Smad3 ProteinSmad4 ProteinSmad7 ProteinSmad1 ProteinSmad5 ProteinSmad ProteinsSmad8 ProteinTransforming Growth Factor betaSignal Transductionp38 Mitogen-Activated Protein KinasesMitogen-Activated Protein KinasesMAP Kinase Signaling SystemTrans-ActivatorsPhosphorylationTransforming Growth Factor beta1DNA-Binding ProteinsBone Morphogenetic ProteinsReceptors, Transforming Growth Factor betaEnzyme ActivationMitogen-Activated Protein Kinase KinasesMitogen-Activated Protein Kinase 1Cells, CulturedMitogen-Activated Protein Kinase 3Cell LineActivinsProtein-Serine-Threonine KinasesImidazolesBlotting, WesternExtracellular Signal-Regulated MAP KinasesPyridinesEnzyme InhibitorsBone Morphogenetic Protein 2Gene Expression RegulationMitogen-Activated Protein Kinase 14JNK Mitogen-Activated Protein KinasesProtein BindingTranscription, GeneticFlavonoidsTransfectionRNA, MessengerCell Line, TumorButadienesCOS CellsPromoter Regions, GeneticCalcium-Calmodulin-Dependent Protein KinasesBone Morphogenetic Protein ReceptorsReverse Transcriptase Polymerase Chain ReactionCell ProliferationCell DifferentiationDual Specificity Phosphatase 1Bone Morphogenetic Protein Receptors, Type ITranscriptional ActivationBone Morphogenetic Protein 4RNA, Small InterferingMinkBone Morphogenetic Protein 7Transcription FactorsCell NucleusMAP Kinase Kinase KinasesMice, KnockoutLuciferasesFibrosisApoptosisXenopus ProteinsFibroblastsTransforming Growth Factor beta2MAP Kinase Kinase 4MAP Kinase Kinase 3Molecular Sequence DataGenes, ReporterUp-RegulationDown-RegulationModels, BiologicalEpithelial CellsMutationActivin ReceptorsNitrilesActive Transport, Cell Nucleusras ProteinsMice, Inbred C57BLPhosphatidylinositol 3-KinasesIntracellular Signaling Peptides and ProteinsMesodermCollagen Type IGene Expression Regulation, DevelopmentalTime FactorsRats, Sprague-DawleyCell DivisionActivin Receptors, Type IIProtein Structure, TertiaryProto-Oncogene Proteins c-rafRNA InterferenceConnective Tissue Growth FactorImmunoblottingNF-kappa BImmunoprecipitationUbiquitin-Protein LigasesAmino Acid SequenceNodal ProteinBase Sequence