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  • lineages
  • Only one of these lineages, the epiblast, contributes to the embryo itself, while the other two lineages, the trophectoderm and the primitive endoderm, become extra-embryonic tissues. (jci.org)
  • Knowledge about how these lineages develop during the preimplantation period has major clinical implications for increasing the success of assisted reproductive strategies (ARTs) such as in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD), preventing the high rate of early pregnancy loss in humans, and improving the derivation of stem cell lines from human embryos. (jci.org)
  • development
  • Much of what we know about preimplantation development has come from studies in the mouse, which has been used as a model for the early human embryo for over 40 years. (jci.org)
  • Mice
  • Mice embryos that carried experimentally introduced mutations in the FGD1 gene had skeletal abnormalities affecting bone size, cartilage growth, vertebrae formation and distal extremities. (wikipedia.org)
  • cell
  • While regarded by many top scientists as the Holy Grail of medicine, others consider embryonic stem-cell research sacrilegious. (thefutureofthings.com)
  • This laboratory aims are to foster safe and effective use of assisted reproductive technologies and embryonic stem cell therapy. (edu.au)
  • There is also interspecies variation in gene expression patterns in early embryos The ICM and the TE will generate distinctly different cell types as implantation starts and embryogenesis continues. (wikipedia.org)
  • Mammals
  • Delayed implantation or embryonic diapause is a reproductive strategy used by approximately 100 different mammals in seven or eight different orders. (wikipedia.org)
  • Some mammals that undergo embryonic diapause include rodents, bears, mustelids (e.g. weasels and badgers), and marsupials, (e.g. kangaroos). (wikipedia.org)
  • Mammals use embryonic diapause to time the birth of their offspring for favorable metabolic and/or environmental conditions. (wikipedia.org)
  • adult
  • De Beer anticipated evolutionary developmental biology in his 1930 book Embryos and Ancestors, showing that evolution could occur by heterochrony, such as in paedomorphosis, the retention of juvenile features in the adult. (wikipedia.org)
  • sperm
  • Developmental Effects Resulting from Exposure to X-Rays: I. Effect on the Embryo of Irradiation of Frog Sperm. (wikipedia.org)
  • posterior
  • It forms on the dorsal (back) face of the developing embryo, toward the caudal or posterior end. (wikipedia.org)
  • Similarly, Vg1 (a TGFB family member) misexpression and grafts of the posterior marginal zone in chicks can also induce ectopic streaks, but only within the marginal zone of the embryo, indicating a specific characteristic of this region in its ability to induce streak formation. (wikipedia.org)
  • The posterior pole of the embryo contains necessary materials for the fertility of the fly. (wikipedia.org)