Mass and fragment. Medical search. Frequent questions

Cross-linking technology combined with tandem mass spectrometry (MS-MS) is a powerful method that provides a rapid solution to the discovery of protein-protein interactions and protein structures. (nih.gov)
This study aimed to establish a method to simultaneously quantify 11 CYP isoforms by multiplexed-multiple reaction monitoring analysis with liquid chromatography tandem mass spectrometry and in silico peptide selection to clarify CYP isoform expression profiles in human liver tissue. (nih.gov)
Quantification of glyphosate and other organophosphorus compounds in human urine via ion chromatography isotope dilution tandem mass spectrometry. (cdc.gov)
The procedure involves enzymatic hydrolysis of urine, extraction, derivatization, and column cleanup, followed by analysis of the concentrate using capillary gas chromatography combined with tandem mass spectrometry (GC-MS/MS). This procedure uses isotope dilution with 13 C-labeled internal standards for all analytes. (cdc.gov)
Characterization of diisocyanate haptenation of serum albumin by multiplexed tandem mass spectrometry. (cdc.gov)
The studies presented here have applied modern analytical proteomics methodologies (in particular, multiplexed tandem mass spectrometry) to characterize the conjugation chemistry of industrially relevant diisocyanate s on model proteins. (cdc.gov)

Here, we used mass spectrometry (MS)-based methods to determine and quantify, in a time-dependent manner, early molecular events triggered following TCR stimulation with peptides of varying affinities. (nature.com)
Unlike other analytical tools such as circular dichroism, dynamic light scattering, or mass spectrometry, fluorescence spectroscopy can readily probe heterogeneous samples such as agarose beads. (nature.com)
Mass spectrometry (MS) is a powerful technique for the characterization of isomeric compounds. (unica.it)
Cell proteins were analysed with 2-dimensional electrophoresis and differentially expressed proteins were identified by matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry. (who.int)
Mass spectrometry combined with database searching is today the preferred method for protein identification. (lu.se)

1] In a previous study, it was demonstrated that CID experiments on the [M + 103]+ adduct ions, using a quadruple ion-trap mass spectrometer, was effective for the differentiation of isomeric naturally-occurring phenols. (unica.it)
2] However, the fragmentation behaviour of the [M + 25]+ fragment ions was not investigated. (unica.it)
This study illustrates the effectiveness of CI (α-PVC) for isomer differentiation based on the CID mass spectra of the [M + 25]+ fragment ions. (unica.it)
During analysis, the analytes dissociate into charged fragments (ions) that are specific to each analyte. (cdc.gov)
CID produces sequence-informative fragmentation and unambiguous determination of the conjugation site is possible on the basis of mass shifts of resultant fragment ions. (cdc.gov)
In these experiments, CID is performed in a multiplexed manner (e.g. alternating low and high collision energy scans) to allow high mass accuracy scans of parent and daughter fragment ions that may be temporally correlated in silico post run. (cdc.gov)

Whether you are performing your first cloning experiment or constructing multi-fragment DNA assemblies, NEB ® has the solution for you. (neb.com)

Restriction Fragment Mass Polymorphism (RFMP) is a technology which digests DNA into oligonucleotide fragments, and detects variation of DNA sequences by molecular weight of the fragments. (wikipedia.org)
Restriction fragment mass polymorphism (RFMP) is an application of matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF), used for identifying individual nucleotides from a DNA fragment, most commonly used in labeling single nucleotide polymorphisms (SNP). (wikipedia.org)
RFMP was developed as a successor to the similar restriction fragment length polymorphism (RFLP) with the intent to allow for more SNPs. (wikipedia.org)
A total of 10,883 isolates were fingerprinted by the IS 6110 -restriction fragment length polymorphism method, yielding 6,128 distinct patterns. (cdc.gov)

Rather than read out lengths of fragments as RFLP does, the individual nucleotides are read out using MALDI-TOF, which gives specific clarity over same-length site cutting. (wikipedia.org)

Major Archbishop Sviatoslav Shevchuk gave Pope Francis a fragment from a Russian mine that destroyed the front of a church in Irpin, Ukraine, in March 2022. (catholicnewsagency.com)
OUR Bakery / studio fragment" 27 Jul 2022. (archdaily.com)

The site(s) of diisocyanate conjugation upon the model protein(s) are characterized by enzymatic digestion of the conjugated protein, followed by fragmentation of the resultant enzymatic peptides by collision-induced dissociation (CID) in a quadrupole time-offlight (qTOF) mass spectrometer. (cdc.gov)
The standard experiment is to separate the proteins, e.g. by 2D gel electrophoresis, digest the proteins with a highly specific enzyme, measure the masses of the peptide fragments with a mass spectrometer (typically a MALDI-TOF mass spectrometer) and then compare the peptide monoisotopic masses with expected monoisotopic masses from a database (protein or DNA database). (lu.se)
We image ionic fragments in a multicoincidence time-of-flight spectrometer. (lu.se)

Finally, MALDI-TOF is run on the fragments of interest to produce a m/z (mass-to-charge ratio) identification spectra of the individual nucleotides. (wikipedia.org)
An interchain cross-link between two beta subunits was found in two tandem mass spectra. (nih.gov)
The strategy is compared against both manual peak picking and industry standard automated peak picking on a set of mass spectra obtained after tryptic in gel digestion of 2D-gel samples from human fetal fibroblasts. (lu.se)

Strands of either length are put under MALDI-TOF mass spectroscopy, to determine the individual nucleotides. (wikipedia.org)

In more severe cases, the bone may be broken into several fragments, known as a comminuted fracture . (wikipedia.org)

The project involves analysis of data obtained at MAX-Lab and includes interpretation of the alignment of core-excited molecules based upon the quantum mechanical dipole operator, as well as analysis of the three-dimensional momentum of fragments from single dissociation events in order to extract information about the geometry and the final dissociative states. (lu.se)

Therefore, it is vital to study the impact of blasting stress waves on the surrounding rock mass as well as the process of rock damage and the mechanism of fragmentation. (hindawi.com)
The test results showed that the fragments produced by rock fragmentation under impact load have fractal characteristics. (hindawi.com)

Shape-dependent microscopic level densities are used to guide the random walk, to partition the intrinsic excitation energy between the two proto-fragments at scission, and to determine the number of neutrons evaporated from the fragments. (lu.se)
The contribution to the total excitation energy of the resulting fragments from. (lu.se)
The contribution to the total excitation energy of the resulting fragments from statistical excitation and shape distortion at scission is studied. (lu.se)

The emission probability of Intermediate Mass Fragments (IMFs) in non-central reactions has been investigated in collisions of heavy 124Xe projectiles with the two different medium-mass targets of 64Ni and 64Zn at the laboratory energy of 35 A MeV. (unict.it)
The probability of IMFs emission from the projectile-like fragment has been measured, showing an enhancement of the IMFs emission for the neutron rich 64Ni target. (unict.it)

The concentrate is analyzed using liquid chromatography combined with tandem mass spectrometric (LC/MS/MS) determination. (cdc.gov)

I saw bodies and body fragments on the floor. (pravda.ru)
Tidal disruption of a monolithic asteroid creates large km-size fragments, and only parent bodies ≥100 km are able to generate enough fragments for mutual collisions to be significant. (lu.se)

We identify fragment hits and obtain X-ray complex structures for three fragments via crystal soaking using a new crystal form of KEAP1. (rcsb.org)

As the new year gets underway, PepsiCo Beverages is ramping up its video marketing efforts to better reach shoppers across an increasingly fragmented landscape. (digiday.com)
The competition has made for a fragmented media landscape, challenging brands like PepsiCo to find the most cost-effective way to capture and keep consumers' attention. (digiday.com)

He also noted that the gnostic gospel genre to which the fragment evidently belongs is one of stories about Jesus that mainly take place after the resurrection, using language that is heavily allegorical. (catholicfreepress.org)

It does not, however, provide evidence that the historical Jesus was married," she wrote, "given the late date of the fragment and the probable date of original composition," at the end of the second century. (catholicfreepress.org)
La présente étude visait à identifier le(s) vecteur(s), le parasite et la composition des espèces des phlébotomes dans le district, de juillet à septembre 2009, à l'aide de techniques d'amplification en chaîne par polymérase. (who.int)

Evolutionary science, spine-tingling horror and reality television collide in Warren Fahy's FRAGMENT, a terrific debut novel that illustrates how scientists' dream discovery quickly devolves into their worst nightmare on the world's most secluded island. (bookreporter.com)

and the second step finds the best cross-linked amino acids in these two peptide sequences that are optimally correlated to a given tandem mass spectrum. (nih.gov)
The strategy therefore promises reliable automated user- independent protein identification using peptide mass fingerprints. (lu.se)
This approach is known as peptide mass fingerprinting (PMF) [1-4]. (lu.se)

FRAGMENTS is a projection-mapped piece inspired by geometric patterns and shapes. (gold.ac.uk)
Although FRAGMENTS doesn't have a linear narrative, the shape is constantly filled with moving lines evolving to different coloured patterns. (gold.ac.uk)
The future directions of this research project goes towards stacked growth of other 2D materials as for example 2D transition metal disulfides and the growth from mass selected and charged fragments onto imprinted charge or defect patterns on 2D films. (lu.se)

Serashi Fragments was first performed by the Arditti Quartet (Irvine Arditti, Ashot Sarkissjan, Ralf Ehlers, Lucas Fels) on April 2nd, 2006 in Paine Hall, Cambridge MA. (eamdc.com)

The analysis suggests influence of the target isospin in inducing the dynamical break-up of projectile-like fragments. (unict.it)
Alien-hunting Harvard physicist Professor Avi Loeb said early analysis of metal fragments his team recovered from the Pacific Ocean in June suggests they came from interstellar space. (dailymail.co.uk)
The data from the analysis showed that the fragments are rich in Beryllium, lanthanum and uranium, along with low content of elements with high affinity to iron, like Rhenium. (dailymail.co.uk)
Analysis of the fragments showed they are rich in Beryllium, lanthanum and uranium, along with low content of elements that bind to iron, like Rhenium - one of the rarest elements found on Earth. (dailymail.co.uk)

Scope and Contents This collection documents the history of forty-seven charitable societies that were in existence throughout Massachusetts in the nineteenth century. (bpl.org)

However, the main purpose of sampling is the same-to be able to extract a small mass of the target lot that is to be characterised (analysed), i.e. to obtain a sample, which accurately and precisely represents the lot (see definition below). (spectroscopyeurope.com)
Collagen's rubbery consistency allows bone fragments to move only a small amount unless severe or persistent force is applied. (wikipedia.org)

The success of a PMF experiment depends on several factors: The noise level in the spectrum, the mass accuracy, the amount and purity of the sample, the number of proteins in the sample, possible post-translational modifications, algorithm accuracy, and (to a considerable extent) operator skill and experience. (lu.se)

Priority pesticides (non-persistent pesticide metabolites) were measured using two mass spectrometric methods. (cdc.gov)

Good agreement is obtained with available experimental data on neutron multiplicities in correlation with fission fragments from U235(nth,f). (lu.se)

Urinary organophosphate pesticides uses azeotropic codistillation of urine, derivitization, gas chromatography-tandem mass spectrometric method (GC-MS/MS). This method can be used to quantify the six dialkylphosphate human metabolites of organophosphate pesticides in urine. (cdc.gov)

Here, we describe the combined application of alanine-scanning mutagenesis, fragment screening, and FTMap computational hot spot mapping to evaluate the energetics and druggability of the highly charged PPI interface between Kelch-like ECH-associated protein 1 (KEAP1) and nuclear factor erythroid 2 like 2 (Nrf2), an important drug target. (rcsb.org)

Accumulation of floating ice made up of fragments not more than 2 m across, the wreckage of other forms of ice. (canada.ca)

We studied the problem of detecting cross-linked peptides and cross-linked amino acids from tandem mass spectral data. (nih.gov)

The results showed that the absorbed energy per unit volume and the crushing energy per unit mass of dolomite marble are closely related to the dynamic compressive strength. (hindawi.com)
We calculate neutron multiplicities from fission fragments with specified mass numbers for events having a specified total fragment kinetic energy. (lu.se)
With increasing neutron energy a superlong fission mode grows increasingly prominent, which affects the dependence of the observables on the total fragment kinetic energy. (lu.se)

Continental crustal fragments , partly synonymous with microcontinents , [1] are pieces of continents that have broken off from main continental masses to form distinct islands that are often several hundred kilometers from their place of origin. (wikipedia.org)

But the tiny papyrus fragment, purportedly dating to the fourth century A.D., has already stirred interest in the early church's attitudes toward marriage, sex and the role of women. (catholicfreepress.org)

In many cases, efforts overlap, results are fragmented, and activities do not align with country priorities and capacities. (who.int)

Home Tools & Resources Video Library Quick Tips - How can I efficiently elute large DNA fragments from agarose gels? (neb.com)
This video gives tips on eluting large DNA fragments from agarose gels. (neb.com)

However, in some patients, the physicochemical characteristics of the immunoglobulin L chain or L-chain fragment lead to its deposition as amyloid. (medscape.com)

At relative velocities of tens of km s-1, such collisions grind down the tidal fragments into smaller and smaller dust grains. (lu.se)

A human operator is generally better than software algorithms at judging what is an interesting low intensity monoisotopic peak, as opposed to a noise peak, and what is a reasonable identity given mass deviations and sequence coverage. (lu.se)

King said that the significance of the fragment lies in the light it might shed on debates in the early church over the necessity of celibacy to living a holy life. (catholicfreepress.org)
In nearly all cases, the deposits contain immunoglobulin light (L) chains or L-chain fragments, termed L chain-type amyloidosis (AL). (medscape.com)
Before the discovery that the major fibril component in these patients was an immunoglobulin fragment, patients with light chain-type amyloidosis were described as having primary amyloidosis (primary in the sense of idiopathic) or, when the burden of monoclonal plasma cells was large, myeloma-associated amyloidosis. (medscape.com)

The blood coagulates to form a blood clot situated between the broken fragments. (wikipedia.org)

FRAGMENT opens in 1791, as a ship on the trail of mutineers from the HMS Bounty happens upon a forbidding walled island in the most isolated region of the vast South Pacific Ocean. (bookreporter.com)
Because the sequential depositing of potsherds (fragments of pottery) in an easterly direction across the island groups of the Pacific has become the pivotal evidence that tells the extraordinary story of the peopling of the vast Pacific Ocean. (khanacademy.org)

Anatomy13

Organisms12

Diseases3

Chemicals and Drugs85

Analytical, Diagnostic and Therapeutic Techniques and Equipment61

Phenomena and Processes93

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena2

Information Science8

Health Care7

Tandem mass spectro6

Spectrometry5

Ions6

Multi-fragment1

Polymorphism4

RFLP1

20222

Spectrometer3

Spectra3

MALDI-TOF1

Fracture1

Dissociation1

Fragmentation2

Excitation3

Probability2

Liquid chromatography1

Bodies2

Structures1

Landscape2

Belongs1

Composition2

Illustrates1

Peptide3

Patterns3

Cambridge1

Analysis4

Existence1

Small2

Spectrum1

Methods1

Experimental1

Method1

Protein1

Made1

Data1

Energy3

Main1

Tiny1

Results1

Video2

Lead1

Smaller1

Algorithms1

Light3

Broken1

Island2