• Ethical and practical considerations arising from community consultation on implementing controlled human infection studies using Schistosoma mansoni in Uganda. (lshtm.ac.uk)
  • A recent research article published in Parasites & Vectors by Joaquin Prada and colleagues encompasses some of these issues by comparing two widely used diagnostic tests for intestinal schistosomiasis (caused by Schistosoma mansoni ) in Uganda. (biomedcentral.com)
  • The main objective of this study was to assess the prevalence and risk factors associated with Schistosoma (S.) mansoni infection among PSAC from Panamasso village, western Burkina Faso. (researchsquare.com)
  • The prevalence of S. mansoni infection as determined by Kato-Katz, formol-ether concentration, and POC-CCA was 42.1%, 39.5% and 80.7%, respectively. (researchsquare.com)
  • In 2010, the prevalence of S. mansoni infection among SAC ranged from 3.3 to 39.1% with the highest prevalence (39.1%) recorded in Panamasso village (23). (researchsquare.com)
  • BackgroundThe prevalence of Schistosoma mansoni infection is usually assessed by the Kato-Katz diagnostic technique. (researcher.life)
  • This study provides estimates of the 'true' S. mansoni prevalence from population summary measures of observed prevalence and infection intensity using extensive simulations parametrized with data from different settings in sub-Saharan Africa.MethodologyAn individual-level egg count model was applied to Kato-Katz data to determine the S. mansoni infection intensity-dependent sensitivity for various sampling schemes. (researcher.life)
  • The relation between observed and 'true' prevalence is remarkably linear and triplicate slides per day on three consecutive days ensure close to perfect sensitivity.Conclusions/significanceEstimation of 'true' S. mansoni prevalence is improved when taking into account geometric or arithmetic mean infection intensity in a population. (researcher.life)
  • This species is African, and occurs in: Lake Albert, Uganda. (wikipedia.org)
  • Lake Albert is between Uganda and Democratic Republic of the Congo) Lake Chad Lake Cohoha in Burundi A cladogram showing phylogenic relations of species in the genus Biomphalaria: Biomphalaria stanleyi is found in deeper water in Lake Albert. (wikipedia.org)
  • S. mansoni was the sole species infecting a high proportion of PSAC in the study area. (researchsquare.com)
  • In Burkina Faso, S. mansoni infection was endemic in the western and southern areas of the country with a focal distribution before the implementation of the national schistosomiasis control program (NSCP) in 2004 (21). (researchsquare.com)
  • Schistosoma mansoni and Plasmodium falciparum are co-endemic in Uganda and are the leading parasitic causes of public health problems across sub-Saharan Africa. (scirp.org)
  • Methodology: This study evaluated the T helper immune responses in individuals with independent S. mansoni infection, independent P. falciparum infection, co-infection and non-infection in school attending children in a co-endemic area along Lake Victoria shores, Uganda. (scirp.org)
  • This systematic review was conducted to identify gaps and recent progress on the efficacy of different regimens of praziquantel in treating schistosomiasis among children in sub-Saharan Africa where Schistosoma mansoni and S. haematobium are endemic. (biomedcentral.com)
  • Urine samples were subjected to a point-of-care circulating cathodic antigen (POC-CCA) cassette test and a centrifugation method to check for both S. mansoni and S. haematobium infection, respectively. (researchsquare.com)
  • The search included studies published from 2008 to 2017 (August) with emphasis on the efficacy of praziquantel on S. haematobium and S. mansoni infections among preschool and school children. (biomedcentral.com)
  • The review indicates that further investigations are necessary to conclusively determine efficacy of praziquantel on coinfection of S. haematobium and S. mansoni to formulate concrete guidelines on the use of repeated doses at 40 or 60 mg/kg for treating schistosomiasis. (biomedcentral.com)
  • Mwangia IN,.Sanchez MC, Mkoji GM, Agola LE, Runo SM, Cupit PM, Cunningham C. Praziquantel sensitivity of Kenyan Schistosoma mansoni isolates and the generation of a laboratory strain with reduced susceptibility to the drug. (ac.ke)
  • Effect of Four Rounds of Annual School-Wide Mass Praziquantel Treatment for Schistosoma Mansoni Control on Schistosome Specific Immune Responses. (ac.ke)
  • Kato Katz thick smears and circulating cathodic antigen tests were performed for S. mansoni screening, whereas thick and thin blood smear techniques were performed for P. falciparum screening. (scirp.org)
  • Circulating cathodic antigen test (CCA) detects S. mansoni gut antigens that are regurgitated by the worm during active blood feeding and are therefore present in host urine. (biomedcentral.com)
  • To explore the possibility of establishing the CHI-S in Uganda, a Stakeholders' Meeting was held in Entebbe in 2017. (kemri-wellcome.org)
  • After my PhD I carried out multi-locus genotyping on S. mansoni miracidia from Uganda, to analyse parasite diversity, heterozygosity and population structure and how they alter over time with PZQ exposure. (imperial.ac.uk)
  • 2019. Treatment of helminth Schistosoma mansoni infection in Ugandan women reduces HIV entry into cervical CD4 T cells and induces type I interferon pathways. (saragoodlab.com)
  • Although several studies have reported prevalences of S. mansoni infection ranging from 0.9 to 86% in PSAC (6,10-19), the risk factors associated with this parasite infection remain poorly studied (11,12,14,16,20). (researchsquare.com)
  • Described from 2008 and published in a case report in 2019, a 14-year-old schoolboy from a Paris suburb visiting the Ivory Coast, his parents' native country, was found with hematuria and S haematobium-S mansoni hybrid infection. (medscape.com)
  • Objectives: The overall aim was therefore, to elucidate the impact of S. mansoni infection on protective T helper immune responses on P. falciparum and S. mansoni co-infection. (scirp.org)
  • Suboptimal T helper immune responses were detected in independent S. mansoni infections characterized by significantly down regulated Th1 (Z = -1.425, p = 0.0313) response in comparison to the non-infected group. (scirp.org)
  • P. falciparum and S. mansoni infections initiate a T helper immune response [4] [5] , which links the innate and adaptive immune responses against the parasites. (scirp.org)
  • We explore adolescent boys and young men's PrEP uptake preferences in South Africa, Uganda, and Zimbabwe. (bvsalud.org)
  • However, findings on efficacy of repeated doses in co-infection of S. mansoni and S. haematobium were not conclusive. (biomedcentral.com)
  • A report by the Uganda onchocerciasis use the methodology developed by and conditions termed the "Aleppo boil," "Jericho boil," and the "Baghdad boil. (mooncarecenter.com)
  • Parasitic worm infections often trap people in a cycle of poverty, and almost a quarter of the population in Uganda is living below the poverty line. (unlimithealth.org)
  • In this theses project, we aim to investigate the interplay between P. yoelii and S. mansoni in a murine model using cutting-edge biological and molecular approaches to advance knowledge into the underlying mechanisms of interaction and its potential implications for parasites' virulence and transmission. (franceetcroissant.com)
  • NTDs in Uganda are managed by the NTD Control Programme (NTDCP), housed in the Vector Borne and NTD Division of the Ministry of Health (VB & NTDs - MoH). (unlimithealth.org)
  • Girls (AOR = 2.9, 95% CI: 1.3-6.1), a household located within 500 m from the pond (AOR = 3.0, 95% CI: 1.0-8.6), or between 500 and 1000 m from the pond (AOR = 3.0, 95% CI: 1.2-7.2), and child's history of going to the pond (AOR = 5.0, 95% CI: 1.7-14.3) were the variables significantly associated with S. mansoni infection. (researchsquare.com)
  • Early research carried out during my PhD, contributed to the paper  Development and application of an ethically and epidemiologically advantageous assay for the multi-locus microsatellite analysis of Schistosoma mansoni  which was awarded the 2007 parliamentary 3R s prize for the replacement, refinement and reduction of animals in research. (imperial.ac.uk)
  • In school-aged children (SAC) (i.e. 6-15 years), chronic infections with S. mansoni cause anemia, growth retardation and cognitive impairment (5). (researchsquare.com)
  • The main morbidities due to S. mansoni infection in preschool-aged children (PSAC) i.e. under 6 years, are anemia, hepatosplenomegaly, and hepatic fibrosis with a higher risk in PSAC of age group 37-60 months (6). (researchsquare.com)
  • Children play next to one of the boats at the riverfront in Buwaiswa village, Uganda. (unlimithealth.org)
  • Uganda delivers treatments to people affected by parasitic infections both through schools and in the community. (unlimithealth.org)
  • During two evaluations of refugee populations in western Uganda in March and July 2015, refugees with splenomegaly on physical examination were offered additional assessment and treatment, including abdominal ultrasonography and laboratory testing. (cdc.gov)
  • Schistosoma haematobium or S. mansoni and large-scale control efforts include providing regular treatment to at-risk groups and supporting drug delivery through schools. (who.int)
  • Conocida también en Latinoamérica como la by trauma and may cause mild that herbs dont typically kill so standard treatment, has been shown to a long time. (mooncarecenter.com)
  • PSAC have been considered as a low risk group for S. mansoni infection (7,8), and are therefore so far excluded from various schistosomiasis control programs in Africa, resulting in a health inequity in affected people (9). (researchsquare.com)
  • Control and elimination of NTDs is part of the Uganda National Minimum Care Package as highlighted in the Health Sector Development Plan II. (unlimithealth.org)
  • GI) endoscopy in the 1970s and the subse- data Indications for the procedure and en- quent development of smaller instruments doscopic findings were recorded. (who.int)
  • We built a spatial CRF to estimate infection risks for Ascaris lumbricoides , Trichuris trichiura , hookworms ( Ancylostoma duodenale and Necator americanus ) and Schistosoma mansoni using data from a national survey of Rwandan schoolchildren. (biomedcentral.com)
  • The Wellbeing of Older People Study in Uganda is an open cohort of adults aged 50+ with and without HIV, established in 2009. (bvsalud.org)
  • One study from Uganda dissolved in 1 L of water before being drunk on upper GI endoscopy in adolescents with by the child over 24 hours. (who.int)