Frequent caffeine consumption reduces gray matter volume in areas of the right medial temporal lobe, including the hippocampus. (neurosciencenews.com)
Activity in the hippocampus and entorhinal cortex can be driven from the medial septum (MS), and the NI projects to all these centers, where a prominent pattern of activity is theta rhythm, which is related to spatial memory processing. (listlabs.com)
We found that people with amyloid plaques who had more severe sleep apneas also were more likely to have lower volumes in the medial temporal lobe area of the brain, including the hippocampus, which plays a role in memory and Alzheimer's disease," a coauthor said in a statement. (mdnewsline.com)
METHODS: During a 5.7-year period, 43 patients underwent resection of temporal lobe AVMs, 10 of which were located in the medial temporal lobe (amygdala and uncus [Region A] or hippocampus, parahippocampus, and fusiform gyrus [Region B]). AVMs were evenly distributed by region and by hemispheric dominance and included two Spetzler-Martin Grade IV lesions. (barrowneuro.org)
Furthermore, the hippocampus and the extended medial temporal lobe (MTL) are rich in estradiol and progesterone receptors, suggesting their significance in hormonal modulation. (debuglies.com)
The study reports when rumination occurs, coupling between the core and medial temporal lobe subsystems of the default mode network becomes elevated, while coupling between the core and dorsomedial prefrontal cortex decreases. (neurosciencenews.com)
Prefrontal selection and medial temporal lobe reactivation in retrieval of short-term verbal information. (ox.ac.uk)
The signal was found in a network of entorhinal/subicular, posterior and medial parietal, lateral temporal and medial prefrontal areas. (nature.com)
Bilateral5
Axial, T2-weighted magnetic resonance imaging (MRI) scan reveals atrophic changes within bilateral temporal lobes with prominence of the sylvian fissures. (medscape.com)
Based on previous findings, we expected that these tasks would result in activation of bilateral temporal and inferior frontal cortices. (ajnr.org)
Both temporal lobes herniate through the tentorial notch because of bilateral mass effects or diffuse brain edema. (msdmanuals.com)
Síndrome neuroconductual asociado con disfunción bilateral del área medial del lóbulo temporal. (bvsalud.org)
A neurobehavioral syndrome associated with bilateral medial temporal lobe dysfunction. (bvsalud.org)
Parietal4
The medial temporal lobe and medial parietal cortex work in tandem to assist in the recognition of faces and places. (neurosciencenews.com)
Some researchers claim it is activated by using our Temporal-Parietal cortices. (selfgrowth.com)
The temporal lobes are located on the sides of the brain under the parietal lobes and behind the frontal lobes at about the level of the ears. (brainline.org)
In the elderly control volunteers, activation during memory encoding was observed in medial and lateral temporal lobe structures (fusiform, parietal and occipital parts, and hippocampal formation) and in the frontal cortex, as reported previously in studies of young control volunteers. (ajnr.org)
Amygdala1
White matter hyperintensity volume and biomarkers for medial temporal lobe neurodegeneration (eg, amygdala volume, hippocampal volume, and parahippocampal-entorhinal cortical thickness) on structural MRI and entorhinal white matter fractional anisotropy on diffusion tensor MRI were also measured. (elsevierpure.com)
Cortical2
Medial temporal lobe cortical changes in response to exercise interventions in people with early psychosis. (greenmedinfo.com)
Dissociating distinct cortical networks associated with subregions of the human medial temporal lobe using precision neuroimaging. (mpg.de)
Structures2
Investigations of memory in rats and nonhuman primates have demonstrated functional specialization within the medial temporal lobe (MTL), a set of heavily interconnected structures including the hippocampal formation and underlying entorhinal, perirhinal, and parahippocampal cortices. (jneurosci.org)
Much neuropsychological and neuroimaging research has been focused on the contributions of different medial temporal lobe (MTL) structures to recognition memory. (uwo.ca)
Frontal lobes1
Located behind the forehead, the frontal lobes are the largest lobes of the brain. (brainline.org)
Episodic memory1
Claire André, Ph.D., from Normandie University in France, and colleagues examined the impact of amyloid positivity on the associations between SDB severity, medial temporal lobe subregions, and episodic memory performance in cognitively unimpaired older adults using data from the Age-Well randomized controlled trial. (mdnewsline.com)
Atrophy6
We conducted an interobserver study to assess agreement on visual rating of medial temporal lobeatrophy on coronal T1-weighted MRI. (nih.gov)
After dichotomizing medial temporal lobeatrophy into present or absent, a post hoc analysis revealed higher complete agreement (70%), with kappa values of 0.59 (95% CI = 0.51-0.67) and 0.62 (95% CI = 0.48-0.075), for the two techniques (all four raters). (nih.gov)
From this study we conclude that visual rating of medial temporal lobeatrophy on MRI in the coronal plane yields fair to good agreement among observers. (nih.gov)
We recommend this type of visual rating for use in clinical settings when a quick judgement on the presence of medial temporal lobeatrophy is needed. (nih.gov)
Sleep-disordered breathing (SDB) is associated with medial temporal lobeatrophy in cognitively unimpaired amyloid-positive older adults, according to a study published online May 31 in Neurology . (mdnewsline.com)
Baseline plasma (p-tau 181 and neurofilament light chain) and MRI-based structural medial temporal lobe subregional measurements and their association with longitudinal measures of atrophy and cognitive decline were tested using stepwise linear mixed effect modeling in CN and MCI, as well as separately in the Aβ+/Aβ− subgroups. (lu.se)
Entorhinal cortex1
Therefore, we examined the degree of collateralization of NI projections to the MS and the medial temporal lobe (MTL), comprising medial and lateral entorhinal cortex (MEnt, LEnt) and dentate gyrus (DG), and the ability of the MS to drive entorhinal theta in the adult rat. (listlabs.com)
Patients3
He also noticed that in the more than 25 patients he examined with aphasia , they all had lesions to the left frontal lobe but there was no damage to the right hemisphere of the brain. (wikipedia.org)
Karl Wernicke subsequently reported patients with damage further back in the temporal lobe who could speak but were unable to understand what was said to them, providing evidence for two potentially interconnected language centres. (wikipedia.org)
The purpose was to determine the feasibility of functional MR imaging during a learning task in healthy elderly volunteers and in patients with Alzheimer's disease and to test our hypothesis that brain activation is decreased in the medial temporal lobe (MTL) memory system in patients with Alzheimer's disease compared with control volunteers. (ajnr.org)
Structural1
Conclusions and Relevance: Abrupt hormonal changes associated with BSO in premenopausal women may lead to medial temporal lobe structural abnormalities later in life. (elsevierpure.com)
Volumes2
Higher sleep apnea severity related to lower medial temporal lobe subregion volumes in amyloid-positive, but not amyloid-negative, individuals. (mdnewsline.com)
The researchers found interactions for the apnea-hypopnea index with entorhinal, whole hippocampal, subiculum, Cornu Ammonis (CA)1, and dentate gyrus volumes, with higher sleep apnea severity related to lower medial temporal lobe subregion volumes in amyloid-positive, but not amyloid-negative, individuals. (mdnewsline.com)
Hippocampal formation1
Mnemonic construction and representation of temporal structure in the hippocampal formation. (mpg.de)
Processes2
It is well-established that the medial temporal lobe (MTL) is crucial to both processes, but the MTL is not a single homogeneous region. (utexas.edu)
AKT1 controls important processes in medial temporal lobe (MTL) development and plasticity, but the impact of human genetic variation in AKT1 on these processes is not known in healthy or disease states. (johnshopkins.edu)
Memory3
Current theories of medial temporal lobe (MTL) memory organization are in conflict regarding two major issues. (jneurosci.org)
The time-limited role of the medial temporal lobe (MTL) in human long-term memory is well known. (mit.edu)
We also present key characteristics of the so-called 'concept cells', neurons in the human medial temporal lobe with selective and invariant responses that represent the meaning of the stimulus, and discuss their proposed role in declarative memory. (le.ac.uk)
Representations1
2020. Representations of common event structure in medial temporal lobe and frontoparietal cortex support efficient inference. (github.com)
Verbal1
Parsing for noun plurals appears to be a time-costly process, which we attribute to the ambiguity of -en,a suffix that is predominantly used as a verbal ending. (mpi.nl)
Objective2
Objective: To investigate medial temporal lobe structure, white matter lesion load, and β-amyloid deposition in women who underwent BSO before age 50 years and before reaching natural menopause. (elsevierpure.com)
OBJECTIVE: Arteriovenous malformations (AVMs) of the medial temporal lobe are usually resected through subtemporal-transcortical approaches that provide a trajectory that is perpendicular to the plane of the AVM. (barrowneuro.org)
Researchers1
Researchers implicate the medial temporal lobe subsystem in guiding our prosocial behaviors. (neurosciencenews.com)
Reveals1
Axial diffusion-weighted image reveals restricted diffusion in left medial temporal lobe consistent with herpes encephalitis. (medscape.com)
Role2
Previous studies have suggested that the perirhinal cortex, a part of the medial temporal lobe, plays an important role in reward-related information processing. (jneurosci.org)
However, data are lacking on the association of BSO before menopause with imaging biomarkers that indicate medial temporal lobe neurodegeneration and Alzheimer disease pathophysiology. (elsevierpure.com)
Visual1
We investigated the roles of storage and parsing in the visual domain for the productive Dutch plural suffix -en.Two experiments are reported that show that storage occurs for high-frequency noun plurals. (mpi.nl)
Women1
Results indicated a positive correlation between the executive control network and cognitive complaint score, weaker negative functional connectivity within the frontal cortex, and stronger positive connectivity within the right middle temporal gyrus in postmenopausal women who report more cognitive complaints. (frontiersin.org)