Mechanical force induces. Medical search. Frequent questions

Mechanically-induced reactivity is a promising means for designing self sensing and autonomous materials. (aps.org)
CENP-A, H1.5) in cellular stiffness, and the mechanically induced chromatin responses. (cancer.gov)
The ACME developed by Dr Sarah Robinson gave us the unique chance to investigate if Hibiscus striation patterns could be mechanically induced. (eurekalert.org)

The results of the current study indicate that Tr14 seems to limit exercise-induced muscle damage most likely via attenuation of both innate and adaptive immune responses. (hindawi.com)

Thereby, the increased tension per individual cross bridge and the stretching forces on sarcomeres induce microtrauma in muscle fibers [ 3 ]. (hindawi.com)
A load cell converts a force such as tension, compression, pressure, or torque into a signal (electrical, pneumatic or hydraulic pressure, or mechanical displacement indicator) that can be measured and standardized. (wikipedia.org)
Tension force stretches a strain gauge, causing it to get thinner and longer, resulting in an increase in resistance. (wikipedia.org)
This configuration enables locking tension to be applied to the webbing with up to a 3-to-1 mechanical tensioning advantage. (alpineshop.com)
For example, drawing webbing through the device with an applied force of 100 lbs can induce up to 300 lbs of tension in the secured webbing. (alpineshop.com)
This is very important when high load force has been applied to the webbing and is a significant improvement over the webbing release behavior of more conventional cam-lock devices that have a tendency to suddenly and dangerously release tension. (alpineshop.com)
Mechanical tension of biomembranes can be measured by super resolution (STED) microscopy of force-induced nanotubes. (mpg.de)
Increased mechanical tension showed to improve alveolar maturation and differentiation toward AT1. (lu.se)

Metal-insulator-semiconductor (MIS) devices with partially-recessed gate have been submitted to pulsed and constant voltage stress, with the aim of evaluating the impact of charge trapping processes on the dynamic properties of the devices and on the negative-bias threshold instabilities (NBTI) induced by negative gate bias. (mrs.org)
Mechanical instabilities of thin sheets has long been exploited in Nature to create patterns and ensure vital functions such as stimuli responsiveness. (ens-lyon.fr)

It was our objective to study the role of mechanical stimulation on fibronectin (FN) reorganization and recruitment by exposing fibroblasts to shear fluid flow and equibiaxial stretch. (nature.com)
A 1.1‐Pa shear stress induced: cell rounding, disruption of vitronectin receptors clusters and clustering of connexins 43 at cell-cell apposition points. (utc.fr)

Recent single-molecule studies revealed that mechanical stretching could induce transitions to elongated DNA structures. (sciencedaily.com)
Gradually, and in part as a result of the parallel growth in the structural understanding of the molecular components of the cell, together with the development of single molecule manipulation methods, scientists have become increasingly aware that the cell resembles more a mechanical factory in which many of the processes are performed by specialized machinery whose behavior is essentially mechanical in nature. (berkeley.edu)
Our laboratory is also working actively in the development of methods of single-molecule manipulation, including the use of SFM cantilevers, optical tweezers, and magnetic tweezers to investigate the mechanical properties of macromolecules. (berkeley.edu)

An acute bout of physical exercise depending on duration and intensity is known to induce changes of the immune response of both the innate and the adaptive immune system. (hindawi.com)
The complete integumentary organ system (IOS) regeneration and scarless wound healing mechanism, which occurs in specific species, body sites and developmental stages, clearly shows that mechanical stress signals and immune responses play important roles in determining the wound healing mode. (mdpi.com)

Purpose ATP could play an important role in skeletal muscle blood flow regulation by inducing vasodilation via purinergic P2 receptors. (researchgate.net)

The mechanical behavior of these composites depends in interesting ways on the elasticity of the matrix. (aps.org)
The effect of each is found to be significant and highly dependent on the intrinsic polymer mechanical behavior. (aps.org)
The elucidation of mechanical behavior utilizing industry practices can contribute to their resolution as well as medical reliability and safety. (hindawi.com)
The stepwise quenching-recovery cycles induced by the mechanical action is interpreted as a modulation of the PL blinking behavior. (lu.se)

As forces over a wide range are present in the DNA of cells, the researchers' findings provide new perspectives of possible force-dependent regulations of critical biological processes, such as DNA damage repair and gene transcriptions. (sciencedaily.com)
Avoiding resonance-induced damage Every mechanical device with a rotating mass has a residual imbalance that stimulates vibrations. (ebmpapst.com)
Some scientists, instead of warning the public about the many studies regarding massive brain changes induced by neuroleptics, are hypothesizing - based on fragmentary and contradictory research - that neuroleptics somehow help prevent brain damage. (mindfreedom.org)
This self-healing ability is tested by acting mechanically on MAPbI 3 polycrystalline microcrystals by an atomic force microscope tip (applying force, scratching, and cutting) while monitoring the PL. Although strain and crystal damage induce strong PL quenching, the initial balance between radiative and nonradiative processes in the microcrystals is restored within a few minutes. (lu.se)

The wire or foil in the strain gauge is arranged in a way that, when force is applied in one direction, a linear change in resistance results. (wikipedia.org)
When force is exerted on the load cell, the structure and resistance of the strain gauges changes and V o {\textstyle V_{o}} is measured. (wikipedia.org)

Dr. Glezer is a professor in the Georgia Tech School of Mechanical Engineering. (gatech.edu)
The research is conducted in the Fluid Mechanics Research Laboratory at the Woodruff School of Mechanical Engineering. (gatech.edu)

Further access to materials possessing a broader range of thermal and mechanical properties is accomplished by polymerising a variety of commercially available dithiols with the dipropiolamide monomer. (nature.com)
The combination of their superlative mechanical, thermal, and electronic properties can be envisioned for not only a wide range of applications, but also a test bed for fundamental science and research work. (springer.com)

His long-term goal is to understand how nucleosome composition can influence cell adaptation to mechanical challenges in the environment, and if disruption of such mechanisms may contribute to tumor malignancy. (cancer.gov)

The objective of this work is to examine the capacity of a mechanical stress to cause changes in cell/substratum and cell/cell interactions via the second messenger cAMP pathway (cyclic Adenosine Monophosphate). (utc.fr)
Firstly, mechanical stress generated during the eccentric exercise is considered as one mechanism [ 4 ]. (hindawi.com)
Distributions of the electrically induced normal pressure and tangential stress at the illuminated solid surface, as well as the field of volume electrostrictive forces, are calculated taking into account surface plasmon polariton (SPP) excitation. (springer.com)
Our techniques isolate different roles of threshold voltage shift, oxide trap formation and trapping, interface state generation, stress-induced leakage current (SILC), and eventual oxide breakdown. (mrs.org)
This paper reports on a setup and a method that enables the automated analysis of mechanical stress impact on MEMS devices. (vde-verlag.de)
We saw striations appear almost instantaneously when a mechanical stress was applied. (eurekalert.org)
This transition is induced by increasing the temperature (which affects DNA bending stress and packing defects) or by varying external ionic conditions (which affects DNA-DNA repulsive interactions and overall genome stress in the capsid). (lu.se)

Random fiber networks are structural elements in many biological and man-made materials and the prediction of their mechanical properties is desirable in many applications. (aps.org)
Here, we report a class of easily processable polyamides with stereocontrolled mechanical properties and high-fidelity shape memory behaviour. (nature.com)
Particularly, the ability to measure changes in mechanical properties of forensic trace material over time makes this technology in potential interesting for forensic examinations. (intechopen.com)
In collaboration with Emilios Dimitriadis (NIBIB) and Marc Ferrer (NCATS), he has utilized atomic force microscopy (AFM) to study mechanical properties in both 2D cultured cells and 3D bio-printed models. (cancer.gov)
In particular, the excellent mechanical properties of graphene make it a potentially good reinforcement ingredient in ceramic composites while their impressive electrical conductivity has roused interest in the area of multifunctional applications. (springer.com)
Their data successfully identified all the three proposed structures and fully characterised their respective thermo-mechanical properties. (sciencedaily.com)
In addition, as many recently developed DNA devices are based on thermo-mechanical properties of various DNA structural motifs, these findings may also have potential applications in designing new DNA devices for the future. (sciencedaily.com)
Interferon-induced transmembrane protein 3 blocks fusion of diverse enveloped viruses by altering mechanical properties of cell membranes. (mpg.de)
Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density. (mpg.de)
The petal striations on hibiscus flowers develop during petal growth, and Professor Beverley Glover's team , who were the first to discover the iridescence properties in flowers, suspected that they may be caused by mechanical properties as the petals expanded", said Dr Sarah Robinson in the University of Cambridge's Sainsbury Laboratory and lead of the research. (eurekalert.org)
Working with members of Professor Glover's team , Dr Robinson was able to test this model by using a robotic system, called ACME (automated confocal micro-extensometer) that she had earlier developed to measure mechanical properties in plants. (eurekalert.org)
It is these two layers with different mechanical properties that makes the buckling possible. (eurekalert.org)
In these situations, incorporation of continuous dermatotraction can expedite wound reapposition by capitalizing on the viscoelastic properties of skin to induce mechanical creep. (medscape.com)

Here we explore the theoretical influence of nanoscale spatial force distributions and fast temporal force fluctuations on the mechanochromic response of these systems. (aps.org)

Mechanical stimulation was also combined with a Rho inhibitor to probe their coupled effects on FN. (nature.com)
Mechanical stimulation coupled with chemical stimulation also revealed an increase in FN fibrils around the cell periphery. (nature.com)
These results show that mechanical stimulation directly affected FN reorganization and recruitment, despite perturbation by chemical stimulation. (nature.com)
Though most of these studies have probed these questions through chemical stimulation, mechanical stimulation has been shown to be extremely important. (nature.com)
Stem cells differentiate into bone-forming osteoblasts, and mechanical stimulation is involved in this p. (biomedcentral.com)
If the stimulation force coincides with the device's natural oscillation, this produces a state of resonance. (ebmpapst.com)

To further their research, Assoc Prof Yan and his team will study the physiological functions of the three overstretched DNA structures, and investigate the presence of any new DNA structures under other mechanical constraints. (sciencedaily.com)

Acoustic waves themselves are waves of mechanical motion: of air molecules or some other fluid medium. (wikipedia.org)
and vibration-induced fluid atomization for two-phase cooling and coating applications. (gatech.edu)
This thesis unravels the basis of fluid-structure interaction between the 2D planar space-filling SFG-generated flow and a flexible piezoelectric thin-film by means of an in-house established system, namely the piezoelectric thin-film flapping velocimetry (PTFV) that enables the SFG-generated turbulence mechanical characteristics, particularly the induced forcing to be fundamentally enlightened. (figshare.com)
While the governing equations for the fluid are linear in this regime, we show that the presence of the hair bed induces a nonlinear relationship between the forcing parameters and the system's mechanical impedance, contrasting the rigid limit. (aps.org)

The flow‐induced forces may influence the morphological and the biochemical responses of adhering cells. (utc.fr)
Contact-induced apical asymmetry drives the thigmotropic responses of Candida albicans hyphae. (exeter.ac.uk)

It is a force transducer. (wikipedia.org)
Loudspeakers consist of a transducer and mechanical moving parts. (wikipedia.org)

Biochemical processes as diverse as the elastic response of DNA, protein-induced DNA bending, chromosomal segregation, replication, transcription, translation, protein translocation across membranes, catalyzed protein and nucleic acid folding and unfolding, and even the ubiquitous processes of induced-fit molecular recognition, are all examples in which forces and torques develop in molecules as they move along their reaction coordinates. (berkeley.edu)

Acute tip re-orientation occurred only in cells where forward growth was countered by hyphal friction sufficient to generate a tip force of ∼ 8.7 μN (1.2 MPa), more than that required to penetrate host-cell membranes. (exeter.ac.uk)
The usefulness of force measurements to evaluate the elasticity of red blood cells (RBCs) in relation to the age of a bloodstain is an interesting example. (intechopen.com)
This study demonstrates the development of a gene delivery platform based on conical SiNW arrays for mechanical cell transfection, assisted by centrifugal force, for both adherent and nonadherent cells in vitro. (bsz-bw.de)
Because human mesenchymal stem cells are known to be sensitive to their mechanical environments, we investigated the mechanotransductive potential of Descemet membrane-like microtopography (DLT) to differentiate human mesenchymal stem cells into CEC-like cells. (lww.com)

The coordination number of the catalytic zinc ion in alcohol dehydrogenase has been studied by integrated ab initio quantum chemical and molecular mechanical geometry optimisations involving the whole enzyme. (lu.se)

The impedance analogy is a method of representing a mechanical system by an analogous electrical system. (wikipedia.org)
All laws of circuit analysis , such as Kirchhoff's circuit laws , that apply in the electrical domain also apply to the mechanical impedance analogy. (wikipedia.org)
The impedance analogy is one of the two main mechanical-electrical analogies used for representing mechanical systems in the electrical domain, the other being the mobility analogy . (wikipedia.org)
The impedance analogy preserves the analogy between electrical impedance and mechanical impedance whereas the mobility analogy does not. (wikipedia.org)
On the other hand, the mobility analogy preserves the topology of the mechanical system when transferred to the electrical domain whereas the impedance analogy does not. (wikipedia.org)
The impedance analogy is widely used to model the behaviour of mechanical filters . (wikipedia.org)
[5] In the impedance analogy the effort variable is force and the flow variable is velocity . (wikipedia.org)

The mechanophore reaction kinetics, as determined by ab initio steered molecular dynamics, are exponential in force. (aps.org)
Despite our growing understanding of the role of physical forces in lung development, the molecular mechanisms that regulate the transduction of mechanical stretch to alveolar differentiation remain elusive. (lu.se)

The four-coordinate structure with a water molecule bound to the zinc ion is about 20 kJ/mole less strained than the corresponding structure with a hydroxide ion, indicating that the enzyme does not speed up the reaction by forcing the zinc coordination sphere into a structure similar to the reaction intermediates. (lu.se)

The development of efficient methods to suppress or control deformation-induced surface roughening requires a deep understanding of the roughening mechanisms operative at different scales. (frontiersin.org)

Therefore, the goal of our study is to determine the electromagnetic forces exerted on the material surface allowing for interference of the incident electromagnetic field with the excited SPP. (springer.com)
The overall goal of this experimental procedure is to enable accumulation of diverse reliable statistical parameters that characterize spatial and temporal evolution of water waves under study and time-dependent wind forcing. (jove.com)
In their recent study, the researchers systematically investigated the three possible transitions induced by mechanical stretching, with methods to control DNA construct, temperature, force and salt concentration. (sciencedaily.com)
This study investigated the hepatoprotective potential of the Solanum lycopersicum in rats intoxicated with Isoniazid and Rifampicin (INH+RIF) to induce hepatotoxicity. (bvsalud.org)
In an in vitro bovine cartilage study, mechanical injury to cartilage increased the matrix metalloproteinase-induced cleavage of cartilage aggrecan. (lu.se)

However, the effects of age on muscle response and injury resulting from repetitive exposures to mechanical loading have not been studied extensively. (cdc.gov)
Our findings show that balanced ROCK-Yap/Taz signaling is essential to regulate AT1 differentiation in response to mechanical stretching of the fetal lung, which might be helpful in improving lung development and regeneration. (lu.se)
Using AFM combined with ITC, we have recently shown that restricted intra-capsid DNA mobility can be characterized by a solid-like mechanical response to nano-indentation of a DNA-filled capsid. (lu.se)

They applied a specific force to stretch immature hibiscus ( Hibiscus trionum ) petals that had not yet developed striations to see if it was possible to mechanically induce the patterns. (eurekalert.org)
By manipulating ROCK pathway, we demonstrate that stretch-induced Yap/Taz activation promotes alveolar differentiation toward AT1 phenotype via ROCK activity. (lu.se)

Before an electrical analogy can be developed for a mechanical system, it must first be described as an abstract mechanical network . (wikipedia.org)
abstract = "The photoluminescence (PL) of metal halide perovskites can recover after light or current-induced degradation. (lu.se)

We tested the specific hypothesis that young animals can adapt to repetitive mechanical loading of potentially injurious SSCs while older animals will not be able to adapt. (cdc.gov)

Finally, understanding the nanoscale colloidal forces and geometric frustration between these new building blocks will enable the design of nanostructured solids made by out-of-equilibrium assembly. (ens-lyon.fr)

Mechanical cues can stimulate the expression of an osteogenic phenotype, enhance matrix and. (biomedcentral.com)

They also offer insight into the evolutionary forces and environmental factors driving the diversity of form and function of these highly complex structures. (grc.org)
The significance of the mechanical pressure of light in creation of laser-induced periodic surface structures (LIPSSs) is investigated. (springer.com)
The calculated fields of the electromagnetic forces are found to agree well with the experimental ripple structures. (springer.com)
Various applications of the laser-induced periodic surface structures (LIPSSs) have been proposed. (springer.com)
A team of researchers led by Associate Professor Yan Jie from the Department of Physics at the National University of Singapore (NUS) Faculty of Science has identified three new distinct overstretched deoxyribonucleic acid (DNA) structures caused by mechanical stretching. (sciencedaily.com)

Spherical magnet spins due to a rolling force and defies gravity! (overunity.com)
Faraday hypothesized that somehow the magnet "induced" the current in the wire, and named the phenomenon "induction. (visionlearning.com)

The analysis of these results, in terms of a statistical-mechanical model that incorporates polymer flexibility as well as the excluded volume of the protein, shows that the dramatic enhancement of bovine pancreatic trypsin inhibitor self-association can be quantitatively rationalized in terms of hard repulsive interactions. (lu.se)

Understanding the fundamental characteristics of square fractal grid (SFG)-generated turbulence and its interplay with fractal geometrical parameters are indispensable for effective utilisation of SFGs to improve turbulent mixing, forced convective heat transfer and fluidic energy harvesting capacity. (figshare.com)

These investigations should help provide a better understanding of the early biochemical events triggered by mechanical forces. (utc.fr)

Mechanical Aspects of Deformation-Induced Surface Roughening in the Presence of Inclusions in a Subsurface Layer. (frontiersin.org)
This graviton-induced decoherence is compared to standard sources of decoherence in the presence of the Earth MSW effect. (lu.se)

Reducing musculoskeletal disorders , which are soft-tissue injuries caused by sudden or sustained exposure to repetitive motion, force, vibration, and awkward positions. (cdc.gov)

When force is exerted on the load cell, the spring element is slightly deformed, and unless overloaded, always returns to its original shape. (wikipedia.org)
As a PhD student with Alex Brand in the Aberdeen Fungal Group and a post-doc with Rob Arkowitz in Nice, I generated novel techniques via cross-faculty approaches to define previously-impossible-to-measure live-cell applied-forces and fluorescent protein dynamics within invasive pathogenic fungi against tissue-soft substrates. (exeter.ac.uk)

Mechanical analogies are required for the three passive electrical elements, namely, resistance , inductance and capacitance . (wikipedia.org)
The mechanical analogy of electrical resistance is the loss of energy of a moving system through such processes as friction . (wikipedia.org)
A mechanical component analogous to a resistor is a shock absorber and the property analogous to resistance is damping . (wikipedia.org)

It is clear that susceptibility to contraction-induced injury increases with age in both humans [I], and animals [2]. (cdc.gov)

Fans for AHUs - solutions to avoid resonance-induced vibrations' Speaker: Uwe Sigloch, Head of Product & Market Management at ebm-papst Mulfingen Date: Monday, March 11, 2019, 15:30 Venue: Air-Conditioning Forum in Hall 8.0 A19 / A31 Residential ventilation helps to improve the quality of ambient air Special fans that control both air intake and exhaust are needed for residential ventilation in both new and renovated buildings. (ebmpapst.com)
The system comprises a 6-inch compatible automated wafer stage with electrical probing capability combined with an impact control unit for the appl ication of well defined forces to the MEMS device. (vde-verlag.de)
The impact control unit itself consists of an xyz stage for the precise positioning of an impact object that is moved against a target in a force-controlled mode. (vde-verlag.de)
However, we could not induce striations in other parts of the petals, suggesting that the ability to form striations is under genetic control," said Dr Robinson. (eurekalert.org)

Crucially, a marginal point separates the rigid or jammed state from the mechanical vacuum (freely flowing) state - at their marginal points, soft materials are neither solid nor liquid. (aps.org)

Hydraulic pumps are the mechanical devices that convert mechanical power into hydraulic energy or hydrostatic energy. (fortunebusinessinsights.com)
By this, it creates a vacuum at the pump inlet, which forces liquid from the reservoir into the pump's inlet line, and thereby mechanical action of pump delivers this liquid to the pump outlet and forces it into the hydraulic system. (fortunebusinessinsights.com)

The mathematical behaviour of the simulated electrical system is identical to the mathematical behaviour of the represented mechanical system. (wikipedia.org)

In forensic examinations where topographic characterization is important like in fingermark, textile and document forgery examinations, the atomic force microscopy (AFM) imaging technique can be of value. (intechopen.com)
We use atomic force microscopy (AFM) nano-indentation method to measure DNA mobility in the capsid. (lu.se)

What these analogies are is determined by what mechanical property is chosen to represent "effort", the analogy of voltage , and the property chosen to represent "flow", the analogy of current . (wikipedia.org)
Such pumps generate strong flow with enough power to overcome the pressure induced by load at the pump outlet. (fortunebusinessinsights.com)
The induced flow and mixing of particles into the alloy are investigated using numerical modelling (left) and laboratory-scale experiments (right - top view of metal flow in a crucible). (lu.lv)

Mechanically sensitive chemical groups termed mechanophores can be covalently linked into polymers in order to trigger specific chemical reactions upon mechanical loading. (aps.org)
No animal shall be induced or encouraged to perform through the use of chemical, mechanical, electrical or manual devices which may cause physical injury or suffering. (peta.org)
The Manufacturing sector includes establishments engaged in the mechanical, physical, or chemical transformation of materials, substances, or components into new products under NAICS codes 31-33 . (cdc.gov)

Transducers are provided at the input and output of the filter to convert between the electrical and mechanical domains. (wikipedia.org)

Recently, for example, we used force-measuring optical tweezers to induce complete mechanical unfolding and refolding of individual Escherichia coli ribonuclease H (RNase H) molecules. (berkeley.edu)

This model was used to develop a system to analyze the stresses on the teeth and supporting bone structure during occlusion based on the finite element method and to examine the possibility of mechanical simulation. (hindawi.com)

This feature is similar to, and within the working load levels induced by ratchet type devices. (alpineshop.com)
General purpose cam-lock devices lack this feature and typically are limited to tensioning capabilities far less than even a 2-to-1 mechanical tensioning advantage. (alpineshop.com)

Experimental and numerical studies have shown that it is structural inhomogeneity which is responsible for free surface roughening in the absence of external forces. (frontiersin.org)

Further, dynamic loads can be induced to the device under test at frequencies of up to 1 kHz. (vde-verlag.de)

Bone is a load-bearing tissue and physical forces play key roles in the development and maintenance of its structure. (biomedcentral.com)

In civil engineering "buckling" is a dirty word with the buckling of beams and columns leading to mechanical failure - and is something that engineers want to avoid. (eurekalert.org)

The mechanical aspects of deformation-induced surface roughening inherent in microstructural inhomogeneity are studied numerically using single inclusion models. (frontiersin.org)
Being flat in the undeformed state, the material free surface roughens under deformation in the absence of external forces applied across its plane. (frontiersin.org)
Popov and Li, 2018 ), the idea of controllable deformation-induced surface roughening sounds attractive. (frontiersin.org)
By applying forces at the surface of thin objects, it is possible to create a wide variety of chiral 3D shapes such as helices, twists and rolls. (ens-lyon.fr)

Anatomy51

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