• cytoskeleton
  • In the context of cell adhesion to the extracellular matrix, the forces that are generated within the actin cytoskeleton and transmitted through integrin-based focal adhesions are essential for the cellular response to environmental clues, such as the spatial distribution of adhesive ligands or matrix stiffness. (uni-hd.de)
  • Previous studies have described individual cellular elements with potential mechanosignaling properties, including ion channels, 6 integrins, 7 the glycocalyx, 8 cilia, 9 platelet endothelial cell adhesion molecule-1 (PECAM-1), 10 various receptors for humoral compounds, 11 the cytoskeleton, 12 and the plasma membrane, including lipid raft and caveolar subdomains. (ahajournals.org)
  • Thus, the cytoskeleton plays a key role in cellular responses to oxidative stress and the onset of oxidative stress-induced neurodegeneration. (mdpi.com)
  • events
  • The essential feature of this concept is its ability to categorize cellular events in terms of either type of default reaction, predict the details of each, and potentially exploit them clinically. (physiology.org)