AnatomyChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Indicator Dilution TechniquesRadioisotope Dilution TechniqueMass SpectrometryGas Chromatography-Mass SpectrometryReproducibility of ResultsReference StandardsIsotopesChromatography, High Pressure LiquidTandem Mass SpectrometrySpectrometry, Mass, Electrospray IonizationIsotope LabelingMagnetic Resonance SpectroscopyCreatinineSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationChromatography, LiquidNitrogen IsotopesOxygen IsotopesDeuteriumCarbon IsotopesMolecular Sequence DataCalibrationAmino Acid SequenceProteomicsBody WaterSpectrometry, Mass, Fast Atom BombardmentSensitivity and SpecificityIndicators and ReagentsLimit of DetectionMolecular StructureSolid Phase ExtractionKineticsProteome
Tandem mass spectroChromatography-mass spectrometryHigh performance liInductively coupled plasStandardized Fourier transforAtomic Absorption SpectrometryRamanThermal ionization massFluorescence SpectrometryRatiosMethodsStableGeochemistryMethodChemometricsElementalDeterminationIsotopicVivoNuclearAnalysesAnalysisDetection limitsAnalyzerQuantificationSensitivityConsistsMeasurementsElementsRocksSamplesSubjectsNeutronSampleConcentrationDemonstrateStudyMolecularFluid
Tandem mass spectro5
  • To measure these biochemical indicators in blood or urine, CDC's Environmental Health Laboratory (Division of Laboratory Sciences, National Center for Environmental Health) used a variety of analytical methods: isotope dilution tandem mass spectrometry, gas chromatography coupled to mass spectrometry, inductively coupled plasma mass spectrometry, atomic absorption spectroscopy, high performance liquid chromatography with different detection modes such as UV-visible and fluorescence, and various immuno-, protein binding, and colorimetric assays. (cdc.gov)
  • Conventionally, amino acid analysis by isotope dilution tandem mass spectrometry (LC-MS/MS) following peptide hydrolysis is employed as a reference method. (bvsalud.org)
  • Methods are mainly based on gas chromatography and (tandem) mass spectrometry, high performance liquid chromatography as well as atomic absorption spectroscopy. (dguv.de)
  • Using tandem mass spectrometry for metabolic disease screening among newborns: a report of a work group. (cdc.gov)
  • Increasingly, tandem mass spectrometry (MS/MS) is being used for newborn screening because this laboratory testing technology substantially increases the number of metabolic disorders that can be detected from dried blood-spot specimens. (cdc.gov)
Chromatography-mass spectrometry3
High performance li1
  • Furthermore, with the most commonly used chemometrics algorithms, it is difficult to accurately extract and discriminate the huge amounts of data generated by mass spectrometry, such as ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF). (hindawi.com)
Inductively coupled plas1
  • This inductively coupled plasma-mass spectroscopy (ICP-MS) method is intended as an alternative analysis to methods such as alpha spectroscopy or thermal ionization mass spectroscopy (TIMS). (eichrom.com)
Standardized Fourier transfor1
  • The milk compositional features were determined by standardized Fourier transform-infrared spectroscopy, and the detection limits for common milk adulterations were investigated. (mdpi.com)
Atomic Absorption Spectrometry1
  • LEAD LEAD - TOTAL mg/L Pb - Atomic Absorption Spectrometry - Direct AspirationLEAD - DISSOLVED mg/L Pb - ICP - MSLEAD - DISSOLVED mg/L Pb - Atomic Absorption Spectrometry &nda. (speciation.net)
Raman4
  • Wang X, Liu Nm, Zhao Yf, Yang F, Zhu Zj, Song D. Research Progress in the Medical Application of Heavy Water, Especially in the Field of D 2 O-Raman Spectroscopy. (medsci.org)
  • Among these, Raman spectroscopy has attracted increasing attention as a highly sensitive molecular imaging technique for studying complex biological systems, including cells, tissues, and various biological materials [ 4 ]. (medsci.org)
  • Raman spectroscopy analyzes the biochemical components of a sample by measuring the inelastic scattering of light by different molecular species, producing a spectrum based on the chemical bonds present within the analyzed samples. (medsci.org)
  • Simultaneously, the results of Raman spectroscopy provide abundant information, which can reflect the biochemical and structural characteristics of the material of interest. (medsci.org)
Thermal ionization mass3
  • However, compared with other types of mass spectrometry, such as thermal ionization mass spectrometry (TIMS) and glow discharge mass spectrometry (GD-MS), ICP-MS introduces many interfering species: argon from the plasma, component gases of air that leak through the cone orifices, and contamination from glassware and the cones. (wikipedia.org)
  • Glow Discharge Mass Spectrometry (GDMS) and Thermal Ionization Mass Spectrometry (TIMS), that require a two-stage process: Insert sample(s) into a vacuum chamber, seal the vacuum chamber, pump down the vacuum, energize sample, thereby sending ions into the mass analyzer. (wikipedia.org)
  • Applying the procedure developed in this study to the homogenized Allende meteorite powder sample prepared by the Smithsonian Institution, Washington, D. C., US and several geological reference samples issued by the Geological Survey of Japan and the US geological Survey, precision and accuracy of the data obtained were evaluated and the accuracy was found to be equivalent to isotope dilution values obtained by thermal ionization mass spectrometry. (elsevierpure.com)
Fluorescence Spectrometry1
  • Harvey P., Taylor D., Hendry R., Bancroft F. An accurate fusion method for the analysis of rocks and chemically related materials by X-ray fluorescence spectrometry. (urfu.ru)
Ratios2
  • Stable carbon and nitrogen isotope ratios (δ 13 C/δ 15 N) in the bone collagen and other hard tissues of marine species serve as proxies for primary productivity and food web interactions. (frontiersin.org)
  • 1.4 Corrections to the measured isotopic ratios for mass bias effects are made by determining and applying a mass bias factor (see 13.3.1). (eichrom.com)
Methods3
  • Currently, the commonly used methods to quantify heavy water concentration include the density method, mass spectrometry, and spectroscopy techniques [ 3 ]. (medsci.org)
  • Ebihara, M, Hayano, K & Shirai, N 2020, ' Determination of trace rare earth elements in rock samples including meteorites by ICP-MS coupled with isotope dilution and comparison methods ', Analytica Chimica Acta , vol. 1101, pp. 81-89. (elsevierpure.com)
  • Reaction gas methods can use either on-mass or mass-shift measurement. (spectroscopyonline.com)
Stable4
  • Stable isotope 13C labeling is an important tool to analyze cellular metabolic flux. (biomed.news)
  • However, in addition to carbon, other elements such as oxygen in the nature also have natural stable isotopes (e.g., 17O, 18O). (biomed.news)
  • The method was established based on the stable isotope-dilution liquid chromatography-tandem mass spectroscopy (ID-LC-MS/MS) technique. (biomed.news)
  • The combination of high-resolution LC-MS-based untargeted metabolomics with stable isotope tracing provides a global overview of the cellular fate of precursor metabolites. (acs.org)
Geochemistry1
  • Search entire documentExplore New Opportunities in Geochemistry,Mineral Analysis, and Nuclear Science With theAgilent 8900 ICP-QQQAgilent atomic spectroscopy instruments are known for their robustness,excellent control of. (labrulez.com)
Method10
  • Using synthetic standards of five abundant substances, impurity mass fractions calculated via the relative response method are in reasonable agreement with those determined from standard addition experiments, whereas external calibration measurements frequently overestimate impurity amounts. (bvsalud.org)
  • In this paper, we proposed a method for construction of correction matrix based on Python language for correcting the measurement errors due to natural isotope distribution. (biomed.news)
  • To circumvent issues related to throughput, sample processing, and dependence on a reference material, Srivastava and Hodges (2018) applied a linear absorption spectroscopy method to measure the absolute number density of gaseous elemental mercury. (ilmexhibitions.com)
  • Combining isotope dilution mass spectrometry with a calibration method and choosing appropriate internal standard elements, 14 lanthanides (rare earth elements, REEs) were precisely and accurately determined for rock samples by using quadruple ICP-MS instruments. (elsevierpure.com)
  • An enriched spike of 149 Sm was used to determine Sm content by an isotope dilution method. (elsevierpure.com)
  • This method consists of two approaches: isotope dilution mass spectrometry (IDMS) for the determination of total metals and speciated isotope dilution mass spectrometry (SIDMS) for the determination o. (speciation.net)
  • This MDHS describes a method for measuring exposure to a range of metal and metalloid elements in workplace air using inductively coupled plasma-atomicemission spectrometry (ICP-AES). (speciation.net)
  • This method describes the collection and subsequent analysis of airborne metal and metalloid particulate by Inductively Coupled Argon Plasma-Atomic Emission Spectroscopy (ICAP-AES). (speciation.net)
  • Also, while this test method covers only those isotopes listed above, the instrumental technique may be expanded to cover other long-lived radioisotopes since the preparation technique includes the preconcentration of the actinide series of elements. (eichrom.com)
  • Haukka M.T., Thomas I.L. Total X-ray fluorescence analysis of geological samples using a low-dilution lithium metaborate fusion method matrix correction major elements. (urfu.ru)
Chemometrics1
  • A special volume of Journal of Statistical Software (JSS) dedicated to Spectroscopy and Chemometrics in R was published in January 2007. (wustl.edu)
Elemental1
  • Agilent ICP-MS JournalApril 2017 - Issue 68Inside this Issue2-3Direct, Rapid Analysis of Undiluted Seawater usingICP-MS with the HMI Aerosol Dilution System3On-Demand Webinar: Updated European Standards forWater Analysis Using ICP-MS5Ultrasensitive High Throughput Elemental Speciation Analysis using GC-ICP-MS6An Overview of the Role. (labrulez.com)
Determination1
  • In this study, we propose a novel approach for the determination of total dissolved nitrogen (TDN) in seawater combining high-precision isotope dilution GC-MS with persulfate digestion. (bvsalud.org)
Isotopic2
  • It can detect different isotopes of the same element, which makes it a versatile tool in isotopic labeling. (wikipedia.org)
  • This makes the isotopic information of elements other than the 13C marker interspersed in the isotopic distribution measured by the mass spectrometry, especially that of the molecules containing many other elements, which leads to large errors. (biomed.news)
Vivo1
  • Marek EM, Koslitz S, Weiß T , Fartasch M, Schlüter G, Käfferlein HU, Brüning T. Quantification of N-phenyl-2-naphthylamine by gas chromatography and isotope-dilution mass spectrometry and its percutaneous absorption ex vivo under workplace conditions. (dguv.de)
Nuclear1
  • By contrast, quantitative nuclear magnetic resonance (qNMR) spectroscopy allows for quantitation of intact peptides, thus eliminating potential bias due to hydrolysis. (bvsalud.org)
Analyses1
  • The National Center for Environmental Health in Atlanta, Georgia, conducted the laboratory analyses using gas chromatography/isotope dilution-high resolution mass spectroscopy. (cdc.gov)
Analysis3
  • 1] R. Djingova, B. Zlateva, I. Kuleff, On the possibilities of inductively coupled plasma mass spectrometry for analysis of archaeological bones for reconstruction of paleodiet, Talanta, 63 (2004) 785-789. (icomos.org)
  • The aims of this study were, first, to confirm that mass spectrometric analysis of an array of hormones and organic acids would yield similar results in both liquid and dried urine, and, second, to determine if collection of four dried spot urine samples could be substituted for a 24-h collection when measuring reproductive hormones. (biomedcentral.com)
  • Lee R.F., McConchine D.M. Comprehensive major and trace element analysis of geological materials by X-ray fluorescence using low dilution fusions. (urfu.ru)
Detection limits1
  • The minor isotopes 47 Ti (7.44% abundance) and 49 Ti (5.41% abundance) are therefore typically used for Ti quantitation by ICP-MS, so sensitivity and detection limits are poorer than they would be if a major isotope was available. (spectroscopyonline.com)
Analyzer1
  • multiple vacuum stages separate by differential apertures (holes), the ions created in the argon plasma are, with the aid of various electrostatic focusing techniques, transmitted through the mass analyzer to the detector(s) and counted. (wikipedia.org)
Quantification1
  • This methodology enables detection of putative metabolites from biological samples and simultaneous quantification of the pattern and extent of isotope labeling. (acs.org)
Sensitivity1
  • The sensitivity and selectivity of high-resolution mass spectrometry (MS) renders it an indispensable technique in this arena. (bvsalud.org)
Consists1
  • An inductively coupled plasma (ICP) for spectrometry is sustained in a torch that consists of three concentric tubes, usually made of quartz, although the inner tube (injector) can be sapphire if hydrofluoric acid is being used. (wikipedia.org)
Measurements3
  • The mass balance approach has also been employed for peptide purity measurements, whereby the purity is defined by the sum of the mass fraction of all impurities identified. (bvsalud.org)
  • Historically, in this program the mercury emitted by a NIST prime Hg generator was value-assigned on the SI using an SRM 3133® Hg standard combined with isotope dilution cold vapor inductively coupled mass spectrometry measurements. (ilmexhibitions.com)
  • While direct measurements with inductively coupled plasma-mass spectrometry (ICP-MS) are highly efficient and feasible, only total Gd can be detected with this approach. (univie.ac.at)
Elements2
  • ICP-MS can measure Ti at low levels, although three of its five isotopes ( 46 Ti, 48 Ti, and 50 Ti) are overlapped by minor isotopes of other elements ( 46 Ca, 48 Ca, 50 V, and 50 Cr). (spectroscopyonline.com)
  • In sample matrices that contain high levels of Ca, P, C, Cl, or S, common matrix elements in many natural materials, all of the Ti isotopes can also be affected by polyatomic interferences including CaH + , PO + , SOH + , and CCl + (2). (spectroscopyonline.com)
Rocks1
  • Crystallization ages on biotite and hornblende from plutonic rocks range from about ~60 to ~63 Ma, while a sericite alteration age in plutonic rocks altered by a dike swarm also is around ~63 Ma. (usgs.gov)
Samples2
  • With a sample dilution factor of 200 resulting from the preparation, this equates to a concentration range in the samples from 1 to 1000 �g/g. (eichrom.com)
  • For those samples estimated to be above that range by initial activity screening, a smaller aliquot is taken to a dilution of 1000, thereby extending the range to 5000 �g/g. (eichrom.com)
Subjects1
  • Cholesterol and oxidized cholesterol metabolite serum levels of FH and of healthy, gender/age matched control subjects were measured by combined gas chromatography - mass spectroscopy. (biomedcentral.com)
Neutron2
  • while they have different neutron numbers, mass numbers, and physical properties, they have the same number of protons, number of outermost electrons, and chemical properties. (medsci.org)
  • In this study, an electromagnetic isotope separation technique was applied after neutron irradiation to boost the specific activity by separating 169 Er from 168 Er targets. (frontiersin.org)
Sample4
  • Inductively coupled plasma mass spectrometry (ICP-MS) is a type of mass spectrometry that uses an inductively coupled plasma to ionize the sample. (wikipedia.org)
  • What makes Inductively Coupled Plasma Mass Spectrometry (ICP-MS) unique to other forms of inorganic mass spectrometry is its ability to sample the analyte continuously, without interruption. (wikipedia.org)
  • Quadrupole inductively coupled plasma-mass spectrometry (ICP-QMS) is a standard technique for analyzing trace metals in many sample types including environmental, food, and biological materials. (spectroscopyonline.com)
  • The results of the 2 sample sets proved and validated that mid-infrared spectroscopy was a promising and reliable technique for SSR detection. (puvanameta.com.my)
Concentration1
  • The resulting relative standard uncertainties are 0.5% across the mass concentration range 0.25 μg m-3 to 1000 μg m-3. (ilmexhibitions.com)
Demonstrate1
  • Additional advanced mass spectrometry-based methodology enabled to demonstrate simultaneous transport of organic pigments, heavy metals and titanium dioxide from skin to regional lymph nodes. (nature.com)
Study2
  • As a new type of probe, the heavy isotope of water has been widely used in the study of cell development, metabolism, tissue homeostasis, aging, and tumor heterogeneity. (medsci.org)
  • In this study, PMBL was defined as patients with a dominant mass within the anterior mediastinum, irrespective of the tumor size. (angiogenesis-blog.com)
Molecular1
  • The relative molecular mass of heavy water, 20.0275 Mr, is higher than that of water (H 2 O, 18.0153 Mr) by about 11%, hence the name "heavy" water. (medsci.org)
Fluid2
  • We show that before eruption, Br and Cl were efficiently partitioned from the gas-saturated magma into a separate fluid phase, and we calculate the mass of halogens in the fluid phase. (eurekalert.org)
  • If the fluid phase were erupted, the large mass of Br and Cl could have severely impacted the atmospheric chemistry upon eruption. (eurekalert.org)