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  • 2016
  • H. T. Banks , J. E. Banks , R. A. Everett and J. D. Stark , An adaptive feedback methodology for determining information content in stable population studies, Mathematical Biosciences and Engineering , 13 (2016), 653-671. (aimsciences.org)
  • vitro
  • Furthermore, studies of this complex vascular structure in patients, animal models, or experimental in vitro models are difficult. (ahajournals.org)
  • Existing methods for studying voice production include in vivo experimentation using human and animal subjects, in vitro experimentation using excised larynges and synthetic models, and computational modeling. (jove.com)
  • Inherent to the groups approach is the testing of these models and devices using data obtained from our in vitro setups, from isolated (slaughterhouse) in vivo beating heart experiments, and data from animals and patients, obtained in collaboration with our academic and clinical partners. (tue.nl)
  • Research in the node employs cutting edge techniques that utilise both in vitro and in vivo systems performed across a wide range of species ranging from invertebrates, through fish to man as well as cell and organ culture models. (sheffield.ac.uk)
  • respiratory
  • The resulting integrated model will provide mechanistic explanations for the phenomena of respiratory sinus-arrhythmia and cardio-ventilatory coupling observed under normal conditions, and the loss of these properties during sepsis. (frontiersin.org)
  • disease
  • Furthermore, the epidemiology and pathophysiology of perioperative cardiovascular disease is poorly understood. (sacemaquarterly.com)
  • In summary, the combined protocol strategy can be readily applied for quantitative TATS network studies during physiological myocyte adaptation or disease changes, comparison of different cardiac or skeletal muscle cell types, phenotyping of transgenic models, and pharmacological or therapeutic interventions. (jove.com)
  • Both of these noninvasive measures of vascular dysfunction are independent predictors of future cardiovascular events in patients with and without kidney disease. (jove.com)
  • Given the expense and time involved in creating animal models of disease, it is critical that researchers have tools to accurately assess phenotypic expression of disease. (jove.com)
  • The use of primary cardiomyocytes (CMs) in culture has provided a powerful complement to murine models of heart disease in advancing our understanding of heart disease. (jove.com)
  • The use of these techniques will help to develop mechanistic insight into signaling pathways that regulate cellular excitability, Ca 2+ dynamics and contractility and provide a much more physiologically relevant characterization of cardiovascular disease. (jove.com)
  • The model needs to be applicable to a wider population including different ethnic groups, different countries and to those with and without cardiovascular disease. (biomedcentral.com)
  • A worked example is given calculating the 10-year coronary heart disease risk for a 57 year-old non-diabetic male with no personal or family history of cardiovascular disease, who smokes 30 cigarettes a day and has a systolic blood pressure of 137 mmHg, a total cholesterol (TC) of 6.2 mmol/l, a high density lipoprotein (HDL) of 1.3 mol/l, and a body mass index of 21. (biomedcentral.com)
  • In clinical medicine, cardiovascular risk is increasingly accepted as the appropriate criterion to use to identify those who will most benefit from interventions designed to prevent cardiovascular disease and death. (biomedcentral.com)
  • This paper describes a cardiovascular disease (CVD) model which has been developed specifically for use in consultations with patients as an aid to risk communication and to shared decision making. (biomedcentral.com)
  • Most CVD models focus on coronary heart disease (CHD) events, such as myocardial infarction. (biomedcentral.com)
  • A cardiac or cardiovascular surgeon could treat: Coronary artery disease or blockages of the arteries in the heart, blockages in the heart valves, leaking heart valves, abnormal enlargement or aneurysms of the large arteries in the chest, heart failure, and atrial fibrillation. (prezi.com)
  • With a blend of theoretical modeling and experimentation, these studies have provided new insights into our understanding of the mechanisms that drive heart development, as well as mechanical abnormalities that may play a role in congenital heart disease. (nanohub.org)
  • These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. (springer.com)
  • Arterial
  • An automated, closed-loop 1D-0D modelling framework was developed, and we demonstrate its efficacy in (1) reproducing measured multi-variate cardiovascular variables (pulse pressure, total peripheral resistance and cardiac output) and (2) providing automated estimates of variables that have not been measured (uterine arterial and venous blood flow, pulse wave velocity, pulsatility index). (springer.com)
  • It is also the first model capable of capturing wave propagation phenomena in the utero-ovarian circulation, which are important for the accurate estimation of arterial stiffness in contemporary obstetric practice. (springer.com)
  • Transgenic and toxic models of pulmonary arterial hypertension (PAH) are widely used to study the pathophysiology of PAH and to investigate potential therapies. (jove.com)
  • mechanics
  • Biofliud Mechanics in Cardiovascular Systems is one of the first books to take an interdisciplinary approach to the subject. (indigo.ca)
  • The goals are to help train a new generation of researchers with in-depth knowledge of mechanics and biology and to help engineers and biologists apply biomechanical approaches in biomolecular, cellular, tissue-level, animal model studies. (nanohub.org)
  • 2017
  • 2017 ). The creation and development of the placenta (a specialised organ that facilitates nutrient exchange between maternal and foetal systems) represent a significant change compared with non-pregnant cardiovascular structure. (springer.com)
  • H. T. Banks , J. E. Banks , J. Rosenheim and K. Tillman , Modelling populations of Lygus hesperus cotton fields in the San Joaquin Valley of California: The importance of statistical and mathematical model choice, Journal of Biological Dynamics , 11 (2017), 25-39. (aimsciences.org)
  • Prasad V, Lynch JC, Pasakarnis CL, Thorsen JE, Filbin MR, Reisner AT, Heldt T. "Classification models to predict vasopressors administration for septic shock in the emergency department," Proceedings of the 39th Annual Conference of the IEEE Engineering in Medicine and Biology Society, pp. 2650-2653, 2017. (mit.edu)
  • Syed IM, Heldt T. "Model-based estimation of radial artery blood pressure from recordings of the Nexfin monitor," Proceedings of the 39th Annual Conference of the IEEE Engineering in Medicine and Biology Society, pp. 1692-1695, 2017. (mit.edu)
  • constitutive
  • These can be further augmented by combining uncertainty in the choice of appropriate constitutive models for the blood and the boundary conditions. (utaustinportugal.org)
  • In the current study, a large strain time-dependent constitutive model of human vocal fold tissue is used to investigate effects of phonatory posturing cyclic strain in the range of 1 Hz to 10 Hz. (jove.com)
  • Simulations
  • The first stint focuses on medical image analysis, virtual model reconstruction, and patient-specific CFD simulations of cerebral aneurysms and fluid-structure interaction. (utaustinportugal.org)
  • Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. (springer.com)
  • geometry
  • A model of the circle of Willis geometry was approximated as a network of tubes around cubic curves. (ahajournals.org)
  • A representative model of the geometry was constructed by manually analyzing natural variations in 10 patients and incorporating the known anatomy from textbooks of neurosurgical anatomy. (ahajournals.org)
  • Synthetic models can be fabricated with systematic changes to geometry and material properties, allowing for the study of healthy and unhealthy human phonatory aerodynamics, structural dynamics, and acoustics. (jove.com)
  • This is a mathematical model of geometry and fibrous structure of the heart. (prezi.com)
  • human
  • Consequently, one- and two-layer synthetic vocal fold models have exhibited disadvantages 3,6,8 such as higher onset pressures than what are typical for human phonation (onset pressure is the minimum lung pressure required to initiate vibration), unnaturally large inferior-superior motion, and lack of a "mucosal wave" (a vertically-traveling wave that is characteristic of healthy human vocal fold vibration). (jove.com)
  • Ethanol administration to pregnant rodents has been used to model human exposure during the first and second trimesters of pregnancy. (jove.com)
  • The editors of this important compendium view their task as a contribution to modeling and simulating human vision by machine. (springer.com)
  • murine models
  • To elucidate mechanisms of renal injury due to ischemia and possible therapeutic strategies murine models are intensively required 7-13 . (jove.com)
  • Published echocardiography protocols in murine models of PAH are lacking. (jove.com)
  • experiments
  • Overcoming some of the limitations of excised larynx experiments, synthetic vocal fold models are emerging as a complementary tool for studying voice production. (jove.com)
  • Simulation
  • The simulation results confirm the adaptability of our model and its usefulness for diagnostic or educational purposes. (asme.org)
  • Algorithm
  • Here, we addressed this issue by developing a mathematical algorithm based on support vector machine (SVM) through integrating the expression levels of multi-biomarkers. (jove.com)
  • mathematicians
  • zebrafish experimental models with multidisciplinary work with engineers, physicists and mathematicians to answer questions about normal immunity to infection and opportunistic infections of the immunocompromised. (sheffield.ac.uk)
  • describe
  • We describe a vapor chamber paradigm that can be used to model exposure to ethanol, with minimal handling, during all three trimesters. (jove.com)
  • responses
  • Effects of wearing compression stockings on cardiovascular responses. (biomedsearch.com)
  • To investigate the effects of wearing compression stockings on cardiovascular responses, the heart rate (HR), cardiac output (Q) measured by CO2 rebreathing method, and oxygen intake were measured at rest in a supine position for 40 min and standing position for 120 min. (biomedsearch.com)
  • blood flow
  • This is the first model capable of estimating volumetric blood flow to the uterus via the utero-ovarian communicating arteries. (springer.com)
  • Heart
  • We generate predictions using mathematical models, then test these predictions experimentally by measuring calcium and transmembrane voltage in heart cells. (mssm.edu)
  • They can also be called cardiac surgeons, cardiovascular surgeons, general thoracic surgeons, and congenital heart surgeons. (prezi.com)
  • They analyze models such as this one, to learn more about the heart and how to make their surgery more successful. (prezi.com)
  • He and his students have developed the first mathematical models for cardiovascular growth and morphogenesis and were the first to measure stress, strain and interstitial pressure in the heart of the early chick embryo. (nanohub.org)
  • dynamical
  • In this work, we present a dynamical one-dimensional network model of haemodynamics. (springer.com)
  • This allows us to investigate how many data are required to have confidence in model parameter estimates in order to employ dynamical modeling to infer population dynamics. (aimsciences.org)
  • Data collected according to this procedure along with dynamical modeling will allow us to estimate population dynamics from presence/absence-based data sets through the development of a scaling relationship. (aimsciences.org)
  • complexity
  • The final part is devoted to control and inverse problems, including parameter estimation, uncertainty quantiļ¬cation and the development of reduced-order models that are important when solving problems with high complexity, which would otherwise be out of reach. (cambridge.org)
  • Mathematical modelling should be considered an integral component of perioperative cardiovascular research due to the nature and complexity of the outcomes associated with these studies. (sacemaquarterly.com)
  • rodent
  • Echocardiography is the mainstay of the noninvasive assessment of right ventricular function in rodent models and has the advantage of clear translation to humans in whom the same tool is used. (jove.com)
  • uncertainty
  • Patient-specific case studies to quantify relative bounds to this uncertainty uncovered a dire need for care in the virtual model reconstruction from medical images. (utaustinportugal.org)
  • In the case of aneurysms, the uncertainty due to the virtual model definition is comparable to that when choosing different models for the non-Newtonian behavior of blood. (utaustinportugal.org)
  • H. T. Banks , S. Hu and W. C. Thompson , Modeling and Inverse Problems in the Presence of Uncertainty , CRC Press, New York, 2014. (aimsciences.org)
  • Applications
  • His research interests include mathematical modelling and its applications. (cambridge.org)
  • These applications apear inside the online article and allows readers to interactively explore 3D models. (elsevier.com)
  • H. T. Banks , K. Bekele-Maxwell , L. Bociu , M. Noorman and K. Tillman , The complex-step method for sensitivity analysis of non-smooth problems arising in biology, Eurasian Journal of Mathematical and Computer Applications , 3 (2015), 15-68. (aimsciences.org)
  • This compendium is a solid contribution to the recent literature combining the theories and applications of mathematical modeling to the domain of computer vision. (springer.com)
  • function
  • He is author or coauthor of numerous publications related to secondhand smoke and tobacco control, as well as many papers on cardiovascular function and biostatistics. (ucsf.edu)
  • However, this hypothesis remains to be tested by using definitive loss-of-function animal models. (jove.com)