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  • Arterial
  • An automated, closed-loop 1D-0D modelling framework was developed, and we demonstrate its efficacy in (1) reproducing measured multi-variate cardiovascular variables (pulse pressure, total peripheral resistance and cardiac output) and (2) providing automated estimates of variables that have not been measured (uterine arterial and venous blood flow, pulse wave velocity, pulsatility index). (springer.com)
  • It is also the first model capable of capturing wave propagation phenomena in the utero-ovarian circulation, which are important for the accurate estimation of arterial stiffness in contemporary obstetric practice. (springer.com)
  • quantitative
  • In summary, the combined protocol strategy can be readily applied for quantitative TATS network studies during physiological myocyte adaptation or disease changes, comparison of different cardiac or skeletal muscle cell types, phenotyping of transgenic models, and pharmacological or therapeutic interventions. (jove.com)
  • hierarchical model
  • We consider a Bayesian hierarchical model for the integration of gene expression levels with comparative genomic hybridization (CGH) array measurements collected on the same subjects. (rice.edu)
  • Agreement indexes are directly related to a set of covariates through a hierarchical model. (jove.com)
  • function
  • He is author or coauthor of numerous publications related to secondhand smoke and tobacco control, as well as many papers on cardiovascular function and biostatistics. (ucsf.edu)
  • However, this hypothesis remains to be tested by using definitive loss-of-function animal models. (jove.com)
  • blood
  • For example, the model is capable of simulating the heart rate, cardiac output and blood pressure in a healthy individual and under the influence of heart failure as well as treatment with beta-blockers. (paganz.org)
  • This is the first model capable of estimating volumetric blood flow to the uterus via the utero-ovarian communicating arteries. (springer.com)
  • These can be further augmented by combining uncertainty in the choice of appropriate constitutive models for the blood and the boundary conditions. (utaustinportugal.org)
  • In the case of aneurysms, the uncertainty due to the virtual model definition is comparable to that when choosing different models for the non-Newtonian behavior of blood. (utaustinportugal.org)
  • intended to simulate
  • The model is intended to simulate physiological functions and the effect of pathological conditions as well as pharmacological interventions over a time course of up to five days for the purposes of providing a teaching tool for clinical practitioners. (paganz.org)
  • Heart
  • To investigate the effects of wearing compression stockings on cardiovascular responses, the heart rate (HR), cardiac output (Q) measured by CO2 rebreathing method, and oxygen intake were measured at rest in a supine position for 40 min and standing position for 120 min. (biomedsearch.com)
  • We generate predictions using mathematical models, then test these predictions experimentally by measuring calcium and transmembrane voltage in heart cells. (mssm.edu)
  • Inherent to the groups approach is the testing of these models and devices using data obtained from our in vitro setups, from isolated (slaughterhouse) in vivo beating heart experiments, and data from animals and patients, obtained in collaboration with our academic and clinical partners. (tue.nl)
  • Circle
  • Liang, F., Fukasaku, K., Liu, H., Takagi, S.: A computational model study of the influence of the anatomy of the circle of willis on cerebral hyperperfusion following carotid artery surgery. (springer.com)
  • A model of the circle of Willis geometry was approximated as a network of tubes around cubic curves. (ahajournals.org)
  • With a network of such tubes connected by bifurcations, a complete model of the circle of Willis was constructed. (ahajournals.org)
  • experimental
  • Aim is to develop computational models, experimental techniques, and medical devices for clinical diagnosis, decision support, and intervention. (tue.nl)
  • This model requires a nephrectomy of the right kidney since ischemia can be only performed in one kidney due to the experimental setting. (jove.com)
  • uncertainty
  • Noise and flow artifacts in the medical images and clinical measurements lead to geometric models that contain some uncertainty. (utaustinportugal.org)
  • Patient-specific case studies to quantify relative bounds to this uncertainty uncovered a dire need for care in the virtual model reconstruction from medical images. (utaustinportugal.org)
  • anatomy
  • A representative model of the geometry was constructed by manually analyzing natural variations in 10 patients and incorporating the known anatomy from textbooks of neurosurgical anatomy. (ahajournals.org)
  • therapeutic
  • To elucidate mechanisms of renal injury due to ischemia and possible therapeutic strategies murine models are intensively required 7-13 . (jove.com)
  • structure
  • The first stint focuses on medical image analysis, virtual model reconstruction, and patient-specific CFD simulations of cerebral aneurysms and fluid-structure interaction. (utaustinportugal.org)
  • Evaluation
  • We performed a systematic evaluation of a novel model for isolated renal artery occlusion in mice, which specifically avoids the use of clamping or suturing the renal pedicle 14 . (jove.com)