• The analyses were established separately for women and men, and associations were calculated by chi-square tests and linear and logistic regression analyses, adjusting for age, education level, smoking, physical activity, BMI, and energy intake. (helsinki.fi)
  • second, the estimated m is used for log- F -penalized logistic regression analyses of all variants using data augmentation with standard software. (karger.com)
  • Janowska J, Chudek J, Olszanecka-Glinianowicz M, Semik-Grabarczyk E, Zahorska-Markiewicz B. Interdependencies among Selected Pro-Inflammatory Markers of Endothelial Dysfunction, C-Peptide, Anti-Inflammatory Interleukin-10 and Glucose Metabolism Disturbance in Obese Women. (medsci.org)
  • inflammatory markers (called cytokines, in short cyto). (ethz.ch)
  • An increase in inflammatory markers is common in patients with anxiety disorders. (chiroeco.com)
  • 17,18 One review looked at patients with PTSD and found an increase in IL-6, TNF-alpha and other inflammatory markers. (chiroeco.com)
  • Patients with depression had higher levels of these inflammatory markers than did healthy controls. (chiroeco.com)
  • The injections produced both an increase in inflammatory markers and anxiety. (chiroeco.com)
  • Is PTSD symptom severity associated with metabolic and inflammatory markers? (psychiatrictimes.com)
  • Findings have not always been consistent in studies of cross-sectional associations between PTSD symptoms and inflammatory markers. (psychiatrictimes.com)
  • Recent studies have shown a relationship between inflammatory markers and modifiable lifestyle factors including fitness, diet, exercise and smoking. (who.int)
  • No association was observed between physical activity level and inflammatory markers. (who.int)
  • FLORENCE, Italy - Impaired cognition in first-episode psychosis appears to be associated with expression of inflammatory markers, say Spanish researchers in findings that could point to the eventual targeting of therapies to patient subgroups. (medscape.com)
  • Noting that there is increasing evidence to link cognitive function and inflammatory processes and that cognitive deficits are present from the onset of psychosis, the team examined connections between cognition and inflammatory markers in first-episode psychosis. (medscape.com)
  • The researchers then used hierarchical regression analysis to determine the impact of inflammatory markers on sustained attention and executive function, taking into account age, sex, body mass index, tobacco and cannabis use, and chlorpromazine -equivalent antipsychotic treatment. (medscape.com)
  • There were significant differences between district and provincial hospitals in the availability of microbial culture, rapid influenza diagnostic tests, inflammatory markers and mechanical ventilation. (who.int)
  • The primary endpoint was the measurement of inflammatory markers assessed preoperatively and at postoperative days 1, 2, 3, 5 and 7. (who.int)
  • We have studied the relationship between clinical and biochemical parameters and C-peptide and anti-inflammatory IL-10, as well as selected markers of inflammation and endothelial dysfunction such as: CCL2, CRP, sICAM-1, sVCAM-1 and E-selectin in obese women with various degree of glucose metabolism disturbance. (medsci.org)
  • All five inflammation markers were significantly associated with QUICKI. (hindawi.com)
  • These study findings suggest that inflammation measures may be potential early markers of cardiovascular risk in young asymptomatic individuals. (hindawi.com)
  • A large body of scientific evidence supports the critical role of inflammation markers (including adipokines, bioactive mediators secreted directly from adipocytes, and vascular cells within adipose tissue) in the development of systemic inflammation that contributes to vasculopathy and cardiovascular risk within obese individuals [ 1 , 2 ]. (hindawi.com)
  • Accordingly, the objective of this study was to investigate whether or not evidence of early pathogenesis involving inflammation markers is present in healthy young adult individuals, without diabetes or hypertension. (hindawi.com)
  • The study was designed to evaluate the role of inflammation markers in the development of insulin resistance, microvascular dysfunction, and endothelial dysfunction and eventually the progression to (pre)diabetes and (pre)hypertension. (hindawi.com)
  • 0.001) with plasma ferritin (inflammation marker). (rti.org)
  • After matching, the mean standardized differences of variables in the propensity score model improved, but a few variables remained slightly imbalanced, such as two markers of inflammation, inhaled corticosteroid use, and body mass index. (medscape.com)
  • We aimed to determine if clinical and biological markers of inflammation in the first year of life predict cognitive, language, and motor outcomes in children living in an urban slum in Bangladesh. (cdc.gov)
  • Febrile illness was used as a clinical marker of inflammation and elevated concentrations of inflammation-related cytokines (IL-1β, IL-6, TNF-α, IL-4, IL-10) in sera collected from a subset of the cohort (N = 127) at 6 months of age were used as biomarkers of inflammation. (cdc.gov)
  • Clinical and biological markers of inflammation in the first year of life were significantly associated with poor neurodevelopmental outcomes. (cdc.gov)
  • These findings suggest that markers of inflammation could serve as prognostic indicators and potentially lead to immune-based therapies to prevent developmental delays in at-risk children. (cdc.gov)
  • Infectious morbidity was assessed as the odds ratio (OR) with 95% confidence interval (CI) for doctor visit and antibiotics use during the first year of life based on parental reports and using binary logistic regression model. (helsinki.fi)
  • The diagnostic potential of IMs was evaluated using binary logistic regression analysis. (who.int)
  • Methods: This study was a secondary analysis of the observational, longitudinal Health and Early Life Microbiota (HELMi) cohort data, collected among healthy, term infants and their families during 2016 and 2019 in the capital region of Finland. (helsinki.fi)
  • Noting that the current investigation is a cross-sectional analysis, Cabrera said: "We have longitudinal data also, so now we can do a new study, with the same variables at baseline and 2 years later. (medscape.com)
  • The micro-array data were analysed to identify predictive markers, using a Random Forest algorithm combined with a logistic regression model. (biomedcentral.com)
  • While progress has been made in recent years in the characterisation of pulmonary carcinoids, little is known about the underlying biology or developmental origins of these molecular groups, hampering efforts to identify predictive markers and suitable therapeutic options. (who.int)
  • For simple regression analysis this shouldn't be a problem, but for more complex tasks it might cause performance issues when training. (enterprisedb.com)
  • Using simple regression, the proportion of brokens in the brown rice before milling (PB), explained 59.2% of the variance in HR, indicating this is an excellent predictor of milling yield. (usda.gov)
  • Data were analyzed by the product life table method and the Cox proportional hazards regression model. (cdc.gov)
  • To date, the proportional hazards (PH) regression model 11 has been the most widely used method. (nature.com)
  • A study of ridge regression and some examples of its application in multivariate analysis. (wikipedia.org)
  • Multivariate analysis revealed that treatment for pain problems in the previous 2 years and seeing a chiropractor for any reason explained the predictive power of the other variables in men, as did younger age and greater number of hospitalizations over the previous 10 years in women. (cdc.gov)
  • It has been hypothesized that multivariate analysis and systematic detection of epistatic interactions between explanatory genotyping variables may help resolve the problem of "missing heritability" currently observed in genome-wide association studies (GWAS). (springer.com)
  • The S-TOFHLA and REALM both were associated with the absolute difference between the MDGA and PTGA by linear regression, and results remained statistically significant in multivariate analysis. (jrheum.org)
  • According to univariate analysis, younger age was a significant marker for predicting acute back pain. (cdc.gov)
  • While commonly-used univariate analysis techniques have been able to detect a number of significantly associated loci, for many conditions these discovered variants do not account for a majority of the theoretical estimates of genetic heritability. (springer.com)
  • Theoretically, it has been shown that 2-way and 3-way single nucleotide polymorphism (SNP) interactions can explain up to ~ 50% and ~ 100% of trait variance while each SNP involved explains none [ 3 ], indicating that critical SNP pairs may be ignored by univariate analysis predominantly applied to GWAS so far. (springer.com)
  • Among the biomarkers she investigated, "only [IL-6] shows us in the logistic regression. (medscape.com)
  • A reliable diagnostic and prognostic marker for MM will significantly enhance clinical care and is an area of intense research. (bmj.com)
  • We analyzed the relation of several synchrony markers in the electroencephalogram (EEG) and Alzheimer's disease (AD) severity as measured by Mini-Mental State Examination (MMSE) scores. (nih.gov)
  • We conclude that several of the proposed EEG markers are related to AD severity for the overall sample with a wide dispersion for individual subjects. (nih.gov)
  • and I think that biological markers for severity made a good correlation" in this study, he noted. (medscape.com)
  • Our analysis highlighted the highly dynamic nature of STEC O157:H7 Stx-encoding bacteriophages and revealed the evolutionary history of a highly pathogenic clone emerging within sublineage IIb, a sublineage not previously associated with severe clinical symptoms. (cdc.gov)
  • The Lorraine strain and related Dutch and French Legionella strains contain a marker that encodes a RtxA protein which probably is involved in the increased prevalence in clinical isolates. (biomedcentral.com)
  • Using genomotyping to identify virulence markers, a recent study described four markers that could discriminate clinical isolates and environmental strains in a systematic collection of 222 Dutch Legionella strains [ 8 ]. (biomedcentral.com)
  • We evaluate the performance of a logistic regression model based on the four Dutch markers to adequately predict the origin of 114 clinical Legionella isolates and 105 environmental strains from France. (biomedcentral.com)
  • Material/Methods: We conducted a meta-analysis of observational studies evaluating the association of coagulation activation, fibrinolytic, and endothelial function with occurrence of AF and clinical adverse events. (uni-koeln.de)
  • Baseline data and clinical measurement data [spirometry, arterial blood gas analysis, and COPD evaluation test (the CAT scale)] from patients with AECOPD were collected. (dovepress.com)
  • Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. (scienceopen.com)
  • The relationship of the antibodies to the clinical course of mania was analyzed by the use of regression models. (greenmedinfo.com)
  • We compared the power of gene expression measurements with that of conventional prognostic markers, i.e., clinical, histo- pathological, and cell biological parameters, for predicting distant metastases in breast cancer patients using both established prognostic indices (e.g., the Nottingham Prognostic Index (NPI)) and novel combinations of conventional markers. (lu.se)
  • When analysing separately subgroups, according to the oestrogen receptor (ER) status both approaches could predict clinical outcome more easily for the ER-positive than for the ER-negative cohort. (lu.se)
  • Of the 18 associated SNPs, three polymorphisms, rs6920220, rs13207033 and rs5029937, remained significant after conditional logistic regression analysis. (whiterose.ac.uk)
  • Conditional analyses showed that anti-Ro and anti-La subsets are independently associated with HLA-DRB1*0301, and that the HLA-DRB1*03:01 association with SLE is largely but not completely driven by the association of this allele with these sub-phenotypes. (cdc.gov)
  • A linkage analysis was performed using a regression interval analysis. (cambridge.org)
  • SSR markers were used to anchor 532 AFLP markers in construction of a linkage map. (usda.gov)
  • Univariate Cox regression analysis showed that Annexin A2 and S100A10 in stromal tissue correlated with shorter overall survival (OS). (cancerindex.org)
  • The portal provides graphical summaries of gene-level data from multiple platforms, network visualization and analysis, survival analysis, patient-centric queries, and software programmatic access. (scienceopen.com)
  • The most important new feature is an option to upload entire, genome-wide datasets as input, allowing users to visualize subsets as interaction networks and to perform gene-set enrichment analysis on the entire input. (scienceopen.com)
  • European Journal of Cancer 40 (2004) 1837-1841 since approximately half of all new breast cancers are the St. Gallen criterion [1], which are based upon dif- diagnosed in the third world, where the analyses of ferent subsets of these conventional markers. (lu.se)
  • A genome examination using 85 informative molecular markers was conducted. (cambridge.org)
  • The combination of a mixed-genome micro-array and statistical analysis using a Random Forest algorithm has identified virulence markers in a consistent way. (biomedcentral.com)
  • Phylogenetic analyses of whole genome sequencing data indicated that Mycobacterium tuberculosis isolates from all 11 patients with culture-confirmed TB were closely related, suggesting that these cases represented a single outbreak. (cdc.gov)
  • The current study performed differentially expressed analyses between normal tissues and tumor tissues. (biomedcentral.com)
  • Our study provides a systematic analysis of EEG synchrony based on a large and homogeneous sample. (nih.gov)
  • The study included more than 225 cases and 300 controls, which allowed for sub-analyses by gender and trauma type. (psychiatrictimes.com)
  • Min regularly uses ventricular pressure-volume (PV) analyses to characterize and study cardiac hypertrophy. (adinstruments.com)
  • A recent study, using a Dutch Legionella strain collection, identified five virulence associated markers. (biomedcentral.com)
  • In our study, we verify whether these five Dutch markers can predict the patient or environmental origin of a French Legionella strain collection. (biomedcentral.com)
  • The aim of this study was to examine whether Annexin A2 and S100A10 expression can be used as prognostic markers for epithelial ovarian cancer (EOC). (cancerindex.org)
  • We study penalized logistic regression using a class of log- F priors indexed by a shrinkage parameter m to shrink the biased MLE toward zero. (karger.com)
  • G Increase the Susceptibility to Arsenic-Induced Skin Cancer: A Cohort Study and In Silico Analysis of Mutation Impacts. (cdc.gov)
  • 13 Our study substantially expands this work by not only analysing imputed classical human leukocyte antigen (HLA) alleles, but also examining variant HLA amino-acid positions in conjunction with single-nucleotide polymorphism (SNP) genotypes across the extended MHC region (chromosome 6: 26-34 Mb). (cdc.gov)
  • This study sought evidence for the validity for the Reduced Markers Scale (EMR) in a population of university students ( n =175, mean age=28.5, SD =7.4). (bvsalud.org)
  • This was expression markers identified in the study by van 't Veer done by sequentially leaving one patient out for a blind and colleagues [2] compare with conventional markers. (lu.se)
  • Following data quality control, we analysed 22 single nucleotide polymorphisms (SNPs) on 12 candidate genes. (nature.com)
  • Similarly, multiple-SNPs analysis revealed joint effects of rs2134655, rs172677 and rs1079597, with an adjustment for habitual smoking. (nature.com)
  • Reducing the set of analysed SNPs before bivariate analysis could easily omit such critical loci. (springer.com)
  • Exhaustive analysis of studies containing approximately 450,000 SNPs and 5,000 samples requires only 2 hours using a desktop CPU or 13 minutes using a GPU (Graphics Processing Unit). (springer.com)
  • Even in only bivariate analysis, the number of possible SNP interactions that need to be searched is extremely large, as there are 125 billion possible SNP pairs in a GWAS of 500,000 SNPs. (springer.com)
  • Locally weighted PCA regression to recover missing markers in human motion data. (bournemouth.ac.uk)
  • Increasingly, logistic regression methods for genetic association studies of binary phenotypes must be able to accommodate data sparsity, which arises from unbalanced case-control ratios and/or rare genetic variants. (karger.com)
  • These data have been combined with previously published LNET data to perform integrative analysis using multi-omics factor analysis (MOFA), resulting in a molecular map of lung neuroendocrine neoplasms for exploration. (who.int)
  • However, not all of the blood markers of endothelial dysfunction and coagulation increased consistently in association with air pollutants. (nih.gov)
  • Fixed-effects linear and logistic regression models were applied, adjusting for trend, weekday, and meteorologic parameters. (nih.gov)
  • Analyses were conducted via multiple linear regression. (hindawi.com)
  • Infant growth was analysed with general linear model for repeated measures of WHO z-scores: weight-for age (WFA), weight-for-length (WFL), BMI-for-age (BMIFA), and length-for-age (LFA). (helsinki.fi)
  • By coupling the analysis with gas chromatography-mass spectrometry (GC-MS), excellent detection limits (0.01-0.2 mug L(-1)), good precision (RSDs, 3.33-6.56%) and linear ranges (0.10-160 mug L(-1) and 1.0-160 mug L(-1)) were obtained. (who.int)
  • We used validated instruments [Short Test of Functional Health Literacy in Adults (S-TOFHLA) and Rapid Estimate of Adult Literacy in Medicine (REALM)] and linear regression to determine whether health literacy predicts disease measure discrepancy. (jrheum.org)
  • Multivariable linear regression analyses in RBC-Omics revealed that BMI was a significant modifier for all hemolysis measurements, explaining 4.5%, 4.2%, and 0.2% of the variance in osmotic, oxidative, and storage hemolysis, respectively. (rti.org)
  • Subsequent analyses identified four predictive markers for the French collection that were used for the logistic regression model. (biomedcentral.com)
  • We have developed an exhaustive bivariate GWAS analysis methodology that yields a manageable subset of candidate marker pairs for subsequent analysis using other, often more computationally expensive techniques. (springer.com)
  • In sum, these results identify primate IT activity as a candidate neural marker and demonstrate how ANN models of vision can be used to generate neural circuit-level hypotheses and guide future human and non-human primate studies in autism. (biorxiv.org)
  • The results indicate that the individual markers capture different aspects of EEG synchrony and may reflect cerebral compensatory mechanisms in the early stages of AD. (nih.gov)
  • Heterogeneities among studies were found for most markers, and meta-regressions indicated that age and publication year may influence the meta-analysis results. (nature.com)
  • Soluble mesothelin is the most studied and an FDA-approved biomarker for MM. A recent report showed promising results using fibulin-3 as a new diagnostic marker. (bmj.com)
  • Breen and colleagues 4 undertook a mega-analysis using the results from 5 PTSD transcriptome studies. (psychiatrictimes.com)
  • Experimental Design: Bcl -6, CD10, and CD40 were chosen as markers for a germinal center phenotype, CD23 as a marker of pre/early germinal center origin, and CD138 as a marker for postgerminal center origin. (aacrjournals.org)
  • Conclusions: The levels of coagulation, fibrinolytic, and endothelial markers have been reported to be significantly higher in AF patients than in SR patients. (uni-koeln.de)
  • Individuals with mania had significantly increased levels of IgG antibodies to gliadin, but not other markers of celiac disease, at baseline compared with controls in multivariate analyses. (greenmedinfo.com)
  • He acknowledged certain limitations of the analysis, including its observational design. (medscape.com)
  • Here we aimed to investigate blood oxidative stress marker profile in ASD children by a meta-analysis. (nature.com)
  • BALF from paediatric and adult CF patients and paediatric disease controls undergoing clinically indicated bronchoscopy was analysed for total bacterial load and for microbiota by 16S rDNA sequencing. (ersjournals.com)
  • Breast cancer patients can be cured either by local markers are therefore called for. (lu.se)
  • Receiver operating characteristic curve (ROC) analysis demonstrated that λ FLCs may serve as a serum marker for identifying dengue disease (AUC: 0.7825, sensitivity: 80, specificity: 71.43) and classifying severe dengue (AUC: 0.8102, sensitivity: 75, specificity: 79.52). (bvsalud.org)
  • In sensitivity analyses with modified cohort eligibility requirements, no significant differences in outcomes were observed between non-TNFi/JAKi and TNFi initiators. (medscape.com)
  • Nevertheless, these methods are only used for the qualitative or quantitative analysis of one type terpenoid (triterpenoid or sesquiterpenoid). (hindawi.com)
  • Using these methods to analyse a dichotomous disease event alone ignores the probability of later disease onsets in currently healthy subjects and incorrectly considers that all subjects with diseases equally contribute to the likelihood for inference, irrespective of differences in their onset age. (nature.com)
  • Our model-free filtering approach is based on classification using ROC curve analysis, an alternative to much slower regression-based modelling techniques. (springer.com)
  • All scans were performed by regression model was done for detec- more body fat have lower rates of bone trained physicians and analysed by the tion of the independent risk factors resorption (an independent predictor researcher. (who.int)
  • nificance of individual coefficients in the en, bone mineral status is much more Daily routine calibration was done model was assessed by the Hosmer- closely associated with total body fat using the standard phantom supplied Lemeshow test for goodness of fit and [4] and in a multivariate model total fat by the manufacturer. (who.int)
  • Nevertheless, an association between hemolysis and pulmonary hypertension in sickle cell disease has been questioned because, in most studies thus far, not all markers of hemolysis have had significant associations with estimated pulmonary artery pressure. (haematologica.org)
  • In recent exploratory regional therapy alone or by the addition of systemical studies, markers from microarray gene expression medical therapy with increased side effects and costs. (lu.se)
  • Cardiac vagal tone, indexed via heart rate variability (HRV), is one prominent marker of such visceral functioning. (frontiersin.org)
  • We conducted a meta-analysis of four independent European SLE case collections for associations between SLE sub-phenotypes and MHC single-nucleotide polymorphism genotypes, human leukocyte antigen (HLA) alleles and variant HLA amino acids. (cdc.gov)
  • Analysis of twenty-four traits identified sixty-five QTLs in sixteen chromosomal regions affecting these traits. (usda.gov)
  • Brown rice (BR), milled rice (MR), and head rice (HR) recovery were analyzed with 35 sub-component traits using forward stepwise regression modeling (SAS). (usda.gov)
  • They proved through factorial analysis that these five factors were a sufficient representation of all human personality framework traits. (bvsalud.org)
  • To date there exists little experimentally-validated evidence of SNP interactions in humans, largely due to the complexity of multivariate GWAS analysis. (springer.com)
  • A web-based version of the software used for this analysis is available at http://bioinformatics.research.nicta.com.au/gwis . (springer.com)
  • The meta-analysis showed that blood concentrations of oxidative glutathione (GSSG), malondialdehyde, homocysteine, S -adenosylhomocysteine, nitric oxide, and copper were higher in children with ASD than that of HC children. (nature.com)
  • Catalase C262T genetic variation and cancer susceptibility: A comprehensive meta-analysis with meta-regression and trial sequential analysis. (cdc.gov)
  • The aims of quantitative trait loci detection is the potential use of these molecular markers to increase accuracy in predicting the genetic merit of breeding and its implementation in animal breeding schemes through marker-assisted selection. (cambridge.org)
  • Short-term physical health markers in younger officers may not be an index of psycho-social effects. (cdc.gov)
  • Here, I have used brain-tissue mapped artificial neural network (ANN) models of primate vision to probe candidate neural and behavior markers of atypical facial emotion recognition in IwA at an image-by-image level. (biorxiv.org)
  • Using a variety of techniques including animal models of ventricular hypertrophy, gene knockouts, and hemodynamic analyses - Min and collegues have successfully identified some key proteins involved in the development of cardiac hypertrophy as well as potential drug targets and therapies for treating the disease 3,4,5 . (adinstruments.com)
  • The primary outcome was a composite of time to respiratory-related hospitalization or death using Cox regression models. (medscape.com)
  • However, there were no significance differences between ASD children and HC children for the other 17 potential markers. (nature.com)
  • In addition, we identify new potential virulence markers and verify whether these can predict better. (biomedcentral.com)
  • A comprehensive subgroup analysis and meta-regression was performed to explore potential sources of heterogeneity. (uni-koeln.de)
  • Additionally, we found a number of new potential RA markers, including rs5029937, located in the intron 2 of TNFAIP3. (whiterose.ac.uk)
  • The expression of both markers correlated to histological subtype, histological grading, International Federation of Gynecology and Obstetrics (FIGO) stage, and macro-radical surgery. (cancerindex.org)
  • Here, we provide a practical guide to the analysis and visualization features of the cBioPortal for Cancer Genomics. (scienceopen.com)
  • Immunohistochemical analysis was performed using the EnVision method. (aacrjournals.org)
  • multivariate logistic regression analysis found that tortilla chips were the only food item associated with illness. (cdc.gov)
  • Three of the French markers differed from the Dutch markers, one showed considerable overlap and was found in one of the Legionella genomes (Lorraine strain). (biomedcentral.com)
  • however, no independent prognostic value was found for any of the markers. (cancerindex.org)
  • The developed method efficiently determined the 10 marker compounds in RA and was subsequently applied to optimise harvest time and crude processing temperature. (hindawi.com)
  • We propose the locally weighted principal component analysis (PCA) regression method to deal with this challenge. (bournemouth.ac.uk)
  • Our experiments show that the proposed regression method can reach high estimation accuracy and has a good numerical stability. (bournemouth.ac.uk)
  • Satisfactory recoveries were achieved when the method was used for the analysis of AAs in spiked real water samples. (who.int)