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  • backbone
  • The endo-beta-mannanases (MANs) that catalyse the random hydrolysis of the beta-linkage in the mannan backbone are one of the main hydrolytic enzymes involved in the loosening and remodelling of CWs. (upm.es)
  • This type of mannan has a α(1-6) linked backbone and α(1-2) and α(1-3) linked branches. (wikipedia.org)
  • enzyme
  • Direct fluorescence imaging using a mannan-specific carbohydrate-binding module and sequential enzyme treatments with an endo-β-mannanase confirmed the presence of cryptic epitopes and that the masking of primary cell wall mannan by pectin is a potential mechanism for controlling cell wall micro-environments. (nih.gov)
  • wild-type mice
  • Mannan treatment did not alter most hallmarks of allergic airways disease in wild-type mice. (hindawi.com)
  • Previously we established that immunization of wild-type mice with mannan-Abeta28 conjugate promoted Th2-mediated humoral and cellular immune responses. (nih.gov)
  • mice
  • Transgenic mice treated with mannan during allergen exposure had an equivalent response to non-mannan-treated allergic mice except for a prominent granulocytic influx into airways and cytokine availability. (hindawi.com)
  • Mannan-Abeta28 conjugate prevents Abeta-plaque deposition, but increases microhemorrhages in the brains of vaccinated Tg2576 (APPsw) mice. (nih.gov)
  • Humoral immune responses induced by the immunization of mice with mannan-Abeta28 conjugate were analyzed using a standard ELISA. (nih.gov)
  • Immunizations with low doses of mannan-Abeta28 induced potent and long-lasting anti-Abeta humoral responses in Tg2576 mice. (nih.gov)
  • Vaccination with mannan-Abeta28 prevented Abeta plaque deposition, but unexpectedly increased the level of microhemorrhages in the brains of aged immunized mice compared to two groups of control animals of the same age either injected with molecular adjuvant fused with an irrelevant antigen, BSA (mannan-BSA) or non-immunized mice. (nih.gov)
  • Of note, mice immunized with mannan-Abeta28 showed a trend toward elevated levels of CAA in the neocortex and in the leptomeninges compared to that in mice of both control groups. (nih.gov)
  • Mannan conjugated to Abeta28 provided sufficient adjuvant activity to induce potent anti-Abeta antibodies in APP transgenic mice, which have been shown to be hyporesponsive to immunization with Abeta self-antigen. (nih.gov)
  • However, in old Tg2576 mice there were increased levels of cerebral microhemorrhages in mannan-Abeta28 immunized mice. (nih.gov)
  • This effect was likely unrelated to the anti-mannan antibodies induced by the immunoconjugate, because control mice immunized with mannan-BSA also induced antibodies specific to mannan, but did not have increased levels of cerebral microhemorrhages compared with non-immunized mice. (nih.gov)
  • antibodies
  • Whether these anti-mannan antibodies increased the permeability of the blood brain barrier thus allowing elevated levels of anti-Abeta antibodies entry into cerebral perivascular or brain parenchymal spaces and contributed to the increased incidence of microhemorrhages remains to be investigated in the future studies. (nih.gov)
  • MANs
  • This review updates and discusses the significance of mannans and MANs in seeds and explores the increasing biotechnological potential of MAN enzymes. (upm.es)
  • detection
  • In secondary cell walls, mannan esterification can prevent probe recognition of epitopes/ligands, and detection of mannans in primary cell walls can be effectively blocked by the presence of pectic homogalacturonan. (nih.gov)
  • cell wall
  • Masking by pectic homogalacturonan is shown to be a widespread phenomenon in parenchyma systems, and masked mannan was found to be a feature of cell wall regions at pit fields. (nih.gov)
  • growth
  • growth by Kayode Mannan diverse instrumentation ranging from arp's to piano's, basses and drums, emotional, for use in film. (productiontrax.com)
  • In the present study, to take full advantage of adenovirus in gene expression, we prepared mannan-modified recombinant adenovirus using the PTEN gene (Man-Ad5-PTEN) and investigated the effect of Man-Ad5-PTEN combined with docetaxel (Man-Ad5-PTEN-docetaxel) on tumor growth in a murine model of hepatocellular carcinoma. (dovepress.com)
  • The mannan-oligosaccharides are able to alter the composition of the microbiota present in the bowels, so they produce an increase in the growth of benign bacteria and therefore an increase in the resistance to infection by pathogens. (wikipedia.org)
  • Mannan oligosaccharides (MOSs) are often referred to as one of the potential alternatives for antimicrobial growth promoters. (mdpi.com)
  • Mannan oligosaccharides (MOSs) are often referred to as a potential alternative for antibiotic growth promoters. (mdpi.com)
  • high
  • european shotokan by Kayode Mannan for use in film, has a high upbeat tempo and diverse instrumentation. (productiontrax.com)
  • Mannan Castle is a motte (12.5 m high) and inner bailey connected by a causeway with a ditch and an outer bailey without a ditch. (wikipedia.org)
  • form
  • The endosperm CWs of dry seeds often contain mannan polymers, sometimes in the form of galactomannans (Gal-mannans). (upm.es)
  • ruling party
  • In reply to a question about mysterious telephone calls received by the ruling party legislators, Mr Mannan said that some of them apprised the prime minister of such calls. (thefreedictionary.com)
  • away
  • Mannan confessed that three members of the Al-Badr who were his students took away Dr Abdul Alim Chowdhury. (wikipedia.org)