• This relationship may influence the mechanisms of spontaneous and therapeutically provoked tumor cell interactions with the coagulation system as a whole. (rmmj.org.il)
  • WHO CNS5 defines three main entities: embryonal tumor with multilayered rosettes (ETMR), CNS neuroblastoma FOXR2 -activated, and CNS tumor with BCOR internal tandem duplication. (medlink.com)
  • much of it results from body mechanisms that are poorly understood, but are different from those responsible for the altered reactivity associated with the specific nature of acquired i. (theodora.com)
  • Here, we uncovered a mechanism of progenitor cell allocation that stems from an incomplete process of epithelial delamination that allows progenitors to coordinate their movement with adjacent extra-embryonic tissues. (elifesciences.org)
  • Blue light exposure of the R91W;Nrl −/− mouse could therefore be used to study molecular events preceding edema formation in a cone-rich environment, and thus potentially help to develop treatment strategies for edema-based complications in macular degenerations. (nature.com)
  • Molecular mechanisms involving HELQ in the context of tumorigenesis were also described. (bvsalud.org)
  • The pressure screens always degrade the molecular mass, hurting efficiency of retaining fine particles during paper formation. (ncsu.edu)
  • 4 Notably, thrombotic events occurring locally in the brain often coincide with peripheral coagulopathy through mechanisms that are not fully understood. (rmmj.org.il)
  • Our results suggest that apical bulkheads are a protective mechanism of hepatocytes against impaired bile flow, highlighting the role of canalicular pressure in liver diseases. (lisym.org)
  • 2 The vasculature of the central nervous system (CNS) evolved to meet these unique demands in multiple ways, including through highly regulated perfusion, transendothelial transport mechanisms, and protective effects of the blood-brain barrier (BBB). (rmmj.org.il)
  • Their loss under these conditions leads to abnormally dilated canaliculi, resembling liver cell rosettes described in other hepatic diseases. (lisym.org)
  • COLUMBIA: Frederick Vernon Rand, 'The chloratic groups of plant diseases with special reference to pecan rosette. (google.by)
  • Finally, the regulation of vascular integrity, patency, and sustained blood supply depends on specialized mechanisms of hemostasis regulation adapted to the brain microenvironment. (rmmj.org.il)
  • As the active nuclear compartment contains high levels of RNA and RNA-binding proteins 1 , 5 , this provides a potential mechanism for the selective exclusion of inactive chromatin from the active compartment. (nature.com)
  • We find that early transcriptional patterning of key morphogenetic transcription factors drives the selective activation of downstream morphogenetic modules, such as GPCR signaling that activates apical-medial actomyosin activity to drive cell wedging at the future asymmetrically placed invagination point. (elifesciences.org)
  • Physical mechanisms that could be applied to the organization of euchromatin have been proposed. (nature.com)
  • The patterning and fate determination gene products do not directly affect morphogenetic changes, but rather instruct the expression of downstream morphogenetic effectors that drive a tissue primordium down a path of defined physical changes. (elifesciences.org)
  • All higher brain functions including the integration and processing of sensory and motor information, the memory storage and retrieval, and the regulation of emotional and drive states take place at the telencephalic level. (intechopen.com)
  • We show that accumulation of RNA induces formation of transcription pockets which displace transcriptionally inactive chromatin. (nature.com)
  • The remaining delaminated cells follow the movement of apically attached progenitors by a protrusion-dependent cell-cell contact mechanism, avoiding sequestration by the adjacent endoderm, ensuring their collective fate and allocation at the site of differentiation. (elifesciences.org)
  • One mechanism by which Myosin II might promote polarized cell remodeling is through contractile activity that creates tension orienting junctional disassembly. (wikipedia.org)
  • In the placodes of the forming tubes of the salivary glands in the Drosophila embryo, we previously identified spatially defined cell behaviors of cell wedging, tilting, and cell intercalation that are key to the initial stages of tube formation. (elifesciences.org)
  • The p53N236S (p53S) mutation has been found in the Werner syndrome mouse embryo fibroblast (MEFs) escaped from senescence, could be the driving force for cell escaping senescence. (bvsalud.org)
  • However, the precise mechanism in which asymmetrically localized protein complexes encourage directed intercalation remains disputed. (wikipedia.org)
  • Histological features of irAEs and AILD are distinct, likely underpinning their different immunological mechanisms. (bmj.com)
  • SYN: innate i.. passive i. acquired i.. relative i. a modified, not completely effective resistance that results when there is a sort of "fluctuating equilibrium" between the defense mechanisms of the host and the infective agent. (theodora.com)
  • The body chased with foliate scrolls and rosettes, interspersed with animals: antelope, lion, dog with an aardvark like animal in the mouth. (the-saleroom.com)
  • SYN: infection i.. general i. i. associated with widely diffused mechanisms that tend to protect the body as a whole, as compared with local i.. group i. (theodora.com)
  • This patterning in combination with the asymmetric geometrical setup ensures functional organ formation. (elifesciences.org)
  • Multiple individual cells intercalating mediolateral to the anterior-posterior axis drive the resulting global elongation of the embryo. (wikipedia.org)
  • Identification of the unique mechanism of water long-distance transport requires a solid basis of interfacial physics and thermodynamics. (springer.com)
  • A six-fold assembly of the trimeric computational oligomer had the lowest potential energy per monomer and was consistent with rosette CSC morphology. (osti.gov)
  • Prior to medical school she worked in Will Talbot's lab studying early pattern formation in zebrafish. (stanford.edu)
  • Specifically, Homans used a reductionist approach to explain the relationships between people through reinforcement mechanisms, whereby the behaviour of social actors is reinforced by reward and inhibited by punishments (Delamater, 2006). (ncl.ac.uk)
  • When comparing the ICI and AILD groups, centrilobular injury as well as granuloma formation were more prevalent in the former (p=0.067 and 0.002, respectively). (bmj.com)
  • This paper addresses a fundamental question in developmental biology, that is, how morphogenetic movements driving tissue folding are patterned to occur with the correct spatiotemporal dynamics. (elifesciences.org)
  • Future studies will be needed to uncover the underlying mechanisms in detail and to arrive at a coherent picture. (cell-stress.com)
  • A six-lobed membrane spanning cellulose synthesis complex (CSC) containing multiple cellulose synthase (CESA) glycosyltransferases mediates cellulose microfibril formation. (osti.gov)
  • Two well-defined pathological hallmarks of AD have been described: the formation of extracellular amyloid plaques and the development of intracellular neurofibrillary tangles (NFTs) formed by aggregated hyperphosphorylated TAU protein [ 4 ]. (biomedcentral.com)