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  • Aplastic Anemia
  • Purpose: This phase I/II trial is to evaluate the safety and efficacy of fludarabine, cyclophosphamide and antithymocyte globulin with CD3±CD19 depleted graft from haploidentical donors in treating patients with aplastic anemia. (clinicaltrials.gov)
  • hematopoietic cell
  • In a previously reported international prospective study based on treatment allocation by genetic chance, we provided evidence that, among children with acute lymphoblastic leukemia, the 8% carrying very high risk characteristics and achieving first complete remission benefit from hematopoietic cell transplant from a compatible related donor ( Table 1 ). (haematologica.org)
  • grafts
  • We previously reported early results of a clinical trial using ex vivo induction of alloanergy in donor T cells within bone marrow (BM) grafts via CTLA4-Ig-mediated CSB. (bloodjournal.org)
  • NMDP
  • BMT CTN is funded through the National Institutes of Health (NIH) and is a collaborative effort of the CIBMTR at the Medical College of Wisconsin, the National Marrow Donor Program (NMDP), and the EMMES Corporation, together with 20 Core Transplant Centers/Consortia. (healthcanal.com)