• Thermo Fisher Scientific have introduced a new-generation triple quadrupole liquid chromatography-mass spectrometry (LC-MS) platform designed to transform quantitation experiments with extreme sensitivity, productivity, precision and usability. (labmate-online.com)
  • Among the highlights of the week, the 2008 Award for Distinguished Contribution in Mass Spectrometry, which recognizes a focused achievement in or contribution to fundamental or applied mass spectrometry, was presented to Dr. Alexander Makarov, Director of Global Reseaarch for Life Sciences Mass Spectrometry, Thermo Fisher Scientific, Inc., for his leading role in the creation of a high-performance orbital electrostatic trap, which he termed the 'orbitrap. (chromatographyonline.com)
  • Because a compact circuit can generate a high electric field, decreasing the size of the voltage-generating system does not significantly affect to the miniaturization of time-of-flight mass spectrometry (TOF) and electric sectors which use only the electric field to separate ions. (wikipedia.org)
  • Analysis of complex mixtures with gas chromatography coupled with high-resolution time-of-flight mass spectrometry (GC-HRTOFMS) can produce a large amount of data. (jeolusa.com)
  • In this study, state-of-the-art instrumentation two-dimensional gas chromatography (GC × GC) coupled photoionization─time of flight mass spectrometry was employed to investigate the composition of dodecene products produced from olefin oligomerization. (jeolusa.com)
  • Trapped ion mobility spectrometry (TIMS) combined with quadrupole time of flight mass spectrometry (Q-TOF). (lu.se)
  • Following World War II the techniques of manipulating very short electrical pulses allowed the construction of the time-of-flight mass spectrometer , in which a short emission of ions is released from the source and their arrival times recorded after having traversed a distance sufficiently long to sort out the different speeds. (britannica.com)
  • The application of superimposed radio frequency and constant potentials between four parallel rods can be shown to act as a mass separator in which only ions within a particular mass range will perform oscillations of constant amplitude and be collected at the far end of the analyzer. (britannica.com)
  • New applications and new developments have gone hand in hand to create a complex array of instruments, but all may be understood by tracing the ions through three basic elements: an ion source, a method of analyzing the ion beams according to their mass-to-charge ratio, and detectors capable of measuring or recording the currents of the beams. (britannica.com)
  • Smaller mass analyzers require smaller control system to generate adequate electric field and magnetic field strength, which are two fundamental fields separating ions based on their mass-to-charge ratio. (wikipedia.org)
  • Cotter at Johns Hopkins University used a pulsed extraction in linear time of flight mass analyzer and the ions are accelerated to with higher energy of 12 keV to enable detection of high-mass. (wikipedia.org)
  • Mass spectrometer that separates ions by m/z in a field-free region after acceleration through a fixed accelerating potential. (epfl.ch)
  • Spock is a highly precise isotope ratio mass spectrometer , which uses a magnetic field to separate and measure molecules of different masses (a measure of how much matter is in an object) by bending ions of different charges at different radii. (noaa.gov)
  • A QMS detects and quantifies chemical species by first ionizing the molecules and/or atoms in a gas stream and then separating these ions by mass/charge (m/e) ratio. (mks.com)
  • The ions are separated according to their m/e ratio by a quadrupole mass filter and detected by a Faraday plate or secondary electron multiplier. (mks.com)
  • As a result, the m/z axis of the mass spectrum is equal to the mass of the ions, thus making it easy to interpret polymer distributions. (jeolusa.com)
  • The mass spectrometer ionizes the derivatized amino acids, generating charged ions that are subsequently analyzed based on their mass-to-charge ratio (m/z). (pharmiweb.com)
  • The ions, along with the argon, enter the mass spectrometer through an interface that separates the ICP (at atmospheric pressure, ~760 torr) from the mass spectrometer (operating at a pressure of 10-5 torr), and are finally selectively counted in rapid sequence at the detector allowing individual isotopes of an element to be determined. (cdc.gov)
  • The TSQ Quantiva triple quadrupole mass spectrometer employs Active Ion Management (AIM) to optimise ion creation and transmission from the source to the detector, resulting in extreme sensitivity. (labmate-online.com)
  • The TSQ Endura triple quadrupole mass spectrometer shares much of the advanced technology of the TSQ Quantiva MS, but was designed to deliver higher uptime than any competitive triple quadrupole instrument. (labmate-online.com)
  • The 6475 triple quadrupole mass spectrometer monitors its own vitals, giving you a real-time overview of the system's health. (agilent.com)
  • This sensitive and robust triple quadrupole mass spectrometer is used for analysis of low (ppb) levels of environmental compounds and biomarkers. (lu.se)
  • Professor Klaus Dreisewerd , Leader Section for Biomedical Mass Spectrometry at the University of Muenster in Germany, and the pioneer of MALDI-2, said: "In the last 35 years, MALDI has become a unique and rapid analytical tool for a wide variety of applications. (bruker.com)
  • The new JMS-Q1600GC UltraQuad™ SQ-Zeta Single Quad Mass Spectrometer of JEOL is our 6th generation high-end Gas Chromatograph Quadrupole Mass Spectrometer (GC-QMS) based on JEOL's 50 years of MS technologies and experience. (jeolusa.com)
  • Pyrolysis gas chromatograph quadrupole mass spectrometer (Py-GC-QMS) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOFMS) are powerful tools for analyzing polymeric materials. (jeolusa.com)
  • We prior knowledge of nucleic acid sequence information is use broad-range PCR to generate amplification products required to develop these tests, they are not able to identi- from the broadest possible grouping of organisms, followed fy unanticipated, newly emergent, or previously unknown by electrospray ionization mass spectrometry and base infectious organisms. (cdc.gov)
  • Secondary electrospray ionization mass spectrometry (SESI-MS) enables the detection of volatile organic compounds (VOCs) without the need for any sample pretreatment. (jove.com)
  • A miniature mass spectrometer (MMS) is a type of mass spectrometer (MS) which has small size and weight and can be understood as a portable or handheld device. (wikipedia.org)
  • The most common type of mass spectrometer (MS) associated with a gas chromatograph (GC) is the quadrupole mass spectrometer, sometimes referred to by the Hewlett-Packard (now Agilent) trade name "Mass Selective Detector" (MSD). (iitk.ac.in)
  • Research in biological chemistry at Cardiff covers a diverse range of themes including enzyme catalysis and synthetic biology, manipulating biomolecular interactions, biomolecular NMR spectroscopy and mass spectrometry, and organic synthesis and medicinal chemistry. (cardiff.ac.uk)
  • In-situ characterization of metal nanoparticles and their organic coatings using laser vaporization aerosol mass spectrometry. (lu.se)
  • The new methodology and interpretation can improve methods that use aerosol mass spectrometry for the source apportionment of combustion emissions. (lu.se)
  • Three types of process mass spectrometers were described: the magnetic field type, the time of flight type, and the quadrupole mass spectrometer. (cdc.gov)
  • The Q Exactive UHMR Hybrid Quadrupole-Orbitrap Mass Spectrometer is Thermo Fisher Scientific's first mass spectrometry platform to combine substantially increased sensitivity and mass resolution at high m/z , with MS 2 and pseudo-MS 3 capabilities - creating a unique and powerful analytical solution for the investigation of structure and heterogeneity of protein complexes. (thermofisher.com)
  • Gas-phase chemistry in the GC Orbitrap Mass Spectrometer. (mpg.de)
  • 2018. Exploring ECD on a Benchtop Q Exactive Orbitrap Mass Spectrometer. . (oregonstate.edu)
  • 2018. Sequencing Grade Tandem Mass Spectrometry for Top-Down Proteomics Using Hybrid Electron Capture Dissociation Methods in a Benchtop Orbitrap Mass Spectrometer. . (oregonstate.edu)
  • The mass spectrometer does this by breaking each molecule into ionized fragments and detecting these fragments using their mass to charge ratio. (iitk.ac.in)
  • The CUBES-SIL has three magnetic sector, gas-source, isotope ratio mass spectrometers with various peripherals and custom-built inlet systems. (colorado.edu)
  • Mass spectrometer measures the mass-to-charge ratio in an element. (dnatube.com)
  • Allows identification and quantification of amino acids by measuring their mass-to-charge ratio. (pharmiweb.com)
  • Gas-Isotope-ratio mass spectrometry (G-IRMS) allows the precise measurement of mixtures of naturally occurring light stables isotopes. (lu.se)
  • 13C by isotope ratio mass spectrometry. (cdc.gov)
  • Improved detection, versatility, and sensitivity for protein complex subunit analysis and biopharmaceutical characterization with an extended optional mass range up to m/z 16,000. (thermofisher.com)
  • A Fourier-transform spectrometer provides a conventional absorption spectrometer-type spectrum but has greater speed, resolution, and sensitivity. (britannica.com)
  • The Thermo Scientific Orbitrap Astral mass spectrometer combines fast throughput, high sensitivity and deep proteome coverage to allow researchers to uncover proteins that previously evaded detection. (labonline.com.au)
  • Researchers developed high-sensitivity spectrometers with high wavelength accuracy, high spectral resolution and broad operation bandwidth. (labonline.com.au)
  • This collaboration is focused on developing specific applications for use with a mass spectrometry (MS) system that combines both qualitative and quantitative analysis at high resolution and high sensitivity with accurate mass. (genengnews.com)
  • With its dramatically increased sensitivity and accessible range of chemical classes, the novel MALDI-2 source option can now further enhance mass spectrometry-based, non-targeted tissue analysis. (bruker.com)
  • Combining mass spectrometry with separation techniques such as HPLC or CE can improve the accuracy and sensitivity of amino acid analysis. (pharmiweb.com)
  • Gas chromatography-mass spectrometry (GC-MS) is a method that combines the features of gas-liquid chromatography and mass spectrometry to identify different substances within a test sample. (iitk.ac.in)
  • Asati A, Satyanarayana GNV, Panchal S, Thakur RS, Ansari NG, Patel DK (2017) Ionic liquid based vortex assisted liquid-liquid microextraction combined with liquid chromatography mass spectrometry for the determination of bisphenols in thermal papers with the aid of response surface methodology. (springer.com)
  • Proposed NIOSH 9106 for Methamphetamine and Illicit Drugs, Precursors, and Adulterants by Liquid-Liquid Extraction and Gas Chromatography-Mass Spectrometry (GC/MS) is a sampling and analytical method that will be included in the NIOSH Manual of Analytical Methods, 5th edition. (cdc.gov)
  • NIOSH 9109 is a Solid Phase Extraction Gas Chromatography-Mass Spectrometry (GC/MS) method and NIOSH 9111 is a Liquid Chromatography-Mass Spectrometry (LC/MS) method. (cdc.gov)
  • Tweaking and fine-tuning your liquid chromatography/mass spectrometry system to optimize analytical performance is challenging and time consuming. (agilent.com)
  • Gas chromatography mass spectrometry is also available for the analysis of volatile compounds, as well as a state-of-the-art pipetting robot for automated sample preparation. (lu.se)
  • The standard experiment is to separate the proteins, e.g. by 2D gel electrophoresis, digest the proteins with a highly specific enzyme, measure the masses of the peptide fragments with a mass spectrometer (typically a MALDI-TOF mass spectrometer) and then compare the peptide monoisotopic masses with expected monoisotopic masses from a database (protein or DNA database). (lu.se)
  • SVEVs isolated from lyophilized venoms collected from four different species of snakes ( Agkistrodon contortrix contortrix , Crotalus atrox , Crotalus viridis and Crotalus cerberus oreganus ) were analyzed by mass spectrometry-based proteomic, which allowed the identification of proteins belonging to eight main functional protein classes such as SVMPs, serine proteinases, PLA 2 , LAAO, 5′nucleotidase, C-type lectin, CRISP and Disintegrin. (nature.com)
  • In general, beam-type mass analyzers, such as TOF and sector mass analyzers, are much larger than ion trap type such as Paul trap, Penning trap or Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR). (wikipedia.org)
  • Additionally, ion trap mass analyzers can be used to perform multistage MS/MS in a single device. (wikipedia.org)
  • Multiple fragmentation techniques - CID and HCD with optional UVPD, ETD, PCTR - are available at any stage of MS, with subsequent mass analysis in either the ion trap or ultra-high resolution Orbitrap mass analyzer. (thermofisher.com)
  • Another relatively common detector is the ion trap mass spectrometer. (iitk.ac.in)
  • Bruker HCT Ion Trap Mass Spectrometer from Bruker Daltonics is located in the Analytical Lab, room 363 in the Science building on the Boise State University campus. (boisestate.edu)
  • The Thermo Polaris Q GC/MSn Benchtop Ion Trap Mass Spectrometer complete with Thermo Trace Gas Chromatograph, external vacuum pump, and XCalibur PC workstation. (boisestate.edu)
  • Some newer RGAs employ an ion trap as a mass analyzer rather than a quadrupole. (mks.com)
  • This system uses an autoresonant ion trap mass spectrometer gauge rather than a quadrupole mass analyzer. (mks.com)
  • The analyses were performed in selected ion monitoring mode on a linear ion trap mass spectrometer. (springer.com)
  • With new capabilities for multiplexed quantitative proteomics and native protein characterization, the Thermo Scientific Orbitrap Ascend Tribrid mass spectrometer delivers ultimate experimental throughput, versatility, and ease-of-use. (thermofisher.com)
  • Demonstration of m/z 16,000 mass range on purified GroEL 800 kDa protein on a single Orbitrap scan at 7500 resolution at m/z 200. (thermofisher.com)
  • With its superior ability to perform native intact mass and top-down analyses, the Q Exactive UHMR mass spectrometer provides unprecedented structural detail which you cannot see with other methods, enabling deeper understanding of protein function, disease mechanisms, potential drug targets, and biotherapeutic compounds. (thermofisher.com)
  • The Q Exactive UHMR mass spectrometer enables native MS analysis of large protein-nucleic acid assemblies that require high resolution and very efficient transmission in the ultra-high mass range. (thermofisher.com)
  • Native top-down analysis of the AmtB membrane protein complex enabled by high mass quadrupole selection and efficient HCD fragmentation. (thermofisher.com)
  • Low-ppm mass accuracy allowed confident identification of AmtB protein. (thermofisher.com)
  • Waters Corporation has announced a new fragmentation technique and an imaging option for its high-resolution mass spectrometers, giving research scientists working across a broad range of end markets including biomedical, biopharmaceutical and food research, greater experimental freedom to explore the intricacies of peptides, proteins, and protein complexes. (technologynetworks.com)
  • 3) macromolecules: understanding of the mass spectrometry of polymer and intact protein, experience in using the technology of ion mobility and H / D exchange. (nature.com)
  • Refeyn has unveiled the MassFluidix High Concentration (HC) microfluidic system, which extends the analytical strength of mass photometry to high-concentration protein samples. (labonline.com.au)
  • The Thermo Scientific Orbitrap Ascend Tribrid mass spectrometer offers capabilities for multiplexed proteomics and native protein characterisation. (labonline.com.au)
  • An Easy nL nano liquid chromatographic system is coupled to the mass spectrometer through the nanoelectrospray source for protein characterization. (boisestate.edu)
  • Mass spectrometry is among the most powerful analytical techniques available for protein characterization. (kbibiopharma.com)
  • This study examined if leucine, arginine or glycine supplementation in adult obese patients (body mass index of 33 ± 4 kg/m²) consuming a Brazilian low energy and protein diet (4.2 MJ/day and 0.6 g protein/kg) affects protein and amino acid metabolism. (scielo.br)
  • This study examined if leucine, arginine or glycine supplementation in adult obese patients (body mass index of 33 ± 4 kg/m 2 ) consuming a Brazilian low energy and protein diet (4.2 MJ/day and 0.6 g protein/kg) affects protein and amino acid metabolism. (scielo.br)
  • The strategy therefore promises reliable automated user- independent protein identification using peptide mass fingerprints. (lu.se)
  • Mass spectrometry combined with database searching is today the preferred method for protein identification. (lu.se)
  • After the urine sample is diluted, the liquid samples are introduced into the mass spectrometer through the inductively coupled plasma (ICP) ionization source. (cdc.gov)
  • The concentrations of 20 urinary metals were determined using inductively coupled plasma mass spectrometer. (bvsalud.org)
  • Tackle complexity with the Thermo Scientific Direct Mass Technology mode to provide insights into complex macromolecules by adding charge detection capabilities. (thermofisher.com)
  • Add on Direct Mass Technology mode for samples too complex to resolve by ensemble measurements for direct and accurate mass determination with charge detection. (thermofisher.com)
  • The major types of analytical instrumentation employed electromagnetic detection, electrochemical processes, chromatographic methods, mass spectrometry, or automated wet chemistry. (cdc.gov)
  • Electron impact has remained the most widely used method of ionization in mass spectrometry. (britannica.com)
  • Without separation coupling, the basic building blocks in MMS, which are similar in composition with the conventional laboratory counterpart, are sample inlet, ionization source, mass analyzers, detector, vacuum system, instrument control and data acquisition system. (wikipedia.org)
  • For the first time, the new Desorption Electrospray Ionization DESI XS source is available on the Waters SELECT SERIES Cyclic IMS, SYNAPT™ XS, and Xevo™ G2-XS QTof Mass Spectrometers. (technologynetworks.com)
  • As a direct ionization source, DESI XS eliminates the need for sample preparation and chromatography prior to the introduction of the sample into the mass spectrometer, saving scientists time, lab space and expense. (technologynetworks.com)
  • A paper spray ionization mass spectrometry (PSI-MS) was developed to detect and quantify bisphenol S in three different brands of thermal papers commercially available. (springer.com)
  • Chen S, Chang Q, Yin K, He Q, Deng Y, Chen B, Liu C, Wang Y, Wang L (2017) Rapid analysis of bisphenol a and its analogues in food packaging products by paper spray ionization mass spectrometry. (springer.com)
  • Identification to species level of live single microalgal cells from plankton samples with matrix-free laser/desorption ionization mass spectrometry. (mpg.de)
  • Live single-cell metabolomics with matrix-free laser/desorption ionization mass spectrometry to address microalgal physiology. (mpg.de)
  • This strategy has been successfully from large groupings of organisms, electrospray ionization used with consensus 16S ribosomal RNA primers for deter- mass spectrometry for accurate mass measurements of PCR products, and base composition signature analysis to mining bacterial diversity, both in environmental samples identify organisms in a sample. (cdc.gov)
  • The first section examines who uses mass spectrometers, followed by how compounds are ionized in the source to be analyzed by mass spectrometers. (selectscience.net)
  • A description of the various types of mass spectrometers is followed by a discussion of the important topics of mass accuracy and resolution - or how well we can tell differences between closely related compounds. (selectscience.net)
  • The text provides practical approaches to interpreting mass spectral data and step-by-step guides for identifying chemically relevant compounds. (wordtrade.com)
  • We use gas chromatography (GC) to resolve complex mixtures of gases, and volatile and semi-volatile compounds, coupled with mass spectrometry (GC-MS) and other detectors such as flame ionisation (FID) and electron capture (ECD). (ncl.ac.uk)
  • Routine work includes determination of molecular formula and accurate mass with an accuracy of ± 1 mDa of compounds with m/z up to 3000 mDa. (lu.se)
  • This in situ analysis can lead to much simpler mass spectrometer operation such that non-technical personnel like physicians at the bedside, firefighters in a burning factory, food safety inspectors in a warehouse, or airport security at airport checkpoints, etc. can analyze samples themselves saving the time, effort, and cost of having the sample run by a trained MS technician offsite. (wikipedia.org)
  • Sample preparation including sample collection, extraction, pre-separation increases the size of the mass analysis system and adds time and sophistication to the analysis. (wikipedia.org)
  • Ultra-high mass quadrupole selection up to 25k m/z and higher fragmentation efficiency in the injection flatapole and HCD cell region allow native top-down analysis. (thermofisher.com)
  • Responsible for training work including basic knowledge and principle of mass spectrometry, sample preparation, data analysis, etc. (nature.com)
  • Familiarity with use, maintenance and development of LTQ Orbitrap Velos, Q Exactive and other large-scale bio-mass spectrometer, providing high-quality MS analysis Services to other laboratories at HCLS. (nature.com)
  • The Thermo Scientific ARL iSpark Plus Optical Emission Spectrometer range is designed to streamline elemental analysis in the metal production, processing and recycling industries, as well as in contract and research labs. (labonline.com.au)
  • In this application note, Shimadzu demonstrates the capability of its imaging platform to easily achieve quality mass spectra and MS images for intact proteins from tissue sections and for peptides following on-tissue digestion, with linear mode analysis of rat brain tissue. (selectscience.net)
  • The ability to integrate qualitative and quantitative analysis within a single platform enables new and better ways to think about conducting experiments," notes Gerard Hopfgartner, Ph.D., professor and scientist, University of Geneva's Mass Spectrometry Centre. (genengnews.com)
  • This unique reference makes some of the esoteric aspects of this important area of analysis more readily comprehensible to those who deal with analytical instruments but who have not been trained in mass spectrometry. (wordtrade.com)
  • Maximize product yield and increase profitability with process mass spectrometry analysis. (azocleantech.com)
  • Monitoring CPPs with process mass spectrometry gas analysis reduces over-processing, pinpoints contaminants, and increase product consistency. (azocleantech.com)
  • All of the gas components are analyzed within a single scan and the results of the analysis are displayed as a mass spectrum (plot of m/e versus peak intensity). (mks.com)
  • In this guidebook, we will introduce polymeric material analysis solutions that make full use of JEOL's high-performance mass spectrometers. (jeolusa.com)
  • A new software program was recently reported that integrates all of the available mass spectrometric information from GC-HRTOFMS analysis into a concise report. (jeolusa.com)
  • The environmental mass spectrometry laboratory has over 30 years of experience in the analysis of soil and sediments, and gas samples. (ncl.ac.uk)
  • The environmental mass spectrometry laboratory can perform both routine and bespoke GC and GC-MS analysis with integrated liquid and pyrolysis autosamplers, and gas sampling valves. (ncl.ac.uk)
  • Castro G, Rodríguez I, Ramil M, Cela R (2019) Direct analysis in real time accurate mass spectrometry determination of bisphenol A in thermal printing paper. (springer.com)
  • The oral sessions, held from June 2 through June 5, covered such topics as label-free quantitation of proteins, using MSfor elemental analysis, discovering peptide biomarkers, MS characterization of carbohydrates, pharmaceutical drugs as environmental pollutants, and the role of mass spectrometry in the petroleum field. (chromatographyonline.com)
  • Once ionized, the volatiles are pulled into the mass spectrometer for analysis (4). (jove.com)
  • In principle, the electromagnetic field mainly depends on the shape of the mass analyzers. (wikipedia.org)
  • Some researchers are successful in designing a series of miniature TOF mass analyzers. (wikipedia.org)
  • These include mass-spectrometers, gas analyzers, and fluorescence/Raman spectrometry instruments. (nasa.gov)
  • MKS's RGA product line offers a variety of levels of RGA utility, from simple partial pressure analyzers to complex mass spectrometers. (mks.com)
  • This webinar highlights the needs and versatility of ultrahigh-resolution mass spectrometers for heightened mAb characterization in Pfizer's MSBC lab, as well as addresses the importance of different separation techniques coupled to Mass Spectrometry. (news-medical.net)
  • Mass spectrometry is utilized in a multitude of fields ranging from medical characterization of proteins 4 to detecting pesticide amounts in foods and dietary supplements 5 . (noaa.gov)
  • KBI's state-of-the-art mass spectrometry core facility delivers unparalleled structural characterization services to our clients. (kbibiopharma.com)
  • In support of biotherapeutics across the board, KBI's Mass Spectrometry Core Facility has championed the characterization and management of proteins, active pharmaceutical ingredients (APIs), and impurities through identification, characterization, assessment, and quantitation. (kbibiopharma.com)
  • We recently sat down with Michael J. Nold, Ph.D., Senior Director of KBI's Mass Spectrometry Core Facility in Durham, North Carolina, to discuss how advanced Mass Spectrometry plays a significant analytical role in the characterization and quantitation of APIs and impurities in complex biotherapeutics. (kbibiopharma.com)
  • Advanced analytical capabilities, including mass spectrometry, are critical for the characterization of active pharmaceutical ingredients (APIs) and managing a diverse population of impurities. (kbibiopharma.com)
  • 2017. Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry. . (oregonstate.edu)
  • In typical mass spectrometry, MS is coupled with separation tools like gas chromatography, liquid chromatography or electrophoresis to reduce the effect of the matrix or background and improve the selectivity especially when the analytes are widely different in concentration. (wikipedia.org)
  • The PSI-MS method described here was comparable to the conventional ones, such as liquid chromatography coupled with mass spectrometry and gas chromatography coupled with mass spectrometry described in the literature. (springer.com)
  • AB Sciex is working with the University of Geneva's Mass Spectrometry Centre to create new workflows and analytical strategies that improve drug discovery and development. (genengnews.com)
  • Mass Spectrometry Basics by Christopher G. Herbert, R. A. W. Johnstone (CRC Press) Provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. (wordtrade.com)
  • ECD is an electron-based fragmentation technology that, combined with ion mobility mass spectrometry and Collision Induced Dissociation (CID) available with the Cyclic IMS System, gives scientists improved sequence coverage for native proteins and surrogate peptides and additional structural information about larger proteins that might not have been possible before. (technologynetworks.com)
  • The versatile Waters™ Cyclic IMS System is the only ion mobility time-of-flight mass spectrometer to perform scalable ion mobility separations and that is also capable of IMSn experiments (e.g. selecting an ion by IMS, fragmenting the ion, selecting a particular fragment by IMS and repeating the process) which derives detailed structural information about a single analyte. (technologynetworks.com)
  • Mass spectrometry studies benefit heavily from our Waters Synapt ion mobility mass spectrometer. (cardiff.ac.uk)
  • We operate condensation particle counters for total number particle concentration, scanning mobility particle sizers for precision measurements of particle size distributions, and a fast mobility spectrometer which produces highly time-resolved size measurements (1 Hz). (lu.se)
  • Several methods based on mass spectrometry have been developed to analyse the metabolome in blood and urine samples (polyphenols, sex steroids, and intermediate metabolism). (who.int)
  • Methods Vȯ 2 was measured simultaneously and continuously for 10 minutes by using respiratory mass spectrometry and the breath-by-breath method in children receiving mechanical ventilation via cuffed endotracheal tubes. (medscape.com)
  • Therefore, the most widely used research tool to measure Vȯ 2 in critically ill children, especially after cardiac surgery, has been the respiratory mass spectrometer (Amis 2000, Innovision ApS), but it is no longer manufactured. (medscape.com)
  • The success of a PMF experiment depends on several factors: The noise level in the spectrum, the mass accuracy, the amount and purity of the sample, the number of proteins in the sample, possible post-translational modifications, algorithm accuracy, and (to a considerable extent) operator skill and experience. (lu.se)
  • The vapors are introduced to a mass spectrometer, which enables highly time and size resolved (10 Hz) measurements of particle chemical composition. (lu.se)
  • Objective To compare measurements of Vȯ 2 using respiratory mass spectrometry and the breath-by-breath method. (medscape.com)
  • Conclusions Measurements of Vȯ 2 did not differ between mass spectrometry and the breath-by-breath method. (medscape.com)
  • Core facilities currently undergoing include: Cryo-Electron Microscopy Platform, Imaging Platform, Mass Spectrometry Platform, Nuclear Magnetic Technology Platform, SPF Laboratory Animal Room. (nature.com)
  • The laboratory also has LC-MS systems and a thermogravimetric analyser interfaced to a mass spectrometer (TGA-MS). (ncl.ac.uk)
  • Increasingly, tandem mass spectrometry (MS/MS) is being used for newborn screening because this laboratory testing technology substantially increases the number of metabolic disorders that can be detected from dried blood-spot specimens. (cdc.gov)
  • researchers, the relocation of the BMA laboratory and offices to the tower building with a larger space, and the acquisition of two new mass spectrometers and a robot for sample handling. (who.int)
  • The ultra-high mass selection quadrupole can be used to isolate the 4 MDa HBV particle at m/z 25,000 for subsequent fragmentation. (thermofisher.com)
  • A novel methodology was introduced to investigate differences in soot maturity using a soot particle aerosol mass spectrometer (SP AMS). (lu.se)
  • This approach is known as peptide mass fingerprinting (PMF) [1-4]. (lu.se)
  • An Agilent 6550 QTOF mass spectrometer was installed in January, 2013. (bu.edu)
  • We are a service facility equipped with unique technology and experienced scientists in the field of mass spectrometry. (lu.se)
  • idea, the omegatron and the Fourier-transform spectrometer. (britannica.com)
  • Parameters such as paper size, and paper position relative to the mass spectrometer inlet were evaluated. (springer.com)
  • Quantitative analyses can be obtained for most elements in the mass range 5-250 amu (practically 7 Li to 238 U). (lu.se)
  • Understanding the biology of disease and discovering new treatments requires us to continue innovating new and powerful capabilities for mass spectrometry so that scientists can accurately and confidently answer their scientific questions. (technologynetworks.com)
  • The Mass Spectrometry Primer, an 82-page paperback book, covers a wide range of topics related to the most wide spread of modern mass spectrometry practices and answers some frequently asked questions about the use and capabilities of mass spectrometers. (selectscience.net)
  • Postdoctoral training or experience working in mass spectrum management is highly preferred. (nature.com)
  • Mass Spectrometry Basics describes processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. (wordtrade.com)
  • When coupled to a mass spectrometer, DESI XS produces a visual map of the spatial distribution of small molecule drugs, metabolites and lipids within a variety of sample and surface types. (technologynetworks.com)
  • In this spectrometer the sample is subjected to a broadband source of radiation, resulting in the production of an interferogram due to the absorption of specific components of the radiation. (britannica.com)
  • HTX Imaging's patented TM-Sprayer™ Tissue MALDI Sample Preparation System is designed to provide the highest quality matrix deposition on the two-dimensional biological samples, and can be integrated with any MALDI Mass Spectrometer platform. (boisestate.edu)
  • Furthermore, because all species within a given sample are analyzed, mass spectrometers can detect and highlight the presence of unexpected species or contaminants in a product gas stream. (mks.com)
  • This method directly measures the iodine of urine specimens using mass spectrometry after a simple dilution sample preparation step. (cdc.gov)
  • Choose the appropriate vessel for growing your cultures, considering the growth requirements of the species in your experiment (e.g., aeration, light, temperature, etc.), as well as the efficient delivery of volatiles to the mass spectrometer. (jove.com)
  • MKS, Granville-Phillips offers the 835 Vacuum Quality Monitor (VQM ® ) mass spectrometer for the measurement of partial pressures in vacuum systems. (mks.com)
  • NMR work is performed using our flagship 600 MHz Bruker NMR spectrometer equipped with a quadruple resonance QCI cryoprobe, as well as national high-field NMR facilities. (cardiff.ac.uk)
  • Bruker Q-TOF Mass Spectrometer is located in the mass spectrometer is located in the BRC, room 215 in the Mathematics Building on the campus of Boise State University. (boisestate.edu)