AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaHumanitiesInformation ScienceNamed GroupsHealth CareGeographicals
Vulvar NeoplasmsGenital Neoplasms, FemaleGynecologic Surgical ProceduresOvarian NeoplasmsGynecologyGenital Diseases, FemaleEndometrial NeoplasmsDisease ManagementHysterectomyUterine NeoplasmsNeoplasmsPancreatic NeoplasmsNeoplasms, Glandular and EpithelialUterine Cervical NeoplasmsPeritoneal NeoplasmsTreatment OutcomeFallopian Tube NeoplasmsVaginal NeoplasmsNeoplasms, Cystic, Mucinous, and SerousObstetric Surgical ProceduresRetrospective StudiesLaparoscopyCase ManagementNeoplasm StagingAdenocarcinoma, MucinousCA-125 AntigenPatient Care ManagementCarcinomaSkin NeoplasmsCarcinosarcomaNeoplasm Recurrence, LocalPelvic ExenterationNeoplasms, Multiple PrimaryCystadenocarcinoma, SerousPain ManagementKidney NeoplasmsPrognosisSalpingostomyNeoplasms, Second PrimaryRisk ManagementTumor Markers, BiologicalAdenocarcinoma, Clear CellPaclitaxelImmunohistochemistryThyroid NeoplasmsPelvic NeoplasmsFollow-Up StudiesProspective StudiesMedical OncologyRisk FactorsPostoperative ComplicationsLaparotomyTomography, X-Ray ComputedCisplatinLeiomyosarcomaCystadenocarcinomaMyeloproliferative DisordersLung NeoplasmsVaginal SmearsCarcinoma, EndometrioidLiver NeoplasmsUnited StatesQuality of LifeParotid NeoplasmsAdenocarcinomaPathology, SurgicalBreast NeoplasmsTime FactorsQuestionnairesCystadenomaDNA, NeoplasmAppendiceal NeoplasmsCytodiagnosisEndometrial HyperplasiaAntineoplastic Combined Chemotherapy ProtocolsCombined Modality TherapyAntineoplastic AgentsNeoplasm InvasivenessNeoplasms, Connective and Soft TissueCarboplatinNeoplasms, Plasma CellLeiomyomaDisease-Free SurvivalGastrointestinal NeoplasmsDiagnostic Techniques, Obstetrical and GynecologicalCystadenoma, MucinousVaginitisAntigens, NeoplasmIncidenceSensitivity and SpecificityEndocrine Gland NeoplasmsAlphaprodineEye NeoplasmsInformation ManagementIntraoperative ComplicationsSurvival AnalysisCarcinoma, Pancreatic DuctalPractice Guidelines as TopicPregnancyVagina
TumorsAffecting the vulvar areaDivision of Gynecologic OncologyLymphomaLichen sclerosusVulvaDevelopment of vulvarSquamous cell carcOncologyMalignanciesOncologistIntraepithelial neoplasiaBenignRecurrentInvasiveMelanomaCarcinomaTumorHuman papillomavirusTumoursPrecursorsEndometrialClinicalNeuroendocrineInhibitorsPatientsSubtypesTransformationPathwaysOccurCancer TreatmentBiopsyDisordersCancers of the femaleMass2019TissuesDiagnosis and managementDiseaseSurgeryMesotheliomaBreast cancerHistoryCommonTopicalTreatment
Tumors5
  • The effective control of vulvar tumors by electrochemotherapy may contribute to improvement of quality-of-life. (bmj.com)
  • Benign ovarian tumors usually grow slowly and rarely become malignant. (msdmanuals.com)
  • Wang MX, Devine C , Segaran N, Ganeshan D . Current update on molecular cytogenetics, diagnosis and management of gastrointestinal stromal tumors. (viictr.org)
  • Although this most common gynecologic cancer carries the best prognosis, it is important to differentiate between the classic endometrioid tumors that tend to be estrogen dependent and well differentiated, from other less common high-risk uterine malignancies, such as uterine papillary serous carcinomas (UPSCs), clear cell carcinomas, mixed mullerian tumors (MMTs), or sarcomas, which appear to have a different biology. (medmuv.com)
  • Most often, these tumors are benign, although it is possible for them to be malignant and to spread or metastasize. (moffitt.org)
Affecting the vulvar area2
  • Two main pathophysiological pathways are currently understood to contribute to development of vulvar cancer-human papillomavirus (HPV) infection and chronic inflammation or autoimmunity affecting the vulvar area. (wikipedia.org)
  • Vulvar inflammatory disorders (VID) are a miscellaneous group of non-infectious conditions affecting the vulvar area that are characterized predominantly by inflammation. (jsstd.org)
Division of Gynecologic Oncology1
  • The Division of Gynecologic Oncology provides state-of- the- art comprehensive care for women with preinvasive and invasive gynecologic malignancies including those of the cervix, uterus, vulva, tubes ovaries and peritoneum. (montefiore.org)
Lymphoma4
  • Nodal Malignant Lymphoma (With Comments on Extranodal Malignant Lymphoma and Metastatic Cancer) -- Part IX. (nshealth.ca)
  • A group of disorders having a benign course but exhibiting clinical and histological features suggestive of malignant lymphoma. (lookformedical.com)
  • Pseudolymphoma is characterized by a benign infiltration of lymphoid cells or histiocytes which microscopically resembles a malignant lymphoma. (lookformedical.com)
  • Malignant blast cells (i.e. diffuse large B-cell lymphoma) are fast-growing and result in aggressive disease, whereas malignant mature lymphocytes (i.e. follicular lymphoma) behave indolently. (oncolink.org)
Lichen sclerosus3
  • Chronic inflammatory conditions of the vulva that may be precursors to vulvar cancer include lichen sclerosus, which can predispose to differentiated VIN. (wikipedia.org)
  • Differentiated vulvar intraepithelial neoplasia (dVIN), which is associated with chronic skin conditions including lichen sclerosus and lichen planus and typically affects older women. (wikipedia.org)
  • A 51-year-old patient presents for evaluation of possible vulvar lichen sclerosus. (contemporaryobgyn.net)
Vulva4
  • Vulvar cancer is a cancer of the vulva, the outer portion of the female genitals. (wikipedia.org)
  • Clinically, he sees patients with neoplasms of the cervix, vulva, and vagina as well as endometrial and ovarian cancer. (montefiore.org)
  • This summary addresses squamous cell cancer of the vulva and vulvar intraepithelial neoplasias (VIN), some of which are thought to be precursors to invasive squamous cell cancers. (cancer.gov)
  • Invasive and preinvasive neoplasms of the vulva may be HPV-induced, and the carcinogenic effect may be widespread in the vulvar epithelium. (cancer.gov)
Development of vulvar1
  • Human papillomavirus (HPV) infection: In many cases, the development of vulvar cancer is preceded by condyloma or squamous dysplasia. (cancer.gov)
Squamous cell carc2
  • A recent analysis of the Surveillance, Epidemiology and End Results (SEER) registry of the US National Cancer Institute has shown that squamous cell carcinoma accounts for approximately 75% of all vulvar cancers. (wikipedia.org)
  • Condyloma accummatum was the most common benign tumour while squamous cell carcinoma was the most common malignant tumour. (bvsalud.org)
Oncology5
  • The Division participates in many cooperative group trials through the Gynecologic Oncology Group (GOG), the New York GOG, as well as having access to many Phase I drugs released from the National Cancer Institute (NCI). (montefiore.org)
  • The faculty are Board Certified or Eligible in Gynecologic Oncology. (montefiore.org)
  • The Division has Gynecologic Oncology fellowship-training program, one of only 30 in the United States, and attracts and recruits outstanding fellows and junior faculty. (montefiore.org)
  • The patient was referred to Michigan Medicine Hematology/Oncology clinic for further evaluation and management of the underlying disease. (contemporaryobgyn.net)
  • Squamous vulvar intraepithelial neoplasia: 2004 modified terminology, ISSVD Vulvar Oncology Subcommittee. (cancer.gov)
Malignancies3
  • She also specializes in novel chemotherapeutics for advanced disease as well as being a nationally recognized specialist in radical resections/reconstruction for gynecologic malignancies. (montefiore.org)
  • Ovarian cancer, uterine cervical cancer, endometrial cancer, and trophoblastic neoplasms are gynecologic malignancies for which tumor markers are in clinical use. (medscape.com)
  • Vulvar cancer is a rare disease, accounting for 2% to 5% of all gynecological malignancies. (bmj.com)
Oncologist2
  • The Director of the division is Gary L Goldberg , MD, a nationally and internationally known gynecologic oncologist. (montefiore.org)
  • Everybody agrees that these women are in pain and aren't being well served by the current medical community," said Caela Miller, MD, assistant professor and gynecologic oncologist at the San Antonio Military Medical Center. (medscape.com)
Intraepithelial neoplasia1
  • There are two types of precursor lesions: Usual-type vulvar intraepithelial neoplasia (uVIN), which is associated with human papillomavirus (HPV) and often affects younger women. (wikipedia.org)
Benign4
  • Benign ovarian masses include functional cysts (eg, corpus luteum cysts) and neoplasms (eg, benign teratomas). (msdmanuals.com)
  • Twenty nine (72.5) were benign and eleven (27.5) were malignant. (bvsalud.org)
  • Mature teratomas generally are benign, with 0.17-2% of mature cystic teratomas becoming malignant. (mdwiki.org)
  • The pathogenesis of leiomyoma is characterized by benign smooth muscle neoplasm . (wikidoc.org)
Recurrent2
  • To our knowledge this is the first reported case of an isolated vesicocutaneous fistula related to previous radiation therapy for recurrent vulvar cancer. (annals.edu.sg)
  • The mainstay of treatment for recurrent vulvar cancer is surgery;however, for some cases, adequate excision of the tumor with clear margins can solely be achieved by exenteration and the formation of bowel and/or urinary stoma. (bmj.com)
Invasive4
  • Our practice offers outpatient care/consultations, minimally invasive and radical surgery as well as chemotherapeutic management for women with gynecologic disease. (montefiore.org)
  • Dr Guiseppe Del Priore has expertise in fertility sparing in patients with gynecologic cancer and is a surgeon who employs minimally invasive techniques. (montefiore.org)
  • More than 90% of invasive vulvar cancers are squamous cell carcinomas. (cancer.gov)
  • Conclusions Electrochemotherapy is an effective and minimally invasive treatment modality in the palliative care management of patients with vulvar cancer. (bmj.com)
Melanoma1
  • Malignant Melanoma -- Part V. Breast Cancer -- 22. (nshealth.ca)
Carcinoma2
  • The labia majora are the most common sites of vulvar carcinoma and account for about 50% of cases. (cancer.gov)
  • The labia minora account for 15% to 20% of vulvar carcinoma cases. (cancer.gov)
Tumor1
Human papillomavirus1
  • Effect of human papillomavirus vaccines on vulvar, vaginal, and anal intraepithelial lesions and vulvar cancer. (cancer.gov)
Tumours1
  • It is concluded that vulval tumours are rare in this environment and that the malignant variants present at advanced stage of the disease in later ages. (bvsalud.org)
Precursors1
  • Most of the cervical epithelial neoplasms and their precursors occur at the squamocolumnar junction or within the transformation zone. (cytojournal.com)
Endometrial2
  • He has expertise and special interest in the management of patients with ovarian, endometrial, uterine, vulvar and cervical cancer and is referred patients for complex and radical cancer, reconstructive and other surgery. (montefiore.org)
  • Among sporadic endometrial cancers, when present, the microsatellite instability is confined to the malignant cells, and is not seen in the adjacent normal epithelium. (medmuv.com)
Clinical4
  • In addition to the clinical interests and responsibilities, our faculty is all involved academically with investigations focused on innovative strategies t o improve cancer diagnosis, management and outcomes. (montefiore.org)
  • Dr. Einstein is a NIH clinical investigator with funding focused in the pathways to the malignant transformation of cervical cancer. (montefiore.org)
  • SCC antigen is useful in the clinical management of advanced cervical cancer. (medscape.com)
  • Virarkar M, Jensen C, Klekers A , Wagner-Bartak NA , Devine CE , Lano EA , Sun J, Tharakeswara B, Bhosale P. Clinical importance of second-opinion interpretations of abdominal imaging studies in a cancer hospital and its impact on patient management. (viictr.org)
Neuroendocrine1
  • Segaran N, Devine C , Wang M, Ganeshan D . Current update on imaging for pancreatic neuroendocrine neoplasms. (viictr.org)
Inhibitors2
  • Potent topical steroids are the first line management in most cases, followed by topical calcineurin inhibitors, emollients, and antihistamines. (jsstd.org)
  • Treatment of moderate to severe vasomotor symptoms due to menopause )  Treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to Limitation of Use: When prescribing solely for the treatment of moderate to severe Inducers and/or inhibitors of CYP3A4 may affect estrogen drug metabolism. (gotomydoctor.com)
Patients3
  • There are 4 other gynecologic oncologists in the division and they all have expertise in the management of patients with cancers of the female reproductive tract. (montefiore.org)
  • Histopathology Reporting: Guidelines for Surgical Cancer, Fourth Edition is invaluable for trainee and consultant diagnostic histopathologists all over the world, equipping the reader to produce high quality, clinically appropriate histopathology reports, and to participate in contemporary multidisciplinary team management of patients with surgical cancer. (nshealth.ca)
  • Biopsy methods for accurate histologic or cytologic proof of malignancy are absolutely essential to workup and subsequent management of suspected cancer patients. (oncolink.org)
Subtypes1
  • Depending on the cellular origin, different histologic cancer subtypes may arise in vulvar structures. (wikipedia.org)
Transformation1
  • Malignant transformation is usually the result of chromosomal translocations that activate proto-oncogenes or create a chimeric fusion protein. (oncolink.org)
Pathways1
  • Risk factors for vulvar cancer are largely related to the causal pathways above, involving exposure or infection with the HPV virus and/or acquired or innate auto-immunity. (wikipedia.org)
Occur1
  • Autoimmune vesiculobullous conditions, drug-induced vulvar dermatoses and many such, which occur as part of generalized disease, are not discussed here. (jsstd.org)
Cancer Treatment1
  • Methods The following databases were searched: MEDLINE, Scopus, and Cochrane Database, to identify all registered articles pertaining to palliative vulvar cancer treatment with electrochemotherapy from inception until August 2019, in line with PRISMA guidelines. (bmj.com)
Biopsy1
  • A thorough history taking and relevant investigations including dermoscopy and biopsy are relevant to proper diagnosis and management of VID. (jsstd.org)
Disorders2
  • Prabhu S, Krishna S. Vulvar inflammatory disorders: A review. (jsstd.org)
  • Vulvar inflammatory disorders (VID) are a miscellaneous group of non-infectious conditions of the vulvar area, which can be broadly classified based on etiology and pathology. (jsstd.org)
Cancers of the female1
Mass1
  • The exam may reveal an ulceration, lump or mass in the vulvar region. (wikipedia.org)
20191
  • The 2019 Fall Update: Management of Not So Rare Cancers conference was held on Saturday October 5 at the Four Seasons Hotel in Vancouver. (bccancer.bc.ca)
Tissues1
  • Immature teratoma is the malignant counterpart of the mature teratoma and contains immature tissues which typically show primitive or embryonal neuroectodermal histopathology. (mdwiki.org)
Diagnosis and management1
Disease2
  • The nature of disease (indolent vs. aggressive) is correlated to the stage of lymphocytic differentiation of the malignant cells. (oncolink.org)
  • It is most applicable for malignant disease in the central nervous system, spine, head and neck and musculoskeletal system, aiding in detection, localization and staging. (oncolink.org)
Surgery1
  • Urogenital fistulas are a known but uncommon complication of gynaecological surgery, especially those involving a malignant process. (annals.edu.sg)
Mesothelioma1
Breast cancer1
  • CHICAGO - The application of topical liquid lidocaine to the vulvar vestibule allows for comfortable intercourse in breast cancer survivors with severe menopausal dyspareunia, new research shows. (medscape.com)
History1
Common1
  • Ovarian cysts or other ovarian masses are a common gynecologic issue. (msdmanuals.com)
Topical2
  • Patient had no improvement with topical clobetasol ointment 0.05% for 1 month and therefore was referred to Michigan Medicine Center for Vulvar Diseases for further evaluation. (contemporaryobgyn.net)
  • When prescribing solely for the treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause, topical vaginal products should be considered. (pillintrip.com)
Treatment5
  • She then showed them the vulvar vestibule, where the pain was localized, and taught them how to apply the 3-minute treatment prior to penetration. (medscape.com)
  • It has recently emerged as an alternative treatment modality in vulvar cancer. (bmj.com)
  • Management is with antihypertensives and magnesium sulfate for seizure prophylaxis or treatment, depending on the presentation. (lecturio.com)
  • Treatment includes conservative management with lifestyle modifications, oral medications, and injectables. (lecturio.com)
  • Start therapy with DOTTI 0.0375 mg/day applied to the skin twice weekly for the treatment of moderate to severe vasomotor symptoms due to menopause or moderate to severe symptoms of vulvar and vaginal atrophy symptoms due to menopause. (nih.gov)