Cell DeathCell SurvivalApoptosisSurvival RateCause of DeathSignal TransductionCaspasesDisease-Free SurvivalCell Line, TumorSurvival AnalysisSurvivalDeathCaspase 3Time FactorsProto-Oncogene Proteins c-bcl-2Cells, CulturedGraft SurvivalAutophagyNecrosisCell LineMitochondriaIn Situ Nick-End LabelingCell ProliferationDNA FragmentationEnzyme ActivationProto-Oncogene ProteinsTreatment OutcomeAntineoplastic Agentsbcl-X Proteinbcl-2-Associated X ProteinBlotting, WesternApoptosis Regulatory ProteinsReactive Oxygen SpeciesMice, Inbred C57BLPhosphorylationRNA, Small InterferingCaspase InhibitorsNeuronsProto-Oncogene Proteins c-aktMice, KnockoutTumor Cells, CulturedProtein-Serine-Threonine KinasesRetrospective StudiesMutationAntigens, CD95TransfectionTumor Suppressor Protein p53Kaplan-Meier EstimateImmunohistochemistryEnzyme Inhibitorsbcl-Associated Death ProteinModels, BiologicalDeath, Sudden, CardiacPhosphatidylinositol 3-KinasesNeoplasmsDose-Response Relationship, DrugCell DivisionFollow-Up StudiesPoly(ADP-ribose) PolymerasesDNA DamageOxidative StressCytoprotectionCell CycleRNA, MessengerRNA InterferenceMice, TransgenicReverse Transcriptase Polymerase Chain ReactionAmino Acid Chloromethyl KetonesCaspase 9Caspase 8Cytochromes cUp-RegulationGene Expression Regulation, NeoplasticBrain DeathNF-kappa BGene Expression RegulationHydrogen PeroxideBreast NeoplasmsInhibitor of Apoptosis ProteinsDown-RegulationMembrane ProteinsFas Ligand ProteinDisease Models, AnimalMolecular Sequence DataCysteine Proteinase InhibitorsCell DifferentiationNeoplasm StagingPrognosisLung NeoplasmsDNA-Binding ProteinsMembrane Potential, MitochondrialFetal DeathFlow CytometryAntineoplastic Combined Chemotherapy ProtocolsGene ExpressionTumor Necrosis Factor-alphaCell HypoxiaRisk FactorsCarrier ProteinsHeLa Cells