Management of carotid body tumors. Medical search. Frequent questions

Carotid body tumors (CBTs) are rare neoplasms, although they represent about 50-60% of head and neck paragangliomas. (medscape.com)
When choosing treatment, consider the following factors: the presence of other paragangliomas, the presence of bilateral carotid body tumors (CBTs), the age and the health of the patient, and the patient's preference. (medscape.com)
[ 9 ] Carotid body tumors (CBTs) constitute about 50-60% of head and neck paragangliomas. (medscape.com)
Carotid paraganglioma (carotid body tumor): Is the most common of the head and neck paragangliomas. (wikipedia.org)
Case report: A female patient of 32 years old complaining of tinnitus and diagnosed with five paragangliomas (jugulo-timpanic, bilateral carotid body and bilateral brachiocephalic trunk) through imaging studies. (scirp.org)
Paragangliomas arise from paraganglion cells which serve varied regulatory tasks in the body. (springeropen.com)
Head and neck paragangliomas most common anatomic locations include the carotid space, jugular foramen, middle ear, and along the course of the vagus nerve. (springeropen.com)
Paragangliomas are vascular tumors and demonstrate avid enhancement on both CT and MR. They also often exhibit a characteristic "salt and pepper" appearance on MR. (springeropen.com)
Paragangliomas, also known as glomus tumors, arise from paraganglion cells which form the basis of the extra-adrenal neuroendocrine system. (springeropen.com)
The imaging evaluation of head and neck paragangliomas utilizes multiple cross-sectional imaging modalities to evaluate for extent of disease and to help guide surgical management by evaluating for osseous and neurovascular involvement. (springeropen.com)
Additionally, familial paragangliomas are more commonly multicentric than sporadic tumors. (springeropen.com)
Preoperative protective stenting of the internal carotid artery in the management of complex head and neck paragangliomas: long-term results. (unipr.it)
Objectives: To investigate the long-term results of preoperative stenting of the internal carotid artery (ICA) in complex head and neck paragangliomas (HNP) as well as to report on indications and technical details of the procedure. (unipr.it)
Fourteen patients were affected by tympanojugular paragangliomas, 4 by vagal paragangliomas and 1 by bilateral carotid body tumors. (unipr.it)
When such tumors arise outside of the adrenal gland, they are termed extra-adrenal pheochromocytomas, or paragangliomas. (medscape.com)

In the United States, the earliest successful carotid body tumor resection was performed by Scudder in 1903. (medscape.com)
Hayes Martin, in his textbook of head and neck tumors, recommended against resection of any tumor that is now considered a Shamblin type III (see Staging). (medscape.com)
A large retrospective, multicenter, international study analyzed the long-term outcome in 132 patients with primary radiation treatment or radiation after partial resection of a glomus tumor. (medscape.com)
Köhler, H.F., Carvalho, A.L., Nishinari, K. and Kowalski, L.P. (2010) Internal Carotid Artery Reconstruction after Paraganglioma Resection: Report of Six Cases and Analysis of Available Techniques. (scirp.org)
She underwent surgery, and resection of the tumor with neck dissection was performed, which was reported as malignant carotid body paraganglioma on histopathology. (cytojournal.com)
Surgical resection of the tumor is the treatment of choice and usually cures the hypertension. (medscape.com)

Some studies estimate that less than 10% of carotid body tumors are malignant (cancerous). (clevelandclinic.org)
Opioids act on the µ-opioid receptor (MOR), which is expressed in cancer cells and non-malignant cells of the tumor microenvironment. (bvsalud.org)
My lab's work has pursued how multiple discrete subpopulations of malignant cells within these tumors cooperatively resist therapy via both tumor cell autonomous mechanisms and crosstalk with the stromal microenvironment. (upenn.edu)
My group seeks precise molecular definition of the epigenetic plasticity that promotes homeostasis of tumor cells that retain malignant potential in the face of standard therapy. (upenn.edu)
Among the features that suggest a malignant course are large tumor size and an abnormal DNA ploidy pattern (aneuploidy, tetraploidy). (medscape.com)
The tumor is malignant in 10% of cases but may be cured completely by surgical removal. (medscape.com)

[ 1 ] These tumors develop within the adventitia of the medial aspect of the carotid bifurcation. (medscape.com)
CECT revealed, in addition, a lobulated, ill-marginated enhancing space-occupying mass in the right carotid bifurcation. (cytojournal.com)
It was in close proximity to right common carotid artery beginning at the level of carotid bifurcation. (cytojournal.com)
A 3-D reconstruction optimized for vasculature (red) shows the location of the highly vascular mass (arrows) lying medial to the right mandibular salivary gland (MSG) at the level of the common carotid artery bifurcation (asterisk). (avma.org)
Carotid body tumor is a rare neoplasm located at the bifurcation of the carotid artery. (pumch.cn)
Eversion carotid endarterectomy (eCEA) involves oblique transection of the internal carotid artery (ICA) at its origin at the carotid bifurcation, followed by extirpation of the plaque by means of eversion and subsequent reimplantation of the ICA into the carotid bulb. (medscape.com)

A carotid body tumor is also called a carotid body paraganglioma or a carotid body chemodectoma. (clevelandclinic.org)
A paraganglioma is a rare neuroendocrine neoplasm that may develop at various body sites (including the head, neck, thorax and abdomen). (wikipedia.org)
Mutations of SDHB play an important role in familial adrenal pheochromocytoma and extra-adrenal paraganglioma (of abdomen and thorax), although there is considerable overlap in the types of tumors associated with SDHB and SDHD gene mutations. (wikipedia.org)
Objective: To report a case of a multiple paraganglioma with 5 concurrent locations and also describe a complication not found in the literature, spontaneous tumor bleeding. (scirp.org)
On the basis of characteristic cytological features, a diagnosis of metastatic neuroendocrine tumor/paraganglioma was suggested. (cytojournal.com)
SDHA is a tumor suppressor gene causing paraganglioma. (jamanetwork.com)

Computed tomography (CT) scanning of the head and neck is also helpful and typically reveals a hypervascular tumor located between the external and internal carotid arteries. (medscape.com)
We are presently exploiting such intra-tumor diversity as a basis to improve the marginal efficacy of current targeted agents in head and neck cancer therapy with new drug combinations. (upenn.edu)
When these cells demonstrate neoplasia within the head and neck, they typically present in characteristic locations including the carotid space, the jugular foramen, the middle ear, and along the course of the vagus nerve. (springeropen.com)
With each chapter written by experts in the many fields that comprise head and neck oncology and surgery, this compendium provides a unique, multidisciplinary perspective on the diagnosis and management of these patients. (novapublishers.com)

Other significant medical history included palpitations, angina, and carotid endarterectomy. (medscape.com)
The reference standard for calculation of the degree of carotid artery stenosis is based on the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria (see the image below). (medscape.com)
North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria. (medscape.com)

Its apex is located next to the tonsillar area in the lateral wall of pharynx, between external and internal carotid arteries. (acbjournal.org)

Healthcare providers often use surgery and embolization to treat carotid body tumors. (clevelandclinic.org)
Transcatheter embolization to stop blood flow to the tumor, which you may have before surgery to help shrink the tumor. (clevelandclinic.org)

Are carotid body tumors benign? (clevelandclinic.org)
Most carotid body tumors are benign (not cancer ). (clevelandclinic.org)

Various imaging studies can be used to confirm the diagnosis of carotid body tumor (CBT), starting with simple ultrasonography with color Doppler, which can assess the vascularity of the neck mass and can sometimes reveal a possibility of a carotid body tumor (CBT), although it is not the best imaging modality to detect these tumors. (medscape.com)
A carotid body tumor is a mass that grows in the blood vessels near the large arteries in either side of your neck (carotid arteries). (clevelandclinic.org)
Carotid body tumors are often painless, but your healthcare provider may want to remove the tumor because it can become large and affect the blood vessels in your neck or cause other symptoms. (clevelandclinic.org)
It usually presents as a painless neck mass, but larger tumors may cause cranial nerve palsies, usually of the vagus nerve and hypoglossal nerve. (wikipedia.org)
Lateral projection image of whole-body FDG-PET shows the focal increased FDG activity in the lower mediastinum (blue arrow) and in the neck (red arrow). (medscape.com)

Carotid body tumors are growths in the blood vessels near your carotid arteries. (clevelandclinic.org)
On color Doppler evaluation, the lesion was observed to lie between the internal and external carotid arteries. (cytojournal.com)
Shamblin's classification is based on the relationship between tumor and carotid arteries, which has limitations. (pumch.cn)
Including both the horizontal relationship to carotid arteries and vertical extension of the tumors, PUMCH (Peking union medical college hospital) classification can better predict surgical complications and guide the surgery and thus might help to improve the surgical outcomes of the lesions. (pumch.cn)
Carotid artery stenosis is a chronic atherosclerotic disease resulting in narrowing of the common and internal carotid arteries. (lecturio.com)
Carotid Artery Stenosis is a narrowing of the common and internal carotid arteries Arteries Arteries are tubular collections of cells that transport oxygenated blood and nutrients from the heart to the tissues of the body. (lecturio.com)

Often, glomus jugulare tumors are diagnosed within the sixth or seventh decade of life and can be followed by imaging only and may not need surgical intervention. (medscape.com)
My NIH-funded research enterprise brings a cutting edge molecular perspective to surgical cancer care while optimizing use of tumors that I remove from patients to advance the science of cancer therapy. (upenn.edu)
I am also highly experienced in surgical management of thyroid and parathyroid diseases. (upenn.edu)
Current surgical management of carotid body tumors[J]. J Vasc Surg, 2016, 64: 1703-1710. (pumch.cn)
Progress in imaging examination and surgical treatment of carotid body tumor[J]. Xueguan Yu Qiangnei Xueguan Waike Zazhi, 2020, 6: 439-441. (pumch.cn)
A Systematic Review and Meta-Analysis of the Presentation and Surgical Management of Patients With Carotid Body Tumours[J]. Eur J Vasc Endovasc Surg, 2019, 57: 477-486. (pumch.cn)
This book places emphasis on the medical, endovascular and surgical approaches in managing patients with extracranial carotid and vertebral artery disease following pertinent diagnostic studies. (nshealth.ca)
Dr. Seib has clinical and research expertise in the surgical management of endocrine disorders in older adults, including primary hyperparathyroidism, thyroid cancer, and hyperthyroidism. (stanford.edu)
She has received funding from the National Institute on Aging and the American Thyroid Association to study the surgical management of endocrine disorders in older adults and has a number of peer-reviewed journal publications on this topic that have received national attention, including being featured in the New York Times. (stanford.edu)
The Center features highly skilled spine specialists on the medical staff, as well as an array of innovative minimally invasive surgical techniques, technologically advanced operating room equipment that allows for real-time imaging and precise navigation, and forward-thinking pain management strategies. (bswhealth.com)
It has been validated in randomized and nonrandomized prospective studies as a safe and effective surgical treatment for carotid stenosis. (medscape.com)
The efficacy of surgical treatment of atherosclerotic carotid stenosis in the prevention of stroke is well documented. (medscape.com)

citation needed] By light microscopy, the differential diagnosis includes related neuroendocrine tumors, such as carcinoid tumor, neuroendocrine carcinoma, and medullary carcinoma of the thyroid. (wikipedia.org)

A. Arterial flow (red) is displayed in internal carotid artery (ICA) and common carotid artery (CCA). (medscape.com)

Carotid body tumors (CBTs) are treated with either surgery or radiotherapy. (medscape.com)
Descriptions of surgery for carotid body tumors have existed for over 100 years. (medscape.com)
Surgery to remove the tumor. (clevelandclinic.org)
Recovery time after surgery for a carotid body tumor is typically three to four weeks. (clevelandclinic.org)
If you have surgery to remove a carotid body tumor, you typically don't need further treatment. (clevelandclinic.org)
Surgery is the treatment of choice for glomus jugulare tumors. (medscape.com)
However, radiation therapy, particularly stereotactic radiosurgery (eg, Gamma Knife surgery), has been shown to provide good tumor growth control with a low risk of treatment-related cranial nerve injury. (medscape.com)
Of 22 patients with glomus jugulare tumors who underwent Gamma Knife surgery, neurologic status improved in 12 patients, 7 showed stable clinical condition, and 3 patients developed new moderate deficits. (medscape.com)
Contributions from many interrelated specialties, including cerebrovascular physiology, pathology, neuro-radiology, neuro-interventions, stroke-neurology and vascular surgery significantly enhance our knowledge of carotid and vertebral artery disease. (nshealth.ca)
Dr. K Dhamodaran is known for excellence in Coronary Angioplasty / Bypass Surgery, Renal, Carotid Artery Disease, Angioplasty, Implantable Cardioverter Defibrillator, Transesophageal Echocardiogram. (myupchar.com)
10] In 2008, the Society for Vascular Surgery (SVS) formulated evidence-based clinical practice recommendations for the management of carotid stenosis. (medscape.com)
11] Generally, carotid surgery is performed if a patient's perioperative stroke or mortality risk is less than 3% and the life expectancy is greater than 5 years. (medscape.com)
An alternative (although one that is less frequently used during catheter-based arteriography) is to determine the degree of the carotid artery stenosis by using the European Carotid Surgery Trial (ECST) criteria. (medscape.com)

They are highly vascular tumors and may have a deep red color. (wikipedia.org)

Are there complications of carotid body tumor treatment? (clevelandclinic.org)
Many people who have treatment for a carotid body tumor don't have complications. (clevelandclinic.org)

Carotid and vertebral artery disease affects a large segment of the population with the potential of causing severe disability from a major stroke. (nshealth.ca)
Brain imaging can detect infarction (stroke), tumors, hemorrhages and bone trauma. (pvillehosp.org)
The most serious complication of carotid artery stenosis is stroke. (lecturio.com)
Several conditions can cause a facial paralysis e.g. stroke, brain tumor and Lyme disease. (krishnaherbals.com)
In addition to high rates of death, recurrence, and long-term disability,[6, 7] management of stroke imposes a substantial economic burden on society. (medscape.com)

Extracranial Carotid and Vertebral Artery Disease: Contemporary Management provides an comprehensive and state-of-the-art approach to managing complex arterial reconstructions. (nshealth.ca)

The peripheral nervous system consists of all your nerves outside of the brain and spinal cord, including those in your arms, legs, and trunk of the body. (medlineplus.gov)
Together, your brain and spinal cord serve as the main "processing center" for the entire nervous system, and control all the functions of your body. (medlineplus.gov)

Various imaging studies can be used to confirm the diagnosis of carotid body tumor (CBT), starting with simple ultrasonography with color Doppler. (medscape.com)
ENT 2023 is an international platform for presenting research about diagnosis, prevention and management and exchanging ideas about it and thus, contributes to the dissemination of knowledge in Rhinology and Otology for the benefit of both the academia and business. (insightconferences.com)
Additionally, the system's exclusive image post-processing solutions can dramatically assist in diagnosis of lung pathologies such as nodules, tumors and vascular lesions. (pvillehosp.org)
Diagnosis is by clinical criteria, hormone measurement, and imaging to exclude a virilizing tumor. (msdmanuals.com)

however, carotid body tumors (CBTs) are considered to be a disease of middle age. (medscape.com)
In this way the examination of the family members of patients, specially young ones, diagnosed with multicentric tumors may lead to negative results which doesn't meant that the disease can be developed at a later time period. (scirp.org)
Subsequent chapters discuss specific disease processes and their management with the best medical therapy neuro-interventions. (nshealth.ca)
The good contrast it provides between the different soft tissues of the body makes it especially useful in diagnosing injuries and disease. (pvillehosp.org)
Operative Management of Thyroid Disease in Older Adults. (stanford.edu)

With regard to laboratory studies, check urinary catecholamines in patients who have any symptoms of a functional carotid body tumor (CBT). (medscape.com)
What are the symptoms of a carotid body tumor? (clevelandclinic.org)
A carotid body tumor may not cause any symptoms, but as the mass grows, it may press on nearby nerves and blood vessels. (clevelandclinic.org)
If your provider recommends observing the tumor (watchful waiting), let them know right away if you develop new symptoms. (clevelandclinic.org)
Therefore routine examination is not justifiable when symptoms relative to tumor presence are not present. (scirp.org)
In routine clinical practice, indications for the treatment of patients with carotid stenosis are based on the presence of symptoms and the degree of stenosis. (medscape.com)

Vagal and Carotid Body Tumors. (scirp.org)

The multicentric lesions can occur at different life stages not being necessarily simultaneous, a fact that prevents image exam research to be conclusive for tumor presence or absence. (scirp.org)

A retrospective study by Davila et al suggested that carotid body tumors also tend to appear at a younger age in patients with succinate dehydrogenase mutations (see Pathophysiology). (medscape.com)

Multidisciplinary management of carotid body tumors: a single-institution case series of 22 patients. (cornell.edu)

Cardiac tumors, chiefly left atrial myxoma, are a rare cause of mitral regurgitation. (health.am)

When the same type of tumor is found in the adrenal gland, they are referred to as a pheochromocytoma. (wikipedia.org)

A study from Vanderbilt University found that in the absence of brainstem compression or concern for malignancy, observation of glomus jugulare tumors can be a viable initial management approach for elderly patients. (medscape.com)
A German study of 32 patients who underwent stereotactic radiosurgery for glomus jugulare tumors showed that stereotactic linear accelerator (LINAC) radiosurgery achieved excellent long-term tumor control, along with a low rate of morbidity. (medscape.com)
In a study of 28 patients treated with radiosurgery and 2 patients with stereotactic radiosurgery, crude overall survival, tumor control, clinical control, and long-term grade 1 toxicity rates were 97%, 97%, 97%, and 13% (4/30), respectively. (medscape.com)
PATIENTS AND METHODS: HER2 expression by IHC was evaluated in 4701 patients with solid tumors. (bvsalud.org)
ERBB2 alterations were identified in 117 (7.5%) patients with non-breast, non-gastric/GEJ solid tumors who had NGS testing. (bvsalud.org)
These findings suggest that many patients with HER2-low solid tumors might benefit from HER2-targeted therapies. (bvsalud.org)
Opioids alone or in combination with non-opioid analgesics and adjuvant medications are important components for pain management during the perioperative period for cancer patients. (bvsalud.org)
Five patients presented with recurrent tumors, while 7 presented with multiple or bilateral HNP. (unipr.it)
This publication is designed to help the primary care practitioner in the day-to-day management of patients with diabetes. (cdc.gov)

Magnetic resonance imaging (MRI) is considered to be the criterion standard for carotid body tumors (CBTs), and the tumor has a characteristic salt and pepper appearance on T1-weighted images. (medscape.com)

RESULTS: HER2 expression (HER2 IHC 1-3+) was found in half (49.8%) of the cancers, with HER2-low (1 or 2+) found in many tumor types: 47.1% in breast, 34.6% in gastric/GEJ, 50.0% in salivary gland, 46.9% in lung, 46.5% in endometrial, 46% in urothelial, and 45.5% of gallbladder cancers. (bvsalud.org)

Dall′Igna, C., Antunes, M.B. and Dall′Igna, D.P. (2005) Radiation Therapy for Glomus Tumors of the Temporal Bone. (scirp.org)

These familial tumors tend to occur earlier than their sporadic counterparts, with a peak prevalence of 30-35 years of age [ 5 ]. (springeropen.com)

Management includes lifestyle modifications to control progression of atherosclerosis. (lecturio.com)

It is one of the first clinics in Bangalore for the management of vascular diseases. (msrmh.com)
Did you mean topic:"carotids artery diseases - physiopathology" ? (nshealth.ca)
BACKGROUND: Vascular diseases are evolving fast in sub-Saharan Africa, but its management is challenged by lack of expertise and infrastructure. (bvsalud.org)

But carotid body tumor treatment can involve many blood vessels. (clevelandclinic.org)
How soon will I feel better after carotid body tumor treatment? (clevelandclinic.org)
No deaths were attributable to tumor progression or treatment. (medscape.com)

Alpha-blockers and beta-blockers are useful for tumors secreting catecholamines. (medscape.com)

The study found long-term successful control of the tumor growthi and mprovement of tinnitus and overall neurological status, as well as cranial nerve function. (medscape.com)
from ophthalmic division of out coming generic cialis is when preotic somitomeres oculomotor nerve (cn vi) ophthalmic n. (cn vii) styloid process to clavicle reinforces the modern management of ed following a dermatome. (ben.edu)

The sporadic form is the most common type, representing approximately 85% of carotid body tumors (CBTs). (medscape.com)

Tumor progression-free survival was 95.5% at 5 and 7 years. (medscape.com)
No tumor progression was observed. (medscape.com)

A deficient bony plate along the tympanic portion of the internal carotid artery (aberrant ICA) is a normal variant and can be mistaken with glomus jugulare. (wikipedia.org)
This controls your internal body processes such as blood pressure, breathing, digestion, and so on. (medlineplus.gov)
Convention for describing carotid stenosis is to compare lumen diameter at most narrow point to diameter of internal carotid artery in normal segment several centimeters distal to stenosis. (medscape.com)

Anatomy4

Diseases8

Chemicals and Drugs1

Paragangliomas15

Resection6

Malignant6

Bifurcation6

Paraganglioma6

Head and neck4

Endarterectomy3

External and internal carotid1

Embolization2

Benign2

Neck5

Arteries6

Surgical12

Neuroendocrine tumors1

Common caroti1

Surgery13

Vascular tumors1

Complications2

Stroke5

Vertebral artery1

Brain2

Diagnosis4

Disease5

Symptoms6

Vagal1

Multicentric1

Retrospective study1

Multidisciplinary1

Cardiac1

Adrenal gland1

Patients9

Characteristic1

Salivary1

Radiation therapy1

Familial1

Atherosclerosis1

Diseases3

Treatment3

Catecholamines1

Nerve2

Sporadic1

Progression2

Internal3