Mechanisms of drug toxicity potential idiosyncratic toxicities. Medical search. Frequent questions

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Anatomy10

Liver Hepatocytes Kidney Cells, Cultured Cell Line, Tumor Cell Line Bone Marrow Neurons Lung Tumor Cells, Cultured

Organisms12

Rats, Sprague-Dawley Rats, Inbred F344 Daphnia Mice, Inbred C57BL Bacillus thuringiensis Rats, Wistar Mice, Inbred BALB C Artemia Larva Mice, Nude Rabbits Mice, Inbred ICR

Diseases46

Drug-Related Side Effects and Adverse Reactions Drug-Induced Liver Injury Neoplasms HIV Infections Leukopenia Radiation Injuries Neutropenia Hematologic Diseases Lung Neoplasms Thrombocytopenia Nausea Neurotoxicity Syndromes Body Weight Neoplasm Metastasis Plant Poisoning Neoplasm Recurrence, Local Stomatitis Breast Neoplasms Adenocarcinoma Abnormalities, Drug-Induced Vomiting Carcinoma, Non-Small-Cell Lung Drug Eruptions Disease Models, Animal Gastrointestinal Diseases Drug Overdose Poisoning Mucositis Colorectal Neoplasms Disease Progression Exanthema Head and Neck Neoplasms Ovarian Neoplasms Prostatic Neoplasms Radiodermatitis Brain Neoplasms Male Urogenital Diseases Lymphoma, Non-Hodgkin Kidney Diseases Necrosis Melanoma Alopecia Diarrhea Kidney Neoplasms Liver Neoplasms Carcinoma, Squamous Cell

Chemicals and Drugs96

Pharmaceutical Preparations Acetaminophen Antineoplastic Agents Street Drugs Doxorubicin Cisplatin Antineoplastic Agents, Phytogenic Anti-HIV Agents Methotrexate Immunosuppressive Agents Cytochrome P-450 Enzyme System Fluorouracil Deoxycytidine Antimetabolites, Antineoplastic Paclitaxel Antidotes Camptothecin Cyclophosphamide Carboplatin Taxoids Teratogens Organoplatinum Compounds Water Pollutants, Chemical Leucovorin Etoposide Environmental Pollutants Glutathione Insecticides Vinblastine Antineoplastic Agents, Alkylating Plant Extracts Vincristine Antibiotics, Antineoplastic Antibodies, Monoclonal Prodrugs Ifosfamide Cadmium Methylmercury Compounds Dacarbazine Aluminum Cytochrome P-450 CYP2E1 Neurotoxins Dihydrouracil Dehydrogenase (NADP)Drug Carriers Bacterial Toxins Amyloid beta-Peptides Recombinant Proteins Antioxidants Antibodies, Monoclonal, Humanized Bleomycin Reactive Oxygen Species L-Lactate Dehydrogenase Topotecan Amifostine Melphalan Herbicides Immunotoxins Xenobiotics Endotoxins Cytarabine Tetrachlorodibenzodioxin Enzyme Inhibitors Liposomes Toxins, Biological Epirubicin Carmustine Drug Combinations Prednisone Organophosphorus Compounds Quinazolines Thiazoles Superoxide Dismutase Ethylene Glycols Paraquat Yttrium Radioisotopes Selenium Compounds Hazardous Substances Niacinamide Radiation-Sensitizing Agents Mitomycin Peptides Metals, Heavy Mercury Lead Neuroprotective Agents Polyethylene Glycols Carcinogens Mycotoxins Mitoxantrone Copper Phenylurea Compounds Pyridines Benzenesulfonates Amphotericin B Tegafur Guanine

Analytical, Diagnostic and Therapeutic Techniques and Equipment61

Toxicity Tests Drug Evaluation, Preclinical Toxicity Tests, Acute Treatment Outcome Drug Administration Schedule Drug Monitoring Drug Design Lethal Dose 50 Drug Therapy, Combination Antineoplastic Combined Chemotherapy Protocols Toxicity Tests, Chronic Retrospective Studies Infusions, Intravenous No-Observed-Adverse-Effect Level Maximum Tolerated Dose Administration, Oral Combined Modality Therapy Drug Evaluation Toxicity Tests, Subchronic Survival Analysis Disease-Free Survival Radiotherapy Dosage Survival Rate Animal Testing Alternatives Radiotherapy Organ Size Toxicity Tests, Subacute Dose Fractionation Body Weight Radiotherapy, Conformal Area Under Curve Neoplasm Staging Remission Induction Injections, Intravenous Salvage Therapy Radioimmunotherapy Clinical Trials, Phase I as Topic Drug Carriers Radiotherapy, Intensity-Modulated Disease Models, Animal Follow-Up Studies Drug Delivery Systems Drug Overdose Feasibility Studies Chemotherapy, Adjuvant Mutagenicity Tests Hematologic Tests Injections, Intraperitoneal Clinical Trials as Topic Metabolic Clearance Rate Chemoradiotherapy Dose-Response Relationship, Radiation Blood Cell Count Prospective Studies Carcinogenicity Tests Models, Biological Biological Assay Injections, Subcutaneous Inhibitory Concentration 50 Pilot Projects Chromatography, High Pressure Liquid

Phenomena and Processes32

Dose-Response Relationship, Drug Drug Interactions Time Factors Cell Survival Lethal Dose 50 Drug Synergism Graft Rejection No-Observed-Adverse-Effect Level Maximum Tolerated Dose Organ Size Body Weight Area Under Curve Oxidative Stress Apoptosis Tissue Distribution Cell Death Biotransformation Metabolic Detoxication, Drug Particle Size Drug Resistance, Neoplasm Mutation Molecular Structure Structure-Activity Relationship Metabolic Clearance Rate Dose-Response Relationship, Radiation Blood Cell Count Half-Life Cytoprotection Necrosis Larva Inhibitory Concentration 50 Genetic Vectors

Disciplines and Occupations5

Toxicology Pharmacogenetics Drug Design Toxicogenetics Ecotoxicology

Anthropology, Education, Sociology and Social Phenomena1

Safety-Based Drug Withdrawals

Technology, Industry, Agriculture4

Nanoparticles Metal Nanoparticles Liposomes Polyethylene Glycols

Information Science3

Survival Rate Radiotherapy, Conformal Radiotherapy, Intensity-Modulated

Health Care18

Safety-Based Drug Withdrawals Clinical Coding Treatment Outcome Retrospective Studies Radiation Injuries Survival Analysis Disease-Free Survival Survival Rate Area Under Curve Clinical Trials, Phase I as Topic Follow-Up Studies Feasibility Studies Clinical Trials as Topic Dose-Response Relationship, Radiation Prospective Studies Societies, Scientific Pilot Projects Inhalation Exposure

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Disciplines and Occupations Anthropology, Education, Sociology and Social Phenomena Technology, Industry, Agriculture Information Science Health Care

Drug-Related Side Effects and Adverse Reactions Toxicity Tests Toxicology Safety-Based Drug Withdrawals Clinical Coding Drug Evaluation, Preclinical Pharmaceutical Preparations Drug-Induced Liver Injury Toxicity Tests, Acute Dose-Response Relationship, Drug Pharmacogenetics Acetaminophen Antineoplastic Agents Treatment Outcome Drug Administration Schedule Street Drugs Drug Interactions Liver Doxorubicin Cisplatin Antineoplastic Agents, Phytogenic Anti-HIV Agents Methotrexate Hepatocytes Drug Monitoring Time Factors Neoplasms Cell Survival Kidney Drug Design Lethal Dose 50 Drug Therapy, Combination Antineoplastic Combined Chemotherapy Protocols Immunosuppressive Agents Drug Synergism Toxicity Tests, Chronic HIV Infections Cytochrome P-450 Enzyme System Graft Rejection Cells, Cultured Retrospective Studies Infusions, Intravenous No-Observed-Adverse-Effect Level Fluorouracil Maximum Tolerated Dose Administration, Oral Combined Modality Therapy Deoxycytidine Drug Evaluation Leukopenia Antimetabolites, Antineoplastic Radiation Injuries Paclitaxel Neutropenia Toxicity Tests, Subchronic Antidotes Survival Analysis Camptothecin Cyclophosphamide Disease-Free Survival Radiotherapy Dosage Carboplatin Hematologic Diseases Lung Neoplasms Taxoids Teratogens Survival Rate Organoplatinum Compounds Water Pollutants, Chemical Leucovorin Thrombocytopenia Etoposide Animal Testing Alternatives Environmental Pollutants Glutathione Rats, Sprague-Dawley Insecticides Vinblastine Radiotherapy Antineoplastic Agents, Alkylating Organ Size Nausea Toxicity Tests, Subacute Neurotoxicity Syndromes Plant Extracts Dose Fractionation Vincristine Body Weight Antibiotics, Antineoplastic Nanoparticles Radiotherapy, Conformal Antibodies, Monoclonal Area Under Curve Cell Line, Tumor Oxidative Stress Neoplasm Staging Neoplasm Metastasis Plant Poisoning Apoptosis Tissue Distribution

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