Mouse embryo assay to evaluate polydimethylsiloxane embryo-toxicity. (nc3rs.org.uk)
The pronuclear H3K9me2 depositing assay and also the pre-implantation embryonic improvement potential were evaluated to look into the effect associated with fertilization-dependent ERK1/2 upon zygotic reprogramming as well as developing prospective. (cftrpathway.com)
Competence2
The team at University of Leeds led by Dr Virginia Pensabene has developed a novel and reliable microfluidic device that improves the developmental competence of in vitro -derived mouse embryos to allow the use of non-surgical embryo transfer (NSET) in the generation of transgenic mice. (nc3rs.org.uk)
The team at University of Leeds led by Dr Virginia Pensabene has developed a novel and reliable microfluidic device that improves the developmental competence of in vitro -derived mouse embryos and their implantation potential, enabling the use of non-surgical embryo transfer (NSET) in the generation of transgenic mice. (nc3rs.org.uk)
Vitro3
The aim of this Challenge was to generate an approach that improves the implantation rates of early stage embryos when combined with extended in vitro culture and non-surgical embryo transfer techniques. (nc3rs.org.uk)
Sponsored by MRC Harwell, the EASE Challenge aims to generate an approach that improves the implantation rates of early stage embryos when combined with extended in vitro culture and non-surgical embryo transfer techniques. (nc3rs.org.uk)
For example, pre-implantation genetic diagnosis ("PGD") has grown to be a common service at fertility clinics, allowing couples undergoing in vitro fertilization to test multiple embryos for genetic disorders before deciding which one to implant. (nyu.edu)
Genetically4
Genetically altered (GA) mice are used extensively to study the function and regulation of genes and their role in human development and disease. (nc3rs.org.uk)
In 2015, approximately 50% of the animals used for scientific procedures in the UK were for the creation and breeding of genetically modified animals, the majority of which are mice (Home Office, 2015). (nc3rs.org.uk)
Advances in the biotechnology industry have increased scientists' understanding of the human genome and enhanced their ability to genetically modify eggs, sperm, and human embryos. (nyu.edu)
If biotech scientists have the ability to manipulate the genes of an embryo or gamete cell for non-therapeutic purposes, it could be argued that these genetically modified cells are in fact patentable "inventions," given that the material was not, in that particular sequence, naturally occurring. (nyu.edu)
Model2
This pre-clinical model demonstrates the high efficiency and potential of the MST technique, not only to prevent the transmission of mtDNA mutations, but also as a new potential treatment for patients with certain forms of infertility refractory to current clinical strategies. (elifesciences.org)
[ 5 ] generated a novel mouse model for a hepatic disorder. (encyclopedia.pub)