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  • bone marrow
  • Explain to women that the presence of bone marrow micrometastases may help determine effective treatment options. (medpagetoday.com)
  • INNSBRUCK, Austria, Aug. 25-The presence of bone marrow micrometastases in women newly diagnosed with breast cancer is a highly significant predictor of poor outcome, according to a pooled analysis of data from nine breast cancer studies. (medpagetoday.com)
  • Bone marrow examination refers to the pathologic analysis of samples of bone marrow obtained by bone marrow biopsy (often called a trephine biopsy) and bone marrow aspiration. (wikipedia.org)
  • The bone marrow produces the cellular elements of the blood, including platelets, red blood cells and white blood cells. (wikipedia.org)
  • this is the role of bone marrow aspiration and biopsy. (wikipedia.org)
  • Bone marrow samples can be obtained by aspiration and trephine biopsy. (wikipedia.org)
  • Sometimes, a bone marrow examination will include both an aspirate and a biopsy. (wikipedia.org)
  • The aspirate yields semi-liquid bone marrow, which can be examined by a pathologist under a light microscope and analyzed by flow cytometry, chromosome analysis, or polymerase chain reaction (PCR). (wikipedia.org)
  • Frequently, a trephine biopsy is also obtained, which yields a narrow, cylindrically shaped solid piece of bone marrow, 2mm wide and 2 cm long (80 μL), which is examined microscopically (sometimes with the aid of immunohistochemistry) for cellularity and infiltrative processes. (wikipedia.org)
  • An aspiration, using a 20 mL syringe, yields approximately 300 μL of bone marrow. (wikipedia.org)
  • Bone marrow aspiration and trephine biopsy are usually performed on the back of the hipbone, or posterior iliac crest. (wikipedia.org)
  • Bone marrow aspiration may also be performed on the tibial (shinbone) site in children up to 2 years of age while spinous process aspiration is frequently done in a lumbar puncture position and on the L3-L4 vertebrae. (wikipedia.org)
  • A bone marrow biopsy may be done in a health care provider's office or in a hospital. (wikipedia.org)
  • Once the needle is in the marrow cavity, a syringe is attached and used to aspirate ("suck out") liquid bone marrow. (wikipedia.org)
  • The needle is then advanced with a twisting motion and rotated to obtain a solid piece of bone marrow. (wikipedia.org)
  • There are few contraindications to bone marrow examination. (wikipedia.org)
  • human bone marrow
  • The chapter examines pathologic findings seen in the human bone marrow. (springer.com)
  • In-vitro colony forming cell (CFC) assays using normal human bone marrow grown in appropriate semi-solid media such as ColonyGEL have been shown to be useful in predicting the level of clinical myelotoxicity a certain compound might cause if administered to humans. (wikipedia.org)
  • donor
  • Jul 18, 2016 - In this profound and ultimately uplifting memoir, Omega Institute cofounder Lesser (Broken Open) shares the experience of becoming her younger sister's bone-marrow donor after the sister's recurrence of stage-IV mantle-cell lymphoma. (apple.com)
  • Each day a bone marrow donor recruitment clinic will be held, where you will have the opportunity to join the bone marrow register. (warwick.ac.uk)
  • Thomas adopted methods to match the tissues of donor and recipient closely enough to minimize the latter's rejection of the former's marrow. (britannica.com)
  • progenitor cells
  • These predictive in-vitro assays reveal effects the administered compounds have on the bone marrow progenitor cells that produce the various mature cells in the blood and can be used to test the effects of single drugs or the effects of drugs administered in combination with others. (wikipedia.org)
  • zucchini
  • Marrows, like zucchini, are low in food energy (approximately 71 kJ or 17 kcal per 100 g fresh marrow) and contain useful amounts of folate (24 μg/100 g), potassium (261 mg/100 g) and provitamin A (200 IU [10 RAE]/100 g). (wikipedia.org)
  • Members of the plant family Cucurbitacea, which includes zucchini, marrows, pumpkins and cucumbers, can contain toxins called cucurbitacins. (wikipedia.org)
  • 1990
  • In 1990 Thomas was corecipient (with American surgeon Joseph E. Murray ) of the Nobel Prize for Physiology or Medicine for his pioneering work on bone marrow transplantation. (britannica.com)
  • thrombocytes
  • Bone marrow suppression also known as myelotoxicity or myelosuppression, is the decrease in production of cells responsible for providing immunity (leukocytes), carrying oxygen (erythrocytes), and/or those responsible for normal blood clotting (thrombocytes). (wikipedia.org)
  • immature
  • The necessity for a bone marrow aspiration is ordinarily based on previous blood studies and is particularly useful in providing information on various stages of immature blood cells. (britannica.com)
  • Diseases of the bone marrow may lead to an abnormality in the production of any of the mature blood cells, or their precurosor or predecessor immature cells. (news-medical.net)
  • Blood picture shows immature cells from the bone marrow called blast cells. (news-medical.net)
  • There is overproduction of a precursor (immature form) of a marrow cell. (news-medical.net)
  • Before the introduction of Cucurbita species from the New World, marrow signified the immature, edible fruits of Lagenaria, a cucurbit gourd of African origin widely grown since Antiquity for eating when immature and for drying as watertight receptacles when grown to maturity. (wikipedia.org)
  • However, both in North America (since the 1920s) and in Britain (since the 1960s), thinner-skinned immature marrows have gained popularity due to their tender skin, firmer texture and distinct flavour. (wikipedia.org)
  • The fashion for eating immature marrows, called in Britain "courgettes", is relatively recent in Britain. (wikipedia.org)
  • 1718
  • As a consequence of this conversation, in 1718 arrangements were made to have the Marrow reprinted, with a preface by James Hog of Carnock. (wikipedia.org)
  • disorders
  • Bone marrow failure syndromes are relatively rare and universally complex disorders. (childrens.com)
  • The Bone Marrow Failure Program at the Gill Center has the breadth and depth of expertise needed to provide complete care to children and their families affected by these hematologic disorders. (childrens.com)
  • 1994
  • She made progress controlling her powers and learning a moral code, but eventually fell in with the paramilitary group Weapon X. As a child, Marrow first appeared in Cable #15 (September 1994) and was created by writer Jeph Loeb and artist David Brewer. (wikipedia.org)
  • Marrow first appeared in Cable #15 (September 1994) and was created by writer Jeph Loeb and artist David Brewer. (wikipedia.org)
  • 1971: Newport News, Virginia 1972: Sister Woman 1994: Queen Esther Marrow & the Harlem Gospel Singers 1999: Live in Paris 2000: Harlem Gospel Singers with Queen Esther Marrow 2002: God Cares Paula Span (1999-01-31). (wikipedia.org)
  • myeloid
  • Topics covered include myeloid neoplasms of the bone marrow, including both chronic and acute myeloid leukemias. (springer.com)
  • Dunphy CH, O'Malley DP, Perkins SL, Chang CC. Analysis of immunohistochemical markers in bone marrow sections to evaluate for myelodysplastic syndromes and acute myeloid leukemias. (springer.com)
  • biopsy
  • this is the role of bone marrow aspiration and biopsy. (wikipedia.org)
  • Bone marrow samples can be obtained by aspiration and trephine biopsy. (wikipedia.org)
  • Frequently, a trephine biopsy is also obtained, which yields a narrow, cylindrically shaped solid piece of bone marrow, 2mm wide and 2 cm long (80 μL), which is examined microscopically (sometimes with the aid of immunohistochemistry) for cellularity and infiltrative processes. (wikipedia.org)
  • Bone marrow aspiration and trephine biopsy are usually performed on the back of the hipbone, or posterior iliac crest. (wikipedia.org)
  • A bone marrow biopsy may be done in a health care provider's office or in a hospital. (wikipedia.org)
  • Bone marrow biopsy: interpretive guidelines for the surgical pathologist. (springer.com)
  • Morice WG, Kurtin PJ, Hodnefield JM, Shanafelt TD, Hoyer JD, Remstein ED, Hanson CA. Predictive value of blood and bone marrow flow cytometry in B-cell lymphoma classification: comparative analysis of flow cytometry and tissue biopsy in 252 patients. (springer.com)
  • This is called bone marrow aspiration or bone marrow biopsy. (news-medical.net)
  • transplants
  • Bone marrow suppression due to azathioprine can be treated by changing to another medication such as mycophenolate mofetil (for organ transplants) or other disease-modifying drugs in rheumatoid arthritis or Crohn's disease. (wikipedia.org)
  • aspiration
  • Bone marrow aspiration , the direct removal of a small amount (about 1 ml) of bone marrow, is accomplished by suction through a hollow needle. (britannica.com)
  • An aspiration, using a 20 mL syringe, yields approximately 300 μL of bone marrow. (wikipedia.org)
  • Bone marrow aspiration may also be performed on the tibial (shinbone) site in children up to 2 years of age while spinous process aspiration is frequently done in a lumbar puncture position and on the L3-L4 vertebrae. (wikipedia.org)
  • Our physician attempted a Bone Marrow Aspiration 38220, but a sample could not be obtained. (aapc.com)
  • diseases
  • Examination of the bone marrow is helpful in diagnosing certain diseases, especially those related to blood and blood-forming organs, because it provides information on iron stores and blood production. (britannica.com)
  • MDS is a group of diseases where there is abnormal bone marrow cell production. (news-medical.net)
  • Parvovirus B19 inhibits erythropoiesis by lytically infecting RBC precursors in the bone marrow and is associated with a number of different diseases ranging from benign to severe. (wikipedia.org)
  • suck
  • Once the needle is in the marrow cavity, a syringe is attached and used to aspirate ("suck out") liquid bone marrow. (wikipedia.org)
  • Those times when I realize I am alone with myself and my thoughts I do take the time to suck the marrow out of it. (dictionary.com)
  • citation needed] In Iranian cuisine, lamb shanks are usually broken before cooking to allow diners to suck out and eat the marrow when the dish is served. (wikipedia.org)
  • mainly
  • However, towards the end of the season, Marrow was mainly used as a substitute, making only four appearances after his return. (wikipedia.org)
  • Crystal Palace
  • On 21 August 2010, Marrow signed for Crystal Palace on a six-month loan. (wikipedia.org)
  • Marrow made his first Crystal Palace appearance for a year, in a 2-1 loss against Blackpool on 21 January 2012. (wikipedia.org)
  • Marrow made four appearances for Preston before he returned to Crystal Palace. (wikipedia.org)
  • At the start of the 2012-13 season, Marrow joined Fleetwood Town on loan, though Crystal Palace website stated it will end in January. (wikipedia.org)
  • Marrow made his first start for Crystal Palace in two years, as they beat Charlton Athletic on 4 February 2013. (wikipedia.org)
  • anemia
  • Led by Zora R. Rogers, M.D., a nationally recognized expert in pediatric hematology, the program manages ongoing treatment plans for children with congenital and acquired bone marrow failure syndromes, including Diamond-Blackfan anemia, Fanconi anemia, Shwachman-Diamond syndrome, idiopathic aplastic anemia and others. (childrens.com)
  • A leading contributor to bone marrow failure disorder registries, including the International Fanconi Anemia Registry, Diamond-Blackfan Registry, Shwachman- Diamond Registry and North American Pediatric Aplastic Anemia Consortium (NAPAAC). (childrens.com)
  • In immunocompromised patients, B19 infection may persist for months, leading to chronic anemia with B19 viremia due to chronic marrow suppression. (wikipedia.org)
  • grown
  • Giant marrows are grown competitively in the United Kingdom where the term "marrow" is often restricted to the striped, thick-skinned cultivar. (wikipedia.org)
  • In August 2015, a 79-year-old German man and his wife ate a marrow grown by a neighbour. (wikipedia.org)
  • novel
  • Clause Lalumière viewed Marrow as essentially a world-building exercise unnaturally constrained into the novel form and would rather have seen a collection of short stories flesh out the world he'd created. (wikipedia.org)
  • needle
  • Then, with a twisting motion of clinician's hand and wrist, the needle is advanced through the bony cortex (the hard outer layer of the bone) and into the marrow cavity. (wikipedia.org)
  • The needle is then advanced with a twisting motion and rotated to obtain a solid piece of bone marrow. (wikipedia.org)
  • A needle is used to withdraw samples of the marrow from within the bone. (news-medical.net)
  • Infection
  • Bone marrow suppression due to anti-cancer chemotherapy is much harder to treat and often involves hospital admission, strict infection control, and aggressive use of intravenous antibiotics at the first sign of infection. (wikipedia.org)
  • debut
  • On September 4, 2015, Marrow released their debut full-length album Gold Standard via Foxhall Records. (wikipedia.org)
  • Marrow made his debut on 22 August 2012, coming on as a substitute for Jamie McGuire in the second half, as they lost 1-0 to Bradford City. (wikipedia.org)
  • commonly
  • Marrows are commonly cultivated in the British Isles, and the term "marrow" for the plant and for the fruit is still current there, especially for the striped, thicker-skinned cultivar. (wikipedia.org)
  • Courgettes are commonly described as marrows harvested young. (wikipedia.org)
  • American
  • Marrow is an American rock band from Chicago, Illinois. (wikipedia.org)
  • Marrow (Sarah), is a fictional superheroine appearing in American comic books published by Marvel Comics. (wikipedia.org)
  • Mitch Marrow (born July 16, 1975) is an American football player and business owner. (wikipedia.org)
  • Fort Marrow is a historic American Civil War fort and archaeological site located near Huttonsville, Randolph County, West Virginia. (wikipedia.org)
  • Vincent Charles Marrow (born August 17, 1968) is an American football coach and former NFL tight end. (wikipedia.org)
  • Queen Esther Marrow is an American soul and gospel singer. (wikipedia.org)
  • involve
  • Bone marrow transplantation does not involve the transfer of a discrete anatomic organ, as occurs in other forms of transplantation, but it does carry the same risk of rejection by the recipient, which is called graft-versus-host disease (GVHD). (britannica.com)
  • form
  • National Register of Historic Places Inventory Nomination Form: Fort Marrow" (PDF). (wikipedia.org)
  • In the 1730s, though over a different issue, that of patronage, some of the proponents of Marrow theology left the Church of Scotland to form the Associate Presbytery, with the distinctive doctrines of The Marrow forming the theological basis for the new church. (wikipedia.org)
  • In this form The Marrow has been frequently reprinted over the last nearly 300 years and has been widely influential. (wikipedia.org)