Mediastinal tumors resection. Medical search. Frequent questions

Surgical management of primary mediastinal germ cell tumors. (epnet.com)
Available at: https://www.ctsnet.org/article/surgical-management-primary-mediastinal-germ-cell-tumors. (epnet.com)
Germ cell tumors. (epnet.com)
Available at: https://www.brighamandwomens.org/lung-center/diseases-and-conditions/germ-cell-tumors. (epnet.com)
The only known risk factor for extragonadal germ cell tumors is Klinefelter syndrome (47XXY), which is associated with mediastinal nonseminomatous germ cell tumors, which are characterized by their location on the midline from the pineal gland to the coccyx. (medscape.com)
[ 1 , 2 ] In extragonadal germ cell tumors, no evidence of a primary malignancy is present in either the testes or ovaries by radiologic imaging or physical examination. (medscape.com)
Controversy remains regarding the origin of extragonadal germ cell tumors. (medscape.com)
The classic theory suggests that germ cell tumors (GCTs) in these areas are derived from local transformation of primordial germ cells misplaced during embryogenesis. (medscape.com)
According to this theory, the differences in phenotypes expressed by mediastinal germ cell tumors (MGCTs) and gonadal germ cell tumors may be explained by differences in the cellular environment between the gonad and the anterior mediastinum. (medscape.com)
Some retroperitoneal extragonadal germ cell tumors may represent metastases from a testicular cancer , with subsequent spontaneous necrosis of the primary tumor. (medscape.com)
The association of Klinefelter syndrome and mediastinal nonseminomatous germ cell tumors is now well recognized. (health.am)
Four of 22 consecutive patients (18%) treated at Indiana University for primary mediastinal germ cell tumors had karyotypic confirmation of Klinefelter syndrome, and an additional patient had clinical features. (health.am)
The average age of patients with Klinefelter syndrome who develop extragonadal germ cell tumors is approximately 18 years, 10 years younger than the median age of those developing this tumor in the absence of Klinefelter syndrome. (health.am)
Increasing evidence indicates that many individuals who develop germ cell tumors have underlying germ cell defects. (health.am)
Many patients with extragonadal germ cell tumors have histories of infertility, and testicular biopsy in these patients shows various abnormalities, including decreased spermatogenesis, peritubular fibrosis, and interstitial edema. (health.am)
In addition, patients who are successfully treated for extragonadal germ cell tumors have a markedly increased risk of developing a subsequent testicular germ cell tumor. (health.am)
These data suggest that either a congenital or an acquired germ cell defect contributes not only to defective spermatogenesis but also to the development of extragonadal germ cell tumors. (health.am)
Hematologic Neoplasia A unique association between mediastinal nonseminomatous germ cell tumors and a variety of hematologic neoplasms is now well described. (health.am)
In a series of 635 patients with extragonadal germ cell tumors, 17 patients developed hematologic malignancies at a median of 6 months after the extragonadal germ cell tumor was diagnosed. (health.am)
All hematologic neoplasms developed in the 287 patients with mediastinal nonseminomatous germ cell tumors, for a 2% incidence in this group. (health.am)
Foci of malignant lymphoblasts have been recognized histologically in several mediastinal germ cell tumors. (health.am)
However, the specific association of leukemias and other hematologic neoplasms with mediastinal nonseminomatous germ cell tumors, rather than with all germ cell tumors, remains unexplained. (health.am)
In addition to hematologic neoplasia, several cases of idiopathic thrombocytopenia in association with mediastinal nonseminomatous germ cell tumors have been reported. (health.am)
Neuron-specific enolase (NSE) was measured with an enzyme-immunoassay in sera from 54 patients with malignant (24 cases) and benign (30 cases) germ cell tumors of ovarian origin. (keyopinionleaders.com)
Literature suggests that the only known risk factor for extragonadal germ cell tumors (EGCTs) is Klinefelter syndrome (47XXY), which is associated with mediastinal nonseminomatous germ cell tumors. (medscape.com)
Extragonadal germ cell tumors produce a rich symptomatology and may reach large volumes if they arise in silent areas. (medscape.com)
Hematologic malignancies are frequently associated with mediastinal germ cell tumors. (medscape.com)
Highly differentiated yolk-sac tumors make up 30% of mediastinal germ cell tumors, providing a possible basis for this association. (medscape.com)
The balance of the p53-mdm2 interaction has been shown to be disrupted in intracranial germ cell tumors (ICGCTs). (medscape.com)
Sacrococcygeal and cervicofacial teratomas represent the most common sites for extragonadal germ cell tumors in neonates and early childhood and account for more than 70% of teratomas in most series (2). (paedcro.com)

Anterior mediastinal solitary fibrous tumor resection by da Vinci® Surgical System in obese patient. (omicsdi.org)
The treatment of choice is the extensive surgical resection that is curative for most benign lesions.We present the case of solitary fibrous tumor of the anterior mediastinum in obese patient (BMI: 34.3) undergoing complete surgical resection by robotic-assisted thoracoscopic surgery with da Vinci® Surgical System.Robotic-assisted thoracoscopic surgery with da Vinci® Surgical System is an interesting option for obese patient, at higher risk for deep sternal wound infection. (omicsdi.org)
It recurred on the neck area 4 months after excision and the lesion was removed with surgical resection again. (nih.gov)
He underwent surgical resection of the lesion. (springeropen.com)
The operation was initially performed as video-assisted thoracic surgery (VATS), but the surgical approach was converted to a thoracotomy because the tumor was tightly attached to the chest wall. (springeropen.com)
In 1939, Alfred Blalock reported the first case in which symptoms of myasthenia gravis were completely relieved by removal of a thymic tumor, thus initiating a surgical option in the treatment of that disease. (medscape.com)
Surgical Resection Alone Is Effective Treatment For Ovarian Immature Teratoma In. (keyopinionleaders.com)
Patients with Stage III NSCLC may be deemed inoperable because of patient factors (the patient's respiratory function or co-morbidities may preclude operative intervention or the patient may choose not to proceed with surgery) or tumour factors (the extent or location of gross disease might make surgical resection technically impossible, for example left sided tumours with mediastinal nodes to the right of the aorta, N3 nodal involvement and most T4 tumours). (cancer.org.au)
Colorectal cancer with liver metastases: Neoadjuvant chemotherapy, surgical resection first or palliation alone? (wjgnet.com)
Khan K, Wale A, Brown G, Chau I. Colorectal cancer with liver metastases: Neoadjuvant chemotherapy, surgical resection first or palliation alone? (wjgnet.com)
Four retroperitoneal and 2 mediastinal tumors were diagnosed and all infants survived surgical therapy. (paedcro.com)
The benign form may be cured by surgical resection, whereas the malignant tumor is aggressive, spreading by local extension, and usually encasing the lung and mediastinum. (uab.edu)

Similarly to laparoscopy, VATS has enjoyed widespread use for technically straightforward operations such as pulmonary decortication, pleurodesis, and lung or pleural biopsies, while more technically demanding operations such as esophageal operations, mediastinal mass resections, or pulmonary lobectomy for early stage lung cancer, have been slower to catch on and have tended to remain confined to selected centers. (wikipedia.org)

All lung lesions were removed using a wedge resection. (go.jp)
Do not insist on wedge resection or patch reconstruction when a sleeve with end-to-end anastomosis can ensure a larger caliber and a straight arterial axis. (sts.org)
She was taken to the operating room and underwent a wedge resection of her small lung nodule, as it was too small to reach by needle, and this confirmed an adenocarcinoma. (cancergrace.org)

The tumor was definitively diagnosed pathologically from paraffin sections as a benign esophageal leiomyoma. (omicsdi.org)
A comparison of the intrathoracic malignant neurogenic tumors and the benign neurogenic tumors resected at our institution revealed no meaningful differences distinguishing malignant from benign neurogenic tumors prior to surgery. (springeropen.com)
Additionally, we present a comparison of the clinical characteristics and outcomes of these patients and those of patients with benign neurogenic tumors (BNTs) resected at our institution. (springeropen.com)
These include lobectomies, esophagectomies, operations for benign esophageal disease, and resection of mediastinal tumors. (clevelandclinic.org)
Muesse's clinical interests include lung cancer, esophageal cancer, benign esophageal diseases including achalasia and paraesophageal hernias, chest wall resection and reconstruction, hyperhidrosis, and mediastinal tumors. (uams.edu)
This tumor may be benign or malignant. (uab.edu)

Extragonadal germinal cell tumors (EGGCTs) are rare tumors that predominantly affect young males. (medscape.com)

To remove the tumor, the doctor will make one large, central incision in the chest, an incision between the ribs, or several small incisions. (epnet.com)
Chest wall reconstruction is usually performed when there is an infections after open heart surgeries or chest wall defects after resection of tumors. (drnjithendran.com)
Pancoast tumors are a subset of lung cancers that invade the apical chest wall. (medscape.com)
The bulk of a true Pancoast tumor is extrathoracic, originating in an extreme peripheral location with a plaquelike extension over the lung apex and principally involving the chest wall structures rather than the underlying lung parenchyma. (medscape.com)
The tumor may invade the bony structures of the chest, including the first or second thoracic vertebra or the first, second, or third rib. (medscape.com)
Chest computed tomography (CT) and magnetic resonance imaging (MRI) revealed a posterior mediastinal tumor (Figure 1 A,B). The patient was asymptomatic and had no signs of intraspinal canal extension on the imaging studies. (springeropen.com)
Tumors that occur in this area of the chest can present in many different ways clinically and can produce many different pathologic processes. (medscape.com)
The tumor is usually visible along the lateral chest wall, however, mediastinal or concentric pleural thickening may be seen in extensive disease. (uab.edu)
MRI scan can accurately identify lymph node and blood vessels, and to three-dimensional observation with a large mediastinal tumor blood vessels and the heart of the relationship, after the tumor, the tumor can be observed and the relationship between the spine and spinal cord, and observe whether the tumor is clear violation of cardiovascular, chest wall, lungs and spine. (cancerlive.net)

Solitary fibrous tumors are uncommon soft tissue tumors initially reported only in the pleura but, in recent years, they have been described at many extra pleural sites, such as mediastinum. (omicsdi.org)
She received right upper lobe lobectomy, mediastinal lymph node dissection, pleural adhesion cauterization, phrenic nerve compression, and ninth-rib resection in September 2019 in a local hospital. (frontiersin.org)
Mesothelioma is the most common primary tumor of the pleural space. (uab.edu)
Moreover, the fibrous nature of the tumor has given rise to various other names, such as pleural fibroma, submesothelial fibroma, and localized fibrous tumor. (medscape.com)

Thorascopic removal of intrathoracic neurogenic tumors: a combined Chinese experience. (epnet.com)
Although its overall incidence remains unclear, it likely accounts for less than 1% to 2% of mediastinal neurogenic tumors [ 2 ]. (springeropen.com)
He also described successful removal of neurogenic tumors from the posterior mediastinum and described several types of thymic tumors. (medscape.com)
In 1995, video-assisted removal of neurogenic tumors was reported in combination with microneurosurgical techniques. (medscape.com)
Recently, isolated reports of robotic resection of neurogenic tumors have also been reported. (medscape.com)

Superior Vena Cava Resection and Reconstruction with Resection of Primary Lung Cancer and Mediastinal Tumor. (bvsalud.org)
More extensive defects of the PA (Table 1) may require reconstruction by a patch (of various materials), sleeve resection and reconstruction by end-to-end anastomosis, or sleeve resection and reconstruction by a prosthetic conduit. (sts.org)

These apical lung tumors tend to be locally invasive early. (medscape.com)
The pulmonary artery (PA) can be infiltrated by primary lung tumors or by metastatic hilar-mediastinal lymph nodes with extracapsular extension. (sts.org)
All the imaging studies stored in the electronic file system were reviewed, including plain radiographs and magnetic resonance imaging MRI studies, but the reviewers have particularly focused on the description of CT findings, which parazitii primii 10 ani currently the neuroendocrine cancer symptoms accurate radiological method and most commonly utilized in the evaluation of lung tumors. (adventube.ro)

and VATS lobectomy/mediastinal lymphadenectomy for lung cancer. (wikipedia.org)
Lobectomy with mediastinal lymphadenectomy is the standard of care for the treatment of Author Manuscript early-stage non-small cell lung cancer (NSCLC). (cdc.gov)

P2.17-003 - Is Complete Resection Mandatory for Mediastinal Germ Cell Tumor Which Shows Severe Adhesion to Greater Vessels? (iaslc.org)
Oncologically complete resection should be primarily pursued. (sts.org)

Heuer noted that at that time dermoid cysts and teratomas were the most commonly found tumors of the mediastinum. (medscape.com)
Purpose: Teratomas, the most common tumor affecting neonates, has an estimated incidence of 1 in 20,000 to 30,000 live births. (paedcro.com)
Results: Teratomas, the most common neoplasm in neonates and young infants accounted for over 40% of all solid tumors observed in this age population. (paedcro.com)
Teratomas are unusual tumors occurring with a reported incidence of one in 30,000 live births (1). (paedcro.com)

Video-assisted thoracoscopic surgery (VATS) is being used to treat esophageal submucosal tumors (SMTs) all over the world. (omicsdi.org)
Minimally invasive or VATS lung resections can be performed through one (Uniportal VATS), two or three incisions. (ests.org)

This surgery can help to remove the tumors to ease any problems they may have caused. (epnet.com)
Video assisted thoracoscopic surgery for mediastinal extramedullary haematopoiesis. (wikipedia.org)
Background: We report our experience of cardiac surgery with concomitant pulmonary resection, based on analysis of the results. (go.jp)
Conclusion: Rates of operative mortality and morbidity following cardiac surgery with concomitant pulmonary resection were favorable, and early to midterm results were acceptable. (go.jp)
Mediastinal lymphadenectomy remains the gold standard in lung cancer surgery including early stage NSCLC. (muni.cz)
In 1897, Milton wrote extensively on mediastinal surgery using the median sternotomy approach. (medscape.com)
Another thoracic surgery application of near-infrared intraoperative fluorescence imaging is in lung mapping for robotically assisted pulmonary resection. (clevelandclinic.org)
Concerning thoracic surgery, robotic technologies are currently used to perform lung, lymph nodes, and mediastinal tumor resections. (louvainmedical.be)

Although other tumors may have a similar clinical presentation because of their location at the thoracic inlet, the most common cause is believed to be a bronchogenic carcinoma arising in or near the superior sulcus and invading adjacent extrathoracic structures by direct extension. (medscape.com)
The tumor can also invade the first or second thoracic vertebral bodies or intervertebral foramina. (medscape.com)
The mediastinum is limited bilaterally by the mediastinal parietal pleura and extends from the diaphragm inferiorly to the level of the thoracic inlet superiorly. (medscape.com)

1 The most frequent primary tumor types of anterior mediastinal masses are thymic tumors and lymphoma, with approximate proportions of 35% and 25% among mediastinal lesions, respectively. (allenpress.com)

Bevacizumab also may stop the growth of non-small cell lung cancer by blocking the growth of new blood vessels necessary for tumor growth. (ucsf.edu)

After the lung resection the systematical mediastinal lymphadenectomy was performed. (muni.cz)

The currently accepted nomenclature is solitary fibrous tumor. (medscape.com)

This often poses diagnostic challenges because of the complexity of the mediastinal anatomic structures. (allenpress.com)
An understanding of the embryology of this area and of the anatomic relationships of the normal structures within the mediastinum is essential in the proper determination of the exact nature of a mass or tumor located in this area. (medscape.com)
Low-grade tumors may recur and infiltrate adjacent structures. (medscape.com)

The primary endpoint of the study is OS, and secondary endpoints include progression-free survival (PFS) and objective response rate (ORR) as assessed by blinded independent central review (BICR) per Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 modified for mesothelioma, safety and quality of life. (merck.com)

Recent evidence indicates that the hematologic neoplasms in this setting are not treatment related, but rather arise from clones of malignant lymphoblasts or myeloblasts contained within the mediastinal germ cell tumor. (health.am)
Neurogenic tumor is a common intrathoracic neoplasm, representing approximately 20% of all adult and 35% of all pediatric mediastinal neoplasms [ 1 ]. (springeropen.com)

More importantly, several patients have had an identical chromosomal abnormality (an isochromosome of the short arm of chromosome 12) in the neoplastic cells from the mediastinal germ cell tumor and the hematologic neoplasm, providing strong evidence for a common origin. (health.am)
To design a study with a fairly small sample size and short follow-up period, the conclusion was reached that the study should be conducted in patients who had undergone endoscopic mucosal resection (EMR) for early gastric cancer because they have the highest incidence of recurrent gastric cancer. (go.jp)
We present three patients with intrathoracic malignant neurogenic tumor. (springeropen.com)
Because there is no effective chemotherapeutic regimen for intrathoracic malignant neurogenic tumor, all three patients received high-dose chemotherapy followed by hematopoietic stem cell transplantation. (springeropen.com)
After resection 2 patients had evidence of unilateral recurrent laryngeal nerve injury, and 2 required thyroid hormone replacement. (paedcro.com)
We know from published series of patients (essentially single institution experiences) that some very unusual patients with metastatic NSCLC can survive 5 years or more with aggressive treatment of the lung tumor and the metastatic site. (cancergrace.org)
For example, patients with a solitary brain metastasis or adrenal gland metastasis have up to a 10-15% chance of long term survival in some series if the lung cancer and metastatic tumor can be removed. (cancergrace.org)
On the other side of things, patients with mediastinal nodal involvement (N2 or N3) or who have metastasis to the bone, to my knowledge, have historically shown little or no chance of cure with aggressive treatment based upon published series on lung cancer (this is not true in other cancers such as breast cancer). (cancergrace.org)
We performed polymerase chain reaction analysis, for Mycobacterium species 16S rRNA, rpoB , and IS 6110 sequences, on 25 tissue specimens from patients with sarcoidosis and on 25 control tissue specimens consisting of mediastinal or cervical lymph nodes and lung biopsies. (cdc.gov)
For this study, we selected paraffin-embedded tissue specimens from patients who had had mediastinal or cervical lymph node resection from 1991 to 2001. (cdc.gov)

We opened the superior mediastinal pleura cranially and caudally from the arch of the azygos vein and expanded the superior mediastinum after dividing the azygos vein. (omicsdi.org)

These lesions are accessible through endoscopic/endobronchial ultrasound-guided or computed tomography-guided fine-needle aspiration cytology and represent a wide range of primary and metastatic tumors. (allenpress.com)
To provide an updated review on the fine-needle aspiration cytology of mediastinal tumors/lesions, with an emphasis on diagnostic challenges. (allenpress.com)
Fine-needle aspiration cytology plays a vital role in evaluation of mediastinal lesions. (allenpress.com)
Fine-needle aspiration cytology (FNAC) was first introduced by Martin and Ellis 4 and has been used as an easy and safe procedure for diagnosing primary and metastatic mediastinal diseases. (allenpress.com)

The diagnosis was confirmed between 1.5 and 34 months (average, 11 months) with one child presenting with metastatic tumor at 10 months of age. (paedcro.com)

Identified by next-generation sequencing (NGS), EGFR G724S was found from a primary and a secondary tumor biopsy, respectively. (frontiersin.org)

We report a case of malignant proliferating trichilemmal tumor showing multiple distant metastases. (nih.gov)
There was evidence of multiple metastases on CNS and mediastinal lymph nodes after 6 months. (nih.gov)

However, this technique is difficult when the tumor is large and located on the left side wall of the esophagus, within the upper mediastinum. (omicsdi.org)
These tumors can be found anywhere on the midline, particularly the retroperitoneum, the anterior mediastinum, the sacrococcyx, and the pineal gland. (medscape.com)
Several tumors of neurogenic origin can occur in the mediastinum. (medscape.com)
Any discussion of masses and tumors of the mediastinum requires delineation of the boundaries of that area. (medscape.com)
When defining the location of specific mediastinal masses, the portion of the thorax defined as the mediastinum extends from the posterior aspect of the sternum to the anterior surface of the vertebral bodies and includes the paravertebral sulci. (medscape.com)

Tumors in this area can put pressure on heart, lungs, spine and esophagus. (epnet.com)
An MRI confirmed that there was a large tumor in the lower spine, and a surgeon went in and took a piece of the bone to determine the cause. (cancergrace.org)
How could such a small tumor, less than 1cm in size, be the cause of the spine tumor? (cancergrace.org)

Because some mediastinal tumors and other masses are most often found in particular mediastinal locations, many authors have artificially subdivided the area for better descriptive localization of specific lesions. (medscape.com)

Mediastinal tumors/lesions are frequently encountered in daily cytopathology practice. (allenpress.com)
Tumors metastatic to mediastinal lymph nodes represent the most common mediastinal lesions and must be differentiated from primary lesions. (allenpress.com)

One patient with local recurrence underwent radiation therapy, but the recurrent tumor continued to progress. (springeropen.com)
One child with an immature SCT had recurrent tumor at a local site. (paedcro.com)

She also underwent mediastinal nodal sampling, which quite surprisingly showed involvement of several lymph nodes. (cancergrace.org)

Neuroendocrine tumors. (adventube.ro)
Primary neuroendocrine tumors of the lung NTLs originate either from Kulchitzky cells, neuroepithelial bodies or from pluripotent stem cells which are present in the bronchial mucosa, with similar pathological features, and being capable of producing and secreting peptide hormones and neuroamines 2. (adventube.ro)
Only histopathologically confirmed cases of primary neuroendocrine tumors of the lung were included in the present study. (adventube.ro)

At presentation, 70% of SCT were mature teratoma, 20% were immature teratoma and 10% had endodermal sinus tumor (EST). (paedcro.com)

the diagnosis of mediastinal tumors in different parts of the tumor is so important that radiology is a major means. (cancerlive.net)

The total console times were 189 min for the juxta-anal purse-string suture placement, partial intersphincteric resection, and bottom-up mesorectal dissection to where it meets the peritoneal reflection and 43 min for the abdominal procedure. (omicsdi.org)

In addition, tumour motion is not uniform in three dimensions and the degree of movement may be dependent upon the location of the tumour in the lungs and on the compliance of the thorax and lung parenchyma. (cancer.org.au)

In 1893, Bastinelli described the removal of an anterior mediastinal dermoid cyst. (medscape.com)

Anatomy11

Diseases62

Chemicals and Drugs4

Analytical, Diagnostic and Therapeutic Techniques and Equipment44

Psychiatry and Psychology1

Phenomena and Processes4

Disciplines and Occupations1

Information Science3

Health Care12

Germ cell t30

Surgical12

Decortication1

Wedge resection3

Benign6

Cell tumors1

Chest9

Pleural4

Neurogenic tumors5

Reconstruction2

Lung tumors3

Lobectomy2

Complete resection2

Teratomas4

VATS2

Surgery8

Thoracic3

Thymic tumors1

Blood vessels1

Lymphadenectomy1

Solitary fibrous tumor1

Structures3

Solid tumors1

Neoplasms2

Patients10

Pleura1

Cytology4

Metastatic tumor1

Biopsy1

Metastases2

Mediastinum5

Spine3

Masses1

Lesions2

Recurrent tumor2

Underwent1

Neuroendocrine3

Immature Teratoma1

Diagnosis1

Dissection1

Lungs1

Anterior1