape.com)
- What Medicine is used for: This medication is used in the treatment of heart failure. (kkh.com.sg)
- Nevertheless, patients still need individualized treatment, the document stresses. (the-hospitalist.org)
- This article will elaborate the pros and cons of a two-drug regime at the start of treatment in newly diagnosed hypertensive patients, and whether the benefits outweigh the potential risks. (escardio.org)
- This protection is not short-lived, as fewer cardiovascular events were observed after one year in hypertensive patients started with combination treatment compared to those with monotherapy [7]. (escardio.org)
- While smaller studies have looked at the utility of these commonly-used heart medications in guarding against anthracycline-induced cardiotoxicity, this trial is one of the first and the largest to date to test whether these drugs can prevent trastuzumab-related heart damage and prevent the need to discontinue a potentially life-saving treatment. (acc.org)
- Patients were randomly assigned to receive once daily lisinopril (10 mg), carvedilol (10 mg Coreg CR) or placebo and were followed for two years (the year of active treatment with trastuzumab and the year that followed). (acc.org)
- Additionally, we are part of the Discover INOCA study, a registry evaluating the natural history, diagnosis, and treatment course of patients diagnosed with CMD. (tgh.org)
- After diagnosis, we are committed to providing personalized medical therapy and working with each patient to develop a treatment plan that meets their specific needs and goals. (tgh.org)
- Our role in the Discover INOCA study and some of our own research efforts will help define the diagnostic and treatment approaches to CMD management for future patients. (tgh.org)
- Adults aged 60 or older should only take blood pressure medication if their blood pressure exceeds 150/90, which sets a higher bar for treatment than the current guideline of 140/90, according to the report, published online Dec. 18 in the Journal of the American Medical Association. (healthinternetwork.org)
- They did have a control group, although patients were not assigned to the treatment and control groups randomly. (rothausmd.com)
- Patients should consult healthcare professionals for personalized treatment plans and remain vigilant about potential side effects. (novacorp.biz)
- We report a case of retinal and ophthalmic artery occlusion resulting in ocular ischemic syndrome in a patient with NF1 who had remarkable improvement in retinal perfusion and visual acuity following high-dose corticosteroid treatment. (bvsalud.org)
- 3) Patient has access to and ability to use conventional on-demand treatment for HAE attacks. (who.int)
- 4) If a patient is receiving long-term prophylactic treatment with one of the protocol-allowed therapies, they must have been on a stable dose and regimen for at least 3 months prior to the Screening Visit and be willing to remain on a stable dose and regimen for the duration of the trial. (who.int)
- However, providers and patients may find it helpful to weigh the risks and benefits of any pharmacologic treatment for both pregnant women and the fetus when managing medical conditions before and during pregnancy. (cdc.gov)
- Quality of care includes proper treatment, including lifestyle changes and appropriate medication use. (cdc.gov)
- Bergqvist J, Iderberg H, Mesterton J, Bengtsson N, Wettermark B, Henriksson R. Healthcare resource use, comorbidity, treatment and clinical outcomes for patients with primary intracranial tumors: a Swedish population-based register study. (janusinfo.se)
- Forslund T, Wettermark B, Andersen M, Hjemdahl P. Stroke and bleeding with NOAC or warfarin treatment in patients with non-valvular atrial fibrillation: a population based cohort study. (janusinfo.se)
- Loikas D, Forslund T, Wettermark B, Schenck-Gustafsson K, Hjemdahl P, von Euler M. Increased thromboprophylactic treatment in patients with atrial fibrillation after the introduction of NOACs - an analysis of sex and gender differences. (janusinfo.se)
- Biocon Biologics Ltd), BT-ON014 - in combination with docetaxel for the treatment of those patients who have not received chemotherapy for their metastatic disease - in combination with an aromatase inhibitor for the treatment of postmenopausal patients with hormone-receptor positive MBC, not previously treated with trastuzumab. (who.int)
Ejection fraction6
- These two classes of medications cause vasodilation, neurohormonal modification, and improvement in left ventricular ejection fraction. (medscape.com)
- Patients admitted nationally for HFmrEF (ejection fraction 40-49%) between 2008 and 2014 were included and followed up until December 2016. (annals.edu.sg)
- In clinically stable asymptomatic patients with left ventricular dysfunction (ejection fraction ≤ 35 percent), VASOTEC decreases the rate of development of overt heart failure and decreases the incidence of hospitalization for heart failure (see CLINICAL PHARMACOLOGY , Heart Failure , Mortality Trials for details and limitations of survival trials ). (rxlist.com)
- All study participants had normal heart function measured by ejection fraction and were not already taking an ACE-inhibitor or beta blocker for other medical reasons. (acc.org)
- However, in patients who were treated with anthracyclines, these heart medications were effective in preserving left ventricular ejection fraction-the heart's pumping ability. (acc.org)
- The majority of hospital readmissions for patients with heart failure with reduced ejection fraction are due to volume overload. (providence.org)
Cardiovascular8
- The aim of the European Action on Secondary and Primary Prevention by Intervention to Reduce Events III (EUROASPIRE III) survey was to determine whether the Joint European Societies' guidelines on cardiovascular prevention are being followed in everyday clinical practice and to describe the lifestyle, risk factor and therapeutic management in patients with coronary heart disease (CHD) in Europe. (nih.gov)
- The EUROASPIRE III survey shows that large proportions of coronary patients do not achieve the lifestyle, risk factor and therapeutic targets for cardiovascular disease prevention. (nih.gov)
- We found that use of one or more of these key medications in combination was associated with significant health gains while at the same time being cost-effective or providing a cost-savings," said the study's senior author Dr. Gregg Fonarow, UCLA's Eliot Corday Professor of Cardiovascular Medicine and Science and director of the Ahmanson-UCLA Cardiomyopathy Center at the David Geffen School of Medicine at UCLA. (medindia.net)
- For patients undergoing noncardiac surgery, bleeding and hypotension are frequent and associated with increased mortality and cardiovascular complications. (biomedcentral.com)
- Patients ≥45 years of age undergoing noncardiac surgery, with or at risk of cardiovascular and bleeding complications, are randomized to receive a TXA 1 g intravenous bolus or matching placebo at the start and at the end of surgery. (biomedcentral.com)
- The European Society of Cardiology and the American College of Cardiology, two of the most renowned associations in the cardiovascular field, have reached a consensus on initial two-drug therapy for most patients with persistent blood pressure ≥140/90 mmHg [5]. (escardio.org)
- Risk stratification and cardiovascular protection, therefore, are compulsory in management for all hypertensive patients. (escardio.org)
- Our findings suggest that among women who are only on a standard course of trastuzumab neither carvedilol nor lisinopril seem to make a difference, but for those who had a history of being on anthracycline, these medications can be cardioprotective and should be considered," said Maya E. Guglin, MD, professor of medicine in the Division of Cardiovascular Disease, University of Kentucky, and lead author of the study. (acc.org)
Complications3
- Did you know that discontinuing your high blood pressure medication without consulting your physician during the COVID-19 pandemic may lead to increased complications? (hospitalcima.com)
- What has been confirmed is that when patients suspend the use of these medications, the result is poor pressure control and therefore, potential complications if the patient contracts COVID-19. (hospitalcima.com)
- While all medications come with potential side effects, these blood pressure drugs are known for offering the least amount of complications, allowing individuals to effectively manage their condition while minimizing any adverse reactions. (novacorp.biz)
Renal4
- Used in patients with proteinuria and decreased renal function. (medscape.com)
- In using VASOTEC consideration should be given to the fact that another angiotensin converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen vascular disease, and that available data are insufficient to show that VASOTEC does not have a similar risk (see WARNINGS ). (rxlist.com)
- Worsening renal function in patients with acute heart failure undergoing aggressive diuresis is not associated with tubular injury. (providence.org)
- Time in Therapeutic Range and Outcomes After Warfarin Initiation in Newly Diagnosed Atrial Fibrillation Patients With Renal Dysfunction. (janusinfo.se)
Kidney7
- The early identification and mitigation of modifiable risk factors for the development of chronic kidney disease are important for improved patient outcomes. (ceufast.com)
- This is a major update of an influential set of guidelines for chronic kidney disease patients" at a time when blood pressure control is worsening in the United States, Dr. Foti, a postdoctoral researcher in the department of epidemiology at Johns Hopkins Bloomberg School of Public Health, Baltimore, said in a statement from her institution. (the-hospitalist.org)
- They recommend that diabetics and patients with kidney disease younger than 60 years old be treated in the same way as all other people, regardless of whether their blood pressure rises above 140/90. (healthinternetwork.org)
- These medications are generally well-tolerated and have been shown to have a minimal impact on kidney function. (novacorp.biz)
- Blood Pressure in Chronic Kidney Disease for patients not preparation and measurement protocols adhered to by receiving dialysis represents an update to the KDIGO patients and clinicians. (bvsalud.org)
- The burden of the pressure targets, lifestyle interventions, antihypertensive recommendations on patients and resources, public medications, and specific management in kidney policy implications, and limitations of the evidence are transplant recipients and children. (bvsalud.org)
- Evans M, Carrero JJ, Bellocco R, Barany P, Qureshi AR, Seeberger A, Jacobson SH, Hylander-Rössner B, Rotnitzky A, Sjölander A. Initiation of erythropoiesis-stimulating agents and outcomes: a nationwide observational cohort study in anaemic chronic kidney disease patients. (janusinfo.se)
Nephrotic syndrome1
- Prednisone should be used in patients with nephrotic syndrome and minimal histologic findings. (medscape.com)
Risk10
- There is still considerable potential throughout Europe to raise standards of preventive care in order to reduce the risk of recurrent disease and death in patients with CHD. (nih.gov)
- Likewise, the decreased risk of those taking angiotensin medications may be due in part to the renin-angiotensin system. (madinamerica.com)
- Because of his moderate risk profile, the patient was admitted to the telemetry unit on the medical floor, with a provisional diagnosis of "rule out myocardial infarction [MI]. (hcplive.com)
- This condition requires careful evaluation by the physician, as these patients may be at increased risk of heart attack or stroke. (cedars-sinai.org)
- Risk assessment with a physical activity history is recommended to guide prognosis and prescription for all patients. (aafp.org)
- Aerobic activity should be supplemented by an increase in daily activities, such as walking during breaks at work, gardening, or household activities, to improve cardiorespiratory fitness and motivate patients who are less fit, less active, and at increased risk. (aafp.org)
- They write that nevertheless, one important takeaway from this and other studies "is that isolated [AVR] for AR in the modern era can be performed with very low perioperative risk in appropriately selected patients at high volume centers of excellence. (acc.org)
- Shortening time to control is of the utmost priority to provide timely protection in high-risk patients, whose events can happen at any time in the foreseeable future. (escardio.org)
- 2019 ACC expert consensus decision pathway on risk assessment, management, and clinical trajectory of patients hospitalized with heart failure: a report of the American College of Cardiology Solution Set Oversight Committee. (providence.org)
- Our final list included medications categorized as 'high' risk in at least four of six models (if three data sources) or three of four models (if two data sources). (cdc.gov)
Lisinopril2
- Lisinopril, a synthetic peptide derivative, is an oral long-acting angiotensin converting enzyme inhibitor. (globalrph.com)
- However, in patients who had received or were concurrently receiving anthracycline-based chemotherapy in addition to trastuzumab, the occurrence of heart damage was halved among those taking either the angiotensin converting enzyme inhibitor (ACE-inhibitor) lisinopril or beta blocker carvedilol, compared with placebo after two years of follow-up. (acc.org)
Include2
- Lifestyle factors that can help prevent cardiomegaly include eating a healthy diet, controlling blood pressure, exercise, medications, and not abusing alcohol and cocaine. (wikipedia.org)
- The recommended dietary therapy for all patients should include reducing intake of saturated fats to less than 7% of total calories, reducing intake of trans-fatty acids to less than 1% of total calories, and reducing daily cholesterol intake to less than 200 mg. (aafp.org)
Characteristics1
- We introduce the rare case of a patient with left atrial myxoma (LAM) whose right lower extremity (RLE) suffered from acute ischemia due to tumor fragments, along with a review of the relevant literature, and highlight the clinical characteristics of LAM. (bvsalud.org)
Findings3
- Our findings demonstrate the importance of prescribing these national guideline-directed medical therapies to patients with heart failure. (medindia.net)
- Patients with abnormal findings on their CMD study are followed up in our CMD Medical Clinic to tailor their therapy. (tgh.org)
- Our findings should inform patient and prescriber decisions concerning continued use of these medications during the pandemic. (nihr.ac.uk)
Interventions1
- Fonarow notes that the costs of not effectively taking these key medications would be higher due to increased hospitalizations and need for other interventions. (medindia.net)
Progression1
- 70 mL/min) have shown significant delay of disease progression compared to patients not receiving corticosteroids. (medscape.com)
Outcomes in Patients1
- There is currently no evidence to support an association between ibuprofen and negative outcomes in patients with COVID-19. (safemedication.com)
Drugs3
- Drugs that act directly on the renin-angiotensin system can cause injury and death to the developing fetus. (globalrph.com)
- There were 5, 21 and 9 colorectal cancer patients who took metformin, non-metformin and other antidiabetic drugs, respectively. (aging-us.com)
- However, selecting blood pressure drugs with the least side effects is crucial to ensure the well-being of patients. (novacorp.biz)
Acute decompensated heart failure1
- Physical rehabilitation that begins during the hospital stay and continues for 3 months after also could help frail, older patients who are hospitalized for acute decompensated heart failure with HFpEF, Pastva said, citing her research and that of other groups . (medscape.com)
Coronary9
- Consecutive patients, with a clinical diagnosis of CHD, were identified retrospectively and then followed up, interviewed and examined at least 6 months after their coronary event. (nih.gov)
- citation needed] The most common causes of cardiomegaly are congenital (patients are born with the condition based on a genetic inheritance), high blood pressure (which can enlarge the left ventricle causing the heart muscle to weaken over time), and coronary artery disease. (wikipedia.org)
- IVUS-derived negative remodeling is associated with adverse long-term clinical outcome in stable patients with intermediate coronary artery stenosis. (hindawi.com)
- Accordingly, we sought to investigate the impact of arterial remodeling of intermediate lesions on long-term prognosis in patients with stable coronary artery disease. (hindawi.com)
- Consecutive patients with stable coronary heart disease who received IVUS examination between January 2011 and January 2014 were retrospectively screened. (hindawi.com)
- The study included 1307 patients enrolled from the biennial Acute Coronary Syndrome Israeli Survey between 2000 and 2016, who were hospitalized for ACS and underwent CABG. (springer.com)
- Yet, researchers also noted that patients with COPD, asthma and ILD were less likely to receive coronary revascularization compared with patients without lung conditions. (acc.org)
- examined 748 patients with significant aortic regurgitation (AR) without prior heart surgery, myocardial infarction or overt coronary artery disease between 2006 and 2017. (acc.org)
- 50-65% of patients with angina with non-obstructive coronary artery disease (NOCAD) are believed to have Coronary Microvascular Dysfunction (CMD). (tgh.org)
Stable1
- In addition to following a trial of lifestyle modifications, patients with stable IHD and a blood pressure of 140/90 mm Hg or higher should be treated with antihypertensive drug therapy to achieve goal blood pressure. (aafp.org)
Limb-threaten1
- Dr. Fadden Clinical question: Which is a better approach for patients with chronic limb-threatening ischemia (CLTI): surgery or endovascular therapy? (the-hospitalist.org)
Prognosis2
- Bleeding and hypotension in noncardiac surgery are common and have a substantial impact on patient prognosis. (biomedcentral.com)
- 1 DM has been shown to be a common comorbidity in heart failure (HF) patients ranging from 4.3-28% 2 and when present, portends a poorer prognosis in these patients. (annals.edu.sg)
Methods1
- When medical management comprises more than a single pill, more complex methods of interacting with, and partnering, patients are needed to improve adherence to management, quality of life, and health outcomes. (mja.com.au)
Appropriate medication1
- Effectively managing high blood pressure requires careful consideration when selecting the appropriate medication. (novacorp.biz)
Mortality2
- Overall 30-day mortality rate was similar between DM and non-DM patients (4.2% vs. 4%, p = 0.976). (springer.com)
- However, the researchers state this is the first study to demonstrate that IHD is independently associated with all-cause mortality in patients with ILD. (acc.org)
Researchers3
- Researchers studied the incremental health and cost benefits of three common heart failure medications that are recommended by national guidelines developed by organizations like the American College of Cardiology and American Heart Association. (medindia.net)
- Researchers found that the combination of these medical therapies demonstrated the greatest gains in quality-adjusted life years for heart failure patients. (medindia.net)
- The researchers sought to determine how much public money could be saved on chronic medications if hospitals promoted the initiation of agents with the lowest outpatient formulary prices. (ices.on.ca)
Adult patients2
- We conducted retrospective chart reviews of adult patients with OLP who presented to oral medicine and oral pathology clinics in 2 provinces between September 2016 and January 2020. (jcda.ca)
- All adult patients (≥18 years of age) who presented to the MGH clinic or the Atlantic Oral Surgery & Dental Implant Centre between 1 Sept. 2016 and 31 Jan. 2020 for an oral pathology appointment were screened for eligibility. (jcda.ca)
Clinically2
- But exercise capacity or cardiorespiratory fitness is an independent, clinically meaningful patient outcome. (medscape.com)
- This prospective, randomized, controlled trial enrolled 468 patients at more than 165 centers in North America who were diagnosed with breast cancer and for whom trastuzumab was clinically indicated. (acc.org)
20231
- That was one message at a session on heart failure in older patients at the American Geriatrics Society (AGS) 2023 Annual Scientific Meeting. (medscape.com)
Adverse1
- It is crucial to remember that even medications associated with minimal side effects might still trigger adverse reactions in certain individuals. (novacorp.biz)
Heart failure7
- A large randomized controlled trial (Flolan International Randomized Survival Trial [FIRST]) evaluated the use of epoprostenol infusion with standard of care in patients with advanced heart failure versus standard of care alone. (medscape.com)
- Medications used to treat heart failure are highly cost effective in saving lives and may also provide savings to the health care system. (medindia.net)
- This is one of the first studies analyzing the incremental cost effectiveness of heart failure medications and taking into account the very latest information, including the lower costs of generic versions of the medications. (medindia.net)
- In some scenarios, the medications were actually cost-saving where heart failure patients lives were prolonged at lower costs to the health care system. (medindia.net)
- The study found that up to $14,000 could be spent over a lifetime on a heart failure disease management program to improve medication adherence and still be highly cost effective. (medindia.net)
- Further resources should be allocated to ensure full adherence to guideline directed medical therapies for heart failure patients to improve outcomes, provide high-value care, and minimize health care costs. (medindia.net)
- It is usually used with other medications to treat heart failure, replacing medications that belong to Angiotensin-Converting Enzyme (ACE) inhibitor or Angiotensin Receptor Blocker (ARB) drug classes. (kkh.com.sg)
Consecutive2
- Between 2000 and 2016 (which included 8 consecutive registries), 1307 patients were hospitalized with ACS and underwent CABG and were included in the ACSIS registry. (springer.com)
- Consecutive unique patients who were admitted to the SCDB-HF registry from 1 January 2008 to 31 December 2014 were included. (annals.edu.sg)
Pulmonary2
- What Medicine is used for: Salbutamol is used to relieve breathlessness in patients with asthma or chronic obstructive pulmonary disease (COPD). (kkh.com.sg)
- looked at 31,646 chronic obstructive pulmonary disease (COPD) patients, 60,424 asthma patients and 1,662 interstitial lung disease (ILD) patients, all of whom were admitted to seven National Health Service hospitals in England between Jan. 1, 2000 and March 31, 2013. (acc.org)
Blood pressure medications1
- It is important to acknowledge that although these blood pressure medications generally have minimal side effects, individual responses may vary. (novacorp.biz)
Survival1
- Kaplan-Meier survival curves per antihypertensive (the upper panel) and antidiabetic (the lower panel) medications. (aging-us.com)
Cough1
- May induce a more complete inhibition of the renin-angiotensin system than ACE inhibitors, do not affect the response to bradykinin, and are less likely to be associated with cough and angioedema. (medscape.com)
Healthcare10
- Given the high healthcare value provided by these medical therapies for health failure, reducing patient costs for these medications or even providing a financial incentive to promote adherence is likely to be advantageous to patients as well as the health care system," said Fonarow. (medindia.net)
- Pharmacists are medication experts and the most accessible healthcare providers. (safemedication.com)
- As the number of elderly patients increases, nurses and other healthcare providers must become knowledgeable about the special healthcare needs of the geriatric population. (netce.com)
- In support of improving patient care, NetCE is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. (netce.com)
- CEUFast Inc. and the course planners for this educational activity do not have any relevant financial relationship(s) to disclose with ineligible companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. (ceufast.com)
- As such, consulting a healthcare professional before initiating any medication is vital. (novacorp.biz)
- INTRODUCTION: Women and healthcare providers lack adequate information on medication safety during pregnancy. (cdc.gov)
- We developed a list of medications of greatest concern during pregnancy to help healthcare providers counsel reproductive-aged and pregnant women. (cdc.gov)
- DISCUSSION: This evidence-based list could be a useful tool for healthcare providers counseling reproductive-aged and pregnant women about medication use during pregnancy. (cdc.gov)
- Schmidt-Mende K, Andersen M, Wettermark B, Hasselström J. Educational intervention on medication reviews aiming to reduce acute healthcare consumption in elderly patients with potentially inappropriate medicines -A pragmatic open-label cluster randomized controlled trial in primary care. (janusinfo.se)