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  • Inhibition
  • Inhibition of glucose uptake in muscle and adipose tissue: A mechanism to conserve glucose Stimulation of fat breakdown in adipose tissue: The fatty acids released by lipolysis are used for production of energy in tissues like muscle, and the released glycerol provide another substrate for gluconeogenesis. (wikipedia.org)
  • Inhibition has shown to decrease plasma and urinary aldosterone concentrations by 70 - 80%, rapid hypokalaemia correction, moderate decrease of blood pressure, and an increase plasma renin activity in patients who are on a low-sodium diet. (wikipedia.org)
  • nucleus
  • This fast control may be an alternative mechanism used by circulating hormones and metabolites to communicate with control centers in the brain via the arcuate nucleus for fast feedback. (eneuro.org)
  • brain
  • Glucocorticoid stress responses can be initiated by physiological perturbations (representing reflexive responses) or by brain processes linking environmental cues with probable negative outcomes. (thefreelibrary.com)
  • Using transgenic mice that overexpress the 25 kDa C-terminal fragment of TDP-43, here we show that glucocorticoids, stress hormones known to increase the brain susceptibility to neurotoxic insults, increase the levels of soluble TDP-25 and exacerbate cognitive deficits, without altering full-length TDP-43 levels. (jneurosci.org)
  • either
  • these are widely utilized in general medical practice and numerous specialties either as replacement therapy in glucocorticoid deficiency or to suppress the immune system. (wikipedia.org)
  • This has been shown in transgenic mice with either increased or decreased sensitivity of T cell lineage to glucocorticoids. (wikipedia.org)
  • response
  • The medulla produces the catecholamines adrenaline and noradrenaline, which function to produce a rapid response throughout the body in stress situations. (wikipedia.org)
  • The activation of the stress system (and resulting increase in cortisol and Th2 shift) seen during an infection is believed to be a protective mechanism which prevents an over-activation of the inflammatory response. (wikipedia.org)
  • show
  • Additionally, we show that the mechanism underlying the glucocorticoid-mediated increase in TDP-25 levels is coupled to changes in the glutathione redox state. (jneurosci.org)
  • These data show that glucocorticoids potentiate the neurotoxic action of TDP-25 by increasing its levels and clearly indicate the role of cellular oxidative damage in this process. (jneurosci.org)
  • fast
  • Stress-induced, acute, or fast phenoptosis is the rapid deterioration of an organism induced by a life event such as breeding. (wikipedia.org)
  • slow
  • By understanding the mechanisms of slow phenoptosis we may be able to halt or even reverse the processes that cause our aging and eventual deaths. (wikipedia.org)