• In view of the major contribution of intrapartum risk factors and prematurity to subsequent neurological morbidity and mortality, studies are needed that address the underlying mechanisms of brain injury that occur in utero to the immature and near-term fetal CNS. (jneurosci.org)
  • The heart is the embryo's first functioning organ, with the first heartbeats occurring approximately day 22-23 after fertilization (the sixth week of gestation in pregnancy), followed by active fetal blood circulation by the end of the sixth week. (cmda.org)
  • Antenatal glucocorticoids accelerate fetal lung maturation and reduce mortality in preterm babies but can trigger adverse effects on the cardiovascular system. (researchgate.net)
  • Fetal growth and maturation occur along a continuum throughout pregnancy. (cdc.gov)
  • Galvão A, Segers I, Smitz J, Tournaye H, De Vos M. In vitro maturation (IVM) of oocytes in patients with resistant ovary syndrome and in patients with repeated deficient oocyte maturation. (springer.com)
  • It seems that again in the 2nd IVF I also had an oocyte maturation problem. (sharedjourney.com)
  • In 1935, Pincus & Enzmann did the first experiment on immature rabbit oocyte, showing in vitro spontaneous maturation and fertilization. (wikipedia.org)
  • During a subsequent phase of maturation in the first few postnatal weeks, immature astrocytes exit the cell cycle and aquire a fully mature phenotype 1 . (nature.com)
  • In contrast, little is known of the mechanisms controlling the later step of maturation of immature postnatal astrocytes into fully mature adult astrocytes. (nature.com)
  • A final molt to the sexually immature adult stage occurs approximately 2 months (50 to 70 days) after infection. (capcvet.org)
  • Removal, via CELL DEATH, of immature lymphocytes that interact with antigens during maturation. (bvsalud.org)
  • And both systems experience maturation of their reproductive organs, which become functional during puberty as a result of the gonads secreting sex hormones. (wikibooks.org)
  • Adolescence (from Latin adolescere 'to mature') is a transitional stage of physical and psychological development that generally occurs during the period from puberty to adulthood (typically corresponding to the age of majority ). (wikipedia.org)
  • Puberty is a period of several years in which rapid physical growth and psychological changes occur, culminating in sexual maturity. (wikipedia.org)
  • Puberty occurs through a long process and begins with a surge in hormone production, which in turn causes a number of physical changes. (wikipedia.org)
  • Sexual and other physical maturation that happens during puberty is due to hormonal changes. (chkd.org)
  • In boys, puberty usually occurs between the ages of 10 and 14 years. (msdmanuals.com)
  • In vitro maturation (IVM) is the technique of letting the contents of ovarian follicles and the oocytes inside mature in vitro. (wikipedia.org)
  • Through in vitro maturation, folliculogenesis and latter parts of oogenesis are being mimicked outside of the ovaries- trying to recreate the conditions for these processes. (wikipedia.org)
  • We report the pregnancy and live birth achieved after in vitro maturation (IVM) of oocytes and PGT-A in a 23-year-old patient suffering from ovarian gonadotropin resistance. (springer.com)
  • Investigating astrocyte maturation in a cell culture model revealed that in vitro-differentiated astrocytes lack expression of many mature astrocyte-specific genes, including genes for the transcription factors Rorb, Dbx2, Lhx2 and Fezf2. (nature.com)
  • To gain insights into the mechanisms driving astrocyte maturation, we have characterised acutely isolated murine astrocytes at both postnatal and adult stages, as well as in vitro differentiated astrocytes. (nature.com)
  • The correction of transverse demonstrating its efficacy, the understanding of the maturation maxillary atresia has long been a topic of discussion in the and fusion processes of the midpalatal suture (MPS) are literature. (bvsalud.org)
  • Neurogenesis occurs in the embryonic stage and astrogliogenesis in the postnatal stage. (bartleby.com)
  • Postnatal maturation is associated with major changes in astrocyte biology. (nature.com)
  • The involvement of microRNAs, transcribed from DNA, occurs around birth, and marks a key step in postnatal development. (sciencedaily.com)
  • They can undergo fibrous maturation, appearing more whitish, or transform completely to fibromas. (aafp.org)
  • The larvae then undergo pupation until enough degree days have accumulated for emergence to occur. (ca.gov)
  • Here, we show that local network activity regulates the rate of maturation of adult-born neurons along the septotemporal axis of the hippocampus. (jneurosci.org)
  • Finally, neurons developing within a highly active environment exhibited a delayed maturation when their intrinsic electrical activity was reduced by the cell-autonomous overexpression of Kir2.1, an inward-rectifying potassium channel. (jneurosci.org)
  • Our findings reveal a novel type of activity-dependent plasticity acting on the timing of neuronal maturation and functional integration of newly generated neurons along the longitudinal axis of the adult hippocampus. (jneurosci.org)
  • Abstract During maturation of the brain, neurons and glia are formed sequentially. (bartleby.com)
  • By 1991, the first human pregnancy was recorded using IVM followed by IVF, and in 1994 the first birth using IVM oocytes from polycystic ovarian syndrome patients was recorded highlighting that PCOS patient's oocytes are capable of maturation. (wikipedia.org)
  • This leads to improved maturation and quality of the oocytes. (wikipedia.org)
  • The duration and the impact of those distinctive functional properties in the dentate gyrus network will depend on the speed of maturation of new DGCs. (jneurosci.org)
  • Astrocytes have essential functions in brain homeostasis that are established late in differentiation, but the mechanisms underlying the functional maturation of astrocytes are not well understood. (nature.com)
  • 2. Adolescence, a period of transition from childhood to adulthood, is characterized by rapid and objective physiologic changes, such as rapid growth, maturation of the reproductive system and changes in physical appearance. (who.int)
  • The adult phenotype would be adapted to the predicted environment that occurred during organism maturation. (icr.org)
  • These effects can occur both in adult and in developing animals and could also occur following inhalation or skin contact. (cdc.gov)
  • Significant psychosocial development, especially emotional, intellectual and spiritual aspects occurs through a progressive maturation process from childhood dependence to adult interdependence. (who.int)
  • Never store pesticides in containers that might appear can occur both in adult and in developing animals and could attractive to children, such as soda bottles. (cdc.gov)
  • First, phagophore formation requires cytoplasmic vesicle nucleation, which occurs when the ATG1/ULK1 complex, which is comprised of ULK1, FIP200, ATG13, and ATG101, interacts with the Class III PI3K complex. (hindawi.com)
  • I agree with the embryologist that the reason for the failed fertilization following ICSI on the first cycle was likely due to inadequate cytoplasmic maturation. (sharedjourney.com)
  • However, whether the timing of maturation of newborn DGCs can be regulated by changes that occur within a physiological range of neuronal activity remains unknown. (jneurosci.org)
  • These viticulture practices do lower the yield and remove any congestion, focusing the photosynthesis energy toward the physiological maturation of the remaining crop. (longshadows.com)
  • During pregnancy, a marked increase occurs in the vascularity and edema within the cervical stroma and an inflammatory infiltrate is present. (medscape.com)
  • Chadwick's sign is a bluish discoloration of the cervix, vagina, and vulva that can occur during pregnancy. (proprofs.com)
  • This dysregulation of transcription leads to uncontrolled growth and division (proliferation) and abnormal maturation and survival of cells, causing tumor development. (medlineplus.gov)
  • This interaction occurs at a region called the death domain that is present in both proteins. (medlineplus.gov)
  • During elongation and maturation, the phagophore encapsulates damaged proteins and cell organelles. (hindawi.com)
  • The autophagophore membrane then elongates and encloses the molecules to be degraded forming an autophagosome, which occurs in two separate conjugation reactions catalyzed by autophagy-related proteins (ATGs). (hindawi.com)
  • In other words, HIV-1 protease is responsible for maturation of the virion by cleaving proteins into their mature form. (proteopedia.org)
  • Analysis of the GnRH gene in humans shows that analogous phenomena might occur in our own species. (sciencedaily.com)
  • It was the perfect kick we needed to boost the grape maturation. (longshadows.com)
  • The septal dentate gyrus displayed higher levels of basal network activity and faster rates of newborn neuron maturation than the temporal region. (jneurosci.org)
  • One part of the brain where pattern separation occurs is called the dentate gyrus, which sits in the hippocampus-the brain region that is in charge of certain forms of learning and memory. (elifesciences.org)
  • The CBCT scans were applied to evaluate midpalatal suture maturation status and comprised stages previously classified as B (29), C (92) and D (37). (bvsalud.org)
  • Although the functions of astrocytes change profoundly during their maturation, the regulatory mechanisms underlying these changes have only begun to be examined. (nature.com)
  • The natural aging process is marked by molecular changes that occur during development, maturation, and decline. (karger.com)
  • This maturation process occurs as the virion buds from the host cell. (proteopedia.org)
  • Next, the grapes begin their maturation process. (calwineries.com)
  • The leaves then wilt and die stopping abruptly the photosynthesis and therefore the maturation process. (longshadows.com)
  • If such a relationship occurs, it may result in gingival recession, because it makes the process of cleaning difficult, leading to the retention of biofilm and culminating in a chronic inflammatory process 36 . (bvsalud.org)
  • Mastitis neonatorum or infections of the breast tissue may also occur during the newborn period. (medscape.com)
  • Here we identify extensive transcriptional changes that occur during murine astrocyte maturation in vivo that are accompanied by chromatin remodelling at enhancer elements. (nature.com)
  • Athelia (ie, absence of nipples) and amastia (ie, absence of breast tissue) may occur bilaterally or unilaterally. (medscape.com)
  • 2. Adolescence is characterized by physiologic, psychosocial, especially emotional, intellectual and spiritual development and maturation processes. (who.int)
  • The growth spurt in boys occurs during mid-adolescence between the ages of about 12 years and 16 years (most commonly about age 13½) and usually begins a year after the testes start enlarging. (msdmanuals.com)
  • The growth spurt in girls occurs in early adolescence between the ages of about 9½ years and 13½ years (most commonly about age 11½). (msdmanuals.com)
  • It typically occurs with immune suppression, such as in those with human immunodeficiency virus infection or AIDS, those who have had an organ transplant, and those taking immunosuppressants or antimicrobials. (aafp.org)
  • They often occur on the buccal gingiva between the teeth and typically bleed spontaneously without irritation. (aafp.org)
  • They showed maturation occurs in isolation from normal follicular environment. (wikipedia.org)
  • Sure that is possible but with Antagon instead of Lupron follicular dyssynchrony may occur. (sharedjourney.com)
  • These signals affect cell activities such as division, growth, and maturation. (medlineplus.gov)
  • Both low temperatur and low salinity led to slower growth and subsequently to a longer time to maturation. (int-res.com)
  • This is the first study to report on growth and maturation of H. elegans under controll laboratory conditions. (int-res.com)
  • It occurs when you inherit copies of the hemoglobin S gene from both parents. (healthline.com)
  • It occurs when you inherit the Hb C gene from one parent and the Hb S gene from the other. (healthline.com)
  • We show that astrocyte maturation is promoted by extrinsic signals that induce multiple transcription factors that act largely independently to regulate distinct gene expression modules that together promote a mature astrocytic phenotype. (nature.com)
  • The EWSR1/FLI1 fusion gene occurs in approximately 85 percent of Ewing sarcomas. (medlineplus.gov)
  • Breast disorders occurring in pediatric patients range from congenital conditions to neonatal infections and from benign disorders such as fibroadenoma in females and gynecomastia in males to breast carcinoma and rhabdomyosarcoma . (medscape.com)
  • In animal models of congenital diaphragmatic hernia (CDH), tracheal occlusion (TO) has induced maturation of both airway spaces and vascular structures. (bvsalud.org)
  • The expression and transcription of alkaline phosphatase (ALP) and BSP promote the maturation and mineralization of OB ( 5 ). (frontiersin.org)
  • Here, CDK2 is involved in the regulation of meiotic transcription, the pairing of homologous chromosomes, and the maturation of meiotic crossover sites. (lu.se)
  • Ewing sarcomas most often occur in children and young adults. (medlineplus.gov)
  • Children exposed to large amounts of methoxychlor may suffer tremors and convulsions, as would probably occur in adults. (cdc.gov)
  • The fruit may not be spaced apart and may occur in clusters of several touching each other. (krugerpark.co.za)
  • They occur in two forms: one that is attached to a B cell , and the other, a soluble form, that is unattached and found in extracellular fluids such as blood plasma . (wikipedia.org)
  • A type of CELL NUCLEUS division , occurring during maturation of the GERM CELLS . (online-medical-dictionary.org)
  • The new viral particles cannot enter the host cell without maturation which require HIV-encoded protease. (proteopedia.org)
  • This condition is generally not inherited but arises from a mutation in the body's cells that occurs after conception. (medlineplus.gov)
  • The majority of CDK2's known meiotic functions occur during prophase of the first meiotic division. (lu.se)
  • From this stage, complete maturation to Tanner stage V usually takes more than 4 years. (medscape.com)
  • Tradition dictates that harvest will occur 100 days after flowering, but this decision is ultimately the vineyard manager's. (calwineries.com)
  • An increased number of skin and soft-tissue abscesses caused by community-acquired methicillin-resistant S aureus (MRSA) have occurred in children. (medscape.com)
  • They may appear in babies as early as 4 months old, but generally occur around the 6-month mark. (healthline.com)
  • This usually occurs during late March or early April. (calwineries.com)
  • The next step in the annual life cycle of the vine is Flowering , and usually occurs in May or early June. (calwineries.com)
  • Airway and vascular maturation stimulated by tracheal occlusion do not correlate in the rabbit model of diaphragmatic hernia. (bvsalud.org)
  • Jequiez AM. Conception in the resistant ovary syndrome occurring during hormone replacement therapy: a report of two cases. (springer.com)
  • biopsied human ovarian tissue and achieved a 10% rate of maturation from unilaminar follicles into metaphase II by a multi-step culture system: 8 days of culture in a serum-free medium 8 days of culture in a serum-free medium with activin A 4 days of culture on membranes with activin A and follicle-stimulating hormone (FSH). (wikipedia.org)
  • Methoxychlor is a manufactured chemical that does not occur naturally in the environment. (cdc.gov)
  • Most people are not exposed to methoxychlor on a regular occur naturally in the environment. (cdc.gov)
  • Hand-foot syndrome occurs when sickle-shaped RBCs block blood vessels in the hands or feet. (healthline.com)
  • Breast maturation can take place over a period as short as 18 months or as long as 9 years. (medscape.com)
  • During autophagosome maturation, cargo recruitment takes place through the recruitment of ATGs and LC3, and mature autophagosome formation occurs. (hindawi.com)
  • HIV-1 Protease is a viral aspartic protease that responsible for maturation of human immunodeficiency virus (HIV) . (proteopedia.org)
  • pPNETs occur in nerve tissue and can be found in many parts of the body. (medlineplus.gov)
  • The damage to the canopy occurs when ice crystals develop within the plant tissue. (longshadows.com)
  • An extra breast (ie, polymastia) or extra nipple (ie, polythelia) occurs in approximately 1% of the population. (medscape.com)
  • 20°C, first spawning occurred on Day 16 of the experiment. (int-res.com)