Preoperative serumCytokeratin 19 fragmentAssayGlycoproteinHepatocellular carcinomaColorectalCalcitoninTumor markerBiopsySquamous cell carcQuantificationColon cancerTumourAssaysBiomarkersProteinConcentrationsConcentrationDetectionPrognosisProteinsLiverImmunoassayThyroidRecurrenceBiochemicalClinicalLevelCancerPatientsFluidHumanTissueNuclearParametersNormalExamplesLower
Preoperative serum4
- Detection of PRL-3 protein in the preoperative serum of patients with colorectal cancer. (edu.pl)
- Univariate and multivariate analyses were performed by the logistic regression procedure to determine the relationship between pathological lymph node metastasis-positive status and clinical or radiological findings such as the maximum dimensions of consolidation and the tumour, the presence of air bronchogram, pleural indentation and the preoperative serum carcinoembryonic antigen (CEA) level. (nih.gov)
- 0.001) and preoperative serum carcinoembryonic antigen (CEA) level (p = 0.017) are independent risk factors lymph node metastasis in cN0 NSCLC. (biomedcentral.com)
- Tumor consolidation diameter and preoperative serum CEA are independent factors to predict cN0 NSCLC with tumor size ≤ 30 mm. (biomedcentral.com)
Cytokeratin 19 fragment2
- To explore the application value of tumor markers carcinoembryonic antigen and cytokeratin 19 fragment in the progression and prognosis of middle-advanced non-small cell lung cancer. (ijpsonline.com)
- Previous studies have suggested that several factors are associated with recurrence or reduced survival, such as carcinoembryonic antigen, epithelial growth factor receptor, and cytokeratin-19 fragment ( 3 , 4 ). (iiarjournals.org)
Assay2
- Carcinoembryonic antigen (CEA) assay. (cancer.gov)
- The results of non-smoker females with primary CA15-3) suspicion of symptomatic serum CEA assay can reflect progno- breast cancer, without signs or symp- metastasis. (who.int)
Glycoprotein4
- Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion . (wikidoc.org)
- Carcinoembryonic antigen (CEA) is glycoprotein associated with various functions of endothelial cells, including adhesion, proliferation, and migration. (degruyter.com)
- SCC-Ag is a subfraction of the tumor-associated antigen TA-4, and it is a 45-kDa glycoprotein. (koreamed.org)
- Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. (lookformedical.com)
Hepatocellular carcinoma1
- They reappear in the adult serum during certain pathologic states, primarily hepatocellular carcinoma. (curehunter.com)
Colorectal2
- [3] It was found that serum from individuals with colorectal, gastric, pancreatic, lung and breast carcinomas had higher levels of CEA than healthy individuals. (wikidoc.org)
- A total of 2226 deter- or regression status in breast cancer cological (lung, colorectal, pancreas minations of serum CEA and CA15-3 patients [5-8]. (who.int)
Calcitonin3
- While the increased serum concentration of calcitonin is not harmful, it is useful as a marker which can be tested in blood. (wikipedia.org)
- In general, measurement of serum CEA is less sensitive than serum calcitonin for detecting the presence of a tumor, but has less minute to minute variability and is therefore useful as an indicator of tumor mass. (wikipedia.org)
- [ 5 , 6 ] but the ATA guidelines make no recommendation on the routine measurement of serum calcitonin because of insufficient evidence. (medscape.com)
Tumor marker4
- A second marker, carcinoembryonic antigen (CEA), also produced by medullary thyroid carcinoma, is released into the blood and it is useful as a serum or blood tumor marker. (wikipedia.org)
- Whether measurement of acetylcholine levels in the blood or urine could be a tumor marker of HNPGLs should be investigated soon. (bvsalud.org)
- CEA measurement is mainly used as a tumor marker to identify recurrences after surgical resection. (wikidoc.org)
- Although a serum tumor marker test is not included in the routine post-treatment surveillance recommended by the SGO, tumor markers such as squamous cell carcinoma antigen (SCC-Ag) and carcinoembryonic antigen are evaluated and they are used to detect recurrent disease [ 4 ]. (koreamed.org)
Biopsy1
- All the guidelines advocate ultrasound evaluation of thyroid nodules along with measurement of serum thyroid-stimulating hormone (TSH) levels to determine whether a fine needle aspiration biopsy (FNAB) is indicated. (medscape.com)
Squamous cell carc4
- Both carcinoembryonic antigen and cytokeratin 19 can be used in the diagnosis of squamous cell carcinoma and adenocarcinoma. (ijpsonline.com)
- When cytokeratin 19 was positive and carcinoembryonic antigen was negative, the proportion of squamous cell carcinoma was significantly higher than that of adenocarcinoma. (ijpsonline.com)
- Serum SCC-Ag test was helpful in detecting recurrent cervical squamous cell carcinoma during post-treatment surveillance, and the optimal cutoff value was ≥2 ng/mL. (koreamed.org)
- Increased serum SCC-Ag levels are observed in squamous cell carcinoma of the esophagus, lung, head and neck, and cervix, but increased levels may also be found in benign diseases such as skin disorders [ 5 ], pelvic inflammatory disease, cystitis, and renal failure [ 6 7 ]. (koreamed.org)
Quantification1
- The simultaneous quantification of CEA, NSE, and PSA at different concentrations in the same serum test demonstrated real multiplexing Tb-to-QD FRET immunoassays as well as the potential of the technology for translation into scientific diagnostics. (remithibert.net)
Colon cancer1
Tumour3
- However, the impact of GGO on the T factor in the TNM staging system remains unclear and the maximum tumour dimension is also an uncertain measurement for assessing the prognosis of early lung cancer with a mixture of consolidation and GGO. (nih.gov)
- ABSTRACT The value of serum tumour markers in the prognosis of patients with breast cancer is controversial. (who.int)
- This prospective study in Yazd, Islamic Republic of Iran, assessed the value of the tumour markers carcinoembryonic antigen (CEA) and cancer antigen (CA) 15-3 in 159 patients with primary breast cancer. (who.int)
Assays2
- Antidrug antibody assays performed on serum from the first 4 cohorts were all negative. (snmjournals.org)
- In addition to the identification of new biomarkers, the platforms and assays required to accurately and reproducibly measure biomarkers play a key role in ensuring consistency of measurement both within and between patients. (biomedcentral.com)
Biomarkers3
- Compared with the clinical monitoring techniques of Computed tomography (CT), Positron emission tomography computed tomography (PET-CT), and specific biomarkers, the detection of serum tumor markers was more simple, rapid and less invasive and has important clinical application value[ 6 - 9 ]. (ijpsonline.com)
- In this review we discuss the current knowledge in the area of peripheral immune-based biomarkers, drawing information from the results of recent clinical studies of a number of different immunotherapy modalities in the treatment of cancer, including checkpoint inhibitors, bispecific antibodies, chimeric antigen receptor T cells, and anti-cancer vaccines. (biomedcentral.com)
- Table 1 lists example technologies that may be employed for the measurement of circulating biomarkers. (biomedcentral.com)
Protein1
- According Light et al's criteria for pleural fluid, an exudate is considered if one of the following parameters are met: the total protein fluid-to-serum ratio is higher than 0.5, the LDH fluid-to-serum ratio is more than 0.6, or the LDH fluid level exceeds two thirds of upper limit of normal serum level. (medscape.com)
Concentrations3
- The serum concentrations of chemokine CXCL12 and its specific receptor CXCR4 in patients with esophageal cancer. (edu.pl)
- To the 100 L alternative of TbCAB/QDCAB, 50 L of differing concentrations of CEA, NSE, or PSA dissolved in serum had been added. (remithibert.net)
- However, previous studies used various cutoff values of serum SCC-Ag, ranging from 1.5 to 3.0 ng/mL, which was determined to correspond to the 95th, 98th, and 99th percentiles, or 2 times the 95th percentile of serum concentrations measured in a population of healthy women [ 6 8 10 11 12 13 14 15 16 17 18 ]. (koreamed.org)
Concentration1
- Maximum serum concentration of the radiolabeled antibody was 22.9% at 24 h (decay-corrected to injection time) and 500 Bq/mL (decay-corrected to collection time). (snmjournals.org)
Detection1
- Simple control rules are preferred over multirule combinations, along with the lowest number of control measurements (N) that will provide the optimal error detection [ 2 ]. (westgard.com)
Prognosis3
- Serum carcinoembryonic antigen and cytokeratin 19 were abnormally highly expressed in non-Small cell lung cancer patients, which are useful for clinical diagnosing, treatment planning, efficacy monitoring, and prognosis evaluation. (ijpsonline.com)
- Many studies showed that the carcinoem-bryonic antigen (CEA) and human cytokeratin fragment antigen 21-1 (CYFRA21-1) has a high value in predicting tumor recurrence and judging the prognosis of patients[ 2 , 3 ]. (ijpsonline.com)
- Circulating tumor cells also demonstrate prognostic value as liquid biopsies in certain tumor types such as breast and prostate, with measurement of nuclear proteins such as prostate cancer androgen receptor splice variant-7, providing additional supportive information for prognosis and therapy selection [ 6 ]. (biomedcentral.com)
Proteins1
- The first alpha-globulins to appear in mammalian sera during development of the embryo and the dominant serum proteins in early embryonic life. (curehunter.com)
Liver1
- Imaging studies in- was one of the first serum-based tu- The study sample was women with cluding chest X-rays, liver ultrasonog- mour markers to be characterized, primary breast cancer attending a pri- raphy and bone scans were performed and its utility has been assessed in vate clinic in Yazd, Islamic Republic if there was clinical or laboratory a variety of malignancies including of Iran. (who.int)
Immunoassay2
- relevant focus range and may end up being quantified in 50 L serum examples on the BRAHMS KRYPTOR Small PLUS scientific immunoassay dish audience. (remithibert.net)
- The levels of serum tumor markers were detected by electrochemiluminescence immunoassay. (ijpsonline.com)
Thyroid2
- A routine measurement of serum thyroglobulin (Tg) for the initial evaluation of thyroid nodules is not recommended because Tg levels are elevated in most benign thyroid conditions. (medscape.com)
- Unexplained increase of serum carcinoembryonic antigen: don't forget the thyroid! (degruyter.com)
Recurrence2
- To utilize serum SCC-Ag testing at follow-up, it is required to determine the ideal threshold value for diagnosing recurrence. (koreamed.org)
- Імунодіагностика пухлин Tumor-associated antigens (TAAs) can help diagnose various tumors and sometimes determine the response to therapy or recurrence. (msdmanuals.com)
Biochemical1
- Throughout follow-up, periodic CEA measurements remained unchanged without any other clinical symptoms or biochemical abnormalities. (degruyter.com)
Clinical2
- When faced with elevated CEA measurements, clinicians and clinical pathologists must recognize its ambivalence and thoroughly exclude any important pathology and interferences as well. (degruyter.com)
- The present case illustrates potential clinical challenges in using serum tumor markers, namely CEA, to monitor cancer patients. (degruyter.com)
Level3
- Several studies have We excluded patients who had other In the present study CEA and CA15-3 shown that changes in the CEA serum disorders that could affect the serum levels were measured from patients' level might be linked to progression level of CEA or CA15-3, whether on- serum sample. (who.int)
- Get a measurement of your CEA level before treatment to compare with CEA levels after treatment. (medlineplus.gov)
- The researchers recommend active imaging studies, when serum SCC-Ag level ≥2 ng/mL during post-treatment surveillance. (koreamed.org)
Patients2
- A total of 1,550 serum SCC-Ag tests performed during post-treatment surveillance of the 158 patients were included in this retrospective study. (koreamed.org)
- Nursing based on oxygen administration decreased the value of renal function indexes, serum inflammatory factors, and tumor markers in renal cell carcinoma patients. (biomedcentral.com)
Fluid3
- Levels of cytokeratin 19 fragments (CYFRA 21-1) and carcinoembryonic antigen (CEA) from serum and cytological fluid were measured. (elsevierpure.com)
- CONCLUSIONS: Cytological fluid measurements of CYFRA 21-1 can improve the diagnostic performance of CT-guided NAB for GGO pulmonary lesions. (elsevierpure.com)
- They may also be elevated in the amniotic fluid and maternal serum during pregnancy in ANENCEPHALY. (curehunter.com)
Human1
- Demonstration of tumor-specific antigens in human colonic carcinomata by immunological tolerance and absorption techniques. (wikidoc.org)
Tissue1
- After preparation the tissue was blocked with normal serum for 20 min at RT. (progen.com)
Nuclear1
- Dose rate measurements performed at 1 m from the patient registered less than 5μSv/h (using portable detectors) in the latest cohort, significantly less than what is normally observed using nuclear medicine imaging agents. (snmjournals.org)
Parameters1
- BIO Scan gives a full health overview of over 250 parameters through the bioelectronics measurement of the weak magnetic field of our body cells. (trambellir.com)
Normal1
- Hammarstrom S. The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. (wikidoc.org)
Examples2
- All examples had been ready in triplicate aside from the antigen-free examples, which were ready 10 situations and measured three times. (remithibert.net)
- mo /mrow /mrow /mathematics (3) where SD corresponds to the typical deviation from the antigen-free examples (30 measurements), as well as the slope was driven in the linearly increasing area of the FRET immunoassays calibration curve. (remithibert.net)
Lower1
- 5 ] The location of a rectal tumor is usually indicated by the distance between the anal verge, dentate line, or anorectal ring and the lower edge of the tumor, with measurements differing depending on the use of a rigid or flexible endoscope or digital examination. (cancer.gov)