Loading...
  • electrochemical
  • For example the products of digestion moving into the cells of the ileum, the hormones produced by glandular cells moving into the blood stream or the Na + , K + or Cl - ions involved in the electrochemical events of an action potential moving into or out of a neurone. (abpischools.org.uk)
  • inhibition
  • 14 Here we investigated, using oxidative (H 2 O 2 ) and nitrosative (ONOO − ) stress, the mechanisms by which inhibiting PARP-1 inhibition protect against EC death. (ahajournals.org)
  • Indeed, in Malpighian tubules of the yellow fever mosquito Aedes aegypti , the inhibition of oxidative phosphorylation with dinitrophenol brings transepithelial electrolyte and water secretion immediately to a halt and eliminates voltages across cell membranes and the whole epithelium ( Beyenbach, 2001 ). (biologists.org)
  • To examine the relationship between [ATP] i and electroconductive and electrogenic transport mechanisms in principal cells of the tubule, we measured the effects of metabolic inhibition on [ATP] i in one set of tubules, and the effects on membrane voltage and resistance of principal cells in another set of tubules. (biologists.org)
  • molecular
  • Therefore, understanding TPR will lead to the identification of hitherto unknown molecular and cellular circadian mechanisms. (jove.com)
  • This technique not only allows for dissecting the molecular and neural mechanisms of TPR, but also provides new insights into the fundamental mechanisms of the brain functions that integrate different environmental signals and regulate animal behaviors. (jove.com)
  • Drosophila have been used in classical conditioning experiments for over 40 years, thus greatly facilitating our understanding of memory, including the elucidation of the molecular mechanisms involved in cognitive diseases 1-7 . (jove.com)
  • Professor Jeanne Stachowiak 's lab is interested in what drives membrane traffic, the essential cellular process by which molecular cargo is transported. (utexas.edu)
  • importantly
  • Apart from systemic hormones and regional innervation, locally produced (endothelium-derived) factors and the myogenic response also importantly contribute to set arterial tone. (ahajournals.org)
  • influx
  • Analysis of the mechanism(s) of 22 Na + influx was performed in control and acid-activated (addition of 10 mmoll -1 proprionic acid) cells using a variety of Na + transport inhibitors (ouabain, phenamil, HOE-694 and bumetanide) and a V-type ATPase inhibitor (bafilomycin). (biologists.org)
  • cells
  • The stem cells of an early embryo are all very similar and all have the potential to become any other cell in the body - they are pluripotent. (abpischools.org.uk)
  • Sets of data from various experimental stimulation protocols (HEK cells) were analyzed simultaneously and fitted to Markov-chain models (M-models). (frontiersin.org)
  • In the current study we designed a set of experiments to reveal the underlying mechanism of DT cytotoxic activity against K562 cells. (mdpi.com)
  • The primary goal of this study was to isolate pharmacologically and characterize the mechanism and site of Na + uptake in isolated populations of gill epithelial cells. (biologists.org)
  • The cell membrane controls the movement of substances in and out of cells and organelles. (wikipedia.org)
  • While Robert Hooke 's discovery of cells in 1665 led to the proposal of the Cell Theory , Hooke misled the cell membrane theory that all cells contained a hard cell wall since only plant cells could be observed at the time. (wikipedia.org)
  • This theory extended to include animal cells to suggest a universal mechanism for cell protection and development. (wikipedia.org)
  • It was also inferred that cell membranes weren't vital components to all cells. (wikipedia.org)
  • A possible mechanism to produce these delays was the postulated synfire chain consisting of feed-forwardly connected populations of cells. (frontiersin.org)
  • signals
  • In the present work, we demonstrate that this mechanism can be extended to train recognizers for longer spatio-temporal input signals. (frontiersin.org)
  • hypertension
  • In hypertension, these vasomotor control mechanisms appear disturbed. (ahajournals.org)
  • Increased myogenic constriction in several forms of hypertension appears to be associated with more depolarized resting membrane potential and smooth muscle calcium levels also when studied at comparable/normotensive blood pressure levels. (ahajournals.org)
  • 7,11-15 Impaired EDHF-mediated dilation has also been reported in several forms of hypertension, but the underlying mechanisms are not clear. (ahajournals.org)
  • constriction
  • Myogenic constriction as well as EDHF-mediated dilation may share common signaling mechanisms, and both may control K Ca channel activity to set arterial tone. (ahajournals.org)
  • Furthermore, the model myogenic mechanism includes a rate-sensitive component that yields constriction and dilation kinetics similar to behaviors observed in vitro. (duke.edu)
  • dysfunction
  • Several studies have shown that inhibiting poly-ADP ribose polymerase-1 (PARP-1) attenuates organ dysfunction in settings such as postmyocardial infarction remodeling, 1 ischemia-reperfusion injury, 2 diabetic retinopathy, 3 septic shock, 4 diabetes, 3,5 and atherosclerosis. (ahajournals.org)
  • genes
  • Drosophila locomotor activity is a well known circadian behavioral output and has provided strong contributions to the discovery of many conserved mammalian circadian clock genes and mechanisms 4 . (jove.com)
  • uptake
  • The mechanism of such uptake remained mysterious until the chemiosmotic hypothesis provided the theoretical background to understand its energetic basis ( 6 ). (sciencemag.org)
  • contribute
  • The mechanisms by which hERG 1a/1b hetero-tetramers contribute to function in the heart, or what role hERG1b might play in disease are all questions to be answered. (frontiersin.org)
  • receptor
  • Further understanding of the properties influencing membrane traffic will create new opportunities to control the process and provide a set of physical tools to manipulate receptor recycling and signaling. (utexas.edu)