ras Guanine Nucleotide Exchange FactorsSon of Sevenless Proteinsras-GRF1Guanine Nucleotide Exchange Factorsras ProteinsGRB2 Adaptor ProteinAmino Acid MotifsGenes, rasp38 Mitogen-Activated Protein KinasesMitogen-Activated Protein KinasesEnzyme ActivationMAP Kinase Signaling SystemProto-Oncogene Proteins p21(ras)Signal TransductionMolecular Sequence DataPhosphorylationMitogen-Activated Protein Kinase 1Oncogene Protein p21(ras)Amino Acid SequenceMitogen-Activated Protein Kinase KinasesMitogen-Activated Protein Kinase 3Protein BindingCalcium-Calmodulin-Dependent Protein KinasesCell LineProto-Oncogene Proteins c-rafEnzyme InhibitorsCells, CulturedBase SequenceImidazolesPyridinesJNK Mitogen-Activated Protein KinasesProtein Structure, TertiaryFlavonoidsMutationNucleotide MotifsKineticsExtracellular Signal-Regulated MAP Kinasesras GTPase-Activating ProteinsMAP Kinase Kinase 3TransfectionBlotting, WesternProtein-Serine-Threonine KinasesBinding SitesDeuterium Exchange MeasurementDual Specificity Phosphatase 1Sequence Homology, Amino AcidModels, MolecularProtein-Tyrosine KinasesButadienesRecombinant ProteinsPulmonary Gas ExchangeMitogen-Activated Protein Kinase 14Models, BiologicalProteinsExchange Transfusion, Whole BloodDNA-Binding ProteinsTranscription FactorsRecombinant Fusion ProteinsSister Chromatid ExchangeGene Expression RegulationMAP Kinase Kinase KinasesMAP Kinase Kinase 4RNA, MessengerPhosphatidylinositol 3-KinasesProto-Oncogene ProteinsMAP Kinase Kinase 13T3 CellsMutagenesis, Site-DirectedCarrier ProteinsApoptosisNitrilesMembrane ProteinsMAP Kinase Kinase 6Protein Kinase CDNACOS CellsTyrosineCell Line, TumorTranscription, GeneticAdaptor Proteins, Signal TransducingTime FactorsPromoter Regions, GeneticCell DivisionRats, Sprague-DawleyDose-Response Relationship, DrugCalciumSequence AlignmentConserved SequenceIntracellular Signaling Peptides and ProteinsImmunoblottingTumor Cells, CulturedShc Signaling Adaptor ProteinsHeLa CellsProtein KinasesPeptidesGTP-Binding ProteinsNF-kappa BProtein TransportGuanosine TriphosphateGuanosine Diphosphate