Loading...
  • embryogenesis
  • In early embryogenesis of most eutherian mammals, the inner cell mass (abbreviated ICM and also known as the embryoblast in mammals or pluriblast) is the mass of cells inside the primordial embryo that, once fertilized, will eventually give rise to the definitive structures of the fetus. (wikipedia.org)
  • There is also interspecies variation in gene expression patterns in early embryos The ICM and the TE will generate distinctly different cell types as implantation starts and embryogenesis continues. (wikipedia.org)
  • Demethylation of early embryogenesis occurs in the preimplantation period in two stages - initially in the zygote, then the first few embryonic replication cycles of morula and blastula. (wikipedia.org)
  • fertilization
  • Following fertilization in the oviduct, the mammalian embryo undergoes a relatively slow round of cleavages to produce an eight cell morula. (wikipedia.org)
  • The vegetal plate and animal hemisphere develop and secrete a hatching enzyme that digests the fertilization envelope and allows the embryo to now become a free-swimming hatched blastula. (wikipedia.org)
  • endoderm
  • The primitive endoderm develops into the amniotic sac which forms the fluid-filled cavity that the embryo resides in during pregnancy. (wikipedia.org)
  • early
  • In this review, we summarize current knowledge on the causes and consequences of aneuploidy in hPSCs and highlight the potential links with genetic changes observed in human cancers and early embryos. (springer.com)
  • Immunological Staining of Global Changes in DNA Methylation in the Early Mammalian Embryo. (edu.au)
  • He was the first to apply clonal analysis to study cell fate and potency in mammals, and used this strategy to provide conclusive evidence against early segregation of the mammalian germline. (wikipedia.org)
  • However, due to the variability and regulative nature of mammalian embryos, experimental evidence for establishing these early fates remains incomplete. (wikipedia.org)
  • The extraembryonic tissues (which give rise to the placenta and other tissues supporting the embryo) retain this early imprinted inactivation, and thus only the maternal X chromosome is active in these tissues. (wikipedia.org)
  • It establishes a connection between the mother and the early embryo which will continue through the remainder of the pregnancy. (wikipedia.org)
  • Therefore, the level of Oct-4 expression in mice is vital for regulating pluripotency and early cell differentiation since one of its main functions is to keep the embryo from differentiating. (wikipedia.org)
  • blastocoel
  • It can be described as the first cell cavity formed as the embryo enlarges, the essential precursor for the differentiated, topologically distinct, gastrula An amphibian embryo in the 128- cell stage is considered a blastula as the blastocoel in the embryo becomes apparent during this stage. (wikipedia.org)
  • At the 120- cell stage, the sea urchin embryo is considered a blastula because of its developed blastocoel, which every embryonic cell surrounds and touches. (wikipedia.org)
  • The accumulation of sodium pulls in water osmotically, creating and enlarging the blastocoel within the mammalian embryo. (wikipedia.org)
  • epigenetic
  • This reprogramming is likely required for totipotency of the newly formed embryo and erasure of acquired epigenetic changes. (wikipedia.org)
  • blastomeres
  • Even as the blastomeres continue to divide, the blastula remains one-cell thick and thins out as the embryo expands outward. (wikipedia.org)
  • 1997
  • Ian Wilmut and Keith Campbell were the first to demonstrate that an adult mammalian cell could be reprogrammed back into a pluripotent state when they cloned Dolly the sheep in 1997. (wikipedia.org)